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Human TNF-alpha DuoSet ELISA

DY210 264 Citations 23 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY210
DY210-05
Ancillary Products Available
DY008: DuoSet ELISA Ancillary Reagent Kit 2
Human TNF-alpha ELISA Standard Curve
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Product Details
Procedure
Citations (264)
FAQs
Supplemental Products
Reviews (23)
Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Human TNF-alpha DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
15.6 - 1,000 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human TNF-alpha. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

 

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

 

  

Data Example

Human TNF-alpha ELISA Standard Curve View Larger

Human TNF-alpha ELISA Standard Curve

Product Datasheets

Product Datasheet
COA
SDS

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: TNF-alpha

Tumor Necrosis Factor alpha (TNF-alpha ), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily (1). It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (2-5). TNF-alpha is also involved in a number of pathological conditions including asthma, Crohn's disease, rheumatoid arthritis, neuropathic pain, obesity, type 2 diabetes, septic shock, autoimmunity, and cancer (5-11). 

 Human TNF-alpha is synthesized as a 26 kDa type II transmembrane protein that consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD) (12, 13). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus monkey, and 71%-92% aa identity with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha. It is produced by a wide variety of immune, epithelial, endothelial, and tumor cells. TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (14). Cell surface TNF-alpha can both induce the lysis of tumor cells and virus infected cells, and generate its own downstream cell signaling following ligation by soluble TNF RI (15, 16). Shedding of membrane bound TNF-alpha by TACE/ ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (17-19). 
 TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (20, 21) and the hematopoietic cell-restricted 78-80 kDa TNF RII (22, 23), both of which are also expressed as homotrimers (1, 24). Both type I and type II receptors bind TNF-alpha with comparable affinity and can promote NF kappa B activation (25-28). Only TNF RI, however, contains a cytoplasmic death domain which triggers the activation of apoptosis (3, 29). Soluble forms of both types of receptors are released into human serum and urine and can neutralize the biological activity of TNF-alpha (30-32).

Long Name:
Tumor Necrosis Factor alpha
Entrez Gene IDs:
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 102139631 (Cynomolgus Monkey); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names:
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

 

Citations for Human TNF-alpha DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

