Extracellular Matrix and Fibrosis Products

R&D Systems supports ECM research with a full line of recombinant proteins and antibodies as well as Tocris Bioscience peptides and small molecules. Our immunoassay selection includes Quantikine® and DuoSet® ELISA kits, ELISpot kits, Luminex® assays, and Proteome Profiler antibody arrays. We also provide stem cell and cell culture products to support your research. Learn More.

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Background

The extracellular matrix (ECM) surrounding blood and lymphatic vessels provides a physical support for the vessels and serves as a reservoir for chemotactic and growth factors. It is composed of fibrous proteins such as Collagens, Fibronectin, and Laminins as well as matricellular molecules such as Fibulins and Matrilins. Increased deposition of matrix components during disease and wound healing can lead to their abnormal accumulation and fibrosis.