8 results for "Glucagon-Like Peptide 1 Receptor Agonists Small Molecules and Peptides" in Products
Glucagon-Like Peptide 1 Receptor Agonists Small Molecules and Peptides
Glucagon-like peptide 1 (GLP-1) receptors are members of the glucagon receptor family that also includes glucagon, GLP-2, secretin, GHRH and GIP receptors. GLP-1 receptors are found both centrally (hypothalamus and brainstem) and peripherally (pancreatic islet cells, stomach and heart).
GLP-1 receptors mediate the effects of the incretin axis; the functional connection between the intestine and the islets of Langerhans in the pancreas. Activation stimulates insulin release from the islet β-cells in a glucose-dependent manner and suppresses glucagon secretion from islet α-cells. In addition, GLP-1 receptors delay gastric emptying and regulate appetite. The human GLP-1 receptor gene is localized on chromosome 6p21.
Potent GLP-1 receptor agonist
| Alternate Names: | Exenatide,AC 2993 |
| Purity: | ≥95% |
Highly potent, long-acting GLP-1 receptor agonist
| Alternate Names: | NN2211 |
| Purity: | ≥95% |
Potent insulinotropic peptide
| Alternate Names: | GLP-1 (7-36) amide |
| Purity: | ≥95% |
Endogenous pancreatic peptide
| Alternate Names: | GLP-1 (1-37) amide |
| Purity: | ≥95% |
Endogenous bioactive GLP-1 receptor ligand
| Purity: | ≥95% |
GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist
| Chemical Name: | 6,7-Dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-2-quinoxalinamine |
| Purity: | ≥98% |
Highly potent, long-acting GLP-1 receptor agonist
| Alternate Names: | NN-9535,NNC0480-0389 |
| Purity: | ≥95% |
Non-peptide GLP-1 receptor agonist
| Alternate Names: | OWL833,GLP-1 receptor agonist 1 |
| Chemical Name: | 3-[(1S,2S)-1-[2-[[(4S)-2-(4-Fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2,3-dihydro-2-oxo-1H-imidazol-1-yl]-2,4,6,7-tetrahydro-4-methyl-5H-pyrazolo[4,3-c]pyridin-5-yl]carbonyl]-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indol-1-yl]-2-methylcyclopropyl]-1,2,4-oxadiazol-5(2H)-one |
| Purity: | ≥98% |
