Notch-1: Products

Notch proteins (so named for 'notches' in fly wings) are type I transmembrane glycoproteins involved in specifying cell fates and defining boundaries between different cell types during developmental processes.

The four mammalian Notch receptors appear to have distinct functions, since they do not compensate for one another in genetic studies. Mutations in Notch receptors also lead to specific developmental disorders. For example, Notch-3 is predominantly expressed in the developing central nervous system of mice. Mutations in Notch-3 in humans cause an autosomal dominant condition called CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy). This disorder is characterized by recurrent ischemic strokes at an early age without any underlying vascular risk and progressive dementia.

"Notch-1" has 35 results in Products.
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Mouse/Rat Notch-1 Antibody 

3 Images
B/N, CyTOF-ready, Flow, ICC/IF, IHC, WB

Human Notch-1 Intracellular Domain Antibody 

3 Images
ChIP, CyTOF-ready, Flow, ICC/IF, WB

Mouse Notch-1 Antibody 

Mouse Notch-1 Antibody 

1 Image
CyTOF-ready, Flow

Human Notch-1 Antibody 

1 Image
CyTOF-ready, ELISA(Cap), Flow

Human Notch-1 Antibody 

SAHM1 

Notch pathway inhibitor; prevents Notch complex assembly

Human Notch-1 Biotinylated Antibody 

ELISA(Det)

Human Notch-1 Intracellular Domain Antibody 

ICC/IF, WB

Proteome Profiler Human sReceptor Array, Non-hematopoietic 

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
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