23 results for "EAAT2/GLT1" in Products
EAAT2/GLT1 Products
GLT1 is the major glial glutamate transporter that takes up more than 90% of glutamate from the synapse. GLT1b is a splice variant that contains 11 unique amino acids at the C-terminus that encode a PDZ binding domain. GLT1b was initially believed to be the neuronal isoform of GLT1, but it now appears that GLT1b is localized to astrocytes in the normal brain and to neurons in pathological conditions. In Lou Gehrig's Disease, GLT1a is decreased, while GLT1b is increased. There are also different expressions in hypoxic cells, which have not yet been fully elucidated.
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, ICC/IF, Func |
![Western Blot: EAAT2/GLT1 AntibodyAzide Free [NBP1-20136]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody---Azide-Free-Western-Blot-NBP1-20136-img0002.jpg "Western Blot: EAAT2/GLT1 AntibodyAzide Free [NBP1-20136]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: EAAT2/GLT1 Antibody [NBP1-59632]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-Western-Blot-NBP1-59632-img0015.jpg "Western Blot: EAAT2/GLT1 Antibody [NBP1-59632]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: EAAT2/GLT1 Antibody [NBP1-84027]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-Immunohistochemistry-Paraffin-NBP1-84027-img0007.jpg "Immunohistochemistry-Paraffin: EAAT2/GLT1 Antibody [NBP1-84027]")
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: EAAT2/GLT1 Antibody [NBP3-13348]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-Western-Blot-NBP3-13348-img0001.jpg "Western Blot: EAAT2/GLT1 Antibody [NBP3-13348]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #PS01-62 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: EAAT2/GLT1 Antibody [NBP3-17032]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-Immunohistochemistry-Paraffin-NBP3-17032-img0002.jpg "Immunohistochemistry-Paraffin: EAAT2/GLT1 Antibody [NBP3-17032]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: EAAT2/GLT1 Antibody [NBP1-59633]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-Western-Blot-NBP1-59633-img0001.jpg "Western Blot: EAAT2/GLT1 Antibody [NBP1-59633]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #28F9 |
| Applications: | WB, ELISA, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2082 |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1D8 |
| Applications: | WB, ELISA |
![Western Blot: EAAT2/GLT1 Antibody (1D8) [H00006506-M07]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-1D8-Western-Blot-H00006506-M07-img0003.jpg "Western Blot: EAAT2/GLT1 Antibody (1D8) [H00006506-M07]")
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4G8 |
| Applications: | WB, ELISA |
![ELISA: EAAT2/GLT1 Antibody (4G8) [H00006506-M10]](https://resources.rndsystems.com/images/products/EAAT2-GLT1-Antibody-4G8-ELISA-H00006506-M10-img0001.jpg "ELISA: EAAT2/GLT1 Antibody (4G8) [H00006506-M10]")
| Reactivity: | Human |
| Sensitivity: | 0.113 ng/mL (example only; lot dependent) |
| Assay Range: | 0.312 - 20 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.113 ng/mL (example only; lot dependent) |
| Assay Range: | 0.312 - 20 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
Selective non-transportable inhibitor of EAATs
| Chemical Name: | DL-threo-β-Benzyloxyaspartic acid |
| Purity: | ≥98% |
Potent and selective positive allosteric modulator of EAAT2
| Chemical Name: | 3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one |
| Purity: | ≥98% |
Potent, non-substrate EAAT2 inhibitor
| Chemical Name: | N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine |
| Purity: | ≥98% |
Potent competitive inhibitor of L-glutamate uptake
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% |
EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
| Chemical Name: | (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid |
