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Buffers, Chelators and Reagents Small Molecule
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Description: Artificial cerebrospinal fluid

Chemical Name: Artificial cerebrospinal fluid

Product Details
Citations (19)
Reviews (2)

Biological Activity

Artificial cerebrospinal fluid (aCSF) commonly used when sampling from brain interstitial fluid. Closely matches the electrolyte concentrations of CSF and is prepared from high purity water and analytical grade reagents. Microfiltered and sterile. Final ion concentrations (in mM): Na 150; K 3.0; Ca 1.4; Mg 0.8; P 1.0; Cl 155.

Technical Data

Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for ACSF

The citations listed below are publications that use Tocris products. Selected citations for ACSF include:

19 Citations: Showing 1 - 10

  1. Mitochondrial Dynamin-Related Protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing.
    Authors: Desmoulins Et al.
    Mol Metab  2019;20:166
  2. Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis.
    Authors: Hill Et al.
    Br.J.Pharmacol.  2018;175:3407
  3. Acute ghrelin changes food preference from a high-fat diet to chow during binge-like eating in rodents.
    Authors: Bake Et al.
    J Neuroendocrinol  2017;29
  4. Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and ins. Release Control.
    Authors: Ramírez Et al.
    Cell Metab  2017;25:1390
  5. Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight.
    Authors: Zhang Et al.
    Cell Metab  2017;25:1091
  6. SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.
    Authors: Mitroi Et al.
    Autophagy  2017;13:885
  7. Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism.
    Authors: Claflin Et al.
    J Clin Invest  2017;127:1414
  8. Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS
    Authors: Lam Et al.
    Neurology: Neuroimmunology & Neuroinflammation  2016;3:256
  9. The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.
    Authors: Kurland Et al.
    J Neuroinflammation  2016;13:130
  10. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.
    Authors: Suberbielle Et al.
    Front Pharmacol  2015;6:8897


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Reviews for ACSF

Average Rating: 4.5 (Based on 2 Reviews)

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Great for infusions into cortex!
By Christina Echagarruga on 01/04/2018
Species: Mouse

We use aCSF to infuse drugs into the brain. We usually dissolve the different drugs that we infuse in aCSF and then use aCSF infusions as a control

aCSF for in vivo application as solvent in brain infusion experiment in mice
By Anonymous on 07/17/2017
Species: Mouse

In vivo application as solvent in brain infusion experiment in mice.

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