Human IGF-I/IGF-1 Quantikine ELISA Kit Summary
Product Summary
Precision
Serum-free Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean | 0.594 | 1.02 | 1.94 | 0.617 | 1.01 | 2.1 |
Standard Deviation | 0.026 | 0.046 | 0.077 | 0.038 | 0.06 | 0.12 |
CV% | 4.4 | 4.5 | 4 | 6.2 | 5.9 | 5.7 |
Recovery
The recovery of human IGF-1 spiked to three different levels throughout the range of the assay was evaluated. Samples were diluted prior to assay as described in the Sample Preparation section.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=4) | 93 | 88-97 |
Linearity
Data Examples
Product Datasheets
Preparation and Storage
Background: IGF-I/IGF-1
Insulin-like growth factor 1 (IGF-1, also known as somatomedin C) is a 7.6 kDa, 70 amino acid (aa) polypeptide with three internal disulfide bonds. The sequence of human IGF-1 is identical to that of bovine and porcine IGF-1, and is 70% identical to human IGF2. IGF-1 is a single-chain molecule with about 50% identity to the sequences of the A- and B-chains of human insulin.
Citations for Human IGF-I/IGF-1 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults
Authors: F Buckinx, LP Carvalho, V Marcangeli, M Dulac, G Hajj Boutr, G Gouspillou, P Gaudreau, P Noirez, M Aubertin-L
Exp. Gerontol., 2020;0(0):111036.
Species: Human
Sample Types: Serum
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Effect of anti-inflammatory treatment on systemic inflammation, immune function, and endometrial health in postpartum dairy cows
Authors: OB Pascottini, SJ Van Schynd, JFW Spricigo, MR Carvalho, B Mion, ES Ribeiro, SJ LeBlanc
Sci Rep, 2020;10(1):5236.
Species: Bovine
Sample Types: Serum
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Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study
Authors: L Van Dyck, I Vanhorebee, A Wilmer, A Schrijvers, I Derese, L Mebis, PJ Wouters, G Van den Be, J Gunst, MP Casaer
Crit Care, 2020;24(1):249.
Species: Human
Sample Types:
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Serum insulin-like growth factor-1 as a potential marker for MDD diagnosis, its clinical characteristics, and treatment efficacy validation: data from an open-label vortioxetine study
Authors: OA Levada, AS Troyan, IY Pinchuk
BMC Psychiatry, 2020;20(1):208.
Species: Human
Sample Types: Serum
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Vitamin D Deficiency Is Associated with Muscle Atrophy and Reduced Mitochondrial Function in Patients with Chronic Low Back Pain
Authors: KP Dzik, W Skrobot, KB Kaczor, DJ Flis, MJ Karnia, W Libionka, J Antosiewic, W Kloc, JJ Kaczor
Oxid Med Cell Longev, 2019;2019(0):6835341.
Species: Human
Sample Types: Serum
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Early-Life Cadmium Exposure and Bone-Related Biomarkers: A Longitudinal Study in Children
Authors: A Malin Igra, M Vahter, R Raqib, M Kippler
Environ. Health Perspect., 2019;127(3):37003.
Species: Human
Sample Types: Plasma
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Redifferentiation of Articular Chondrocytes by Hyperacute Serum and Platelet Rich Plasma in Collagen Type I Hydrogels
Authors: V Jeyakumar, E Niculescu-, C Bauer, Z Lacza, S Nehrer
Int J Mol Sci, 2019;20(2):.
Species: Human
Sample Types: Cell Culture Supernates
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Serum concentrations of IGF-I/IGF-II as biomarkers of alcohol damage during foetal development and diagnostic markers of Foetal Alcohol Syndrome
Authors: V Andreu-Fer, A Bastons-Co, E Navarro-Ta, S Sailer, O Garcia-Alg
Sci Rep, 2019;9(1):1562.
Species: Human
Sample Types: Serum
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Hypoallergenic and anti-inflammatory feeds in children with complicated severe acute malnutrition: an open randomised controlled 3-arm intervention trial in Malawi
Authors: RH Bartels, E Chimwezi, V Watson, L Pei, I Potani, B Allubha, K Chidzalo, D Wang, Q Dube, M Mallewa, A Allen, RHJ Bandsma, WP Voskuijl, SJ Allen
Sci Rep, 2019;9(1):2304.
