Human CD5 Antibody (205919) [Biotin]

R&D Systems | Catalog # FAB1636B

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2A Clone # 205919
View all CD5 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CD5
Arg25-Asn371
Accession # P06127

Specificity

Detects human CD5 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human CD5 Antibody (205919) [Biotin]

Detection of CD5 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

Detection of CD5 in Human Blood Lymphocytes by Flow Cytometry.

Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD5 Biotinylated Monoclonal Antibody (Catalog # FAB1636B, filled histogram) or isotype control antibody (Catalog # IC003B, open histogram), followed by Streptavidin-Phycoerythrin (Catalog # F0040). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CD5 Antibody (205919) [Biotin]

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood lymphocytes

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD5

CD5, also known as Leu-1, is a type I transmembrane protein belonging to the scavenger receptor cysteine-rich (SRCR) superfamily. It is expressed on thymocytes, T cells and the B1a subpopulation of B cells. CD5 binds the C-type lectin, CD72, and modulates signaling through the antigen receptors on T and B cells. CD5 has been shown to provide either positive or negative co-stimulatory signals depending on cell type to regulate immune responses.

References

  1. Ledbetter, J.A. et al. (1985) J. Immunol. 135:2331.
  2. Damle, N.K. et al. (1988) J. Immunol. 140:1753.

Alternate Names

CD5

Entrez Gene IDs

921 (Human); 12507 (Mouse)

Gene Symbol

CD5

UniProt

P06127

Additional CD5 Products

Product Documents for Human CD5 Antibody (205919) [Biotin]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CD5 Antibody (205919) [Biotin]

For research use only

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