Human PI 3-Kinase p110 beta Antibody Summary
Accession # P42338
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Human PI 3-Kinase p110 beta by Western Blot. Western blot shows lysates of A431 human epithelial carcinoma cell line and Jurkat human acute T cell leukemia cell line. PVDF membrane was probed with 1 µg/mL of Human PI 3-Kinase p110 beta Monoclonal Antibody (Catalog # MAB2686) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PI 3-Kinase p110 beta at approximately 110 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PI 3-Kinase p110 beta
Class IA phosphoinositide 3-kinases (PI 3-kinases) are a family of p85/p110 heterodimeric lipid kinases that function as signal transducers downstream of growth factor receptors, mainly receptor tyrosine kinases. Mammals express three class IA catalytic subunits: p110 alpha, p110 beta, and p110δ. Reports suggest that the p110 beta subunit may have special importance in promoting cell proliferation.
Citations for Human PI 3-Kinase p110 beta Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
Filter your results:
The PI3K subunits, P110&alpha and P110&beta are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer
Authors: L Zhang, Y Li, Q Wang, Z Chen, X Li, Z Wu, C Hu, D Liao, W Zhang, ZS Chen
Mol. Cancer, 2020;19(1):10.
Sample Types: Whole Cells
Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis.
Authors: Matsuda N, Yamamoto S, Yokoo H, Tobe K, Hattori Y
Crit. Care Med., 2009;37(10):2791-9.
Sample Types: Tissue Homogenates
Applications: Western Blot
No product specific FAQs exist for this product, however you mayView all Antibody FAQs
Reviews for Human PI 3-Kinase p110 beta Antibody
Average Rating: 4 (Based on 2 Reviews)
Have you used Human PI 3-Kinase p110 beta Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Antibody was printed on custom arrays and incubated with fluorescently labeled human EDTA plasma