Human IkB-epsilon Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB4300R Datasheet / COA / SDS

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FAB4300R-100UG

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All IkB-epsilon Antibodies

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Human IkB-epsilon Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects endogenous human and mouse IkB-epsilon in Western blots.

Source

Monoclonal Mouse IgG2b Clone # 418515

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human IkB-Îµ
Ser64-Asp423
Accession # Q96F31

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IkB-epsilon

NF kappa B inhibitor epsilon (IkB epsilon ) inhibits the NF kappa B complex by binding and sequestering it in the cytoplasm. Upon stimulation, IkB epsilon is phosphorylated on serine residues marking it for degradation by the ubiquitin pathway. Following IkB epsilon degradation, the NF kappa B complex is able to translocate to the nucleus and activate transcription.

Long Name

I-kappa-B-epsilon

Entrez Gene IDs

4794 (Human); 18037 (Mouse)

Alternate Names

epsilon; ikappaBepsilon; I-kappa-B-epsilon; IkB-E; IKBENF-kappa-B inhibitor epsilon; IkBepsilon; IkB-epsilon; NF-kappa-BIE; NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor