R&D Systems supports ECM research with a full line of recombinant proteins and antibodies as well as Tocris Bioscience peptides and small molecules. Our immunoassay selection includes Quantikine® and DuoSet® ELISA kits, ELISpot kits, Luminex® assays, and Proteome Profiler™ antibody arrays. We also provide stem cell and cell culture products to support your research. Learn More.
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Recombinant Proteins
Quantikine® and DuoSet® ELISA Kits
Multi-analyte Assays
Luminex® High Performance Assays
Small Molecule Agonists and Antagonists
Extracellular Matrix Literature and Resources
Brochures and Product Guides
Cardiovascular Research Product Guide
Products for Chemokine Research
Products for Glycobiology Research
Signal Transduction Antibody Reference Guide
Posters
Atherosclerosis Disease Progression
Microenvironmental Regulation of Tumor Growth & Metastasis
References and Troubleshooting Guides
Articular Cartilage Extracellular Matrix Interactive Pathway
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions
Protocols/Troubleshooting Guides From Novus Biologicals®
Protocols/Troubleshooting Guides From R&D Systems®
Background
The extracellular matrix (ECM) surrounding blood and lymphatic vessels provides a physical support for the vessels and serves as a reservoir for chemotactic and growth factors. It is composed of fibrous proteins such as Collagens, Fibronectin, and Laminins as well as matricellular molecules such as Fibulins and Matrilins. Increased deposition of matrix components during disease and wound healing can lead to their abnormal accumulation and fibrosis.