Catalog Number: 4689
Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
Biological Activity
Inactive isomer of GSK J4; also cell permeable ester derivative of the inactive control, GSK J2.

Active Analog also available.

Technical Data
  • M.Wt:
    417.5
  • Formula:
    C24H27N5O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    1394854-51-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details of GSK J5, a cell permeable inactive isomer of GSK J1, please visit the GSK J1 probe summary on the SGC website.
Other Product-Specific Information:
Background References
  1. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
    Kruidenier et al.
    Nature, 2012;488:404
Citations:

The citations listed below are publications that use Tocris products. Selected citations for GSK J5 include:

1 Citations: Showing 1 - 1

  1. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.
    Authors: Carey Et al.
    Int J Nanomedicine 2015;518:413
Tocris Small Molecules
Description Application Cat# Citations Images  

GSK J4

4594 6  
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