CD14 Antibody (CL1638) - BSA Free

Name: CD14 Antibody (CL1638) - BSA Free
Brand: Novus Biologicals
SKU: NBP2-34486
Price: 429 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-34486

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # CL1638

Format

BSA Free

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Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from D6RFL4, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Description

Novus Biologicals Mouse CD14 Antibody (CL1638) - BSA Free (NBP2-34486) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CD14 Antibody (CL1638) - BSA Free

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486]

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486] - Staining in human liver and pancreas tissues. Corresponding CD14 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486]

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486] - Staining of human liver shows moderate membranous positivity in Kupffer cells.

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486]

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486] - Staining of human tonsil shows moderate membranous positivity, mainly in germinal center cells.

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486]

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486] - Staining of human rectum shows moderate membranous positivity in lymphoid cells.

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486]

Immunohistochemistry-Paraffin: CD14 Antibody (CL1638) [NBP2-34486] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

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Applications for CD14 Antibody (CL1638) - BSA Free

Application

Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD14

CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils. The M5E2 antibody inhibits monocyte activation and cytokine production induced by LPS.

Alternate Names

CD14

Gene Symbol

CD14

UniProt

D6RFL4 (Human)

Additional CD14 Products

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Product Specific Notices for CD14 Antibody (CL1638) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.