Species: Human
Sample Types: Plasma
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Ginsenoside Rg1 Accelerates Paracrine Activity and Adipogenic Differentiation of Human Breast Adipose-Derived Stem Cells in a Dose-Dependent Manner In Vitro
Authors: ZJ Liang, X Lu, DD Zhu, XL Yi, FX Wu, N He, C Tang, CY Wei, HM Li
Cell Transplant, 2019;0(0):9636897198256.
Species: Human
Sample Types: Cell Culture Supernates
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Impact of HIV-1 infection on the IGF-1 axis and angiogenic factors in pregnant Cameroonian women receiving antiretroviral therapy
Authors: LF Esemu, EK Yuosembom, R Fang, S Rasay, BAY Fodjo, JT Nguasong, W Kidima, GL Ekali, JJ Chen, L Ndhlovu, JD Bigoga, DW Taylor, RGF Leke, A Babakhanya
PLoS ONE, 2019;14(5):e0215825.
Species: Human
Sample Types: Plasma
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Investigating Stress Response during Vaginal Delivery and Elective Cesarean Section through Assessment of Levels of Cortisol, Interleukin 6 (IL-6), Growth Hormone (GH) and Insulin-Like Growth Factor 1 (IGF-1)
Authors: N Kiriakopou, S Grigoriadi, E Maziotis, A Philippou, A Rapani, P Giannelou, P Tsioulou, K Sfakianoud, A Kontogeorg, P Bakas, G Mastorakos, M Koutsilier, M Simopoulou
J Clin Med, 2019;8(8):.
Species: Human
Sample Types: Serum
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Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-? and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells
Authors: S Morscheid, A Rey-Rico, G Schmitt, H Madry, M Cucchiarin, JK Venkatesan
Int J Mol Sci, 2019;20(10):.
Species: Human
Sample Types: Cell Culture Supernates
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A Potato Peel Extract Stimulates Type I Collagen Synthesis via Akt and ERK Signaling in Normal Human Dermal Fibroblasts
Authors: M Suto, H Masutomi, K Ishihara, H Masaki
Biol. Pharm. Bull., 2019;42(9):1510-1516.
Species: Human
Sample Types: Cell Culture Supernates
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An Autocrine IL-6/IGF-1R Loop Mediates EMT and Promotes Tumor Growth in Non-small Cell Lung Cancer
Authors: X Zheng, G Lu, Y Yao, W Gu
Int. J. Biol. Sci., 2019;15(9):1882-1891.
Species: Human
Sample Types: Cell Culture Supernates
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Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra-SRS, with autocrine IGF-1R activation and metastatic potential to the lungs
Authors: S Nakai, S Yamada, H Outani, T Nakai, N Yasuda, H Mae, Y Imura, T Wakamatsu, H Tamiya, T Tanaka, K Hamada, A Tani, A Myoui, N Araki, T Ueda, H Yoshikawa, S Takenaka, N Naka
Sci Rep, 2019;9(1):15812.
Species: Human
Sample Types: Cell Culture Supernates
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Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients
Authors: T Nakajima, I Shibasaki, T Sawaguchi, A Haruyama, H Kaneda, T Nakajima, T Hasegawa, T Arikawa, S Obi, M Sakuma, H Ogawa, S Toyoda, F Nakamura, S Abe, H Fukuda, T Inoue
J Clin Med, 2019;8(10):.
Species: Human
Sample Types: Serum
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Human cardiac progenitor cell activation and regeneration mechanisms: exploring a novel myocardial ischemia/reperfusion in vitro model
Authors: MJ Sebastião, M Serra, R Pereira, I Palacios, P Gomes-Alve, PM Alves
Stem Cell Res Ther, 2019;10(1):77.
Species: Human
Sample Types: Cell Culture Supernates
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Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches
Authors: C Saury, A Lardenois, C Schleder, I Leroux, B Lieubeau, L David, M Charrier, L Guével, S Viau, B Delorme, K Rouger
Stem Cell Res Ther, 2018;9(1):128.
Species: Human
Sample Types: Cell Culture Supernates
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Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Authors: DH Bak, MJ Choi, SR Kim, BC Lee, JM Kim, ES Jeon, W Oh, ES Lim, BC Park, MJ Kim, J Na, BJ Kim
Korean J. Physiol. Pharmacol., 2018;22(5):555-566.
