CD14 Antibody (TUK4) - BSA Free

Name: CD14 Antibody (TUK4) - BSA Free
Brand: Novus Biologicals
SKU: NB100-62994
Price: 429 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-62994

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Product Documents

Clone TUK4 was used by HLDA to establish CD designation.

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Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG_2A Clone # TUK4

Format

BSA Free

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Product Specifications

Immunogen

Made to Human CD14

Reactivity Notes

Predicted cross-reactivities: Rabbit, Porcine, Feline, Cynomolgus monkey, Dog, Bovine, Llama, Mink, Goat, Sheep

Localization

Cell Membrane

Specificity

This product recognises the human CD14 cell surface antigen, expressed strongly by most peripheral blood monocytes and weakly on granulocytes. Clone Tuk4 has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner(6).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Scientific Data Images for CD14 Antibody (TUK4) - BSA Free

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood monocytes with Mouse anti Human CD14.

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] Staining of human peripheral blood monocytes with Mouse anti Human CD14

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood granulocytes with Mouse anti Human CD14.

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood monocytes probed with Mouse anti Human CD14.

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood monocytes with Mouse anti Human CD14.

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood monocytes with Mouse anti Human CD14.

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood monocytes with Mouse anti Human CD14.

Flow Cytometry: CD14 Antibody (TUK4) - BSA Free [NB100-62994]

Flow Cytometry: CD14 Antibody (11-248.2) [NB100-62994] - Staining of human peripheral blood monocytes with Mouse anti Human CD14.

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Applications for CD14 Antibody (TUK4) - BSA Free

Application

Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:50-1:200

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Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

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Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD14

CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Alternate Names

CD14

Entrez Gene IDs

929 (Human)

Gene Symbol

CD14

UniProt

P08571

Additional CD14 Products

Product Documents for CD14 Antibody (TUK4) - BSA Free

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Certificate of Analysis

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Product Specific Notices for CD14 Antibody (TUK4) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.