Integrin alpha V/CD51 Antibody (24GB4430)

Name: Integrin alpha V/CD51 Antibody (24GB4430)
Brand: Novus Biologicals
SKU: NBP3-51643
Price: 499 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-51643

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Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB4430

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Product Specifications

Immunogen

Recombinant protein of human Integrin alpha V/CD51 (Uniprot: P06756)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Integrin alpha V/CD51 Antibody (24GB4430)

Immunocytochemistry/ Immunofluorescence: Integrin alpha V/CD51 Antibody (24GB4430)[NBP3-51643] -

Immunocytochemical staining of HepG2 cells with Integrin alpha V/CD51 antibody(1:1,000). Nuclei were stained blue with DAPI; Integrin alpha V/CD51 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 um.

Flow Cytometry: Integrin alpha V/CD51 Antibody (24GB4430)[NBP3-51643] -

Flow cytometric analysis of Integrin alpha V/CD51expression in HepG2 cells using Integrin alpha V/CD51 antibody (1:2,000). Green, isotype control; red, integrin subunit alpha V.

Western Blot: Integrin alpha V/CD51 Antibody (24GB4430)[NBP3-51643] -

Western blotting analysis using Integrin alpha V/CD51 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using NaQ(TM) ECL Substrate Kit.

Western Blot: Integrin alpha V/CD51 Antibody (24GB4430)[NBP3-51643] -

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Applications for Integrin alpha V/CD51 Antibody (24GB4430)

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

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Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

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Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Integrin alpha V/CD51

Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components.

Alternate Names

CD51, ITGAV, MSK8, Vitronectin Receptor alpha, VNRA

Gene Symbol

ITGAV

Additional Integrin alpha V/CD51 Products

Product Documents for Integrin alpha V/CD51 Antibody (24GB4430)

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Certificate of Analysis

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Product Specific Notices for Integrin alpha V/CD51 Antibody (24GB4430)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.