Human TGF-beta 1 Quantikine ELISA Kit

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Citations (217)
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  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (100 uL), Serum (40 uL), EDTA Plasma (40 uL), Urine (100 uL)
  • Sensitivity
    15.4 pg/mL
  • Assay Range
    31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Urine)
  • Specificity
    Natural and recombinant TGF-beta 1. This kit cross-reacts 15% with human Latent TGF-beta 1 complex and also recognizes human TGF-beta 1.2 and mouse, rat, porcine, and canine TGF-beta 1. 
  • Cross-reactivity
    Cross-reactivity observed with 1 or more available related molecules.Cross-species reactivity observed with 1 or more species tested.
  • Interference
    Interference observed with 1 or more available related molecules.
Ancillary Reagent Kit Available
DY010 , Sample Activation Kit 1 - Please Inquire
Control Available
QC01-1 , Quantikine Immunoassay Control Group 1 - Please Inquire
Product Summary
The Quantikine Human TGF-beta 1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TGF-beta 1 in acid activated cell culture supernates, serum, plasma, and urine. It contains recombinant human TGF-beta 1 expressed by CHO cells and has been shown to quantitate the recombinant factor accurately. Results obtained using natural TGF-beta 1 showed linear curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit will provide accurate quantitation for both recombinant and natural human TGF-beta 1.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Urine
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 22 21 22
Mean 88 198 816 97 209 826
Standard Deviation 3 4.9 19.6 8.1 17.3 47
CV% 3.4 2.5 2.4 8.4 8.3 5.7

Serum, EDTA Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 28 37 30
Mean 78 180 695 79 185 730
Standard Deviation 2.3 3.4 17.3 7.2 17.2 46.8
CV% 2.9 1.9 2.5 9.1 9.3 6.4

Recovery

The recovery of TGF-beta 1 spiked to levels throughout the range of the assay followed by activation was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=4) 99 86-115
Urine (n=3) 96 88-100
Linearity
To assess the linearity of the assay, activated samples containing and/or spiked with high concentrations of TGF-beta 1 were diluted with Calibrator Diluent and then assayed.
 TGF-beta 1 [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: TGF-beta 1

Transforming Growth Factor Beta 1, 2, and 3 (TGF-beta 1, TGF-beta 2, and TGF-beta 3) are highly pleiotropic cytokines that virtually all cell types secrete. TGF-beta molecules are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial-mesenchymal transition. Targeted deletions of these genes in mice show that each TGF-beta isoform has some non-redundant functions: TGF-beta 1 is involved in hematopoiesis and endothelial differentiation; TGF-beta 2 affects development of cardiac, lung, craniofacial, limb, eye, ear, and urogenital systems; and TGF-beta 3 influences palatogenesis and pulmonary development. The full range of in vitro biological activities of TGF-beta 5 has not yet been explored. However, TGF-beta 1, TGF-beta 2, TGF-beta 3, and TGF-beta 5 have been found to be largely interchangeable in an inhibitory bioassay, and it is anticipated that TGF-beta 5 will show a spectrum of activities similar to the other TGF-beta family members. To date, the production of TGF-beta 5 has only been demonstrated in Xenopus.

TGF-beta ligands are initially synthesized as precursor proteins that undergo proteolytic cleavage. The mature segments form active ligand dimers via a disulfide-rich core consisting of the characteristic 'cysteine knot'. TGF-beta signaling begins with binding to a complex of the accessory receptor betaglycan (also known as TGF-beta RIII) and a type II serine/threonine kinase receptor termed TGF-beta RII. This receptor then phosphorylates and activates a type I serine/threonine kinase receptor, either ALK-1 or TGF-beta RI (also called ALK-5). The activated type I receptor phosphorylates and activates Smad proteins that regulate transcription. Use of other signaling pathways that are Smad-independent allows for distinct actions observed in response to TGF-beta in different contexts.

  • Long Name:
    Transforming Growth Factor beta 1
  • Entrez Gene IDs:
    7040 (Human); 21803 (Mouse); 59086 (Rat); 397078 (Porcine); 100033900 (Equine)
  • Alternate Names:
    CEDLAP; DPD1; latency-associated peptide; TGFB; TGFB1; TGF-beta 1 protein; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1; transforming growth factor beta-1; transforming growth factor, beta 1
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

