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Buffers, Chelators and Reagents Small Molecule
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Description: Artificial cerebrospinal fluid

Chemical Name: Artificial cerebrospinal fluid

Product Details
Citations (14)
Reviews (2)

Biological Activity

Artificial cerebrospinal fluid (aCSF) commonly used when sampling from brain interstitial fluid. Closely matches the electrolyte concentrations of CSF and is prepared from high purity water and analytical grade reagents. Microfiltered and sterile. Final ion concentrations (in mM): Na 150; K 3.0; Ca 1.4; Mg 0.8; P 1.0; Cl 155.

Technical Data

Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for ACSF

The citations listed below are publications that use Tocris products. Selected citations for ACSF include:

14 Citations: Showing 1 - 10

  1. Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis.
    Authors: Hill Et al.
    Br.J.Pharmacol.  2018;175:3407
  2. SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.
    Authors: Mitroi Et al.
    Autophagy  2017;13:885
  3. Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS
    Authors: Lam Et al.
    Neurology: Neuroimmunology & Neuroinflammation  2016;3:256
  4. The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.
    Authors: Kurland Et al.
    J Neuroinflammation  2016;13:130
  5. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.
    Authors: Suberbielle Et al.
    Front Pharmacol  2015;6:8897
  6. The depressor response to intracerebroventricular hypotonic saline is sensitive to TRPV4 antagonist RN1734.
    Authors: Feetham Et al.
    Electrophoresis  2015;6:83
  7. Increased Basolateral Amygdala Pyramidal Cell Excitability May Contribute to the Anxiogenic Phenotype Induced by Chronic Early-Life Stress.
    Authors: Rau Et al.
    Nat Commun  2015;35:9730
  8. Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity.
    Authors: Sartor Et al.
    J Neurosci  2015;35:15062
  9. Hypothalamic eIF2α signaling regulates food intake.
    Authors: Maurin Et al.
    Cell Rep  2014;6:438
  10. Investigating local and long-range neuronal network dynamics by simultaneous optogenetics, reverse microdialysis and silicon probe recordings in vivo.
    Authors: Taylor Et al.
    J Neurosci  2014;235:83


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Reviews for ACSF

Average Rating: 4.5 (Based on 2 Reviews)

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Great for infusions into cortex!
By Christina Echagarruga on 01/04/2018
Species: Mouse

We use aCSF to infuse drugs into the brain. We usually dissolve the different drugs that we infuse in aCSF and then use aCSF infusions as a control

aCSF for in vivo application as solvent in brain infusion experiment in mice
By Anonymous on 07/17/2017
Species: Mouse

In vivo application as solvent in brain infusion experiment in mice.

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