Human PI 3-Kinase p110 beta Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB2686S Datasheet / COA / SDS

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FAB2686S-100UG

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Human PI 3-Kinase p110 beta Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects endogenous human PI 3-kinase p110 beta in Western blots.

Source

Monoclonal Mouse IgG2b Clone # 269020

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PI 3-Kinase p110Î²
Met152-Val349
Accession # P42338

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PI 3-Kinase p110 beta

Class IA phosphoinositide 3-kinases (PI 3-kinases) are a family of p85/p110 heterodimeric lipid kinases that function as signal transducers downstream of growth factor receptors, mainly receptor tyrosine kinases. Mammals express three class IA catalytic subunits: p110 alpha, p110 beta, and p110δ. Reports suggest that the p110 beta subunit may have special importance in promoting cell proliferation.

Long Name

Protein Tyrosine Phosphatase 1B

Entrez Gene IDs

5291 (Human)

Alternate Names

P110BETA; PI 3Kinase p110 beta; PI 3-Kinase p110 beta; PI3K; PI3KBETA; PIK3C1; PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; PIK3CB