SMURF2: Products

SMURF-2 (SMAD ubiquitin regulatory factor-2) is an approximately 86 kDa, 748 amino acid cytoplasmic E3 ubiquitin ligase that negatively regulates TGF-beta signaling by promoting proteasomal degradation of some SMAD signaling molecules.

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HECT E3 ubiquitin ligase inhibitor
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