Species: Human
Sample Types: Cell Culture Supernates
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The effect of autologous platelet rich plasma on tenocytes of the human rotator cuff
Authors: S Pauly, F Klatte-Sch, K Stahnke, M Scheibel, B Wildemann
BMC Musculoskelet Disord, 2018;19(1):422.
Species: Human
Sample Types: Plasma
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Characterization of induced pluripotent stem cell-derived megakaryocyte lysates for potential regenerative applications
Authors: A Baigger, D Eicke, Y Yuzefovych, D Pogozhykh, R Blasczyk, C Figueiredo
J. Cell. Mol. Med., 2018;0(0):.
Species: Human
Sample Types: Cell Lysates
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Relative Bioavailability of a Single 4-mg Dose of Somatropin Administered by Subcutaneous Injection or by Needle-free Device and Coadministered With the Growth Hormone Inhibitor Octreotide Acetate in Healthy Adult Subjects
Authors: DB Brimhall, N Petri, P D'Angelo
Clin Ther, 2018;0(0):.
Species: Human
Sample Types: Serum
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Physical Exercise and Spatial Training: A Longitudinal Study of Effects on Cognition, Growth Factors, and Hippocampal Plasticity
Authors: L Woost, PL Bazin, M Taubert, R Trampel, CL Tardif, A Garthe, G Kempermann, U Renner, G Stalla, DVM Ott, V Rjosk, H Obrig, A Villringer, E Roggenhofe, TA Klein
Sci Rep, 2018;8(1):4239.
Species: Human
Sample Types: Serum
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The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people
Authors: M Krause, D Crognale, K Cogan, S Contarelli, B Egan, P Newsholme, G De Vito
Exp. Gerontol., 2018;115(0):104-113.
Species: Human
Sample Types: Plasma
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Differences in biochemical markers between Heart-transplanted and Left Ventricular Assist Device implanted patients, during cardiac rehabilitation
Authors: V Racca, P Castiglion, C Panzarino, M Saresella, I Marventano, A Verde, F Oliva, M Ferratini
Sci Rep, 2018;8(1):10816.
Species: Human
Sample Types: Serum
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A 2-Week Specific Volleyball Training Supported by the Whole Body Cryostimulation Protocol Induced an Increase of Growth Factors and Counteracted Deterioration of Physical Performance
Authors: J Jaworska, K Micielska, M Koz?owska, K Wnorowski, J Skrobecki, L Radzimi?sk, A Babi?ska, E Rodziewicz, G Lombardi, E Ziemann
Front Physiol, 2018;9(0):1711.
Species: Human
Sample Types: Serum
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Relationships of Age and Sex with Cytokine Content and Distribution in Human Platelet Fibrin Gels
Authors: MY Bai, MH Chuang, MF Lin, SL Tang, CC Wong, WP Chan
Sci Rep, 2018;8(1):10642.
Species: Rabbit
Sample Types: Platelet Rich Fibrin
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1H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures
Authors: F Agostini, M Ruzza, D Corpillo, L Biondi, E Acquadro, B Canepa, A Viale, M Battiston, F Serra, S Aime, M Mazzucato
PLoS ONE, 2018;13(9):e0203048.
Species: Human
Sample Types: Cell Culture Supernates
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Impact of Chronic Neonatal Intermittent Hypoxia on Severity of Retinal Damage in a Rat Model of Oxygen-Induced Retinopathy
Authors: KD Beharry, CL Cai, T Ahmad, S Guzel, GB Valencia, JV Aranda
J Nat Sci, 2018;4(3):.
Species: Rat
Sample Types: Tissue Homogenates
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The levels of pro-fibrotic cytokines in pulmonary tuberculosis with minimal and extensive lesions
Authors: T Astuti, IN Chozin, NS Damayanti, D Nugrahenny
Lung India, 2018;35(3):204-208.
Species: Human
Sample Types: Plasma
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l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function
Authors: AK Sawicka, D Hartmane, P Lipinska, E Wojtowicz, W Lysiak-Szy, RA Olek
Nutrients, 2018;10(2):.