264 Citations: Showing 1 - 10
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  1. Downregulation of miR-126-3p expression contributes to increased inflammatory response in placental trophoblasts in preeclampsia
    Authors: X Chu, Y Gu, W Sheng, J Sun, JA Morgan, DF Lewis, DB Cooper, CE McCathran, Y Wang
    Journal of reproductive immunology, 2021;144(0):103281.
    Species: Human
    Sample Types: Cell Culture Supernates
  2. Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes
    Authors: P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai
    PLoS ONE, 2021;16(2):e0246381.
    Species: Human
    Sample Types: Cell Culture Supernates
  3. Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae
    Authors: AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth
    PLoS ONE, 2021;16(2):e0246803.
    Species: Human
    Sample Types: Cell Culture Supernates
  4. Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
    Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
    Cell Reports, 2021;34(10):108826.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Regulation of Transcription Factor E2-2 in Human Plasmacytoid Dendritic Cells by Monocyte-Derived TNF&alpha
    Authors: HK Dewald, HJ Hurley, P Fitzgerald
    Viruses, 2020;12(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1
    Authors: P Pe?an, S Hambalkó, VT Ha, CT Nagy, C Pelyhe, D Lainš?ek, B Kenyeres, GB Brenner, A Görbe, Á Kittel, M Barteková, P Ferdinandy, M Man?ek-Keb, Z Giricz
    Int J Mol Sci, 2020;21(20):.
    Species: Human
    Sample Types: Cell Culture Supernates
  7. A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia
    Authors: P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier
    Cancer Medicine, 2020;0(0):.
    Species: Human
    Sample Types: Serum
  8. HMGB1 as a potential biomarker and therapeutic target for severe COVID-19
    Authors: R Chen, Y Huang, J Quan, J Liu, H Wang, TR Billiar, MT Lotze, HJ Zeh, R Kang, D Tang
    Heliyon, 2020;6(12):e05672.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Vibration synergistically enhances IL-1&beta and TNF-&alpha in compressed human periodontal ligament cells in the frequency-dependent manner
    Authors: S Benjakul, B Unat, P Thammanich, C Leethanaku
    J Oral Biol Craniofac Res, 2020;10(4):412-416.
    Species: Human
    Sample Types: Cell Culture Supernates
  10. 1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis
    Authors: H Kim, S Baek, SM Hong, J Lee, SM Jung, J Lee, M Cho, SK Kwok, SH Park
    J. Korean Med. Sci., 2020;35(6):e40.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. Whole-cell fungal-mediated structural transformation of anabolic drug metenolone acetate into potent anti-inflammatory metabolites
    Authors: M Siddiqui, Atia-Tul-W, A Jabeen, Y Wang, W Wang, Atta-Ur-Ra, MI Choudhary
    J Adv Res, 2020;24(0):69-78.
    Species: Aspergillus alliaceus
    Sample Types: Cell Culture Supernates
  12. CD4+FOXP3+ T Cells in Rheumatoid Arthritis Bone Marrow Are Partially Impaired
    Authors: M Massalska, A Radzikowsk, E Kuca-Warna, M Plebanczyk, M Prochorec-, U Skalska, W Kurowska, P Maldyk, E Kontny, HJ Gober, W Maslinski
    Cells, 2020;9(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  13. The non-saponin fraction of Korean Red Ginseng (KGC05P0) decreases glucose uptake and transport in�vitro and modulates glucose production via down-regulation of the PI3K/AKT pathway in�vivo
    Authors: SJ Park, D Lee, D Kim, M Lee, G In, ST Han, SW Kim, MH Lee, OK Kim, J Lee
    J Ginseng Res, 2020;44(2):362-372.
    Species: Human
    Sample Types: Serum
  14. Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-1
    Authors: T Maekawa, H Tamura, H Domon, T Hiyoshi, T Isono, D Yonezawa, N Hayashi, N Takahashi, K Tabeta, T Maeda, M Oda, A Ziogas, V? Alexaki, T Chavakis, Y Terao, G Hajishenga
    JCI Insight, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  15. Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G
    Authors: W Liu, C Li, FCK Tan, HJ Neo, YH Chan, CM Low, TL Lee
    BMC Anesthesiol, 2020;20(1):69.
    Species: Human
    Sample Types: Cell Culture Supernates
  16. Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids
    Authors: MJ Pérez, D Ivanyuk, V Panagiotak, G Di Napoli, S Kalb, D Brunetti, R Al-Shaana, SA Kaeser, SA Fraschka, M Jucker, M Zeviani, C Viscomi, M Deleidi
    Mol. Psychiatry, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Lysates
  17. Targeting PD-L1 in non-small cell lung cancer using CAR T cells
    Authors: M Liu, X Wang, W Li, X Yu, P Flores-Vil, ZY Xu-Monette, L Li, M Zhang, KH Young, X Ma, Y Li
    Oncogenesis, 2020;9(8):72.
    Species: Human
    Sample Types: Cell Culture Supernates
  18. Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival
    Authors: HF Hazlett, TH Hampton, DS Aridgides, DA Armstrong, JA Dessaint, DL Mellinger, AB Nymon, A Ashare
    Sci Rep, 2020;10(1):10935.
    Species: Human
    Sample Types: Cell Culture Supernates
  19. Anti-Inflammatory Principles from Tamarix aphylla L.: A Bioassay-Guided Fractionation Study
    Authors: AS Gadallah, Mujeeb-Ur-, Atta-Ur-Ra, S Yousuf, Atia-Tul-W, A Jabeen, MM Swilam, SAM Khalifa, HR El-Seedi, MI Choudhary
    Molecules, 2020;25(13):.
    Species: Human
    Sample Types: Cell Culture Supernates
  20. The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by &beta-Glucan
    Authors: ST Keating, L Groh, CDCC van der He, H Rodriguez, JC Dos Santos, S Fanucchi, J Okabe, H Kaipananic, JH van Puffel, L Helder, MP Noz, V Matzaraki, Y Li, LCJ de Bree, VACM Koeken, SJCFM Moorlag, VP Mourits, J Domínguez-, M Oosting, EP Bulthuis, WJH Koopman, M Mhlanga, A El-Osta, LAB Joosten, MG Netea, NP Riksen
    Cell Rep, 2020;31(3):107548.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Activation of Human &gamma&delta T Cells: Modulation by Toll-Like Receptor 8 Ligands and Role of Monocytes
    Authors: R Serrano, D Wesch, D Kabelitz
    Cells, 2020;9(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  22. Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-&kappaB Signaling Pathway in Hepatic Stellate Cells
    Authors: YH Wang, FM Suk, CL Liu, TL Chen, YC Twu, MH Hsu, YJ Liao
    Front Pharmacol, 2020;11(0):388.
    Species: Human
    Sample Types: Cell Culture Supernates
  23. Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration
    Authors: RE James, R Schalks, E Browne, I Eleftheria, CP Munoz, ND Mazarakis, R Reynolds
    Acta Neuropathol Commun, 2020;8(1):66.
    Species: Human
    Sample Types: Cell Culutre Supernatant
  24. Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review
    Authors: M Herrera, C Vera, Y Keynan, ZV Rueda
    J Immunol Res, 2020;2020(0):8074183.
    Species: Human
    Sample Types: Cell Culture Supernates
  25. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
    Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
    PLoS Pathog., 2020;16(8):e1008781.
    Species: Human
    Sample Types: Cell Culture Supernates
  26. The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore
    Authors: S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski
    Front Pharmacol, 2020;11(0):983.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. Lentiviral delivery of combinatorial CAR/CRISPRi circuit into human primary T cells is enhanced by TBK1/IKK? complex inhibitor BX795
    Authors: L Li, Y Gao, R Srivastava, W Wang, Q Xiong, Z Fang, A Pelayo, C Denson, A Goswami, R Harari-Ste, Z Yang, L Weng, LS Qi, FM Marincola
    Journal of Translational Medicine, 2020;18(1):363.
    Species: Human
    Sample Types: Cell Culture Supernates
  28. Design and characterization of Squalene-Gusperimus nanoparticles for modulation of innate immunity
    Authors: CE Navarro Ch, BJ de Haan, MM Faas, AM Smink, L Sierra, P de Vos, BL López
    Int J Pharm, 2020;590(0):119893.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Lung Surfactant Accelerates Skin Wound Healing: A Translational Study with a Randomized Clinical Phase I Study
    Authors: U Mirastschi, I Schwab, V Coger, U Zier, C Rianna, W He, K Maedler, S Kelm, A Radtke, G Belge, P Lindner, F Stahl, M Scharpenbe, L Lasota, J Timm
    Sci Rep, 2020;10(1):2581.
    Species: Human
    Sample Types: Tissue Homogenates
  30. Modeling HIV-1 neuropathogenesis using three-dimensional human brain organoids (hBORGs) with HIV-1 infected microglia
    Authors: RS Dos Reis, S Sant, H Keeney, MCE Wagner, V Ayyavoo
    Scientific Reports, 2020;10(1):15209.
    Species: Human
    Sample Types: Organoid
  31. The NRF2 stimulating agent, tin protoporphyrin, activates protective cytokine pathways in healthy human subjects and in patients with chronic kidney disease
    Authors: RA Zager, ACM Johnson
    Physiol Rep, 2020;8(18):e14566.
    Species: Human
    Sample Types: Plasma
  32. Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint
    Authors: A Floudas, N Neto, V Marzaioli, K Murray, B Moran, MG Monaghan, C Low, RH Mullan, N Rao, V Krishna, S Nagpal, DJ Veale, U Fearon
    JCI Insight, 2020;5(21):.
    Species: Human
    Sample Types: Cell Culture Supernates
  33. Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities
    Authors: J Cao, J Yang, Z Wang, M Lu, K Yue
    Carbohydr Polym, 2020;247(0):116742.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist
    Authors: H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier
    Frontiers in Pharmacology, 2020;11(0):598702.
    Species: Human
    Sample Types: Cell Culture Supernates
  35. Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes
    Authors: M De, A Bhushan, S Chinnaswam
    J Leukoc Biol, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  36. The Influence of Hypertensive Therapies on Circulating Factors: Clinical Implications for SCFAs, FGF21, TNFSF14 and TNF-&alpha
    Authors: AL Magno, LY Herat, MG Kiuchi, MP Schlaich, NC Ward, VB Matthews
    Journal of Clinical Medicine, 2020;9(9):.
    Species: Human
    Sample Types: Serum
  37. New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells
    Authors: CA Ciocan-Car, A Jurj, O Zanoaga, R Cojocneanu, LA Pop, A Moldovan, C Moldovan, AA Zimta, L Raduly, C Pop-Bica, M Buse, L Budisan, P Virag, A Irimie, SMG Diaz, I Berindan-N, C Braicu
    J Exp Clin Cancer Res, 2020;39(1):241.
    Species: Human
    Sample Types: Cell Culture Supernates
  38. Interleukin-26 activates macrophages and facilitates killing of Mycobacterium tuberculosis
    Authors: HC Hawerkamp, L van Geelen, J Korte, J Di Domizio, M Swidergall, AA Momin, FJ Guzmán-Veg, ST Arold, J Ernst, M Gilliet, R Kalscheuer, B Homey, S Meller
    Sci Rep, 2020;10(1):17178.
    Species: Human
    Sample Types: Cell Culture Supernates
  39. Anti-Inflammatory Properties of Injectable Betamethasone-Loaded Tyramine-Modified Gellan Gum/Silk Fibroin Hydrogels
    Authors: IM Oliveira, C Gonçalves, ME Shin, S Lee, RL Reis, G Khang, JM Oliveira
    Biomolecules, 2020;10(10):.
    Species: Rabbit
    Sample Types: Cell Culture Supernates
  40. SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
    Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
    medRxiv : the preprint server for health sciences, 2020;0(0):.
    Species: Human
    Sample Types: Fecal Supernates