217 Citations: Showing 1 - 10
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Species
Sample Type
  1. The role of pro-fibrotic biomarkers in paroxysmal and persistent atrial fibrillation
    Authors: AE Stanciu, RG Vatasescu, MM Stanciu, N Serdarevic, M Dorobantu
    Cytokine, 2018;103(0):63-68.
    Species: Human
    Sample Type: Serum
  2. Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells
    Authors: B Chen, Y Liang, L Chen, Y Wei, Y Li, W Zhao, J Wu
    J Cancer, 2018;9(7):1248-1258.
    Species: Human
    Sample Type: Cell Culture Supernates
  3. Suppressive regulatory T cells and latent transforming growth factor-?-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis
    Authors: T Hanada, S Tsuji, M Nakayama, S Wakinoue, K Kasahara, F Kimura, T Mori, K Ogasawara, T Murakami
    Reprod. Biol. Endocrinol., 2018;16(1):9.
    Species: Human
    Sample Type: Plasma
  4. MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression
    Authors: Q Cao, F Liu, K Ji, N Liu, Y He, W Zhang, L Wang
    J. Exp. Clin. Cancer Res, 2017;36(1):29.
    Species: Human
    Sample Type: Cell Culture Supernates
  5. Comparison of fibrin glue and Vicryl sutures in conjunctival autografting for pterygium surgery
    Authors: X Wang, Y Zhang, L Zhou, R Wei, L Dong
    Mol. Vis., 2017;23(0):275-285.
    Species: Human
    Sample Type: Tears
  6. Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine
    Authors: D Capper, A von Deimli, AA Brandes, AF Carpentier, S Kesari, JM Sepulveda-, HR Wheeler, O Chinot, L Cher, JP Steinbach, P Specenier, J Rodon, A Cleverly, C Smith, I Gueorguiev, C Miles, SC Guba, D Desaiah, ST Estrem, MM Lahn, W Wick
    Int J Mol Sci, 2017;18(5):.
    Species: Human
    Sample Type: Plasma
  7. HTRA1 and TGF-?1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration
    Authors: GM Tosi, E Caldi, G Neri, E Nuti, D Marigliani, S Baiocchi, C Traversi, G Cevenini, A Tarantello, F Fusco, F Nardi, M Orlandini, F Galvagni
    Invest. Ophthalmol. Vis. Sci, 2017;58(1):162-167.
    Species: Human
    Sample Type: Aqueous humor
  8. Vitamin D supplementation improves serum markers associated with hepatic fibrogenesis in chronic hepatitis C patients: A randomized, double-blind, placebo-controlled study
    Authors: P Komolmit, S Kimtrakool, S Suksawatam, K Thanapirom, K Chattrasop, P Thaimai, C Chirathawo, Y Poovorawan
    Sci Rep, 2017;7(1):8905.
    Species: Human
    Sample Type: Serum
  9. Differential effects of amnion and chorion membrane extracts on osteoblast-like cells due to the different growth factor composition of the extracts
    Authors: YY Go, SE Kim, GJ Cho, SW Chae, JJ Song
    PLoS ONE, 2017;12(8):e0182716.
    Species: Human
    Sample Type: Tissue Homogenates
  10. Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma
    Authors: H Kusumoto, Y Shintani, R Kanzaki, T Kawamura, S Funaki, M Minami, I Nagatomo, E Morii, M Okumura
    Cancer Sci., 2017;108(3):528-535.
    Species: Human
    Sample Type: Cell Culture Supernates
  11. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome
    Authors: KC Clark, FA Fierro, EM Ko, NJ Walker, B Arzi, CG Tepper, H Dahlenburg, A Cicchetto, A Kol, L Marsh, WJ Murphy, N Fazel, DL Borjesson
    Stem Cell Res Ther, 2017;8(1):69.
    Species: Human
    Sample Type: Cell Culture Supernates
  12. Platelet-rich plasma induces post-natal maturation of immature articular cartilage and correlates with LOXL1 activation
    Authors: Y Zhang, BJ Morgan, R Smith, CR Fellows, C Thornton, M Snow, LW Francis, IM Khan
    Sci Rep, 2017;7(1):3699.
    Species: Human
    Sample Type: Serum
  13. Higher plasma transforming growth factor (TGF)-? is associated with kidney disease in older community dwelling adults
    Authors: T Mehta, P Buzkova, JR Kizer, L Djousse, M Chonchol, KJ Mukamal, M Shlipak, JH Ix, D Jalal
    BMC Nephrol, 2017;18(1):98.
    Species: Human
    Sample Type: Plasma
  14. Multiplex serum protein analysis reveals potential mechanisms and markers of response to hyperimmune caprine serum in systemic sclerosis
    Authors: N Quillinan, KE Clark, B Youl, J Vernes, D McIntosh, S Haq, CP Denton
    Arthritis Res. Ther, 2017;19(1):45.
    Species: Human
    Sample Type: Serum
  15. Estradiol promotes breast cancer cell migration via recruitment and activation of neutrophils
    Authors: G Vazquez Ro, A Abrahamsso, LD Jensen, C Dabrosin
    Cancer Immunol Res, 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  16. Inflammatory Mediators in Tracheal Aspirates of Preterm Infants Participating in a Randomized Trial of Inhaled Nitric Oxide
    Authors: M Laube, E Amann, U Uhlig, Y Yang, HW Fuchs, M Zemlin, JC Mercier, RF Maier, HD Hummler, S Uhlig, UH Thome
    PLoS ONE, 2017;12(1):e0169352.
    Species: Human
    Sample Type: Tissue Secretion
  17. Fibronectin-guided migration of carcinoma collectives
    Authors: S Gopal, L Veracini, D Grall, C Butori, S Schaub, S Audebert, L Camoin, E Baudelet, A Radwanska, S Beghelli-d, SM Violette, PH Weinreb, S Rekima, M Ilie, A Sudaka, P Hofman, E Van Obberg
    Nat Commun, 2017;8(0):14105.
    Species: Human
    Sample Type: Cell Culture Supernates
  18. Short term storage stability at room temperature of two different platelet-rich plasma preparations from equine donors and potential impact on growth factor concentrations
    Authors: G Hauschild, F Geburek, G Gosheger, M Eveslage, D Serrano, A Streitbrg, S Johannlke, D Menzel, R Mischke
    BMC Vet. Res, 2017;13(1):7.
    Species: Equine
    Sample Type: Plasma
  19. High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection
    Authors: Z Meng, Y Zhang, Z Wei, P Liu, J Kang, Y Zhang, D Ma, C Ke, Y Chen, J Luo, Z Gong
    BMC Gastroenterol, 2017;17(1):6.
    Species: Human
    Sample Type: Serum
  20. The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro
    Authors: M Bernardi, F Agostini, K Chieregato, E Amati, C Durante, M Rassu, M Ruggeri, S Sella, E Lombardi, M Mazzucato, G Astori
    J Transl Med, 2017;15(1):90.
    Species: Human
    Sample Type: Cell Lysates
  21. Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis
    Authors: L Dou, Y Wu, Q Yan, J Wang, Y Zhang, P Ji
    Sci Rep, 2017;7(1):7300.
    Species: Human
    Sample Type: Cell Culture Supernates
  22. A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes
    Authors: Q Li, AP Hutchins, Y Chen, S Li, Y Shan, B Liao, D Zheng, X Shi, Y Li, WY Chan, G Pan, S Wei, X Shu, D Pei
    Nat Commun, 2017;8(0):15166.
    Species: Human
    Sample Type: Cell Culture Supernates
  23. Effects of combined rAAV-mediated TGF-? and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates
    Authors: K Tao, A Rey-Rico, J Frisch, JK Venkatesan, G Schmitt, H Madry, J Lin, M Cucchiarin
    J Exp Orthop, 2017;4(1):4.
    Species: Human
    Sample Type: Bone Marrow Aspirates
  24. Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study
    Authors: E Peyster, J Chen, HI Feldman, AS Go, J Gupta, N Mitra, Q Pan, A Porter, M Rahman, D Raj, M Reilly, MR Wing, W Yang, RR Townsend,
    Am. J. Hypertens., 2017;30(4):400-408.
    Species: Human
    Sample Type: Plasma
  25. Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells
    Authors: J Liu, G Song, X Lin, X Pang, T Meng
    Exp Ther Med, 2017;13(4):1447-1455.
    Species: Human
    Sample Type: Cell Culture Supernates
  26. Effects of Acute Confinement Stress-induced Hypothalamic-Pituitary Adrenal Axis Activation and Concomitant Peripheral and Central Transforming Growth Factor-?1 Measures in Nonhuman Primates
    Authors: JD Coplan, S Gopinath, CG Abdallah, J Margolis, W Chen, BA Scharf, LA Rosenblum, OA Batuman, EL Smith
    Chronic Stress (Thousand Oaks), 2017;1(0):.
    Species: Primate
    Sample Type: Serum
  27. Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells
    Authors: W Katagiri, T Kawai, M Osugi, Y Sugimura-W, K Sakaguchi, T Kojima, T Kobayashi
    Maxillofac Plast Reconstr Surg, 2017;39(1):8.
    Species: Human
    Sample Type: Cell Culture Supernates
  28. Preparing Platelet-Rich Plasma with Whole Blood Harvested Intraoperatively During Spinal Fusion
    Authors: B Shen, Z Zhang, NF Zhou, YF Huang, YJ Bao, DS Wu, YD Zhang
    Med. Sci. Monit., 2017;23(0):3578-3584.
    Species: Human
    Sample Type: Plasma
  29. Increased expression of latent TGF-?-binding protein 4 affects the fibrotic process in scleroderma by TGF-?/SMAD signaling
    Authors: J Lu, Q Liu, L Wang, W Tu, H Chu, W Ding, S Jiang, Y Ma, X Shi, W Pu, X Zhou, L Jin, J Wang, W Wu
    Lab. Invest, 2017;0(0):.
    Species: Human
    Sample Type: Plasma
  30. TGF-?1 serum concentrations and receptor expressions in the lens capsular of dogs with diabetes mellitus
    Authors: S Neumann, J Linek, G Loesenbeck, J Schüttler, S Gaedke
    Open Vet J, 2017;7(1):12-15.
    Species: Canine
    Sample Type: Serum
  31. MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2
    Authors: GA Howe, K Kazda, CL Addison
    PLoS ONE, 2017;12(10):e0185619.
    Species: Human
    Sample Type: Cell Culture Supernates
  32. Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps
    Authors: NA Johdi, L Mazlan, I Sagap, R Jamal
    Cytokine, 2017;99(0):35-42.
    Species: Human
    Sample Type: Serum
  33. MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study
    Authors: G Schmalz, I Davarpanah, J Jäger, RF Mausberg, B Krohn-Grim, J Schmidt, R Haak, U Sack, D Ziebolz
    J Microbiol Immunol Infect, 2017;0(0):.
    Species: Human
    Sample Type: Serum
  34. rAAV-mediated overexpression of TGF-? via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model
