Catalog Number: 1952
Alternate Names: 3,3'-Dichlorobenzaldazine
Chemical Name: [(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde
Biological Activity
Allosteric ligand for the metabotropic glutamate receptor mGlu5; displays neutral modulation. Does not affect agonist-stimulated mGlu5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB (Cat. No. 1625) and DMeOB (Cat. No. 1953).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in ethanol with gentle warming and to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
    O'Brien et al.
    Mol.Pharmacol., 2003;64:731
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