  41. Phenotypic and functional stability of leukocytes from human peripheral blood samples: considerations for the design of immunological studies
    Authors: A Navas, L Giraldo-Pa, MD Prieto, J Cabrera, MA Gómez
    BMC Immunol., 2019;20(1):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  42. Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA
    Authors: J Russick, S Delignat, P Milanov, O Christophe, G Boros, CV Denis, PJ Lenting, SV Kaveri, S Lacroix-De
    Haematologica, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  43. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase
    Authors: PG Jobin, N Solis, Y Machado, PA Bell, NH Kwon, S Kim, CM Overall, GS Butler
    J. Biol. Chem., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
    Authors: M Dall, SAJ Trammell, M Asping, AS Hassing, M Agerholm, SG Vienberg, MP Gillum, S Larsen, JT Treebak
    J. Biol. Chem., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  45. Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes
    Authors: S Martínez-H, V Sánchez-Ga, A Herrero-Ce, Á Vinué, JT Real, JF Ascaso, DJ Burks, H González-N
    J Transl Med, 2019;17(1):222.
    Species: Human
    Sample Types: Plasma
  46. D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells
    Authors: I Ugele, ZE Cárdenas-C, K Hammon, M Wehrstein, C Bruss, K Peter, K Singer, E Gottfried, J Boesch, P Oefner, K Dettmer, K Renner, M Kreutz
    Int J Mol Sci, 2019;20(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  47. Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells
    Authors: A Islam, I Urbarova, JA Bruun, I Martinez-Z
    Eur Cell Mater, 2019;37(0):153-174.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection
    Authors: S Vangeti, J Gertow, M Yu, S Liu, F Baharom, S Scholz, D Friberg, M Starkhamma, A Ahlberg, A Smed-Sören
    J. Immunol., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  49. Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
    Authors: AK Dickey, N Chantratit, S Tandhavana, D Ducken, L Lovelace-M, S Seal, J Robertson, ND Myers, S Schwarz, MM Wurfel, S Kosamo, TE West
    PLoS Negl Trop Dis, 2019;13(5):e0007354.
    Species: Human
    Sample Types: Cell Culture Supernates
  50. High expression of S100 calgranulin genes in peripheral blood mononuclear cells from patients with Takayasu arteritis
    Authors: J Kabeerdoss, M Thomas, R Goel, H Mohan, S Danda, J L, D Danda
    Cytokine, 2019;114(0):61-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  51. Historical BCG vaccination combined with drug treatment enhances inhibition of mycobacterial growth ex vivo in human peripheral blood cells
    Authors: SA Prabowo, A Zelmer, L Stockdale, U Ojha, SG Smith, K Seifert, HA Fletcher
    Sci Rep, 2019;9(1):4842.
    Species: Human
    Sample Types: Cell Culture Supernates
  52. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
    Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
    Sci Rep, 2019;9(1):4293.
    Species: Human
    Sample Types: Cell Culture Supernates
  53. The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
    Authors: A Skjesol, M Yurchenko, K Bösl, C Gravastran, KE Nilsen, LM Grøvdal, F Agliano, F Patane, G Lentini, H Kim, G Teti, A Kumar Shar, RK Kandasamy, B Sporsheim, KK Starheim, DT Golenbock, H Stenmark, M McCaffrey, T Espevik, H Husebye
    PLoS Pathog., 2019;15(3):e1007684.
    Species: Human
    Sample Types: Cell Culture Supernates
  54. β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
    Authors: JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten
    Cell Rep, 2019;28(10):2659-2672.e6.
    Species: Human
    Sample Types: Cell Culture Supernates
  55. Evolving understanding of cardiovascular, cerebrovascular and peripheral arterial disease in people living with HIV and role of novel biomarkers. A study of the Spanish CoRIS cohort, 2004-2015
    Authors: M Masiá, S Padilla, JA García, J García-Abe, M Fernández, I Bernardino, M Montero, J Peraire, B Pernas, F Gutiérrez
    PLoS ONE, 2019;14(4):e0215507.
    Species: Human
    Sample Types: Plasma
  56. Secondhand smoke exposure and sleep-related breathing problems in toddlers
    Authors: JA Groner, L Nicholson, H Huang, JA Bauer
    Acad Pediatr, 2019;0(0):.
    Species: Human
    Sample Types: Serum
  57. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
    Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
    PLoS Pathog., 2019;15(4):e1007689.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
    Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
    Stem Cells, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. 25(OH)D3 and 1.25(OH)2D3 inhibits TNF-? expression in human monocyte derived macrophages
    Authors: A Rafique, L Rejnmark, L Heickendor, HJ Møller
    PLoS ONE, 2019;14(4):e0215383.
    Species: Human
    Sample Types: Cell Culture Supernates
  60. Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes
    Authors: K Bendí?ková, F Tidu, M De Zuani, MH Kohoutková, I Andrej?ino, A Pompeiano, S B?lášková, G Forte, T Zelante, J Fri?
    J. Leukoc. Biol., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  61. Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis
    Authors: L Su, P Pan, P Yan, Y Long, X Zhou, X Wang, R Zhou, B Wen, L Xie, D Liu
    Sci Rep, 2019;9(1):5747.
    Species: Human
    Sample Types: Cell Culture Supernates
  62. Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
    Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
    MBio, 2019;10(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
    Authors: C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong
    Mol. Cancer, 2019;18(1):64.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
    Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
    BMC Sports Sci Med Rehabil, 2019;11(0):23.
    Species: Human
    Sample Types: Saliva
  65. C13 Megastigmane Derivatives From Epipremnum pinnatum: beta-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-kappaB Signaling
    Authors: SP Pan, T Pirker, O Kunert, N Kretschmer, S Hummelbrun, SL Latkolik, J Rappai, VM Dirsch, V Bochkov, R Bauer
    Front Pharmacol, 2019;10(0):1351.
    Species: Human
    Sample Types: Cell Culture Supernates
  66. Comparative Investigation of Frankincense Nutraceuticals: Correlation of Boswellic and Lupeolic Acid Contents with Cytokine Release Inhibition and Toxicity against Triple-Negative Breast Cancer Cells
    Authors: M Schmiech, SJ Lang, J Ulrich, K Werner, LJ Rashan, T Syrovets, T Simmet
    Nutrients, 2019;11(10):.
    Species: Human
    Sample Types: Plasma
  67. Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice
    Authors: RS Carpenter, RR Jiang, FH Brennan, JCE Hall, MK Gottipati, S Niewiesk, PG Popovich
    Sci Rep, 2019;9(1):19105.
    Species: Transgenic Mouse
    Sample Types: Serum
  68. Physiologic intestinal 18F-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer
    Authors: HJ Yoon, HN Kim, JI Bang, W Lim, BI Moon, NS Paik, BS Kim, HL Kim
    Sci Rep, 2019;9(1):18273.
    Species: Human
    Sample Types: Serum
  69. Echinochrome A Reduces Colitis in Mice and Induces In Vitro Generation of Regulatory Immune Cells
    Authors: SJ Oh, Y Seo, JS Ahn, YY Shin, JW Yang, HK Kim, J Han, NP Mishchenko, SA Fedoreyev, VA Stonik, HS Kim
    Mar Drugs, 2019;17(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  70. Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
    Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2019;60(14):4820-4829.
    Species: Human
    Sample Types: Cell Culture Supernates
  71. Sulphamethazine derivatives as immunomodulating agents: New therapeutic strategies for inflammatory diseases
    Authors: H Siddiqui, HM Haniffa, A Jabeen, AU -Rahman, MI Choudhary
    PLoS ONE, 2018;13(12):e0208933.
    Species: Human
    Sample Types: Cell Culture Supernates
  72. Haplosaurus computes protein haplotypes for use in precision drug design
    Authors: W Spooner, W McLaren, T Slidel, DK Finch, R Butler, J Campbell, L Eghobamien, D Rider, CM Kiefer, MJ Robinson, C Hardman, F Cunningham, T Vaughan, P Flicek, CC Huntington
    Nat Commun, 2018;9(1):4128.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Anti-CD137 monoclonal antibody enhances trastuzumab-induced, natural killer cell-mediated cytotoxicity against pancreatic cancer cell lines with low human epidermal growth factor-like receptor 2 expression
    Authors: T Masu, M Atsukawa, K Nakatsuka, M Shimizu, D Miura, T Arai, H Harimoto, C Kondo, K Kaneko, S Futagami, C Kawamoto, H Takahashi, K Iwakiri
    PLoS ONE, 2018;13(12):e0200664.
    Species: Human
    Sample Types: Cell Culture Supernates
  74. Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function
    Authors: TM Nordgren, KL Bailey, AJ Heires, D Katafiasz, DJ Romberger
    Toxicol. Sci., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  75. Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease
    Authors: S Yi, R Chang, J Hu, Y Qiu, Q Wang, Q Cao, G Yuan, G Su, C Zhou, Y Wang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2018;59(11):4662-4669.
    Species: Human
    Sample Types: Cell Culture Supernates
  76. S100B regulates inflammatory response during osteoarthritis via fibroblast growth factor receptor 1 signaling
    Authors: L Zhu, Z Weng, P Shen, J Zhou, J Zeng, F Weng, X Zhang, H Yang
    Mol Med Rep, 2018;18(6):4855-4864.
    Species: Human
    Sample Types: Cell Culture Supernates
  77. Overproduction of IL-6 and Type-I IFN in a Lethal Case of Chikungunya Virus Infection in an Elderly Man During the 2017 Italian Outbreak
    Authors: F Colavita, S Vita, E Lalle, F Carletti, L Bordi, D Vincenti, I Pozzetto, M Aiuti, F Vairo, MR Capobianch, M Lichtner, C Castillett
    Open Forum Infect Dis, 2018;5(11):ofy276.
    Species: Human
    Sample Types: Plasma
  78. Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst-Dependent Mechanism
    Authors: RS Doster, JA Sutton, LM Rogers, DM Aronoff, JA Gaddy
    MBio, 2018;9(6):.
    Species: Human
    Sample Types:
  79. The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration
    Authors: C Dollt, J Michel, L Kloss, S Melchers, K Schledzews, K Becker, A Sauer, A Krewer, F Koll, A Schmieder
    Cell Death Dis, 2018;9(10):939.
    Species: Human
    Sample Types: Cell Culture Supernates
  80. Electrophilic properties of itaconate and derivatives regulate the�I?B?-ATF3 inflammatory axis
    Authors: M Bambouskov, L Gorvel, V Lampropoul, A Sergushich, E Loginichev, K Johnson, D Korenfeld, ME Mathyer, H Kim, LH Huang, D Duncan, H Bregman, A Keskin, A Santeford, RS Apte, R Sehgal, B Johnson, GK Amarasingh, MP Soares, T Satoh, S Akira, T Hai, C de Guzman, K Auclair, TP Roddy, SA Biller, M Jovanovic, E Klechevsky, KM Stewart, GJ Randolph, MN Artyomov
    Nature, 2018;556(7702):501-504.
    Species: Human
    Sample Types: Cell Culture Supernates
  81. TET-2 up-regulation is associated with the anti-inflammatory action of Vicenin-2
    Authors: N Hassan, A Ali, C Withycombe, M Ahluwalia, RH Al-Nasseri, A Tonks, K Morris
    Cytokine, 2018;108(0):37-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  82. CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
    Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
    Oncol Lett, 2018;15(6):9075-9080.
