Human PI 3-Kinase p110 gamma Alexa Fluor® 405-conjugated Antibody
Human PI 3-Kinase p110 gamma Alexa Fluor® 405-conjugated Antibody Summary
Lys298-Leu467
Accession # P48736
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: PI 3-Kinase p110 gamma
Class I phosphoinositide 3-kinases (PI 3-Kinases) are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IA PI 3‑Kinases (p110 alpha, beta and δ) are typically activated through receptor tyrosine kinase signaling, whereas p110 gamma, the single member of class IB, is activated by seven‑transmembrane G‑protein‑coupled receptors (GPCRs). While p110 alpha and beta are ubiquitiously expressed, expression of p110 gamma is mainly restricted to cells of the hematopoietic system.
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