    Authors: A Rey-Rico, JK Venkatesan, G Schmitt, A Concheiro, H Madry, C Alvarez-Lo, M Cucchiarin
    Int J Nanomedicine, 2017;12(0):6985-6996.
    Species: Human
    Sample Type: Cell Culture Supernates
  35. Predictive Value of Serum IFN-? inducible Protein-10 and IFN-?/IL-4 Ratio for Liver Fibrosis Progression in CHB Patients
    Authors: Y Wang, W Yu, C Shen, W Wang, L Zhang, F Liu, H Sun, Y Zhao, H Che, C Zhao
    Sci Rep, 2017;7(0):40404.
    Species: Human
    Sample Type: Serum
  36. Tacrolimus Modulates TGF-? Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells
    Authors: J Bennett, H Cassidy, C Slattery, MP Ryan, T McMorrow
    J Clin Med, 2016;5(5):.
    Species: Human
    Sample Type: Cell Culture Supernates
  37. Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
    Sci Rep, 2016;6(0):29029.
    Species: Human
    Sample Type: Cell Culture Supernates
  38. Transforming Growth Factor-?1 as a Predictor for the Development of Hepatocellular Carcinoma: A Nested Case-Controlled Study
    EBioMedicine, 2016;0(0):.
    Species: Human
    Sample Type: Serum
  39. Alterations in the Fecal Microbiota of Patients with HIV-1 Infection: An Observational Study in A Chinese Population
    Sci Rep, 2016;6(0):30673.
    Species: Human
    Sample Type: Serum
  40. Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke
    Stem Cells Int, 2016;2016(0):6104780.
    Species: Human
    Sample Type: Cell Culture Supernates
  41. Circulating Fibrocytes Are Increased in Neonates with Bronchopulmonary Dysplasia
    Authors: Chun Li
    PLoS ONE, 2016;11(6):e0157181.
    Species: Human
    Sample Type: Plasma
  42. The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-? signaling
    Cell Death Dis, 2016;7(11):e2443.
    Species: Human
    Sample Type: Cell Culture Supernates
  43. Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells
    J Exp Clin Cancer Res, 2016;35(1):147.
    Species: Human
    Sample Type: Plasma
  44. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
    EBioMedicine, 2016;10(0):282-90.
    Species: Human
    Sample Type: Cell Culture Supernates
  45. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis
    JCI Insight, 2016;1(20):e90954.
    Species: Human
    Sample Type: Cell Culture Supernates
  46. Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
    Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
    Respir Res, 2016;17(1):36.
    Species: Human
    Sample Type: Cell Culture Supernates
  47. Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
    Authors: Ingrid C Weel
    PLoS ONE, 2016;11(6):e0157584.
    Species: Human
    Sample Type: Tissue Homogenates
  48. Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis
    Authors: Warren C Plaisted
    PLoS ONE, 2016;11(6):e0157620.
    Species: Human
    Sample Type: Whole Cells
  49. Exosomes in Human Breast Milk Promote EMT
    Authors: W Qin, Y Tsukasaki, S Dasgupta, N Mukhopadhy, M Ikebe, ER Sauter
    Clin Cancer Res, 2016;0(0):.
    Species: Human
    Sample Type: Cell Lysates
  50. Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells, GLP-1 secretion and inflammatory markers in patients with type 2 diabetes: randomized crossover clinical study.
    Authors: Tostes G, Cunha M, Fukui R, Correia M, Rocha D, Dos Santos R, da Silva M
    Diabetol Metab Syndr, 2016;8(0):1.
    Species: Human
    Sample Type: Serum
  51. Biological effects of plasma rich in growth factors (PRGF) on human endometrial fibroblasts
    Authors: Gorka Orive
    Eur. J. Obstet. Gynecol. Reprod. Biol., 2016;206(0):125-130.
    Species: Human
    Sample Type: Plasma
  52. Urine interleukin-6, interleukin-8 and transforming growth factor ?1 in infants with urinary tract infection and asymptomatic bacteriuria
    Authors: Ma?gorzata Pa?czyk-To
    Cent Eur J Immunol, 2016;41(3):260-267.
    Species: Human
    Sample Type: Urine
  53. Macrophage TGF-?1 and the Proapoptotic Extracellular Matrix Protein BIGH3 Induce Renal Cell Apoptosis in Prediabetic and Diabetic Conditions
    Authors: RJ Moritz, RG LeBaron, CF Phelix, R Rupaimoole, HS Kim, A Tsin, R Asmis
    Int J Clin Med, 2016;7(7):496-510.
    Species: Human
    Sample Type: Cell Culture Supernates
  54. Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia
    Authors: El?bieta Radzikowsk
    Adv Clin Exp Med, 2016;25(5):871-878.
    Species: Human
    Sample Type: Serum
  55. Growth factor and pro-inflammatory cytokine contents in platelet-rich plasma (PRP), plasma rich in growth factors (PRGF), advanced platelet-rich fibrin (A-PRF), and concentrated growth factors (CGF)
    Authors: Hideo Masuki
    Int J Implant Dent, 2016;2(1):19.
    Species: Human
    Sample Type: Platelet Rich Plasma
  56. Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study.
    Authors: Gupta J, Dominic E, Fink J, Ojo A, Barrows I, Reilly M, Townsend R, Joffe M, Rosas S, Wolman M, Patel S, Keane M, Feldman H, Kusek J, Raj D
    PLoS ONE, 2015;10(4):e0124772.
    Species: Human
    Sample Type: Plasma
  57. Alcohol inhibits osteopontin-dependent transforming growth factor-beta1 expression in human mesenchymal stem cells.
    Authors: Driver J, Weber C, Callaci J, Kothari A, Zapf M, Roper P, Borys D, Franzen C, Gupta G, Wai P, Zhang J, Denning M, Kuo P, Mi Z
    J Biol Chem, 2015;290(16):9959-73.
    Species: Human
    Sample Type: Cell Culture Supernates
  58. Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.
    Authors: Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, Miyazaki T, Mizumoto K, Tanaka M, Oda Y
    Lab Invest, 2015;95(2):193-206.
    Species: Human
    Sample Type: Cell Culture Supernates
  59. Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells.
    Authors: Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K
    PLoS ONE, 2015;10(3):e0120192.
    Species: Human
    Sample Type: Cell Culture Supernates
  60. Transforming Growth Factor Beta (TGF-beta) Is a Muscle Biomarker of Disease Progression in ALS and Correlates with Smad Expression.
    Authors: Si Y, Kim S, Cui X, Zheng L, Oh S, Anderson T, AlSharabati M, Kazamel M, Volpicelli-Daley L, Bamman M, Yu S, King P
    PLoS ONE, 2015;10(9):e0138425.
    Species: Human
    Sample Type: Tissue Homogenates
  61. Asporin Is a Fibroblast-Derived TGF-beta1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.
    Authors: Maris P, Blomme A, Palacios A, Costanza B, Bellahcene A, Bianchi E, Gofflot S, Drion P, Trombino G, Di Valentin E, Cusumano P, Maweja S, Jerusalem G, Delvenne P, Lifrange E, Castronovo V, Turtoi A
    PLoS Med, 2015;12(9):e1001871.
    Species: Human
    Sample Type: Cell Culture Supernates
  62. Immune Parameters That Distinguish Multiple Sclerosis Patients from Patients with Other Neurological Disorders at Presentation.
    Authors: Mouzaki A, Rodi M, Dimisianos N, Emmanuil A, Kalavrizioti D, Lagoudaki R, Grigoriadis N, Papathanasopoulos P
    PLoS ONE, 2015;10(8):e0135434.
    Species: Human
    Sample Type: Serum
  63. WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
    Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
    BMC Gastroenterol, 2015;15(0):173.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  64. Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-beta signaling.
    Authors: Tulley S, Chen W
    J Biol Chem, 2014;289(22):15280-96.
    Species: Human
    Sample Type: Cell Culture Supernates
  65. Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
    Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
    Br J Cancer, 2014;110(1):26-33.
    Species: Human
    Sample Type: Plasma
  66. Different subsets of macrophages in patients with new onset tuberculous pleural effusion.
    Authors: Tang Y, Hua S, Qin G, Xu L, Jiang Y
    PLoS ONE, 2014;9(2):e88343.
    Species: Human
    Sample Type: Serum
  67. Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study.
    Authors: Apinjoh T, Anchang-Kimbi J, Njua-Yafi C, Ngwai A, Mugri R, Clark T, Rockett K, Kwiatkowski D, Achidi E
    Malar J, 2014;13(0):236.
    Species: Human
    Sample Type: Plasma
  68. Expansion of activated regulatory T cells by myeloid-specific chemokines via an alternative pathway in CSF of bacterial meningitis patients.
    Authors: Shi G, Han J, Liu G, Hao Y, Ma Y, Li T, Wu X, Zhang H, Liu Y, Wang B, Kong Y, Zhou J, Zeng H
    Eur J Immunol, 2014;44(2):420-30.
    Species: Human
    Sample Type: Cell Culture Supernates
  69. Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity.
    Authors: Krishnan G, Chatterjee N
    Mol Cell Neurosci, 2014;59(0):10-23.
    Species: Human
    Sample Type: Cell Culture Supernates
  70. Angiopoietin-like protein 2 induced by mechanical stress accelerates degeneration and hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis.
    Authors: Nakamura T, Okada T, Endo M, Kadomatsu T, Taniwaki T, Sei A, Odagiri H, Masuda T, Fujimoto T, Nakamura T, Oike Y, Mizuta H
    PLoS ONE, 2014;9(1):e85542.
    Species: Human
    Sample Type: Cell Culture Supernates
  71. The clinical correlation of regulatory T cells and cyclic adenosine monophosphate in enterovirus 71 infection.
    Authors: Wang, Shih-Min, Chen, I-Chun, Liao, Yu-Ting, Liu, Ching-Ch
    PLoS ONE, 2014;9(7):e102025.
    Species: Human
    Sample Type: Plasma
  72. Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells.
    Authors: Iudicone, Paola, Fioravanti, Daniela, Bonanno, Giuseppi, Miceli, Michelin, Lavorino, Claudio, Totta, Pierange, Frati, Luigi, Nuti, Marianna, Pierelli, Luca
    J Transl Med, 2014;12(0):28.
    Species: Human