    Species: Human
    Sample Types: Cell Culture Supernates
  83. Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis
    Authors: ND Barth, JA Marwick, MJ Heeb, AJ Gale, AG Rossi, I Dransfield
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  84. PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia
    Authors: T Lopatina, E Favaro, C Grange, M Cedrino, A Ranghino, S Occhipinti, S Fallo, F Buffolo, DA Gaykalova, MM Zanone, R Romagnoli, G Camussi
    Sci Rep, 2018;8(1):17458.
    Species: Human
    Sample Types: Cell Culture Supernates
  85. TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
    Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
    Eur Cell Mater, 2018;35(0):13-24.
  86. Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression
    Authors: CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan
    EBioMedicine, 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  87. Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
    Authors: R Narasimhan, R Coras, SB Rosenthal, SR Sweeney, A Lodi, S Tiziani, D Boyle, A Kavanaugh, M Guma
    Arthritis Res. Ther., 2018;20(1):164.
    Species: Human
    Sample Types: Serum
  88. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
    Authors: I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, D Clancy, J Brezinova, T Hu, A Bileck, C Gerner, A Bolado, A von Kriegs, SJ Martin, F Steinberg, K Strisovsky, C Adrain
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  89. Modulation of salivary cytokines in response to alcohol, tobacco and caffeine consumption: a pilot study
    Authors: CC Sheth, RM López-Pedr, MDM Jovani-San, R González-M, V Veses
    Sci Rep, 2018;8(1):16687.
    Species: Human
    Sample Types: Saliva
  90. Fecal Galectin-3: A New Promising Biomarker for Severity and Progression of Colorectal Carcinoma
    Authors: M Jovanovic, N Gajovic, N Zdravkovic, M Jovanovic, M Jurisevic, D Vojvodic, V Maric, A Arsenijevi, I Jovanovic
    Mediators Inflamm., 2018;2018(0):8031328.
    Species: Human
    Sample Types: Feces
  91. Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen
    Authors: P Revathikum, J Estelius, U Karmakar, E Le Maître, M Korotkova, PJ Jakobsson, J Lampa
    PLoS ONE, 2018;13(2):e0193210.
    Species: Human
    Sample Types: Cell Culture Supernates
  92. Plasmodium falciparum Treated with Artemisinin-based Combined Therapy Exhibits Enhanced Mutation, Heightened Cortisol and TNF-? Induction
    Authors: AO Idowu, S Bhattachar, S Gradus, W Oyibo, Z George, C Black, J Igietseme, AA Azenabor
    Int J Med Sci, 2018;15(13):1449-1457.
    Species: Human
    Sample Types: Plasma
  93. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
    Authors: LBS Hansen, HM Roager, NB Søndertoft, RJ Gøbel, M Kristensen, M Vallès-Col, S Vieira-Sil, S Ibrügger, MV Lind, RB Mærkedahl, MI Bahl, ML Madsen, J Havelund, G Falony, I Tetens, T Nielsen, KH Allin, HL Frandsen, B Hartmann, JJ Holst, MH Sparholt, J Holck, A Blennow, JM Moll, AS Meyer, C Hoppe, JH Poulsen, V Carvalho, D Sagnelli, MD Dalgaard, AF Christense, MC Lydolph, AB Ross, S Villas-Bôa, S Brix, T Sicheritz-, K Buschard, A Linneberg, JJ Rumessen, CT Ekstrøm, C Ritz, K Kristianse, HB Nielsen, H Vestergaar, NJ Færgeman, J Raes, H Frøkiær, T Hansen, L Lauritzen, R Gupta, TR Licht, O Pedersen
    Nat Commun, 2018;9(1):4630.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. Combining Calcium Phosphates with Polysaccharides: A Bone-Inspired Material Modulating Monocyte/Macrophage Early Inflammatory Response
    Authors: H Rammal, C Bour, M Dubus, L Entz, L Aubert, SC Gangloff, S Audonnet, NB Bercu, F Boulmedais, C Mauprivez, H Kerdjoudj
    Int J Mol Sci, 2018;19(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  95. p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response
    Authors: P Arcidiacon, CM Webb, MA Brooke, H Zhou, PJ Delaney, KE Ng, DC Blaydon, A Tinker, DP Kelsell, A Chikh
    Nat Commun, 2018;9(1):1021.
    Species: Human
    Sample Types: Cell Culture Supernates
  96. Epicutaneous administration of the pattern recognition receptor agonist polyinosinic-polycytidylic acid activates the MDA5/MAVS pathway in Langerhans cells
    Authors: P Tajpara, C Schuster, E Schön, P Kienzl, M Vierhapper, M Mildner, A Elbe-Bürge
    FASEB J., 2018;0(0):fj201701090R.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Authors: B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry
    Nat Commun, 2018;9(1):242.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages
    Authors: RA Mubarak, N Roberts, RJ Mason, S Alper, HW Chu
    Respir. Res., 2018;19(1):126.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb� sorbent porous polymer beads
    Authors: MC Gruda, KG Ruggeberg, P O'Sullivan, T Guliashvil, AR Scheirer, TD Golobish, VJ Capponi, PP Chan
    PLoS ONE, 2018;13(1):e0191676.
    Species: Human
    Sample Types: Complex Sample Type
  100. Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
    Authors: I Tomašek, CJ Horwell, C Bisig, DE Damby, P Comte, J Czerwinski, A Petri-Fink, MJD Clift, B Drasler, B Rothen-Rut
    Environ. Pollut., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  101. Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
    Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
    Invest. Ophthalmol. Vis. Sci., 2018;59(2):1158-1166.
    Species: Human
    Sample Types: Cell Culture Supernates
  102. Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
    Authors: D Zhang, J Qin, L Li, G Su, G Huang, Q Cao, A Kijlstra, P Yang
    Sci Rep, 2018;8(1):4850.
    Species: Human
    Sample Types: Cell Culture Supernates
  103. Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
    Authors: N Emami-Shah, J Foster, R Kashani, P Gazinska, C Cook, J Sosabowski, J Maher, S Papa
    Nat Commun, 2018;9(1):1081.
    Species: Human
    Sample Types: Cell Culture Supernates
  104. The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
    Authors: RF Hamilton, Z Wu, S Mitra, A Holian
    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  105. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages
    Authors: M Yurchenko, A Skjesol, L Ryan, GM Richard, RK Kandasamy, N Wang, C Terhorst, H Husebye, T Espevik
    J. Cell Biol., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  106. The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages
    Authors: SR Lea, SL Reynolds, M Kaur, KD Simpson, SR Hall, EM Hessel, D Singh
    Int J Chron Obstruct Pulmon Dis, 2018;13(0):771-780.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease
    Authors: Q Zhang, H Li, S Hou, H Yu, G Su, B Deng, J Qi, C Zhou, A Kijlstra, P Yang
    Br J Ophthalmol, 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  108. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection
    Authors: S Ding, J Diep, N Feng, L Ren, B Li, YS Ooi, X Wang, KF Brulois, LL Yasukawa, X Li, CJ Kuo, DA Solomon, JE Carette, HB Greenberg
    Nat Commun, 2018;9(1):1485.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. Specific Biomarkers Associated With Neurological Complications and Congenital Central Nervous System Abnormalities From Zika Virus-Infected Patients in Brazil
    Authors: YW Kam, JA Leite, FM Lum, JJL Tan, B Lee, CC Judice, DAT Teixeira, R Andreata-S, MA Vinolo, R Angerami, MR Resende, ARR Freitas, E Amaral, RP Junior, ML Costa, JP Guida, CW Arns, LCS Ferreira, L Rénia, JL Proença-Mo, LFP Ng, FTM Costa,
    J. Infect. Dis., 2017;216(2):172-181.
    Species: Human
    Sample Types: Serum
  110. Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5
    Authors: AS Gilbert, PI Seoane, P Sephton-Cl, A Bojarczuk, R Hotham, E Giurisato, AR Sarhan, A Hillen, GV Velde, NS Gray, DR Alessi, DL Cunningham, C Tournier, SA Johnston, RC May
    Sci Adv, 2017;3(8):e1700898.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis
    Authors: J Venturini, RS Cavalcante, DV Moris, M de Assis G, AD Levorato, KH Dos Reis, MSP de Arruda, RP Mendes
    Acta Trop., 2017;0(0):.
    Species: Human
    Sample Types: Serum
  112. IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-? production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation
    Authors: E Lusty, SM Poznanski, K Kwofie, TS Mandur, DA Lee, CD Richards, AA Ashkar
    Mol. Immunol., 2017;88(0):138-147.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. Dexamethasone induced inhibition of Dectin-1 activation of antigen presenting cells is mediated via STAT-3 and NF-?B signaling pathways.
    Authors: Philipp Kotthoff, Annkristin Heine, Stefanie Andrea Erika Held, Peter Brossart
    Scientific Reports, 2017;0(0):2045-2322.
    Species: Human
    Sample Types: Cell Culture Supernates
  114. Pre- and post-surgical evaluation of the inflammatory response in patients with aortic stenosis treated with different types of prosthesis
    Authors: ME Soto, JL Salas, J Vargas-Bar, R Marquez, A Rodriguez-, R Bojalil-Pa, I Pérez-Torr, V Guarner-La
    BMC Cardiovasc Disord, 2017;17(1):100.
    Species: Human
    Sample Types: Serum
  115. Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality
    Authors: V Neuhaus, D Schaudien, T Golovina, UA Temann, C Thompson, T Lippmann, C Bersch, O Pfennig, D Jonigk, P Braubach, HG Fieguth, G Warnecke, V Yusibov, K Sewald, A Braun
    J Occup Med Toxicol, 2017;12(0):13.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells
    Authors: L Kui, GC Chan, PP Lee
    Mediators Inflamm., 2017;2017(0):7462945.
    Species: Human
    Sample Types: Cell Culture Supernates
  117. Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages
    Authors: AB Guimarães-, NC Rochael, F Oliveira, J Echevarria, EM Saraiva
    Front Immunol, 2017;8(0):523.
    Species: Human
    Sample Types: Cell Culture Supernates
  118. Increased expression of Siglec-9 in chronic obstructive pulmonary disease
    Authors: Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie
    Sci Rep, 2017;7(1):10116.
    Species: Human
    Sample Types: Cell Culture Supernates
  119. SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors
    Authors: A Taracanova, M Alevizos, A Karagkouni, Z Weng, E Norwitz, P Conti, SE Leeman, TC Theoharide
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. Minocycline modulates NF?B phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells
    Authors: AD Guerra, WE Rose, P Hematti, WJ Kao
    Stem Cell Res Ther, 2017;8(1):171.
    Species: Human
    Sample Types: Cell Culture Supernates
  121. Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
    Authors: L Chen, MS Eapen, GR Zosky
    Sci Rep, 2017;7(0):45172.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. CLEC5A is a critical receptor in innate immunity against Listeria infection
    Authors: ST Chen, FJ Li, TY Hsu, SM Liang, YC Yeh, WY Liao, TY Chou, NJ Chen, M Hsiao, WB Yang, SL Hsieh
    Nat Commun, 2017;8(1):299.
    Species: Human
    Sample Types: Cell Culture Supernates
  123. Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
    Authors: M Mihajlovic, LP van den He, JG Hoenderop, J Jansen, MJ Wilmer, AJF Westheim, WA Allebes, D Stamatiali, LB Hilbrands, R Masereeuw
    Sci Rep, 2017;7(1):7103.
    Species: Human
    Sample Types: Cell Culture Supernates