Species: Human
Sample Types: Serum
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Pre-weaning injections of bovine somatotropin enhanced reproductive performance of Bos indicus-influenced replacement beef heifers
Authors: MB Piccolo, JD Arthington, GM Silva, GC Lamb, RF Cooke, P Moriel
J. Anim. Sci., 2018;0(0):.
Species: Bovine
Sample Types: Plasma
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Central Infusion of IGF-1 Increases Hippocampal Neurogenesis and Improves Neurobehavioral Function following Traumatic Brain Injury
Authors: SW Carlson, KE Saatman
J. Neurotrauma, 2018;0(0):.
Species: Mouse
Sample Types: Serum
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Shifting the IGF-axis: An age-related decline in human tear IGF-1 correlates with clinical signs of dry eye
Authors: R Patel, M Zhu, DM Robertson
Growth Horm. IGF Res., 2018;0(0):.
Species: Human
Sample Types: Tears
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Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway
Authors: W Zhou, J Wang, Q Qi, Z Feng, B Huang, A Chen, D Zhang, W Li, Q Zhang, R Bjerkvig, X Li, J Wang
Cancer Med, 2018;0(0):.
Species: Human
Sample Types: Cell Cultue Supernates
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Validation of insulin-like growth factor-1 as a prognostic parameter in patients with hepatocellular carcinoma in a European cohort
Authors: Y Huber, F Bierling, C Labenz, S Koch, I Schmidtman, R Kloeckner, S Schotten, T Huber, H Lang, MA Woerns, PR Galle, A Weinmann, J Weinmann-M
BMC Cancer, 2018;18(1):774.
Species: Human
Sample Types: Serum
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Effects of treatment of preweaning dairy calves with recombinant bovine somatotropin on immune responses and somatotropic axis
Authors: AL Belli, RB Reis, A Veronese, R Moreira, K Flanagan, J Driver, CD Nelson, JA Clapper, MA Ballou, KC Jeong, RC Chebel
J. Dairy Sci., 2018;0(0):.
Species: Bovine
Sample Types: Serum
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Evaluation of Coated Steroidal Implants Containing Trenbolone Acetate and Estradiol-17? on Live Performance, Carcass Traits, and Sera Metabolites in Finishing Steers
Authors: ZK Smith, AJ Thompson, JP Hutcheson, WT Nichols, BJ Johnson
J. Anim. Sci., 2018;0(0):.
Species: Bovine
Sample Types: Serum
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Metformin inhibits the proliferation of benign prostatic epithelial cells
Authors: Z Wang, X Xiao, R Ge, J Li, CW Johnson, C Rassoulian, AF Olumi
PLoS ONE, 2017;12(3):e0173335.
Species: Human
Sample Types: Cell Culture Supernates
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Effect of Physical Activity on Cognitive Development: Protocol for a 15-Year Longitudinal Follow-Up Study
Authors: G Zhao, M Quan, L Su, H Zhang, J Zhang, J Zhang, H Fang, ZB Cao, Z Zhu, Z Niu, R Wang, P Chen
Biomed Res Int, 2017;2017(0):8568459.
Species: Human
Sample Types: Plasma
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Serum IGF-1 is associated with cognitive functions in early, drug-na�ve Parkinson's disease
Authors: M Picillo, R Pivonello, G Santangelo, C Pivonello, R Savastano, R Auriemma, M Amboni, S Scannapiec, A Pierro, A Colao, P Barone, MT Pellecchia
PLoS ONE, 2017;12(10):e0186508.
Species: Human
Sample Types: Serum
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Evaluation of autologous skeletal muscle-derived factors for regenerative medicine applications
Authors: M Yoshikawa, T Nakasa, M Ishikawa, N Adachi, M Ochi
Bone Joint Res, 2017;6(5):277-283.
Species: Human
Sample Types: Tissue Homogenates
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Five-weekly S-1 plus cisplatin therapy combined with trastuzumab therapy in HER2-positive gastric cancer: a phase II trial and biomarker study (WJOG7212G)
Authors: Y Miura, Y Sukawa, S Hironaka, M Mori, K Nishikawa, S Tokunaga, H Okuda, T Sakamoto, K Taku, K Nishikawa, T Moriwaki, Y Negoro, Y Kimura, K Uchino, K Shinozaki, H Shinozaki, N Musha, H Yoshiyama, T Tsuda, Y Miyata, N Sugimoto, T Shirakawa, M Ito, K Yonesaka, K Yoshimura, N Boku, K Nosho, T Takano, I Hyodo
Gastric Cancer, 2017;0(0):.
