We have captured this month's most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.
A significant number of blood cancers have something in common, a mutation in the TET2 gene. This gene encodes an enzyme...
One of the challenges of moving into a new research field or expanding your current field of study is determining the best markers to identify the cells you want. R&D Systems has been providing researchers with reliable tools for defining cell populations for over 30 years. Now we’ve added new Cell Marker Tools for Atherosclerosis, Asthma, and...
Immunotherapy has revolutionized the way we treat cancer. Ground breaking studies have demonstrated that co-signaling molecules such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death 1 (PD-1) receptor, and programmed death ligand 1 (PD-L1) are an important therapeutic targets. However, these victories have been tempered by the development of acquired resistance in some cases. Why is this happening? What are the mechanisms of acquired resistance to immune checkpoint blockade?
Zika virus (ZIKV) is a mosquito-borne, single-stranded, positive-sense RNA virus belonging to the Flaviviridae family. It is closely related to other members of the Flavivirus genus including dengue virus, West Nile virus, yellow fever virus, tick-borne encephalitis virus, and Japanese encephalitis virus. ZIKV was first isolated from a rhesus monkey in Uganda in 1947 and the first human cases were detected in the 1950s in Uganda, Tanzania, and Nigeria. Since that time, there have been significant outbreaks in Africa, Southeast Asia, and the Pacific Islands, but the...
July 2017 Go Everywhere with Bio-Techne Travel Grant Awarded to PhD Student from the University of Lisbon!
Bio-Techne launched its Go Everywhere Travel Grant Program which awards $1000 USD (or equivalent) to 1 researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration.
The recipient of the July 2017 grant is Pedro Papotto, a PhD Student at the Institute of Molecular Medicine at the University of Lisbon in Portugal!
The World Congress on Inflammation (WCI 2017) is a prestigious biennial international conference that brings together scientists from around the world to discuss the latest developments in inflammation research. Bio-Techne attended this year’s exciting Congress from July 8th-12th organized by the British Inflammation Research Association (BIRAs). The plenary lectures were presented by leading researchers on topics ranging from inflammation in aging, neuroinflammation, innate immune memory, regulation of inflammation, microbiome and inflammatory bowel disease. Here are some highlights that we discovered from the meeting....
The Society for Neuroscience Annual Meeting is the largest scientific conference for neuroscientists in the world. This year, approximately 30,000 researchers will gather in Washington D.C. from November 11-15, 2017 to share their work, learn new ways...
Alzheimer's disease, a progressive, neurodegenerative disease of the central nervous system, is the most common form of dementia. It is estimated that 44 million people worldwide have Alzheimer’s disease or a related dementia. Alzheimer’s disease has proved difficult to treat, mainly because the symptoms of the disease only emerge years after disease onset. The treatments that are currently available for Alzheimer’s disease only help to ease the symptoms of the disease; they do not slow or stop its progression. The goal of Alzheimer’s disease research is to develop effective therapies that stop or prevent the underlying cause of the disease.
In a recent edition of...
We have captured this month's most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.
In July, the countries of Germany and Poland announced the Dioscuri Programme, which will fund research efforts across Western and Eastern Europe. This program will provide funding for ten...
Antibody validation and specificity are not new headlines in the research community. Recent comparisons of R&D Systems® Human/Mouse ROR gamma t Recombinant Monoclonal Antibody (Clone # 1181A) to other ROR gamma t clones, demonstrate its superior performance. The data shown below suggest that a popular clone from another supplier is giving false negatives in mouse Th17-differentiated splenocytes and has markedly lower staining of ROR gamma t in human Th17 cells. R&D Systems strives to produce the highest quality...
June 2017 Go Everywhere with Bio-Techne Travel Grant Awarded to PhD Student from the Indian Institute of Chemical Biology!
Bio-Techne launched its Go Everywhere Travel Grant Program which awards $1000 USD (or equivalent) to 1 researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration.
The recipient of the June 2017 grant is Titli Nargis, a PhD Student at CSIR-Indian Institute of Chemical biology in...
We have captured this month's most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.
It was another exciting year for science at the 2017 International Society for Stem Cell Research (ISSCR) Meeting! Playing on the meeting theme, ‘Science Insightfully Delivered’, there was a palatable emphasis in presentation topics focusing on translating stem cell research to the clinic. The translational aspect was complemented by some great posters and lectures highlighting cutting-edge science being done by the stem cell research community. Here are a couple of scientific hits and themes that we identified from the meeting.