  124. On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease
    Authors: NS Hojo-Souza, DB Pereira, FS de Souza, TA de Oliveir, MS Cardoso, MS Tada, GM Zanini, DC Bartholome, RT Fujiwara, LL Bueno
    Malar. J, 2017;16(1):42.
    Species: Human
    Sample Types: Plasma
  125. Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties
    Authors: AJ Smith, B Graves, R Child, PJ Rice, Z Ma, DW Lowman, HE Ensley, KT Ryter, JT Evans, DL Williams
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  126. Associations between TNFSF4, TNFSF8 and TNFSF15 and Beh�et's disease but not VKH syndrome in Han Chinese
    Authors: Y Jiang, L Cheng, X Li, W Zhou, L Zhang
    Oncotarget, 2017;8(62):105037-105046.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions
    Authors: M Mihajlovic, M Fedecostan, MJ Oost, SKP Steenhuis, EGWM Lentjes, I Maitimu-Sm, MJ Janssen, LB Hilbrands, R Masereeuw
    Int J Mol Sci, 2017;18(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  128. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017;8(1):79.
    Species: Human
    Sample Types: Cell Culture Supernates
  129. TB lymphadenitis is associated with enhanced baseline and antigen - specific induction of Type 1 and Type 17 cytokines and reduced IL-1? and IL-18 at the site of infection
    Authors: GR Kathamuthu, K Moideen, D Baskaran, VV Banurekha, D Nair, G Sekar, R Sridhar, B Vidyajayan, G Gajendrara, DK Parandhama, A Srinivasan, S Babu
    Clin. Vaccine Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  130. Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation
    Authors: YE Bar-Ephrai, F Cornelisse, N Papazian, T Konijn, RM Hoogenboez, MA Sanders, BA Westerman, M Gönültas, J Kwekkeboom, JMM Den Haan, RM Reijmers, RE Mebius, T Cupedo
    Cell Rep, 2017;21(3):823-833.
    Species: Human
    Sample Types: Cell Culture Supernates
  131. Does Transcranial Direct Current Stimulation Combined with Peripheral Electrical Stimulation Have an Additive Effect in the Control of Hip Joint Osteonecrosis Pain Associated with Sickle Cell Disease? A Protocol for a One-Session Double Blind, Block-Randomized Clinical Trial
    Authors: TDS Lopes, WDS Silva, SB Ribeiro, CA Figueiredo, FQ Campbell, GC Daltro, A Valenzuela, P Montoya, RCS Lucena, AF Baptista
    Front Hum Neurosci, 2017;11(0):633.
    Species: Human
    Sample Types: Serum
  132. Periodontitis and type 2 diabetes among women with previous gestational diabetes: epidemiological and immunological aspects in a follow-up of three years
    Authors: RP Esteves Li, LO Cota, TA Silva, SC Cortelli, JR Cortelli, FO Costa
    J Appl Oral Sci, 2017;25(2):130-139.
    Species: Human
    Sample Types: Saliva
  133. Analgesic and anti-inflammatory properties of novel, selective, and potent EP4 receptor antagonists
    Authors: S Chandrasek, XP Yu, AK Harvey, JL Oskins, C Lin, X Wang, MJ Blanco, MJ Fisher, SL Kuklish, MA Schiffler, T Vetman, AM Warshawsky, JS York, AM Bendele, MG Chambers
    Pharmacol Res Perspect, 2017;5(3):e00316.
    Species: Human
    Sample Types: Plasma
  134. Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-? and IL-1? in third molar surgery: a triple-blind, randomized, placebo-controlled study
    Authors: AFM Albuquerqu, CSR Fonteles, DR do Val, HV Chaves, MM Bezerra, KMA Pereira, PG de Barros, BB de Lima, ECS Soares, TR Ribeiro, FWG Costa
    Int J Oral Maxillofac Surg, 2017;0(0):.
    Species: Human
    Sample Types: Tissue Homogenates
  135. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
    Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
    Immun Ageing, 2017;14(0):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  136. Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions
    Oxid Med Cell Longev, 2016;2016(0):2069290.
    Species: Human
    Sample Types: Serum
  137. Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
    Sci Rep, 2016;6(0):26662.
    Species: Human
    Sample Types: Cell Culture Supernates
  138. Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  139. Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
    Authors: Avery D Posey
    Immunity, 2016;44(6):1444-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  140. Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.
    Authors: Puig K, Manocha G, Combs C
    PLoS ONE, 2016;10(3):e0119534.
    Species: Human
    Sample Types: Cell Culture Supernates
  141. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
    Aging Cell, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  142. CD36-Mediated Uptake of Surfactant Lipids by Human Macrophages Promotes Intracellular Growth of Mycobacterium tuberculosis
    J. Immunol., 2016;197(12):4727-4735.
    Species: Human
    Sample Types: Cell Culture Supernates
  143. 17-oxo-DHA displays additive anti-inflammatory effects with fluticasone propionate and inhibits the NLRP3 inflammasome
    Sci Rep, 2016;6(0):37625.
    Species: Human
    Sample Types: Cell Culture Supernates
  144. MODELING STROMA-INDUCED DRUG RESISTANCE IN A TISSUE-ENGINEERED TUMOR MODEL OF EWING SARCOMA
    Authors: Marco Santoro
    Tissue Eng Part A, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  145. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
    Sci Rep, 2016;6(0):39035.
    Species: Human
    Sample Types: Cell Culture Supernates
  146. Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
    Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
    Sci Rep, 2016;6(0):24974.
    Species: Human
    Sample Types: Cell Culture Supernates
  147. Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
    Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
    PLoS ONE, 2016;11(4):e0153118.
    Species: Human
    Sample Types: Cell Culture Supernates
  148. Biocompatibility of primers and an adhesive used for implant-retained maxillofacial prostheses: An in�vitro analysis
    Authors: Daniela Micheline Dos Santos
    J Prosthet Dent, 2016;0(0):.
  149. DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: putative mechanisms through PPAR activation
    Authors: Rémy Bosviel
    Free Radic. Biol. Med, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  150. vIL-10-overexpressing human MSCs modulate na�ve and activated T lymphocytes following induction of collagenase-induced osteoarthritis
    Stem Cell Res Ther, 2016;7(1):74.
    Species: Human
    Sample Types: Cell Culture Supernates
  151. Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function
    Authors: C Guillou, M Fréret, E Fondard, C Derambure, G Avenel, ML Golinski, M Verdet, O Boyer, F Caillot, P Musette, T Lequerré, O Vittecoq
    Sci Rep, 2016;6(0):23796.
    Species: Human
    Sample Types: Cell Culture Supernates
  152. ?-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance
    Authors: Hendrik G Stunnenber
    Cell, 2016;167(5):1354-1368.e14.
    Species: Human
    Sample Types: Cell Culture Supernates
  153. CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes
    Sci Rep, 2016;6(0):34310.
    Species: Human
    Sample Types: Whole Cells
  154. Bortezomib treatment sensitizes oncolytic HSV-1 treated tumors to NK cell immunotherapy
    Clin Cancer Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  155. Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
    Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
    J Leukoc Biol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  156. Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1? and IL-18 in tuberculous lymphadenitis
    Cytokine, 2016;90(0):66-72.
    Species: Human
    Sample Types: Cell Culture Supernates
  157. New Anti-Inflammatory Metabolites by Microbial Transformation of Medrysone
    Authors: S Bano, AT Wahab, S Yousuf, A Jabeen, MA Mesaik, AU Rahman, MI Choudhary
    PLoS ONE, 2016;11(4):e0153951.
    Species: Human
    Sample Types: Cell Culture Supernates
  158. Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
    Authors: Ines Tomašek
    Part Fibre Toxicol, 2016;13(1):67.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating
    J Control Release, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  160. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
    Authors: Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C
    PLoS ONE, 2015;10(5):e0126159.
    Species: Human
    Sample Types: Cell Culture Supernates
  161. Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells.
    Authors: Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K
    PLoS ONE, 2015;10(9):e0138267.
    Species: Human
    Sample Types: Cell Culture Supernates
  162. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
    Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
    Reprod Biol Endocrinol, 2015;13(0):115.
    Species: Human
    Sample Types: Cell Culture Supernates
  163. Sensor Function for Butyrophilin 3A1 in Prenyl Pyrophosphate Stimulation of Human Vgamma2Vdelta2 T Cells.
    Authors: Wang H, Morita C
    J Immunol, 2015;195(10):4583-94.
    Species: Human
    Sample Types: Cell Culture Supernates
  164. Characterization of host and microbial determinants in individuals with latent tuberculosis infection using a human granuloma model.
    Authors: Guirado E, Mbawuike U, Keiser T, Arcos J, Azad A, Wang S, Schlesinger L
    MBio, 2015;6(1):e02537-14.
    Species: Human
    Sample Types: Cell Culture Supernates
  165. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
    Authors: Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D
    EMBO Mol Med, 2015;7(3):240-58.
    Species: Human
    Sample Types: Cell Culture Supernates
  166. Sourcing of an alternative pericyte-like cell type from peripheral blood in clinically relevant numbers for therapeutic angiogenic applications.
    Authors: Blocki A, Wang Y, Koch M, Goralczyk A, Beyer S, Agarwal N, Lee M, Moonshi S, Dewavrin J, Peh P, Schwarz H, Bhakoo K, Raghunath M
    Mol Ther, 2015;23(3):510-22.
    Species: Human
    Sample Types: Cell Culture Supernates
  167. Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
    Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
    PLoS ONE, 2015;10(1):e0116775.
    Species: Human
    Sample Types: BALF
  168. Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection.
    Authors: Hojo-Souza N, Pereira D, Passos L, Gazzinelli-Guimaraes P, Cardoso M, Tada M, Zanini G, Bartholomeu D, Fujiwara R, Bueno L
    BMC Infect Dis, 2015;15(0):35.
    Species: Human
    Sample Types: Plasma
  169. Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
    Authors: Jaguin M, Fardel O, Lecureur V
    PLoS ONE, 2015;10(2):e0116560.
    Species: Human
    Sample Types: Cell Culture Supernates
  170. Interleukin-23 Receptor Gene Polymorphism May Enhance Expression of the IL-23 Receptor, IL-17, TNF-alpha and IL-6 in Behcet's Disease.
    Authors: Jiang Z, Hennein L, Tao Y, Tao L
    PLoS ONE, 2015;10(7):e0134632.
    Species: Human
    Sample Types: Cell Culture Supernates
  171. Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
    Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
    PLoS ONE, 2015;10(3):e0119727.
    Species: Human
    Sample Types: Cell Culture Supernates
  172. SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.
    Authors: Xue F, Li X, Zhao X, Wang L, Liu M, Shi R, Zheng J
    PLoS ONE, 2015;10(2):e0115354.