Species: Human
Sample Types: Serum
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A phase II randomized, double-blind, presurgical trial of Polyphenon E in bladder cancer patients to evaluate pharmacodynamics and bladder tissue biomarkers
Authors: JR Gee, DR Saltzstein, K Kim, JM Kolesar, W Huang, TC Havighurst, BW Wollmer, J Stublaski, T Downs, H Mukhtar, M House, HL Parnes, HH Bailey
Cancer Prev Res (Phila), 2017;0(0):.
Species: Human
Sample Types: Serum
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Hypoxic preconditioning of human cardiosphere-derived cell sheets enhances cellular functions via activation of the PI3K/Akt/mTOR/HIF-1? pathway
Authors: Y Tanaka, T Hosoyama, A Mikamo, H Kurazumi, A Nishimoto, K Ueno, B Shirasawa, K Hamano
Am J Transl Res, 2017;9(2):664-673.
Species: Human
Sample Types: Cell Culture Supernates
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Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes
Authors: J Frisch, P Orth, A Rey-Rico, JK Venkatesan, G Schmitt, H Madry, D Kohn, M Cucchiarin
J. Cell. Mol. Med., 2017;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Effects of transdermal testosterone gel or an aromatase inhibitor on serum concentration and pulsatility of growth hormone in older men with age-related low testosterone
Authors: JP Dias, JD Veldhuis, O Carlson, M Shardell, CW Chia, D Melvin, JM Egan, S Basaria
Metab. Clin. Exp., 2017;69(0):143-147.
Species: Human
Sample Types: Serum
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Relationships of insulin-like growth factor-1, its binding proteins, and cardiometabolic risk in hypertensive perimenopausal women
Authors: A Olszanecka, A Dragan, K Kawecka-Ja, D Fedak, D Czarnecka
Metab. Clin. Exp., 2017;69(0):96-106.
Species: Human
Sample Types: Plasma
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Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
Oxid Med Cell Longev, 2017;2017(0):3937842.
Species: Human
Sample Types: Plasma
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Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age
Authors: Francesca Pirini
Int J Environ Health Res, 2017;27(1):52-67.
Species: Human
Sample Types: Serum
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The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro
Authors: M Bernardi, F Agostini, K Chieregato, E Amati, C Durante, M Rassu, M Ruggeri, S Sella, E Lombardi, M Mazzucato, G Astori
J Transl Med, 2017;15(1):90.
Species: Human
Sample Types: Cell Lysates
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Umbilical cord extracts improve diabetic abnormalities in bone marrow-derived mesenchymal stem cells and increase their therapeutic effects on diabetic nephropathy
Authors: K Nagaishi, Y Mizue, T Chikenji, M Otani, M Nakano, Y Saijo, H Tsuchida, S Ishioka, A Nishikawa, T Saito, M Fujimiya
Sci Rep, 2017;7(1):8484.
Species: Human
Sample Types: Cell Culture Supernates
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Temporal changes in liver tissue metabolome of lambs fed low-quality roughage
Authors: W Xu, N Okayama, A Iwasawa, M Yayota
Anim. Sci. J., 2017;0(0):.
Species: Ovine
Sample Types: Serum
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Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems
Authors: P Gentile, JP Cole, MA Cole, S Garcovich, A Bielli, MG Scioli, A Orlandi, C Insalaco, V Cervelli
Int J Mol Sci, 2017;18(2):.
Species: Human
Sample Types: Plasma
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Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells
Authors: W Katagiri, T Kawai, M Osugi, Y Sugimura-W, K Sakaguchi, T Kojima, T Kobayashi
Maxillofac Plast Reconstr Surg, 2017;39(1):8.
Species: Human
Sample Types: Cell Culture Supernates
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Randomized Trial Testing the Effects of Eating Frequency on Two Hormonal Biomarkers of Metabolism and Energy Balance
Authors: Martine M Perrigue
Nutr Cancer, 2016;0(0):1-8.
Species: Human
Sample Types: Plasma
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Impact of Hyperglycemia and Low Oxygen Tension on Adipose-Derived Stem Cells Compared with Dermal Fibroblasts and Keratinocytes: Importance for Wound Healing in Type 2 Diabetes
PLoS ONE, 2016;11(12):e0168058.
Species: Human
Sample Types: Cell Culture Supernates
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Biological effects of plasma rich in growth factors (PRGF) on human endometrial fibroblasts
Authors: Gorka Orive
Eur. J. Obstet. Gynecol. Reprod. Biol., 2016;206(0):125-130.
