7 results for "Prostanoid Receptor Agonists Small Molecules and Peptides" in Products

Prostanoid Receptor Agonists Small Molecules and Peptides

Prostanoid receptors are activated by the endogenous ligands prostaglandin (PG) D2, PGE2, PGF, PGH2, prostacyclin (PGI2) and thromboxane A2. Cyclooxygenase (COX) converts arachidonic acid to PGH2, from which the other prostaglandins are synthesized. Prostanoid receptors are a family of nine G-protein-coupled receptors that have distinct tissue distributions and actions.

  1. DP receptors (DP1-2) are coupled to Gαs. They are expressed in the small intestine, lung, stomach and uterus. ...
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Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

Alternate Names: PGE2
Chemical Name: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid
Purity: ≥98%
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
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Potent, stable thromboxane A2 (TP) receptor agonist

Alternate Names: 9,11-Dideoxy-9a,11a-methanoepoxy prostaglandin F2a
Chemical Name: (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid
Purity: ≥98%
Potent, stable thromboxane A2 (TP) receptor agonist
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Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development

Chemical Name: (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid
Purity: ≥95%
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
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Endogenous IP receptor agonist

Alternate Names: Prostaglandin I2,Prostacyclin
Chemical Name: (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
Purity: ≥98%
Endogenous IP receptor agonist
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Naturally-occurring prostanoid; potent vasoconstrictor

Chemical Name: 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
Purity: ≥98%
Naturally-occurring prostanoid; potent vasoconstrictor
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Selective EP4 agonist

Chemical Name: (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone
Purity: ≥98%
Selective EP4 agonist
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Potent prostacyclin (PGI2) analog

Chemical Name: 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid
Purity: ≥98%
Potent prostacyclin (PGI2) analog
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