NKG2A, also known as CD159a, is a type II transmembrane receptor having a single extracellular lectin-like domain and a cytoplasmic ITIM motif. It associates with CD94 and is expressed on NK cells and some activated T cell populations. The NKG2A/CD94 complex delivers an inhibitory signal upon recognition of its ligand, HLA-E.
Human NKG2A/CD159a Biotinylated Antibody
R&D Systems | Catalog # FAB1059B
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Biotin
Antibody Source
Monoclonal Mouse IgG2A Clone # 131411
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Product Specifications
Immunogen
BaF3 mouse pro-B cell line transfected with human NKG2A and CD94
Specificity
Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human NKG2A/CD159a Biotinylated Antibody
Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKG2A/CD159a Biotinylated Monoclonal Antibody (Catalog # FAB1059B) or (B) Mouse IgG2ABiotinylated Isotype Control (Catalog # IC003B) followed by Streptavidin-Phycoerythrin (Catalog # F0040).Applications for Human NKG2A/CD159a Biotinylated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
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Advanced Features
- Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
- Spillover Popups - Visualize the spectra of individual fluorochromes
- Antigen Density Selector - Match fluorochrome brightness with antigen density
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: NKG2A/CD159a
Long Name
Natural Killer G2A
Alternate Names
CD159a, Klrc1, NKG2
Gene Symbol
KLRC1
Additional NKG2A/CD159a Products
Product Documents for Human NKG2A/CD159a Biotinylated Antibody
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human NKG2A/CD159a Biotinylated Antibody
For research use only
Related Research Areas
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