    Sample Type: Cell Culture Supernates
  73. Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells.
    Authors: Berardis S, Lombard C, Evraerts J, El Taghdouini A, Rosseels V, Sancho-Bru P, Lozano J, van Grunsven L, Sokal E, Najimi M
    PLoS ONE, 2014;9(1):e86137.
    Species: Human
    Sample Type: Cell Culture Supernates
  74. Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice.
    Authors: Fujimura K, Wakino S, Minakuchi H, Hasegawa K, Hosoya K, Komatsu M, Kaneko Y, Shinozuka K, Washida N, Kanda T, Tokuyama H, Hayashi K, Itoh H
    PLoS ONE, 2014;9(4):e94373.
    Species: Human
    Sample Type: Cell Culture Supernates
  75. The role of TGF-beta1-miR-21-ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells.
    Authors: Jiang Y, Chen X, Tian W, Yin X, Wang J, Yang H
    Br J Cancer, 2014;111(4):772-80.
    Species: Human
    Sample Type: Cell Culture Supernates
  76. Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-beta.
    Authors: Alcaraz L, Exposito J, Chuvin N, Pommier R, Cluzel C, Martel S, Sentis S, Bartholin L, Lethias C, Valcourt U
    J Cell Biol, 2014;205(3):409-28.
  77. Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate.
    Authors: Chou M, Burnouf T, Wang T
    PLoS ONE, 2014;9(6):e99145.
    Species: Human
    Sample Type: Cell Culture Supernates
  78. The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21.
    Authors: Soria-Valles C, Gutierrez-Fernandez A, Guiu M, Mari B, Fueyo A, Gomis R, Lopez-Otin C
    Oncogene, 2014;33(23):3054-63.
    Species: Human
    Sample Type: Cell Culture Supernates
  79. Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin.
    Authors: Karagiannis G, Schaeffer D, Cho C, Musrap N, Saraon P, Batruch I, Grin A, Mitrovic B, Kirsch R, Riddell R, Diamandis E
    Mol Oncol, 2014;8(2):178-95.
    Species: Human
    Sample Type: Cell Culture Supernates
  80. The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia.
    Authors: Chou C, Lin F, Tsai H, Chang S
    BMC Pulm Med, 2014;14(0):182.
    Species: Human
    Sample Type: BALF
  81. The peritoneum is both a source and target of TGF-beta in women with endometriosis.
    Authors: Young V, Brown J, Saunders P, Duncan W, Horne A
    PLoS ONE, 2014;9(9):e106773.
  82. Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling.
    Authors: Santhekadur P, Akiel M, Emdad L, Gredler R, Srivastava J, Rajasekaran D, Robertson C, Mukhopadhyay N, Fisher P, Sarkar D
    FEBS Open Bio, 2014;4(0):353-61.
    Species: Human
    Sample Type: Cell Culture Supernates
  83. Anti-inflammatory and anti-fibrotic profile of fish oil emulsions used in parenteral nutrition-associated liver disease.
    Authors: Pastor-Clerigues A, Marti-Bonmati E, Milara J, Almudever P, Cortijo J
    PLoS ONE, 2014;9(12):e115404.
    Species: Human
    Sample Type: Serum
  84. Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-beta/Smad2/3 pathway.
    Authors: Tu B, Peng Z, Fan Q, DU L, Yan W, Tang T
    Exp Cell Res, 2014;320(1):164-73.
    Species: Human
    Sample Type: Cell Culture Supernates
  85. Differential knockdown of TGF-beta ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.
    Authors: Horie M, Saito A, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, Suzuki H, Kohyama T, Nagase T
    BMC Cancer, 2014;14(0):580.
    Species: Human
    Sample Type: Cell Culture Supernates
  86. TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement.
    Authors: Bialas A, Stevens B
    Nat Neurosci, 2013;16(12):1773-82.
    Species: Rat
    Sample Type: Cell Culture Supernates
  87. Tranilast enhances the anti-tumor effects of tamoxifen on human breast cancer cells in vitro.
    Authors: Darakhshan S, Ghanbari A
    J Biomed Sci, 2013;20(0):76.
    Species: Human
    Sample Type: Cell Culture Supernates
  88. Platelet rich plasma clot releasate preconditioning induced PI3K/AKT/NFkappaB signaling enhances survival and regenerative function of rat bone marrow mesenchymal stem cells in hostile microenvironments.
    Authors: Peng Y, Huang S, Wu Y, Cheng B, Nie X, Liu H, Ma K, Zhou J, Gao D, Feng C, Yang S, Fu X
    Stem Cells Dev, 2013;22(24):3236-51.
    Species: Human
    Sample Type: Platelet-Rich Plasma
  89. Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
    Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
    PLoS ONE, 2013;8(12):e83042.
    Species: Human
    Sample Type: Plasma
  90. Neutrophil microparticles modulate cytokine production by natural killer cells.
    Authors: Pliyev B, Kalintseva M, Abdulaeva S, Yarygin K, Savchenko V
    Cytokine, 2013;65(2):126-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  91. Effect of platelet lysate on human cells involved in different phases of wound healing.
    Authors: Barsotti M, Losi P, Briganti E, Sanguinetti E, Magera A, Al Kayal T, Feriani R, Di Stefano R, Soldani G
    PLoS ONE, 2013;8(12):e84753.
    Species: Human
    Sample Type: Cell Lysates
  92. Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature.
    Authors: Loubaki L, Hadj-Salem I, Fakhfakh R, Jacques E, Plante S, Boisvert M, Aoudjit F, Chakir J
    PLoS ONE, 2013;8(12):e81983.
    Species: Human
    Sample Type: Cell Culture Supernates
  93. Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer.
    Authors: Armstrong A, Haggman M, Stadler W, Gingrich J, Assikis V, Polikoff J, Damber J, Belkoff L, Nordle O, Forsberg G, Carducci M, Pili R
    Clin Cancer Res, 2013;19(24):6891-901.
    Species: Human
    Sample Type: Plasma
  94. Circulating levels of transforming growth factor-betaeta (TGF-beta) and chemokine (C-X-C motif) ligand-1 (CXCL1) as predictors of distant seeding of circulating tumor cells in patients with metastatic breast cancer.
    Authors: Divella R, Daniele A, Savino E, Palma F, Bellizzi A, Giotta F, Simone G, Lioce M, Quaranta M, Paradiso A, Mazzocca A
    Anticancer Res, 2013;33(4):1491-7.
    Species: Human
    Sample Type: Plasma
  95. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells.
    Authors: Andre T, Meuleman N, Stamatopoulos B, De Bruyn C, Pieters K, Bron D, Lagneaux L
    PLoS ONE, 2013;8(3):e59756.
    Species: Human
    Sample Type: Cell Culture Supernates
  96. TGF-beta mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.
    Authors: Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, Nwajei F, Marini F, Andreeff M, Kuratsu J, Lang F
    Cancer Res, 2013;73(7):2333-44.
    Species: Human
    Sample Type: Cell Culture Supernates
  97. Vitamin D favorably alters the cancer promoting prostaglandin cascade.
    Authors: Qin W, Smith C, Jensen M, Holick M, Sauter E
    Anticancer Res, 2013;33(9):3861-6.
    Species: Human
    Sample Type: Serum
  98. Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia.
    Authors: Pontikoglou C, Kastrinaki M, Klaus M, Kalpadakis C, Katonis P, Alpantaki K, Pangalis G, Papadaki H
    Stem Cells Dev, 2013;22(9):1329-41.
    Species: Human
    Sample Type: Cell Culture Supernates
  99. Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.
    Authors: Lauzier A, Charbonneau M, Paquette M, Harper K, Dubois CM
    Arthritis Res. Ther., 2012;14(4):R159.
    Species: Human
    Sample Type: Cell Culture Supernates
  100. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
    Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
    PLoS Pathog., 2012;8(1):e1002486.
    Species: Human
    Sample Type: Cell Culture Supernates
  101. Urinary neutrophil gelatinase-associated lipocalin is a potential biomarker for renal damage in patients with systemic lupus erythematosus.
    Authors: Yang CC, Hsieh SC, Li KJ, Wu CH, Lu MC, Tsai CY, Yu CL
    J. Biomed. Biotechnol., 2012;2012(0):759313.
    Species: Human
    Sample Type: Urine
  102. Central role of SREBP-2 in the pathogenesis of osteoarthritis.
    Authors: Kostopoulou F, Gkretsi V, Malizos KN, Iliopoulos D, Oikonomou P, Poultsides L, Tsezou A
    PLoS ONE, 2012;7(5):e35753.
    Species: Human
    Sample Type: Cell Culture Supernates
  103. Hypoxia potentiates glioma-mediated immunosuppression.
    Authors: Wei J, Wu A, Kong LY, Wang Y, Fuller G, Fokt I, Melillo G, Priebe W, Heimberger AB
    PLoS ONE, 2012;6(1):e16195.
    Species: Human
    Sample Type: Cell Culture Supernates
  104. IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma.
    Authors: Bianchetti L, Marini M, Isgro M, Bellini A, Schmidt M, Mattoli S
    Biochem Biophys Res Commun, 2012;426(1):116-21.
    Species: Human
    Sample Type: Cell Culture Supernates
  105. Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy.
    Authors: Qin W, Zhang K, Kliethermes B, Ruhlen RL, Browne EP, Arcaro KF, Sauter ER
    BMC Cancer, 2012;12(0):100.
    Species: Human
    Sample Type: Milk
  106. Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor.
    Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F
    Clin. Exp. Rheumatol., 2012;30(4):534-42.
    Species: Human
    Sample Type: Serum
  107. Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury.
    Authors: Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M
    Crit. Care Med., 2012;40(1):21-8.
    Species: Human
    Sample Type: BALF
  108. Altered circulating levels of matrix metalloproteinases and inhibitors associated with elevated type 2 cytokines in lymphatic filarial disease.
    Authors: Anuradha R, George JP, Pavankumar N, Kumaraswami V, Nutman TB, Babu S
    PLoS Negl Trop Dis, 2012;6(6):e1681.
    Species: Human
    Sample Type: Platelet-Poor Plasma
  109. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.
    Authors: Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ
    Mol. Biol. Cell, 2011;22(10):1686-98.
    Species: Canine
    Sample Type: Cell Culture Supernates
  110. The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans.
    Authors: Di Meglio P, Di Cesare A, Laggner U
    PLoS ONE, 2011;6(2):e17160.
    Species: Human
    Sample Type: Serum
  111. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
    Authors: Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y
    J. Clin. Invest., 2011;121(11):4548-66.
    Species: Human
    Sample Type: Recombinant Protein
  112. Oral cholecalciferol decreases albuminuria and urinary TGF-beta1 in patients with type 2 diabetic nephropathy on established renin-angiotensin-aldosterone system inhibition.
    Authors: Kim MJ, Frankel AH, Donaldson M, Darch SJ, Pusey CD, Hill PD, Mayr M, Tam FW
    Kidney Int., 2011;80(8):851-60.
    Species: Human
    Sample Type: Urine
  113. Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.
    Authors: Rauch C, Feifel E, Amann EM, Spotl HP, Schennach H, Pfaller W, Gstraunthaler G
    ALTEX, 2011;28(4):305-16.
    Species: Human
    Sample Type: Cell Lysates
  114. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.
    Authors: Scheel C, Eaton E, Li S, Chaffer C, Reinhardt F, Kah K, Bell G, Guo W, Rubin J, Richardson A, Weinberg R
    Cell, 2011;145(6):926-40.
    Species: Human
    Sample Type: Cell Culture Supernates
  115. Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion.
    Authors: Henriksson ML, Edin S, Dahlin AM, Oldenborg PA, Oberg Ã…, Van Guelpen B, Rutegard J, Stenling R, Palmqvist R
    Am. J. Pathol., 2011;178(3):1387-94.
    Species: Human
    Sample Type: Cell Culture Supernates
  116. Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor beta and Notch signaling.
    Authors: Robinson AP, Foraker JE, Ylostalo J, Prockop DJ
    Stem Cells Dev., 2011;20(2):289-300.
    Species: Human
    Sample Type: Cell Culture Supernates
  117. Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring.
    Authors: Holmlund U, Amoudruz P, Johansson MA, Haileselassie Y, Ongoiba A, Kayentao K, Traore B, Doumbo S, Schollin J, Doumbo O, Montgomery SM, Sverremark-Ekstrom E
    Clin. Exp. Immunol., 2010;162(3):500-9.
    Species: Human
    Sample Type: Milk
  118. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
    Authors: Tso GH, Law HK, Tu W
    Stem Cells, 2010;28(5):939-54.
    Species: Human
    Sample Type: Cell Culture Supernates
  119. Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells.
    Authors: Ramirez JM, Brembilla NC, Sorg O, Chicheportiche R, Matthes T, Dayer JM, Saurat JH, Roosnek E, Chizzolini C
    Eur. J. Immunol., 2010;40(9):2450-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  120. Involvement of regulatory T cells in the immunosuppression characteristic of patients with paracoccidioidomycosis.
    Authors: Ferreira MC, de Oliveira RT, da Silva RM, Blotta MH, Mamoni RL
    Infect. Immun., 2010;78(10):4392-401.
    Species: Human
    Sample Type: Cell Culture Supernates
  121. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma.
    Authors: Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, Lin P, Bousquet J, Van Steen K
    J. Allergy Clin. Immunol., 2010;126(5):962.
    Species: Human
    Sample Type: Tissue Homogenates
  122. Hydrochloride pioglitazone decreases urinary TGF-beta1 excretion in type 2 diabetics.
    Authors: Hu YY, Ye SD, Zhao LL, Zheng M, Chen Y
    Eur. J. Clin. Invest., 2010;40(7):571-4.
    Species: Human
    Sample Type: Urine
  123. Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis.
    Authors: Ha CT, Wu JA, Irmak S, Lisboa FA, Dizon AM, Warren JW, Ergun S, Dveksler GS
    Biol. Reprod., 2010;83(1):27-35.
    Species: Human
    Sample Type: Cell Culture Supernates
  124. Regulation of transforming growth factor-beta1 by insulin in prediabetic African Americans.
    Authors: Huan Y, DeLoach S, Daskalakis C
    Kidney Int., 2010;78(3):318-24.
    Species: Human
    Sample Type: Urine
  125. Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells.
    Authors: Liang X, Moseman EA, Farrar MA
    Blood, 2010;115(24):5041-52.
    Species: Human
    Sample Type: Cell Culture Supernates
  126. Increased cytokine production in IL-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling (SOCS).
    Authors: Nold-Petry CA, Nold MF, Nielsen JW, Bustamante A, Zepp JA, Storm KA, Hong JW, Kim SH, Dinarello CA
    J. Biol. Chem., 2009;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  127. Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells.
    Authors: Oh JY, Kim MK, Shin MS, Wee WR, Lee JH
    Cytokine, 2009;46(1):100-3.
    Species: Human
    Sample Type: Cell Culture Supernates
  128. MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice.
    Authors: Margulis A, Nocka KH, Wood NL, Wolf SF, Goldman SJ, Kasaian MT
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(2):L236-47.
    Species: Human
    Sample Type: Cell Culture Supernates
  129. Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans.
    Authors: Schirmer SH, van Royen N, Moerland PD, Fledderus JO, Henriques JP, van der Schaaf RJ, Vis MM, Baan J, Koch KT, Horrevoets AJ, Hoefer IE, Piek JJ
    J. Am. Coll. Cardiol., 2009;53(23):2141-7.
  130. Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model.
    Authors: Gogly B, Fournier B, Couty L, Naveau A, Brasselet C, Durand E, Coulomb B, Lafont A
    J. Mol. Cell. Cardiol., 2009;47(2):296-303.
    Species: Rabbit
    Sample Type: Cell Culture Supernates
  131. Tumor-derived pancreatic stellate cells promote pancreatic cancer cell invasion through release of thrombospondin-2.
    Authors: Farrow B, Berger DH, Rowley D
    J. Surg. Res., 2009;156(1):155-60.
    Species: Human
    Sample Type: Cell Culture Supernates
  132. Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis.
    Authors: Quintas-Cardama A, Kantarjian HM, Manshouri T, Thomas D, Cortes J, Ravandi F, Garcia-Manero G, Ferrajoli A, Bueso-Ramos C, Verstovsek S
    J. Clin. Oncol., 2009;27(28):4760-6.
    Species: Human
    Sample Type: Plasma
  133. Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis.
    Authors: Lee HS, Myers A, Kim J
    Am. J. Respir. Crit. Care Med., 2009;180(11):1056-67.
    Species: Human
    Sample Type: Nasal Lavage
  134. Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.
    Authors: Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM
    PLoS ONE, 2009;4(11):e7916.
    Species: Human
    Sample Type: Plasma
  135. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
    Authors: Chase JC, Celli J, Bosio CM
    Infect. Immun., 2009;77(1):180-95.
    Species: Human
    Sample Type: Cell Culture Supernates
  136. Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway.
    Authors: Gomez D, Al Haj Zen A, Borges LF, Philippe M, Gutierrez PS, Jondeau G, Michel JB, Vranckx R
    J. Pathol., 2009;218(1):131-42.
    Species: Human
    Sample Type: Cell Culture Supernates
  137. Isoflavones regulate secretion of leukemia inhibitory factor and transforming growth factor {beta} and expression of glycodelin in human endometrial epithelial cells.
    Authors: Xu JW, Yasui N, Ikeda K, Pan WJ, Watanabe J, Shiotani M, Yanaihara A, Miki T, Yamori Y
    J. Endocrinol., 2008;196(2):425-33.
    Species: Human
    Sample Type: Cell Culture Supernates
  138. The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.
    Authors: Rojas A, Meherem S, Kim YH, Washington MK, Willis JE, Markowitz SD, Grady WM
    Int. J. Cancer, 2008;123(1):14-21.
    Species: Human
    Sample Type: Cell Culture Supernates
  139. Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers.
    Authors: Shariat SF, Karam JA, Walz J, Roehrborn CG, Montorsi F, Margulis V, Saad F, Slawin KM, Karakiewicz PI
    Clin. Cancer Res., 2008;14(12):3785-91.
    Species: Human
    Sample Type: Plasma
  140. Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.
    Authors: Tabata T, Kawakatsu H, Maidji E, Sakai T, Sakai K, Fang-Hoover J, Aiba M, Sheppard D, Pereira L
    Am. J. Pathol., 2008;172(4):1127-40.
    Species: Human
    Sample Type: Cell Culture Supernates
  141. Oncogenic and angiogenic growth factors accumulate during routine storage of apheresis platelet concentrates.
    Authors: Kanter J, Khan SY, Kelher M, Gore L, Silliman CC
    Clin. Cancer Res., 2008;14(12):3942-7.
    Species: Human
    Sample Type: Platelet-Poor Plasma
  142. ADAMTS-1 metalloproteinase promotes tumor development through the induction of a stromal reaction in vivo.
    Authors: Rocks N, Paulissen G, Quesada-Calvo F, Munaut C, Gonzalez ML, Gueders M, Hacha J, Gilles C, Foidart JM, Noel A, Cataldo DD
    Cancer Res., 2008;68(22):9541-50.
    Species: Human
    Sample Type: Cell Culture Supernates
  143. Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
    Authors: Van Aarsen LA, Leone DR, Ho S, Dolinski BM, McCoon PE, LePage DJ, Kelly R, Heaney G, Rayhorn P, Reid C, Simon KJ, Horan GS, Tao N, Gardner HA, Skelly MM, Gown AM, Thomas GJ, Weinreb PH, Fawell SE, Violette SM
    Cancer Res., 2008;68(2):561-70.
    Species: Human
    Sample Type: Cell Culture Supernates
  144. Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis.
    Authors: Pulichino AM, Wang IM, Caron A, Mortimer J, Auger A, Boie Y, Elias JA, Kartono A, Xu L, Menetski J, Sayegh CE
    Am. J. Respir. Cell Mol. Biol., 2008;39(3):324-36.
    Species: Human
    Sample Type: BALF
  145. Up-regulated macrophage migration inhibitory factor protects apoptosis of dermal fibroblasts in patients with systemic sclerosis.
    Authors: Kim JY, Kwok SK, Hur KH, Kim HJ, Kim NS, Yoo SA, Kim WU, Cho CS
