Human LRRC4 Antibody

Catalog # Availability Size / Price Qty
LRRC4 in Human Brain.
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Product Details
Supplemental Products

Human LRRC4 Antibody Summary

Species Reactivity
Detects human LRRC4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human LRRC3 is observed.
Polyclonal Sheep IgG
Antigen Affinity-purified
Chinese hamster ovary cell line CHO-derived recombinant human LRRC4
Accession # Q9HBW1
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human LRRC4
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry LRRC4 antibody in Human Brain by Immunohistochemistry (IHC-P). View Larger

LRRC4 in Human Brain. LRRC4 was detected in immersion fixed paraffin-embedded sections of human brain (cerebellum) using 15 µg/mL Sheep Anti-Human LRRC4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4995) overnight at 4 °C. Tissue was stained with the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: LRRC4

LRRC4 (Leu-rich repeat/LRR-containing protein 4; also brain tumor-associated protein) is a 55 kDa (predicted) member of the Leu-rich protein family. It is expressed on neurons and astrocytes, and antagonizes the signaling pathways for cytokines and growth factors. It is reduced in expression in tumors. Human LRRC4 is a type I transmembrane protein that is 653 amino acids (aa) in length. It contains a 489 aa extracellular region (aa 39-527), and a 105 aa cytoplasmic domain. The extracellular region shows nine LRRs (aa 74-288), a C2 type Ig-like domain (aa 354-440), and a Thr rich segment (aa 455-526). Over aa 39-527, human LRRC4 is 98% aa identical to both mouse and canine LRRC4, respectively.

Long Name
Leucine-rich Repeat Containing 4
Entrez Gene IDs
64101 (Human); 192198 (Mouse); 641521 (Rat)
Alternate Names
BAG; Brain Tumor Associated Protein LRRC4; Brain Tumor-Associated Protein BAG; Leucine Rich Repeat Containing 4; Leucine-Rich Repeat-Containing 4; Leucine-Rich Repeat-Containing Protein 4; LRRC4; NAG14; Nasopharyngeal Carcinoma-Associated Gene 14 Protein; Netrin-G2 Ligand; NGL-2

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