Species: Human
Sample Types: Plasma
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Genetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population
Sci Rep, 2016;6(0):39014.
Species: Human
Sample Types: Serum
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Overcoming the bottleneck of platelet lysate supply in large-scale clinical expansion of adipose-derived stem cells: A comparison of fresh versus three types of platelet lysates from outdated buffy coat-derived platelet concentrates
Authors: Anne Fischer-Ni
Cytotherapy, 2016;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Elevations in growth hormone and glucagon-like peptide-2 levels on admission are associated with increased mortality in trauma patients.
Authors: Matthew P Rowan, Darrick J Beckman, Julie A Rizzo, Claire L Isbell, Christopher E White, Stephen M Cohn, Kevin K Chung
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2016;0(0):1757-7241.
Species: Human
Sample Types: Serum
Applications: ELISA Capture -
An adverse immune-endocrine profile in patients with tuberculosis and type 2 diabetes
Authors: O Bottasso
Tuberculosis (Edinb), 2016;101(0):95-101.
Species: Human
Sample Types: Plasma
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The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells
Nat Commun, 2016;7(0):12961.
Species: Human
Sample Types: Cell Culture Supernates
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IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma
Authors: Matthew N Svalina
Sci Rep, 2016;6(0):27012.
Species: Human
Sample Types: CSF
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Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia
Stem Cell Res Ther, 2016;7(1):128.
Species: Human
Sample Types: Cell Culture Supernates
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A preliminary study of pamidronic acid downregulation of angiogenic factors IGF-1/PECAM-1 expression in circulating level in bone metastatic breast cancer patients
Authors: Zeng Wang
Onco Targets Ther, 2016;9(0):3147-52.
Species: Human
Sample Types: Serum
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High glycemic index diet in PCOS patients. The analysis of IGF I and TNF-? pathways in metabolic disorders
Authors: M Szczuko
Med. Hypotheses, 2016;96(0):42-47.
Species: Human
Sample Types: Plasma
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Phase IIa, randomized placebo-controlled trial of single high dose cholecalciferol (vitamin D3) and daily Genistein (G-2535) versus double placebo in men with early stage prostate cancer undergoing prostatectomy
Authors: Howard H Bailey
Am J Clin Exp Urol, 2016;4(2):17-27.
Species: Human
Sample Types: Serum
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Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved
Authors: D Dauwe, B Pelacho, A Wibowo, AS Walravens, K Verdonck, H Gillijns, E Caluwe, P Pokreisz, N van Gastel, G Carmeliet, M Depypere, F Maes, N Vanden Dri, W Droogne, J Van Cleemp, J Vanhaecke, F Prosper, C Verfaillie, A Luttun, S Janssens
J Am Heart Assoc, 2016;5(4):.
Species: Human
Sample Types: Cell Culture Supernates
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Implantation of rAAV5-IGF-I transduced autologous chondrocytes improves cartilage repair in full-thickness defects in the equine model.
Authors: Ortved K, Begum L, Mohammed H, Nixon A
Mol Ther, 2015;23(2):363-73.
Species: Equine
Sample Types: Synovial Fluid
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LMP1 promotes expression of insulin-like growth factor 1 (IGF1) to selectively activate IGF1 receptor and drive cell proliferation.
Authors: Tworkoski K, Raab-Traub N
J Virol, 2015;89(5):2590-602.
Species: Human
Sample Types: Cell Culture Supernates
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Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I
Authors: Magali Cucchiarin
Tissue Eng Part A, 2015;21(17):2460-71.
Species: Human
Sample Types: Cell Culture Supernates
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Effects of exercise and milk fat globule membrane (MFGM) supplementation on body composition, physical function, and hematological parameters in community-dwelling frail Japanese women: a randomized double blind, placebo-controlled, follow-up trial.
Authors: Kim H, Suzuki T, Kim M, Kojima N, Ota N, Shimotoyodome A, Hase T, Hosoi E, Yoshida H
PLoS ONE, 2015;10(2):e0116256.
Species: Human
Sample Types: Serum
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A randomized phase II presurgical trial of transdermal 4-hydroxytamoxifen gel versus oral tamoxifen in women with ductal carcinoma in situ of the breast.
Authors: Lee O, Page K, Ivancic D, Helenowski I, Parini V, Sullivan M, Margenthaler J, Chatterton R, Jovanovic B, Dunn B, Heckman-Stoddard B, Foster K, Muzzio M, Shklovskaya J, Skripkauskas S, Kulesza P, Green D, Hansen N, Bethke K, Jeruss J, Bergan R, Khan S
Clin Cancer Res, 2014;20(14):3672-82.
Species: Human
Sample Types: Plasma
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Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo.
Authors: Cucchiarini M, Madry H
Gene Ther, 2014;21(9):811-9.
Species: Human
Sample Types: Cell Culture Supernates
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Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis.
Authors: Ho I, Toh H, Ng W, Teo Y, Guo C, Hui K, Lam P
Stem Cells, 2013;31(1):146-55.
Species: Human
Sample Types: Tissue Homogenates
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Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy.
Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
Cytokine, 2013;61(3):755-8.
Species: Human
Sample Types: Serum
-
Functional and differential proteomic analyses to identify platelet derived factors affecting ex vivo expansion of mesenchymal stromal cells.
Authors: Kinzebach S, Dietz L, Kluter H, Thierse H, Bieback K
BMC Cell Biol, 2013;14(0):48.
Species: Human
Sample Types: Cell Culture Supernates
-
Arsenic exposure affects plasma insulin-like growth factor 1 (IGF-1) in children in rural Bangladesh.
Authors: Ahmed S, Rekha R, Ahsan K, Doi M, Grander M, Roy A, Ekstrom E, Wagatsuma Y, Vahter M, Raqib R
PLoS ONE, 2013;8(11):e81530.
Species: Human
Sample Types: Plasma
-
Maternal and fetal placental growth hormone and IGF axis in type 1 diabetic pregnancy.
Authors: Higgins MF, Russell NE, Crossey PA, Nyhan KC, Brazil DP, McAuliffe FM
PLoS ONE, 2012;7(2):e29164.
Species: Human
Sample Types: Plasma
-
Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis.
Authors: Weimer A, Madry H, Venkatesan JK
Mol. Med., 2012;18(1):346-58.
Species: Human
Sample Types: Cell Culture Supernates
-
The stature of boys is inversely correlated to the levels of their sertoli cell hormones: do the testes restrain the maturation of boys?
Authors: Morgan K, Dennis NA, Ruffman T, Bilkey DK, McLennan IS
PLoS ONE, 2011;6(6):e20533.
Species: Human
Sample Types: Serum
-
Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.
Authors: Rauch C, Feifel E, Amann EM, Spotl HP, Schennach H, Pfaller W, Gstraunthaler G
ALTEX, 2011;28(4):305-16.
Species: Human
Sample Types: Cell Lysates
-
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
Authors: Li TS, Cheng K, Malliaras K, Matsushita N, Sun B, Marban L, Zhang Y, Marban E
Cardiovasc. Res., 2011;89(1):157-65.
Species: Human
Sample Types: Cell Culture Supernates
-
Prognostic significance of angiogenic factors in uterine cervical cancer.
Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2589-95.
Species: Human
Sample Types: Serum
-
Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
Obesity (Silver Spring), 2011;19(11):2130-6.
Species: Human
Sample Types: Plasma
-
Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer.
Authors: Volkova E, Willis JA, Wells JE, Robinson BA, Dachs GU, Currie MJ
Br. J. Cancer, 2011;104(1):51-9.
Species: Human
Sample Types: Serum
-
Abnormalities in metalloproteinase pathways and IGF-I axis: a link between birth weight, hypertension, and vascular damage in childhood.
Authors: Sesso R, Franco MC
Am. J. Hypertens., 2010;23(1):6-11.
Species: Human
Sample Types: Plasma
-
Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells.
Authors: Eckstein N, Servan K, Hildebrandt B, Politz A, von Jonquieres G, Wolf-Kummeth S, Napierski I, Hamacher A, Kassack MU, Budczies J, Beier M, Dietel M, Royer-Pokora B, Denkert C, Royer HD
Cancer Res., 2009;69(7):2996-3003.
Species: Human
Sample Types: Cell Culture Supernates
-
Insulin-like growth factor-1 and neurotrophin-3 gene therapy prevents motor decline in an X-linked adrenoleukodystrophy mouse model.
