Catalog Number: 3525
Chemical Name: Artificial cerebrospinal fluid
Biological Activity
Artificial cerebrospinal fluid (aCSF) commonly used when sampling from brain interstitial fluid. Closely matches the electrolyte concentrations of CSF and is prepared from high purity water and analytical grade reagents. Microfiltered and sterile. Final ion concentrations (in mM): Na 150; K 3.0; Ca 1.4; Mg 0.8; P 1.0; Cl 155.
Technical Data
  • Storage:
    Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease.
    Byun et al.
    PLoS One, 2012;7:e37917

The citations listed below are publications that use Tocris products. Selected citations for ACSF include:

8 Citations: Showing 1 - 8
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  1. Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS
    Authors: Lam Et al.
    Neurology: Neuroimmunology & Neuroinflammation 2016;3:256
  2. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.
    Authors: Suberbielle Et al.
    Front Pharmacol 2015;6:8897
  3. The depressor response to intracerebroventricular hypotonic saline is sensitive to TRPV4 antagonist RN1734.
    Authors: Feetham Et al.
    Electrophoresis 2015;6:83
  4. Increased Basolateral Amygdala Pyramidal Cell Excitability May Contribute to the Anxiogenic Phenotype Induced by Chronic Early-Life Stress.
    Authors: Rau Et al.
    Nat Commun 2015;35:9730
  5. Investigating local and long-range neuronal network dynamics by simultaneous optogenetics, reverse microdialysis and silicon probe recordings in vivo.
    Authors: Taylor Et al.
    J Neurosci 2014;235:83
  6. Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics.
    Authors: McCall Et al.
    Nat Protoc 2013;8:2413
  7. Detection of cerebral spinal fluid-associated chemokines in birth traumatized premature babies by chip-based immunoaffinity CE.
    Authors: Phillips and Wellner
    J Biol Chem 2013;34:1530
  8. Central 5-α reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats.
    Authors: Handa Et al.
    J Neurosci Methods 2013;1529:74
Average Rating: 4 (Based on 1 review)

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  Anonymous 07/17/2017

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