IKK gamma [p Ser376] Antibody

Name: IKK gamma [p Ser376] Antibody
Brand: Novus Biologicals
SKU: NBP3-13396
Price: 489 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-13396

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide surrounding phospho Ser376 of human IKK gamma. The exact sequence is proprietary.

Modification

p Ser 376

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for IKK gamma [p Ser376] Antibody

Western Blot: IKK gamma [p Ser376] Antibody [NBP3-13396]

Western Blot: IKK gamma [p Ser376] Antibody [NBP3-13396] - Untreated (-) and treated (+) HeLa whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with IKK gamma (phospho Ser376) antibody (NBP3-13396) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Immunohistochemistry-Paraffin: IKK gamma [p Ser376] Antibody [NBP3-13396]

Immunohistochemistry-Paraffin: IKK gamma [p Ser376] Antibody [NBP3-13396] - IKK gamma (phospho Ser376) antibody detects IKK gamma (phospho Ser376) protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. IKK gamma (phospho Ser376) stained by IKK gamma (phospho Ser376) antibody (NBP3-13396) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for IKK gamma [p Ser376] Antibody

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IKK gamma

Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males (The International Incontinentia Pigmenti Consortium, 2000 [PubMed 10839543]). In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito (MIM 300337).[supplied by OMIM]

Long Name

IkB Kinase gamma

Alternate Names

FIP3P, IKBKG, IKKAP1, NEMO

Gene Symbol

IKBKG

Additional IKK gamma Products

Product Documents for IKK gamma [p Ser376] Antibody

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Certificate of Analysis

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Product Specific Notices for IKK gamma [p Ser376] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.