When selecting an ELISA kit, different users often have different criteria in making their choice, whether it is sensitivity, sample types, or ease-of-use. One universal criterion is that an ELISA must work the first time and every time you use it. R&D Systems has developed our
Quantikine® ELISAs from raw materials that we make in-house, giving us unparalleled control over critical elements that affect your results and creating consistency of results over long periods of time. Whether you are breaking new ground or building on the work of others, you can trust that the results will be reproducible tomorrow, next week, and...
The generation of induced pluripotent stem (iPS) cells has become a routine task in many laboratories. Across the globe, scientists are using published or commercial reprogramming methods to create iPS cells that further their studies in regenerative medicine, disease modeling, and drug discovery. As we noted in a previous blog post, questions about experimental reproducibility are percolating to the top of major issues that the stem cell field must address in order to confidently guide basic...
May 2017 Go Everywhere with Bio-Techne Travel Grant Awarded to PhD Candidate from Griffith Institute for Drug Discovery!
Bio-Techne launched its Go Everywhere Travel Grant Program which awards $1000 USD (or equivalent) to 1 researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration.
The recipient of the May 2017 grant is Hannah Leeson, a PhD Candidate at Griffith University in Nathan, Australia!
The butyrophilins are closely...
Anthony Person, PhD, Manager in Bioassay Development at Bio-Techne
Scott Schachtele, PhD, Product Manager at Bio-Techne
Blockade of CTLA-4 and PD-1, members of the B7/CD28 family, have proven to be the most successful cancer immunotherapies to date. While the current therapeutic focus remains on B7/CD28 family members, novel immunoregulatory pathways are being uncovered as potential targets for oncology research and cancer immunotherapy. In this presentation, we discuss some of the next generation of novel immune checkpoint molecules, including Butyrophilins (BTNs), leukocyte...
We have captured this month's most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.
SMER28 and iPSCs Pave Possible New Treatment Option for Anemic Patients – Harvard News
Researchers from Boston Children’s Hospital have, for the first time, used patient-derived iPSCs to create red blood cells in humans with Diamond-Blackfan Anemia (DBA). DBA patients lack the erythroid cells needed to generate mature red blood cells. The team of researchers, which includes George Q. Daley and Leonard Zon, performed a chemical screening of...
It recently came to our attention, from this article, that only one in three Americans can name an actual living scientist. As a large biotechnology company, filled with talented and dedicated scientists, we think that is ridiculous. We want to introduce you to some of our staff who are, in fact, Actual Living Scientists.
The next scientist in our series is Rachel Weller Roska. Rachel has been with Bio-Techne for 5 years at the R&D Systems site (and Bio-Techne Headquarters) in Minneapolis, MN. Rachel works in our Proteome Profiler Array Development Department as a Scientist...
It recently came to our attention, from this article, that only one in three Americans can name an actual living scientist. As a large biotechnology company, filled with talented and dedicated scientists, we think that is ridiculous. We want to introduce you to some of our staff who are, in fact, Actual Living Scientists.
The next scientist in our series is Martin Ramsden, PhD. Martin has been with Bio-Techne for 8 years at the R&D Systems site (and Bio-Techne Headquarters) in Minneapolis, MN. Martin works in our Commerical Development Department, which develops...
Bio-Techne scientists presented a poster at AAI 2017 demonstrating the effects that cell culture conditions can have on the phenotypic characterization of human M1 and M2a macrophages. This poster compared the expression of fifty macrophage cell surface markers, leading to the identification of twenty markers that were affected by culturing in the presence of fetal bovine serum (FBS), human serum, or StemXVivo® Serum-Free Dendritic Cell Base Media. Each condition was performed with and without polarizing stimuli.
It recently came to our attention, from this article, that only one in three Americans can name an actual living scientist. As a large biotechnology company, filled with talented and dedicated scientists, we think that is ridiculous. We want to introduce you to some of our staff who are, in fact, Actual Living Scientists.
The next scientist in our series is Kristin Jacobsen. Kristin just celebrated 6 years with Bio-Techne at the R&D Systems site (and Bio-Techne Headquarters) in Minneapolis, MN. Kristin not only works in Protein Development, she also recently completed her MBA at the University of...
