Human UGRP1/SCGB3A2 Antibody

Catalog # Availability Size / Price Qty
AF3545
AF3545-SP
Product Details
Citations (2)
FAQs
Supplemental Products
Reviews (1)

Human UGRP1/SCGB3A2 Antibody Summary

Species Reactivity
Human
Specificity
Detects human UGRP1/SCGB3A2 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant mouse UGRP1 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human UGRP1/SCGB3A2
Phe22-Val93
Accession # Q96PL1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human UGRP1/SCGB3A2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: UGRP1/SCGB3A2

UGRP-1, also known as secretoglobin family 3A member 2 (SCGB3A2) and High in Normal 2 (HIN-2), is a secreted, 38 kDa, homodimeric protein that is highly expressed in epithelial cells of the airway. UGRP-1 has been shown to bind MARCO (macrophage scavenger receptor with collagenous structure), which is expressed by alveolar macrophages. UGRP1 has been suggested to play a role in lung inflammation. Mature human UGRP1 shares 88% and 81% amino acid sequence identity with rat and mouse mature UGRP1, respectively. Mature UGRP-1 is also 53% identical with that of human mature UGRP-2 (HIN-1).

Long Name
Uteroglobin-related Protein 1
Entrez Gene IDs
117156 (Human); 117158 (Mouse)
Alternate Names
LU103; Pneumo secretory protein 1; PnSP-1; PNSP1secretoglobin family 3A member 2; SCGB3A2; secretoglobin, family 3A, member 2; UGRP1; UGRP1pnSP-1; Uteroglobin-related protein 1

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Citations for Human UGRP1/SCGB3A2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
    Authors: P Kadur Laks, V Sontake, A Tata, Y Kobayashi, L Macadlo, K Okuda, AS Conchola, S Nakano, S Gregory, LA Miller, JR Spence, JF Engelhardt, RC Boucher, JR Rock, SH Randell, PR Tata
    Nature, 2022-03-30;604(7904):111-119.
  2. An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells
    Authors: Mart M Lamers, Jelte van der Vaart, Kèvin Knoops, Samra Riesebosch, Tim I Breugem, Anna Z Mykytyn et al.
    The EMBO Journal

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Reviews for Human UGRP1/SCGB3A2 Antibody

Average Rating: 5 (Based on 1 Review)

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Human UGRP1/SCGB3A2 Antibody
By Anonymous on 01/25/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: human lung Species: Human