Human CCR7 Biotinylated Antibody Summary
Accession # AAA58615
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of CCR7 in Human PBMCs by Flow Cytomtetry. Human peripheral blood mononuclear cells (PBMCs) were stained with PE-conjugated Mouse anti-Human CD4 Monoclonal Antibody (Catalog # FAB3791P) and either (A) Mouse anti-Human CCR7 Biotinylated Monoclonal Antibody (Catalog # FAB197B) or (B) Mouse IgG2A isotype control antibody (Catalog # IC003B) followed by APC-conjugated Streptavidin (Catalog # F0040). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
CCR7 (Chemokine Receptor 7; also CD197) is a 7 transmembrane (7TM) G protein-coupled chemokine receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine. CCL19 and CCL21 are constitutively expressed by high endothelial venule epithelial cells or fibroblastic reticular cells in secondary lymphoid organs. CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK cells, and B cells following inflammatory stimulation. Its expression enables the function of immune cell trafficking to and retention in regional lymph nodes for expansion of the adaptive immune response. Human CCR7 shares 87% amino acid sequence identity with mouse CCR7.
Citation for Human CCR7 Biotinylated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy
Authors: F Barrenäs, SG Hansen, L Law, C Driscoll, RR Green, E Smith, J Chang, I Golez, T Urion, X Peng, L Whitmore, D Newhouse, CM Hughes, D Morrow, KT Randall, AN Selseth, JC Ford, RM Gilbride, BE Randall, E Ainslie, K Oswald, R Shoemaker, R Fast, WJ Bosche, MK Axthelm, Y Fukazawa, GN Pavlakis, BK Felber, S Fourati, RP Sekaly, JD Lifson, J Komorowski, E Kosmider, D Shao, W Song, PT Edlefsen, LJ Picker, M Gale
PloS Pathogens, 2021;17(7):e1009278.
Species: Rhesus Macaque
Sample Types: Whole Cells
Applications: Flow Cytometry
No product specific FAQs exist for this product, however you mayView all Antibody FAQs
Supplemental Cell Selection Products
Supplemental ELISA Products
Reviews for Human CCR7 Biotinylated Antibody
There are currently no reviews for this product. Be the first to review Human CCR7 Biotinylated Antibody and earn rewards!
Have you used Human CCR7 Biotinylated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image