    Species: Human
    Sample Types: Cell Culture Supernates
  173. Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells.
    Authors: Roesch F, Richard L, Rua R, Porrot F, Casartelli N, Schwartz O
    J Virol, 2015;89(23):12118-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  174. Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins.
    Authors: Yanai M, Rocha M, Matolek A, Chintalacharuvu A, Taira Y, Chintalacharuvu K, Beenhouwer D
    PLoS ONE, 2014;9(2):e89308.
    Species: Human
    Sample Types: Cell Culture Supernates
  175. Activin A as a mediator of NK-dendritic cell functional interactions.
    Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
    J Immunol, 2014;192(3):1241-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  176. The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.
    Authors: Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F
    J Biol Chem, 2014;289(3):1364-76.
  177. Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.
    Authors: Salzano S, Checconi P, Hanschmann E, Lillig C, Bowler L, Chan P, Vaudry D, Mengozzi M, Coppo L, Sacre S, Atkuri K, Sahaf B, Herzenberg L, Herzenberg L, Mullen L, Ghezzi P
    Proc Natl Acad Sci U S A, 2014;111(33):12157-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  178. Anti-inflammatory effects of green soybean extract irradiated with visible light.
    Authors: Tanaka K, Ohgo Y, Katayanagi Y, Yasui K, Hiramoto S, Ikemoto H, Nakata Y, Miyoshi N, Isemura M, Ohashi N, Imai S
    Sci Rep, 2014;4(0):4732.
    Species: Human
    Sample Types: Cell Culture Supernates
  179. TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
    Authors: Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P
    PLoS ONE, 2014;9(1):e84214.
    Species: Human
    Sample Types: Cell Culture Supernates
  180. The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation.
    Authors: Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, Fardel O, Sparfel L
    Eur J Immunol, 2014;44(5):1330-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  181. Increased prevalence of Methanosphaera stadtmanae in inflammatory bowel diseases.
    Authors: Blais Lecours P, Marsolais D, Cormier Y, Berberi M, Hache C, Bourdages R, Duchaine C
    PLoS ONE, 2014;9(2):e87734.
    Species: Human
    Sample Types: Cell Culture Supernates
  182. Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival.
    Authors: Kis-Toth K, Tsokos G
    J Immunol, 2014;192(9):4436-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  183. CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells.
    Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H
    Br J Haematol, 2014;165(1):134-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  184. Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
    Authors: Zughaier, Susu M, Kandler, Justin L, Shafer, William
    PLoS ONE, 2014;9(1):e87688.
    Species: Human
    Sample Types: Cell Culture Supernates
  185. Technical advance: live-imaging analysis of human dendritic cell migrating behavior under the influence of immune-stimulating reagents in an organotypic model of lung.
    Authors: Nguyen Hoang A, Chen P, Bjornfot S, Hogstrand K, Lock J, Grandien A, Coles M, Svensson M
    J Leukoc Biol, 2014;96(3):481-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  186. Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.
    Authors: Gleeson E, O'Donnell J, Hams E, Ni Ainle F, Kenny B, Fallon P, Preston R
    Haematologica, 2014;99(1):185-93.
    Species: Human
    Sample Types: Cell Culture Supernates
  187. Low adiposity during early infancy is associated with a low risk for developing dengue hemorrhagic fever: a preliminary model.
    Authors: Libraty D, Zhang L, Woda M, Giaya K, Kathivu C, Acosta L, Tallo V, Segubre-Mercado E, Bautista A, Obcena A, Brion J, Capeding R
    PLoS ONE, 2014;9(2):e88944.
    Species: Human
    Sample Types: Cell Culture Supernates
  188. A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
    Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
    PLoS ONE, 2014;9(5):e96943.
    Species: Human
    Sample Types: Cell Culture Supernates
  189. Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels.
    Authors: Arndts, Kathrin, Specht, Sabine, Debrah, Alexande, Tamarozzi, Francesc, Klarmann Schulz, Ute, Mand, Sabine, Batsa, Linda, Kwarteng, Alexande, Taylor, Mark, Adjei, Ohene, Martin, Coralie, Layland, Laura E, Hoerauf, Achim
    PLoS Negl Trop Dis, 2014;8(2):e2679.
    Species: Human
    Sample Types: Cell Culture Supernates
  190. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
    Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
    J Biol Chem, 2014;289(27):19231-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  191. Smac mimetics and innate immune stimuli synergize to promote tumor death.
    Authors: Beug S, Tang V, Lacasse E, Cheung H, Beauregard C, Brun J, Nuyens J, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney D, Ilkow C, Le Boeuf F, Bell J, Korneluk R
    Nat Biotechnol, 2014;32(2):182-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  192. Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population.
    Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P
    Invest Ophthalmol Vis Sci, 2013;54(13):8384-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  193. Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies.
    Authors: Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, Mo X, Cheney C, Hertlein E, Eubank T, Marsh C, Muthusamy N, Butchar J, Byrd J, Tridandapani S
    J Biol Chem, 2013;288(37):26800-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  194. Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
    Authors: Moh M, Lorenzini P, Gullo C, Schwarz H
    FASEB J, 2013;27(8):2957-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  195. Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate.
    Authors: Dabirian S, Taslimi Y, Zahedifard F, Gholami E, Doustdari F, Motamedirad M, Khatami S, Azadmanesh K, Nylen S, Rafati S
    PLoS Negl Trop Dis, 2013;7(10):e2491.
    Species: Human
    Sample Types: Cell Culture Supernates
  196. Identification of binding sites for myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 in MyD88 adapter-like (Mal).
    Authors: Bovijn C, Desmet A, Uyttendaele I, Van Acker T, Tavernier J, Peelman F
    J Biol Chem, 2013;288(17):12054-66.
    Species: Human
    Sample Types: Cell Culture Supernates
  197. Leptin up-regulates TLR2 in human monocytes.
    Authors: Jaedicke K, Roythorne A, Padget K, Todryk S, Preshaw P, Taylor J
    J Leukoc Biol, 2013;93(4):561-71.
    Species: Human
    Sample Types: Cell Culture Supernates
  198. Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein.
    Authors: Lee T, Mitchell A, Liu Lau S, An H, Rajeaskariah P, Wasinger V, Raftery M, Bryant K, Tedla N
    J Biol Chem, 2013;288(46):32873-85.
    Species: Human
    Sample Types: Cell Culture Supernates
  199. Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.
    Authors: Chantratita N, Tandhavanant S, Myers N, Seal S, Arayawichanont A, Kliangsa-Ad A, Hittle L, Ernst R, Emond M, Wurfel M, Day N, Peacock S, West T
    PLoS ONE, 2013;8(11):e81617.
    Species: Human
    Sample Types: Cell Culture Supernates
  200. Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage.
    Authors: Yamaguchi Y, Shao Z, Sharif S, Du X, Myles T, Merchant M, Harsh G, Glantz M, Recht L, Morser J, Leung L
    J Biol Chem, 2013;288(5):3097-111.
    Species: Human
    Sample Types: CSF
  201. Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease.
    Authors: Alvarez J, Zughaier S, Law J, Hao L, Wasse H, Ziegler T, Tangpricha V
    Eur J Clin Nutr, 2013;67(3):264-9.
    Species: Human
    Sample Types: Serum
  202. S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
    Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
    PLoS ONE, 2013;8(4):e62372.
  203. Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo.
    Authors: Richards FM, Tape CJ, Jodrell DI, Murphy G
    PLoS ONE, 2012;7(7):e40597.
    Species: Human
    Sample Types: Tissue Homogenates
  204. Age-related changes in expression and function of Toll-like receptors in human skin.
    Authors: Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schoppl A, Tschachler E, Elbe-Burger A
    Development, 2012;139(22):4210-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  205. Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti.
    Authors: Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A
    PLoS Negl Trop Dis, 2012;6(4):e1611.
    Species: Human
    Sample Types: Cell Culture Supernates
  206. Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
    Eur J Clin Nutr, 2012;66(9):1072-4.
    Species: Human
    Sample Types: Plasma
  207. TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.
    Authors: Jouan-Lanhouet S, Arshad M, Piquet-Pellorce C, Martin-Chouly C, Le Moigne-Muller G, Van Herreweghe F, Takahashi N, Sergent O, Lagadic-Gossmann D, Vandenabeele P, Samson M, Dimanche-Boitrel M
    Cell Death Differ, 2012;19(12):2003-14.
    Species: Human
    Sample Types: Cell Culture Supernates
  208. Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
    J Neuroinflammation, 2012;9(0):203.
    Species: Human
    Sample Types: Cell Culture Supernates
  209. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
    Authors: Suh HS, Choi N, Tarassishin L, Lee SC
    PLoS ONE, 2012;7(4):e35115.
    Species: Human
    Sample Types: Cell Culture Supernates
  210. Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
    Authors: Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogne M, Moura IC, Monteiro RC
    J. Exp. Med., 2012;209(4):793-806.
    Species: Human
    Sample Types: Cell Culture Supernates
  211. Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.
    Authors: Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL
    PLoS ONE, 2012;7(4):e35866.
    Species: Human
    Sample Types: Cell Culture Supernates
  212. Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
    Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
    Blood, 2011;118(8):2366-74.
    Species: Human
    Sample Types: Cell Lysates
  213. Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques.
    Authors: Clauser S, Meilhac O, Bieche I, Raynal P, Bruneval P, Michel JB, Borgel D
    Thromb. Haemost., 2011;107(1):140-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  214. Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma.
    Authors: Leivo-Korpela S, Lehtimaki L, Vuolteenaho K, Nieminen R, Kankaanranta H, Saarelainen S, Moilanen E
    J Inflamm (Lond), 2011;8(0):12.
    Species: Human
    Sample Types: Cell Culture Supernates
  215. Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients.
    Authors: Neuenschwander LC, Bittencourt H, Ribeiro AF, Teixeira AL, Teixeira MM, Teixeira JC, Nobre V
    Clinics (Sao Paulo), 2011;66(10):1699-705.
    Species: Human
    Sample Types: Plasma
  216. Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
    Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
    Blood, 2011;118(18):5031-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  217. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
    Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Immunol., 2010;184(9):4880-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  218. Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis.
    Authors: Rodland EK, Ueland T, Pedersen TM, Halvorsen B, Muller F, Aukrust P, Froland SS
    Infect. Immun., 2010;78(3):1269-75.
    Species: Human
    Sample Types: Cell Culture Supernates
  219. KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.
    Authors: Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst J, Gibbs A, Kahl J, Kessler L, Lundstrom J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ
    Eur. J. Pharmacol., 2010;632(1):93-102.
    Species: Human
    Sample Types: Cell Culture Supernates
  220. Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
    Authors: van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, Van der Meer JW, Netea MG
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3030-3.
    Species: Human
    Sample Types: Cell Culture Supernates
  221. The role of RGD-tagged helical rosette nanotubes in the induction of inflammation and apoptosis in human lung adenocarcinoma cells through the P38 MAPK pathway.
    Authors: Suri SS, Rakotondradany F, Myles AJ, Fenniri H, Singh B
    Biomaterials, 2009;30(17):3084-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  222. Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
    Authors: Correale J, Farez M
    J. Immunol., 2009;183(9):5999-6012.
    Species: Human
    Sample Types: Cell Culture Supernates
  223. Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.
    Authors: Huang QQ, Sobkoviak R, Jockheck-Clark AR, Shi B, Mandelin AM, Tak PP, Haines GK, Nicchitta CV, Pope RM
    J. Immunol., 2009;182(8):4965-73.
    Species: Human
    Sample Types: Cell Culture Supernates
  224. Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
    Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
    Clin. Immunol., 2009;133(1):27-44.
    Species: Human
    Sample Types: Plasma
  225. Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
    Authors: Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, Orinska Z, Paus R, Bulfone-Paus S, Giovarelli M
    J. Immunol., 2009;183(5):3004-13.
    Species: Human
    Sample Types: Cell Culture Supernates
  226. Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.
    Authors: Damsgaard CT, Lauritzen L, Calder PC, Kjaer TR, Frokiaer H
    J. Nutr., 2009;139(7):1410-4.
    Species: Human
    Sample Types: Cell Culture Supernates
  227. Helminth infections associated with multiple sclerosis induce regulatory B cells.
    Authors: Correale J, Farez M, Razzitte G
    Ann. Neurol., 2008;64(2):187-99.
    Species: Human
    Sample Types: Cell Culture Supernates
  228. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
    Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
    J. Cell. Physiol., 2008;214(1):27-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  229. Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
    Authors: Lemarie A, Bourdonnay E, Morzadec C, Fardel O, Vernhet L
    J. Immunol., 2008;180(9):6010-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  230. Divergent effects of hypoxia on dendritic cell functions.
    Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
    Blood, 2008;112(9):3723-34.
    Species: Human
    Sample Types: Cell Culture Supernates
  231. Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
    Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
    J. Immunol., 2008;180(9):6000-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  232. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
    Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
    J. Biol. Chem., 2007;282(44):31882-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  233. The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation.
    Authors: Matalka KZ, Ali D, Khawad AE, Qa'dan F
    Cytokine, 2007;40(3):235-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  234. Cytokine response to strenuous exercise in athletes and non-athletes--an adaptive response.
    Authors: Gokhale R, Chandrashekara S, Vasanthakumar KC
    Cytokine, 2007;40(2):123-7.
    Species: Human
    Sample Types: Plasma
  235. Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor.
    Authors: Skibinski G, Elborn JS, Ennis M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(1):L69-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  236. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.
    Authors: Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;292(2):L567-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  237. Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors.
    Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H
    Cytokine, 2007;34(5):278-83.
    Species: Human
    Sample Types: Serum
  238. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007;117(12):3664-3672.
    Species: Human
    Sample Types: Cell Culture Supernates
  239. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.
    Authors: Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P
    Blood, 2007;110(13):4319-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  240. Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
    Authors: Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA
    Am. J. Respir. Crit. Care Med., 2006;173(9):1038-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  241. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006;176(6):3742-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  242. The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity.
    Authors: Lauzon NM, Mian F, MacKenzie R, Ashkar AA
    Cell. Immunol., 2006;241(2):102-12.
    Species: Human
    Sample Types: Cell Culture Supernates
  243. A combination of E. coli DNA fragments and modified lipopolysaccharides as a cancer immunotherapy.
    Authors: Cho YJ, Ahn BY, Lee NG, Lee DH, Kim DS
    Vaccine, 2006;24(31):5862-71.
    Species: Human
    Sample Types: Cell Culture Supernates
  244. Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation.
    Authors: Smith EL, Finney HM, Nesbitt AM, Ramsdell F, Robinson MK
    Immunology, 2006;119(2):203-11.
    Species: Human
    Sample Types: Cell Culture Supernates
  245. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
    Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
    J. Pharmacol. Exp. Ther., 2006;318(2):741-50.
    Species: Human
    Sample Types: Cell Culture Supernates
  246. A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression.
    Authors: Macagno A, Molteni M, Rinaldi A
    J. Exp. Med., 2006;203(6):1481-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  247. Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome.
    Authors: Liu JM, Zhu Y, Xu ZW, Ouyang WM, Wang JP, Liu XS, Cao YX, Li Q, Fang L, Zhuang R, Yang AG, Jin BQ
    Clin. Immunol., 2006;119(3):245-51.
    Species: Human
    Sample Types: Plasma
  248. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
    Authors: Pound JD, Batth BK, Johannessen I, Wood K
    J. Immunol., 2005;174(5):3015-23.
    Species: Human
    Sample Types: Cell Culture Supernates
  249. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
    Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
    Eur. J. Immunol., 2005;35(8):2459-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  250. Microbial exposure, symptoms and inflammatory mediators in nasal lavage fluid of kitchen and clerical personnel in schools.
    Authors: Lignell U, Meklin T, Putus T, Vepsalainen A, Roponen M, Torvinen E, Reeslev M, Pennanen S, Hirvonen MR, Kalliokoski P, Nevalainen A
    Int J Occup Med Environ Health, 2005;18(2):139-50.
    Species: Human
    Sample Types: Nasal Lavage Fluid
  251. The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model.
    Authors: Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A
    J. Immunol., 2004;172(10):6080-6.
    Species: Human
    Sample Types: Cell Culture Supernates
  252. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
    Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
    J. Immunol., 2004;173(2):1463-76.
    Species: Human
    Sample Types: Cell Culture Supernates
  253. Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
    Authors: Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT
    J. Biol. Chem., 2004;279(52):54405-15.
    Species: Human
    Sample Types: Cell Culture Supernates
  254. Association of type 2 cytokines with hepatic fibrosis in human Schistosoma mansoni infection.
    Authors: de Jesus AR, Magalhaes A, Miranda DG, Miranda RG, Araujo MI, de Jesus AA, Silva A, Santana LB, Pearce E, Carvalho EM
    Infect. Immun., 2004;72(6):3391-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  255. Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain.
    Authors: Finney HM, Akbar AN, Lawson AD
    J. Immunol., 2004;172(1):104-13.
    Species: Human
    Sample Types: Cell Culture Supernates
  256. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis.
    Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T
    Proc. Natl. Acad. Sci. U.S.A., 2003;100(16):9452-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  257. Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes.
    Authors: Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H
    Inhal Toxicol, 2002;14(6):653-62.
    Species: Human
    Sample Types: Sputum
  258. Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
    Authors: Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR
    Eur. Respir. J., 2001;18(3):542-8.
    Species: Human
    Sample Types: Serum
  259. Reproducibility of measurements of exhaled NO, and cell count and cytokine concentrations in induced sputum.
    Authors: Purokivi M, Randell J, Hirvonen MR, Tukiainen H
    Eur. Respir. J., 2000;16(2):242-6.
    Species: Human
    Sample Types: Sputum
  260. Effects of a short-course of amoxicillin/clavulanic acid on systemic and mucosal immunity in healthy adult humans.
    Authors: Dufour V, Millon L, Faucher JF, Bard E, Robinet E, Piarroux R, Vuitton DA, Meillet D
    Int. Immunopharmacol., 205;5(5):917-28.
    Species: Human
    Sample Types: Feces
  261. Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation.
    Authors: Guedan S, Posey A, Shaw C, Wing A, Da T, Patel P, McGettigan S, Casado-Medrano V, Kawalekar O, Uribe-Herranz M, Song D, Melenhorst J, Lacey S, Scholler J, Keith B, Young R, June C
    JCI Insight, 0;3(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  262. Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1.
    Authors: Wang R, Jaw JJ, Jaw J, Stutzman N, Stutzman NC, Zou Z, Sun PD
    J Leukoc Biol, 0;91(2):299-309.
    Species: Human
    Sample Types: Cell Culture Supernates
  263. Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk.
    Authors: LeBouder E, Rey-Nores J, Rushmere N, Grigorov M, Lawn S, Affolter M, Griffin G, Ferrara P, Schiffrin E, Morgan B, Labeta M
    J Immunol, 0;171(12):6680-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  264. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
    Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
    Mucosal Immunol, 0;5(2):140-9.
    Species: Human
    Sample Types: Cell Culture Supernates