Authors: Mastroeni R, Bensadoun JC, Charvin D, Aebischer P, Pujol A, Raoul C
Ann. Neurol., 2009;66(1):117-22.
Species: Human
Sample Types: CSF
-
Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008;36(8):1035-46.
Species: Human
Sample Types: Cell Culture Supernates
-
Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis.
Authors: Pulichino AM, Wang IM, Caron A, Mortimer J, Auger A, Boie Y, Elias JA, Kartono A, Xu L, Menetski J, Sayegh CE
Am. J. Respir. Cell Mol. Biol., 2008;39(3):324-36.
Species: Human
Sample Types: BALF
-
Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance.
Authors: Ashare A, Nymon AB, Doerschug KC, Morrison JM, Monick MM, Hunninghake GW
Am. J. Respir. Crit. Care Med., 2008;178(2):149-57.
Species: Human
Sample Types: Serum
-
cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo.
Authors: Siddappa R, Martens A, Doorn J, Leusink A, Olivo C, Licht R, van Rijn L, Gaspar C, Fodde R, Janssen F, van Blitterswijk C, de Boer J
Proc. Natl. Acad. Sci. U.S.A., 2008;105(20):7281-6.
Species: Human
Sample Types: Cell Culture Supernates
-
Peripheral elevation of IGF-1 fails to alter Abeta clearance in multiple in vivo models.
Authors: Lanz TA, Salatto CT, Semproni AR, Marconi M, Brown TM, Richter KE, Schmidt K, Nelson FR, Schachter JB
Biochem. Pharmacol., 2007;75(5):1093-103.
Species: Canine
Sample Types: Plasma
-
The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
Fertil. Steril., 2007;90(1):60-4.
Species: Human
Sample Types: Follicular Fluid
-
Serum concentrations of insulin-like growth factor-I (igf-I) as a marker of liver fibrosis in patients with chronic hepatitis C.
Authors: Lorenzo-Zuniga V, Bartoli R, Masnou H, Montoliu S, Morillas RM, Planas R
Dig. Dis. Sci., 2007;52(11):3245-50.
Species: Human
Sample Types: Serum
-
Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy.
Authors: Yin D, Vreeland F, Schaaf LJ, Millham R, Duncan BA, Sharma A
Clin. Cancer Res., 2007;13(3):1000-9.
Species: Human
Sample Types: Plasma
-
Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
Authors: Doucet M, Russell AP, Leger B, Debigare R, Joanisse DR, Caron MA, LeBlanc P, Maltais F
Am. J. Respir. Crit. Care Med., 2007;176(3):261-9.
Species: Human
Sample Types: Plasma
-
Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) in IVF patients with polycystic ovary syndrome: correlations with outcome.
Authors: Schoyer KD, Liu HC, Witkin S, Rosenwaks Z, Spandorfer SD
Fertil. Steril., 2007;88(1):139-44.
Species: Human
Sample Types: Serum
-
Insulin-like growth factor-II (IGF-II), IGF-binding protein-3 (IGFBP-3), and IGFBP-4 in follicular fluid are associated with oocyte maturation and embryo development.
Authors: Wang TH, Chang CL, Wu HM, Chiu YM, Chen CK, Wang HS
Fertil. Steril., 2006;86(5):1392-401.
Species: Human
Sample Types: Follicular Fluid
-
Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation.
Authors: Herrmann S, Green J, Weber T, Scharfenberger A
Bone, 2006;39(5):1156-63.
Species: Human
Sample Types: Tissue Homogenates
-
Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
Glia, 2006;53(8):845-57.
Species: Human
Sample Types: Cell Culture Supernates
-
Growth hormone-induced stimulation of multilineage human hematopoiesis.
Authors: Hanley MB, Napolitano LA, McCune JM
Stem Cells, 2005;23(8):1170-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Insulin growth factor-1 protects against excitotoxicity in the rat striatum.
Authors: Escartin C, Boyer F, Bemelmans AP, Hantraye P, Brouillet E
Neuroreport, 2004;15(14):2251-4.
Species: Human
Sample Types: Recombinant Protein
-
Dose response of bone mass to dietary arachidonic acid in piglets fed cow milk-based formula.
Authors: Blanaru JL, Kohut JR, Fitzpatrick-Wong SC, Weiler HA
Am. J. Clin. Nutr., 2004;79(1):139-47.
Species: Porcine
Sample Types: Plasma
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