    Clin. Exp. Immunol., 2008;152(2):328-35.
    Species: Human
    Sample Type: Serum
  146. Pharmacodynamics and Pharmacokinetics of the Novel Thrombopoietin Mimetic Peptide RWJ-800088 in Humans.
    Authors: Liem-Moolenaar M, Cerneus D, Molloy C, End D, Brown K, de Kam M, Cohen A, van Hensbergen Y, Burggraaf J
    2008;84(0):481.
    Species: Human
    Sample Type: Plasma
  147. Optimizing tacrolimus therapy in the maintenance of renal allografts: 12-month results.
    Authors: Bolin P, Shihab FS, Mulloy L, Henning AK, Gao J, Bartucci M, Holman J, First MR
    Transplantation, 2008;86(1):88-95.
    Species: Human
    Sample Type: Serum
  148. Amidic alginate hydrogel for nucleus pulposus replacement.
    Authors: Leone G, Torricelli P, Chiumiento A, Facchini A, Barbucci R
    J Biomed Mater Res A, 2008;84(2):391-401.
    Species: Human
    Sample Type: Cell Culture Supernates
  149. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
    Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2007;210(1):192-200.
    Species: Human
    Sample Type: Cell Culture Supernates
  150. Functional diversity of T-cell subpopulations in subacute and chronic hypersensitivity pneumonitis.
    Authors: Barrera L, Mendoza F, Zuniga J, Estrada A, Zamora AC, Melendro EI, Ramirez R, Pardo A, Selman M
    Am. J. Respir. Crit. Care Med., 2007;177(1):44-55.
    Species: Human
    Sample Type: BALF
  151. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.
    Authors: Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW
    Cancer Res., 2007;67(9):4244-53.
    Species: Human
    Sample Type: Cell Culture Supernates
  152. Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling.
    Authors: Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F
    Stem Cells, 2007;26(1):279-89.
    Species: Human
    Sample Type: Cell Culture Supernates
  153. PRO 2000 elicits a decline in genital tract immune mediators without compromising intrinsic antimicrobial activity.
    Authors: Keller MJ, Guzman E, Hazrati E, Kasowitz A, Cheshenko N, Wallenstein S, Cole AL, Cole AM, Profy AT, Wira CR, Hogarty K, Herold BC
    AIDS, 2007;21(4):467-76.
    Species: Human
    Sample Type: Vaginal Lavage
  154. Calcineurin modulates the catabolic and anabolic activity of chondrocytes and participates in the progression of experimental osteoarthritis.
    Authors: Yoo SA, Park BH, Yoon HJ, Lee JY, Song JH, Kim HA, Cho CS, Kim WU
    Arthritis Rheum., 2007;56(7):2299-311.
    Species: Human
    Sample Type: Cell Culture Supernates
  155. 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis.
    Authors: Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR
    Cytokine, 2007;40(2):128-34.
    Species: Human
    Sample Type: Cell Culture Supernates
  156. Serum biobank certification and the establishment of quality controls for biological fluids: examples of serum biomarker stability after temperature variation.
    Authors: Chaigneau C, Cabioch T, Beaumont K, Betsou F
    Clin. Chem. Lab. Med., 2007;45(10):1390-5.
    Species: Human
    Sample Type: Serum
  157. Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells.
    Authors: Nazareth MR, Broderick L, Simpson-Abelson MR, Kelleher RJ, Yokota SJ, Bankert RB
    J. Immunol., 2007;178(9):5552-62.
    Species: Human
    Sample Type: Cell Culture Supernates
  158. Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis.
    Authors: Koivisto H, Hietala J, Anttila P, Niemela O
    Dig. Dis. Sci., 2007;53(2):500-5.
    Species: Human
    Sample Type: Serum
  159. Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C.
    Authors: Manigold T, Shin EC, Mizukoshi E, Mihalik K, Murthy KK, Rice CM, Piccirillo CA, Rehermann B
    Blood, 2006;107(11):4424-32.
    Species: Primate - Pan troglodytes (Chimpanzee)
    Sample Type: Cell Culture Supernates
  160. Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
    Authors: Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ
    J. Immunol., 2006;176(6):3788-95.
    Species: Human
    Sample Type: Cell Culture Supernates
  161. Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation.
    Authors: Herrmann S, Green J, Weber T, Scharfenberger A
    Bone, 2006;39(5):1156-63.
    Species: Human
    Sample Type: Tissue Homogenates
  162. ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells.
    Authors: Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, Yagi J, Dianzani U
    Eur. J. Immunol., 2006;36(10):2601-12.
    Species: Human
    Sample Type: Cell Culture Supernates
  163. The potential of adiponectin in driving arthritis.
    Authors: Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U
    J. Immunol., 2006;176(7):4468-78.
    Species: Human
    Sample Type: Cell Culture Supernates
  164. Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node.
    Authors: Ito M, Minamiya Y, Kawai H, Saito S, Saito H, Nakagawa T, Imai K, Hirokawa M, Ogawa J
    J. Immunol., 2006;176(9):5637-43.
    Species: Human
    Sample Type: Tissue Homogenates
  165. Albumin induces cellular fibrosis by upregulating transforming growth factor-beta ligand and its receptors in renal distal tubule cells.
    Authors: Liu HC, Liao TN, Lee TC, Chuang LY, Guh JY, Liu SF, Hu MS, Yang YL, Lin SH, Hung MY, Huang JS, Hung TJ, Chen CD, Chiang TA, Chan JY, Chen SY
    J. Cell. Biochem., 2006;97(5):956-68.
    Species: Canine
    Sample Type: Cell Culture Supernates
  166. The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
    Authors: Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
    Blood, 2006;108(3):947-55.
    Species: Human
    Sample Type: Cell Culture Supernates
  167. Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions.
    Authors: Borrelli V, di Marzo L, Sapienza P, Colasanti M, Moroni E, Cavallaro A
    Surgery, 2006;140(3):454-63.
    Species: Human
    Sample Type: Plasma
  168. Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
    Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
    Gut, 2006;56(2):243-52.
    Species: Human
    Sample Type: Cell Culture Supernates
  169. In vivo IL-10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF-beta in the lung.
    Authors: Nakagome K, Dohi M, Okunishi K, Tanaka R, Miyazaki J, Yamamoto K
    Thorax, 2006;61(10):886-94.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  170. Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kappaB pathway.
    Authors: Lee KY, Ho SC, Lin HC, Lin SM, Liu CY, Huang CD, Wang CH, Chung KF, Kuo HP
    Am. J. Respir. Cell Mol. Biol., 2006;35(4):407-14.
    Species: Human
    Sample Type: Cell Culture Supernates
  171. Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men.
    Authors: Pagura SM, Thomas SG, Woodhouse LJ, Ezzat S, Marks P
    J. Orthop. Res., 2005;23(2):397-405.
    Species: Human
    Sample Type: Synovial Fluid
  172. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.
    Authors: Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N
    J. Allergy Clin. Immunol., 2005;117(1):103-10.
    Species: Human
    Sample Type: Cell Culture Supernates
  173. Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses.
    Authors: O'Bryan MK
    Am. J. Physiol. Regul. Integr. Comp. Physiol., 2005;288(6):R1744-55.
    Species: Rat
    Sample Type: Tissue Homogenates
  174. Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation.
    Authors: Voo KS, Peng G, Guo Z, Fu T, Li Y, Frappier L, Wang RF
    Cancer Res., 2005;65(4):1577-86.
    Species: Human
    Sample Type: Cell Culture Supernates
  175. Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
    Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
    Microbes Infect., 2005;7(3):427-36.
    Species: Human
    Sample Type: Serum
  176. Messenger RNA expression of target genes in the urinary sediment of patients with chronic kidney diseases.
    Authors: Szeto CC, Chan RW, Lai KB, Szeto CY, Chow KM, Li PK, Lai FM
    Nephrol. Dial. Transplant., 2005;20(1):105-13.
    Species: Human
    Sample Type: Urine
  177. Role of transforming growth factor-beta in breast milk for initiation of IgA production in newborn infants.
    Authors: Ogawa J, Sasahara A, Yoshida T, Sira MM, Futatani T, Kanegane H, Miyawaki T
    Early Hum. Dev., 2004;77(1):67-75.
    Species: Human
    Sample Type: Colostrum
  178. Dose response of bone mass to dietary arachidonic acid in piglets fed cow milk-based formula.
    Authors: Blanaru JL, Kohut JR, Fitzpatrick-Wong SC, Weiler HA
    Am. J. Clin. Nutr., 2004;79(1):139-47.
    Species: Porcine
    Sample Type: Plasma
  179. Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice.
    Authors: Saika S, Kono-Saika S, Tanaka T, Yamanaka O, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Yoo J, Flanders KC, Roberts AB
    Lab. Invest., 2004;84(10):1245-58.
    Species: Human
    Sample Type: Cell Culture Supernates
  180. Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria.
    Authors: Chaiyaroj SC, Rutta AS, Muenthaisong K, Watkins P, Na Ubol M, Looareesuwan S
    Acta Trop., 2004;89(3):319-27.
    Species: Human
    Sample Type: Plasma
  181. Transforming growth factor beta at clinical onset of Type 1 diabetes mellitus. A pilot study.
    Authors: Flores L, Näf S, Hernaez R, Conget I, Gomis R, Esmatjes E
    Diabet. Med., 2004;21(8):818-22.
    Species: Human
    Sample Type: Plasma
  182. Markers of wound healing in vocal fold secretions from patients with laryngeal pathology.
    Authors: Branski RC, Rosen CA, Verdolini K, Hebda PA
    Ann. Otol. Rhinol. Laryngol., 2004;113(1):23-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  183. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
    Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W
    J. Immunol., 2004;173(7):4433-42.
    Species: Human
    Sample Type: Cell Culture Supernates
  184. Fractalkine reduces N-methyl-d-aspartate-induced calcium flux and apoptosis in human neurons through extracellular signal-regulated kinase activation.
    Authors: Deiva K, Geeraerts T, Salim H, Leclerc P, Hery C, Hugel B, Freyssinet JM, Tardieu M
    Eur. J. Neurosci., 2004;20(12):3222-32.
    Species: Human
    Sample Type: Cell Culture Supernates
  185. The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation.
    Authors: Kyriakides TR, Foster MJ, Keeney GE, Tsai A, Giachelli CM, Clark-Lewis I, Rollins BJ, Bornstein P
    Am. J. Pathol., 2004;165(6):2157-66.
    Species: Human
    Sample Type: Sponge Fluid
  186. Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries.
    Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL
    J. Androl., 2004;25(2):250-4.
    Species: Human
    Sample Type: Seminal Plasma
  187. Experimental study of the effect of platelet-rich plasma on osteogenesis in rabbit.
    Authors: Zhang CQ, Yuan T, Zeng BF
    Chin. Med. J., 2004;117(12):1853-5.
    Species: Rabbit
    Sample Type: Plasma
  188. Attenuation of reperfusion-induced systemic inflammation by preconditioning with nitric oxide in an in situ porcine model of normothermic lung ischemia.
    Authors: Waldow T, Alexiou K, Witt W, Wagner FM, Gulielmos V, Matschke K, Knaut M
    Chest, 2004;125(6):2253-9.
    Species: Porcine
    Sample Type: Plasma
  189. Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects.
    Authors: Chen LL, Tager IB, Peden DB, Christian DL, Ferrando RE, Welch BS, Balmes JR
    Chest, 2004;125(6):2328-35.
    Species: Human
    Sample Type: BALF
  190. Attenuation of adhesion formation after cardiac surgery with a chymase inhibitor in a hamster model.
    Authors: Soga Y, Takai S, Koyama T, Okamoto Y, Ikeda T, Nishimura K, Miyazaki M, Komeda M
    J. Thorac. Cardiovasc. Surg., 2004;127(1):72-8.
    Species: Hamster
    Sample Type: Intrapleural Fluid
  191. Shifts in biochemical markers associated with wound healing in laryngeal secretions following phonotrauma: a preliminary study.
    Authors: Verdolini K, Rosen CA, Branski RC, Hebda PA
    Ann. Otol. Rhinol. Laryngol., 2003;112(12):1021-5.
    Species: Human
    Sample Type: Tissue Secretion
  192. Dual roles of IL-4 in lung injury and fibrosis.
    Authors: Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH
    J. Immunol., 2003;170(4):2083-92.
    Species: Mouse
    Sample Type: Serum
  193. Shock wave application enhances pertussis toxin protein-sensitive bone formation of segmental femoral defect in rats.
    Authors: Chen YJ, Kuo YR, Yang KD, Wang CJ, Huang HC, Wang FS
    J. Bone Miner. Res., 2003;18(12):2169-79.
    Species: Rat
    Sample Type: Serum
  194. A double-blind, placebo-controlled immunotherapy dose-response study with standardized cat extract.
    Authors: Ewbank PA, Murray J, Sanders K, Curran-Everett D, Dreskin S, Nelson HS
    J. Allergy Clin. Immunol., 2003;111(1):155-61.
    Species: Human
    Sample Type: Nasal Fluid
  195. TGF-beta in human milk is associated with wheeze in infancy.
    Authors: Oddy WH, Halonen M, Martinez FD, Lohman IC, Stern DA, Kurzius-Spencer M, Guerra S, Wright AL
    J. Allergy Clin. Immunol., 2003;112(4):723-8.
    Species: Human
    Sample Type: Milk
  196. Ovariectomy increases mitogens and platelet-induced proliferation of arterial smooth muscle.
    Authors: Bracamonte MP, Rud KS, Owen WG, Miller VM
    Am. J. Physiol. Heart Circ. Physiol., 2002;283(3):H853-60.
    Species: Porcine
    Sample Type: Cell Lysates
  197. Gene transfer of soluble TGF-beta type II receptor inhibits experimental proliferative vitreoretinopathy.
    Authors: Oshima Y, Sakamoto T, Hisatomi T, Tsutsumi C, Ueno H, Ishibashi T
    Gene Ther., 2002;9(18):1214-20.
    Species: Rabbit
    Sample Type: Vitreous Humor
  198. Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta.
    Authors: Schmidt A, Gopfert C, Vlodavsky I, Volker W, Buddecke E
    Eur. J. Cell Biol., 2002;81(3):138-44.
    Species: Bovine
    Sample Type: Cell Lysates
  199. AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression.
    Authors: Truckenmiller ME, Vawter MP, Zhang P, Conejero-Goldberg C, Dillon-Carter O, Morales N, Cheadle C, Becker KG, Freed WJ
    Exp. Neurol., 2002;175(0):318.
    Species: Rat
    Sample Type: Cell Culture Supernates
  200. Comparison of TGF-beta1 in tears following laser subepithelial keratomileusis and photorefractive keratectomy.
    Authors: Lee JB, Choe CM, Kim HS, Seo KY, Seong GJ, Kim EK
    J Refract Surg, 2002;18(2):130-4.
    Species: Human
    Sample Type: Tears
  201. Progesterone upregulates TGF-b isoforms (b1, b2, and b3) expression in normal human osteoblast-like cells.
    Authors: Luo XH, Liao EY, Su X
    Calcif. Tissue Int., 2002;71(4):329-34.
    Species: Human
    Sample Type: Cell Culture Supernates
  202. Recipient intramuscular cotransfection of naked plasmid transforming growth factor beta1 and interleukin 10 ameliorates lung graft ischemia-reperfusion injury.
    Authors: D'Ovidio F
    J. Thorac. Cardiovasc. Surg., 2002;124(2):259-69.
    Species: Rat
    Sample Type: N/A
  203. DNA microarray analysis of transforming growth factor-beta and related transcripts in nasal biopsies from patients with allergic rhinitis.
    Authors: Benson M, Carlsson B, Carlsson LM, Mostad P, Svensson PA, Cardell LO
    Cytokine, 2002;18(1):20-5.
    Species: Human
    Sample Type: Nasal Fluid
  204. Stability and activity of specific antibodies against Streptococcus mutans and Streptococcus sobrinus in bovine milk fermented with Lactobacillus rhamnosus strain GG or treated at ultra-high temperature.
    Authors: Wei H, Loimaranta V, Tenovuo J, Rokka S, Syvaoja EL, Korhonen H, Joutsjoki V, Marnila P
    Oral Microbiol. Immunol., 2002;17(1):9-15.
    Species: Bovine
    Sample Type: Colostrum
  205. Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-beta levels.
    Authors: Agarwal R, Siva S, Dunn SR, Sharma K
    Am. J. Kidney Dis., 2002;39(3):486-92.
    Species: Human
    Sample Type: Urine
  206. Impact of different modalities of continuous venovenous hemofiltration on sepsis-induced alterations in experimental pancreatitis.
    Authors: Yekebas EF, Strate T, Zolmajd S, Eisenberger CF, Erbersdobler A, Saalmuller A, Steffani K, Busch C, Elsner HA, Engelhardt M, Gillesen A, Meins J, The M, Knoefel WT, Izbicki JR
    Kidney Int., 2002;62(5):1806-18.
    Species: Porcine
    Sample Type: Hemofiltrates
  207. Estrogen inhibition of PTH-stimulated osteoclast formation and attachment in vitro: involvement of both PKA and PKC.
    Authors: Liu BY, Wu PW, Bringhurst FR, Wang JT
    Endocrinology, 2002;143(2):627-35.
    Species: Mouse
    Sample Type: Whole Cells
  208. Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function.
    Authors: Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J
    J. Am. Soc. Nephrol., 2001;12(10):2029-39.
    Species: Rat
    Sample Type: Peritoneal Fluid
  209. Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts.
    Authors: Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U
    Eur. J. Appl. Physiol., 2001;86(1):48-52.
    Species: Human
    Sample Type: Cell Culture Supernates
  210. Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation.
    Authors: Landesberg R, Roy M, Glickman RS
    J. Oral Maxillofac. Surg., 2000;58(3):297.
    Species: Human
    Sample Type: Plasma
  211. An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline.
    Authors: Otterness IG, Swindell AC, Zimmerer RO, Poole AR, Ionescu M, Weiner E
    Osteoarthr. Cartil., 2000;8(3):180-5.
    Species: Human
    Sample Type: Serum
  212. Growth factors and proinflammatory cytokines in the renal involvement of POEMS syndrome.
    Authors: Soubrier M, Sauron C, Souweine B, Larroche C, Wechsler B, Guillevin L, Piette JC, Rousset H, Deteix P
    Am. J. Kidney Dis., 1999;34(4):633-8.
    Species: Human
    Sample Type: Serum
  213. Transforming growth factor-beta in breast milk: a potential regulator of atopic disease at an early age.
    Authors: Kalliomaki M, Ouwehand A, Arvilommi H, Kero P, Isolauri E
    J. Allergy Clin. Immunol., 1999;104(6):1251-7.
    Species: Human
    Sample Type: Milk
  214. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
    Authors: Fadok, V A, Bratton, D L, Konowal, A, Freed, P W, Westcott, J Y, Henson, P M
    J Clin Invest, 1998;101(4):890-8.
    Species: Human
    Sample Type: Cell Culture Supernates
  215. Hypoxia-induced expression of VEGF is reversible in myocardial vascular smooth muscle cells.
    Authors: Gu JW, Adair TH
    Am. J. Physiol., 1997;273(2):H628-33.
    Species: Canine
    Sample Type: Cell Culture Supernates
  216. Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer.
    Authors: Chopra V, Dinh TV, Hannigan EV
    J. Cancer Res. Clin. Oncol., 1997;123(3):167-72.
    Species: Human
    Sample Type: Serum
  217. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis.
    Authors: Groux, H, O'Garra, A, Bigler, M, Rouleau, M, Antonenko, S, de Vries, J E, Roncarolo, M G
    Nature, 1997;389(6652):737-42.
    Species: Human
    Sample Type: Cell Culture Supernates
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  1. Can samples be tested without activation in Human TGF-beta 1 Quantikine® ELISA Kit, Catalog # DB100B, to determine levels of endogenously mature TGF-beta 1?