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Human TNF-alpha DuoSet ELISA
By Anonymous on 03/24/2021
Application: Sample Tested: THP-1 cell supernatant

24-hour stimulation of THP-1 cells to rotenone with or without TLR inhibitor

R-squared value of 0.98 using sigmoidal 4-parameter logistic plot

Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 03/24/2021
Application: Sample Tested: Cell culture supernatant
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 03/22/2021
Application: Sample Tested: human macrophages
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 12/20/2020
Application: Sample Tested: human kidney tissue homogenate

TNFa was measured in the supernatant of human kidney tissue homogenate stimulated with LPS for 24 hours.

Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 12/20/2020
Application: Sample Tested: human monocyte-derived macrophages

This is a new lot of the Human TNF-alpha DuoSet ELISA kit. The results are reproducible and the quality of the kit consistent. Monocyte-derived human macrophages were treated with 20 μg/ml zymosan for 24 hours and TNFa was assessed in the supernatant.

Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 11/28/2020
Application: Sample Tested: Monocyte-derived dendritic cells

TNFa secretion was measured in the supernatant of LPS-stimulated (100 ng/ml) cultured human dendritic cells after 18 hours.

Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 10/13/2020
Application: Sample Tested: Monocytes

Monocytes were stimulated with LPS (100 ng/ml) for 24 hours. After 24 hours, TNFa was assessed in the supernatant.

Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 08/11/2020
Application: Sample Tested: Serum and Plasma
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 02/11/2020
Application: Sample Tested: K562 human chronic myelogenous leukemia cell line
Human TNF-alpha DuoSet ELISA
By Anonymous on 01/15/2020
Application: Sample Tested: Cell culture supernatant
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 11/04/2019
Application: Sample Tested: Monocytes
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 08/08/2019
Application: Sample Tested: Peripheral blood monocytes

TNFa levels in PBM supernatants after dIgG treatment.

Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 01/03/2019
Application: Sample Tested: Cell Lysates
Human TNF-alpha DuoSet ELISA
By Anonymous on 01/03/2019
Application: Sample Tested: Cell culture supernatant
Human TNF-alpha DuoSet ELISA
By Anonymous on 10/08/2018
Application: Sample Tested: EDTA Plasma
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 09/11/2018
Application: Sample Tested: Purified Standard
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 03/30/2018
Application: Sample Tested: Serum
Human TNF-alpha DuoSet ELISA
By Anonymous on 01/25/2018
Application: Sample Tested: Cell Culture Media
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 01/18/2018
Application: Sample Tested: EDTA Plasma
Human TNF-alpha DuoSet ELISA
By Anonymous on 12/18/2017
Application: Sample Tested: Peripheral blood mononuclear cells (PBMCs)
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 12/15/2017
Application: Sample Tested: human sera
Human TNF-alpha DuoSet ELISA
By Anonymous on 10/17/2017
Application: Sample Tested: U937 human histiocytic lymphoma cell line
Serum Human TNF-alpha DuoSet ELISA DY210
Human TNF-alpha DuoSet ELISA
By Anonymous on 06/13/2017
Application: Sample Tested: human serum
Serum Human TNF-alpha DuoSet ELISA DY210