Human LRP-1 APC-conjugated Antibody

Name: Human LRP-1 APC-conjugated Antibody
Brand: R&D Systems
SKU: FAB6360A

Catalog #: FAB6360A
1 Citation Datasheet / COA / SDS

Newer Version Available: MAB6360

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Discontinued Product

FAB6360A has been discontinued and is replaced by MAB6360.

Detection of LRP‑1 in HEK293 Human Cell Line by Flow Cytometry.

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All LRP-1 Antibodies

Product Details

Citations (1)

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Human LRP-1 APC-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human LRP-1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) LRP‑1 clusters 2, 3, or 4, rhLRP‑4, rhLRP-5, rhLRP-5 intracellular domain, rhLRP-6, rhLRP-6 intracellular domain, or rhLRPAP is observed.

Source

Monoclonal Mouse IgG_2B Clone # 545503

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant human LRP-1
Gln4449-ala4544
Accession # Q07954

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of LRP‑1 in HEK293 Human Cell Line by Flow Cytometry. HEK293 human embryonic kidney cell line was stained with Mouse Anti-Human LRP-1 APC-conjugated Monoclonal Antibody (Catalog # FAB6360A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: LRP-1

LDL Receptor related Protein 1 (LRP-1), also known as CD91 and alpha 2-macroglobulin receptor, is a type I membrane protein in the LDL receptor superfamily. It is expressed on neurons, hepatocytes, adipocytes, vascular smooth muscle cells, fibroblasts, keratinocytes, macrophages, and megakaryocytes.

Long Name

LDL Receptor-related Protein 1

Entrez Gene IDs

4035 (Human)

Alternate Names

A2MR; Alpha-2-Macroglobulin Receptor; APOER; Apolipoprotein E receptor; APR; CD91 antigen; CD91; EC 1.1.1.94; EC 3.4.21.9; IGFBP3R; low density lipoprotein receptor-related protein 1; LRP; LRP-1; LRP1A; prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human LRP-1 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages
Authors: K Schubert, LE Collins, P Green, H Nagase, L Troeberg
J. Immunol., 2019-01-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry