Human Smoothened (NP_005622) VersaClone cDNA

Name: Human Smoothened (NP_005622) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2144
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC2144

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_005622

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Smoothened

Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas. Smoothened expression has been documented in bladder, blood, brain, the central nervous system, skin, and ureter. ESTs have been isolated from amnion, bone, brain, breast, embryo, eye, heart, nerve, and skin libraries.

Alternate Names

bnb, CRJS, FZD11, Gx, SMO, SMOH

Entrez Gene IDs

6608 (Human); 319757 (Mouse); 25273 (Rat)

Gene Symbol

SMO

UniProt

NP_005622

Additional Smoothened Products

Product Documents for Human Smoothened (NP_005622) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human Smoothened (NP_005622) VersaClone cDNA

For research use only

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