    • Catalog # DB100B is designed to measure TGF-beta 1 in activated serum and plasma samples. Activation releases TGF-beta 1 from latent TGF-beta 1 complexes. Internal tests with latent TGF-beta complex have demonstrated approximately 15% reactivity in the kit; however it is unclear whether this may be partially due to activation of latent TGF-beta 1 once added to the assay plate. Since the latent form of TGF-beta 1 may be significantly more abundant in serum and plasma, this cross-reactivity may make it difficult to measure low levels of active TGF-beta 1. Therefore, we recommend only using the kit to test activated serum and plasma samples for total TGF-beta 1 levels.

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 Human TGF-beta 1 Quantikine ELISA Kit DB100B Array DB100B
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  Anonymous 11/29/2017
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 Human TGF-beta 1 Quantikine ELISA Kit DB100B
: Human TGF-beta 1 Quantikine ELISA Kit [DB100B].

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Sample Tested Mouse lung tissue,Mouse lung tissue homogenates

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Other Experimental Details This result has been published in the PLoS ONE journal: https://doi.org/10.1371/journal.pone.0063798
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  Anonymous 07/21/2017
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Sample Tested Serum
 Human TGF-beta 1 Quantikine ELISA Kit DB100B Array DB100B
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  Anonymous 08/03/2016
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 Human TGF-beta 1 Quantikine ELISA Kit DB100B
: Human TGF-beta 1 Quantikine ELISA Kit [DB100B].

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Sample Tested Cell culture supernatant
 Human TGF-beta 1 Quantikine ELISA Kit DB100B Array DB100B
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  Anonymous 06/20/2016
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 Human TGF-beta 1 Quantikine ELISA Kit DB100B
: Human TGF-beta 1 Quantikine ELISA Kit [DB100B].

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Sample Tested Muscle tissue

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 Human TGF-beta 1 Quantikine ELISA Kit DB100B Array DB100B
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  Anonymous 05/09/2016
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 Human TGF-beta 1 Quantikine ELISA Kit DB100B
: Human TGF-beta 1 Quantikine ELISA Kit [DB100B].

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Sample Tested Bone Putty

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