IL-4 Antibody (286120) [DyLight 405]

Name: IL-4 Antibody (286120) [DyLight 405]
Brand: Novus Biologicals
SKU: FAB6542E
Price: 499 USD
Availability: InStock

Novus Biologicals | Catalog # FAB6542E

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Porcine

Applications

Neutralization

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # 286120

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Product Specifications

Immunogen

E. coli-derived recombinant porcine IL-4
His25-Cys133
Accession # Q04745

Specificity

Detects porcine IL-4 in Western blots. In Western blots, 100% cross-reactivity with recombinant mouse IL-4 is observed, 15% with recombinant rat IL-4 is observed, and no cross-reactivity with recombinant bovine IL-4, recombinant canine IL-4, recombinant cotton rat IL-4, recombinant equine IL-4, recombinant feline IL-4, recombinant human IL-4, or recombinant human IL-13 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for IL-4 Antibody (286120) [DyLight 405]

Application

Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-4

IL-4 (Interleukin 4, B cell stimulatory factor) is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. IL-4 has many different functions including promoting proliferation and differentiation of immunologically competent cells. One of its main functions is regulating differentiation of naive CD4+ T cells into helper Th2 cells, the other main function is regulating B cells IgE and IgG1 production. Human IL-4 shows 50% homology with mouse IL-4, but its activities are species-specific and human IL-4 shows no activity on murine and rat cells.

Long Name

Interleukin 4

Alternate Names

BCDF, BCGF-1, BCGF1, BSF-1, BSF1, IL4, IL4E12

Gene Symbol

IL4

Additional IL-4 Products

Product Documents for IL-4 Antibody (286120) [DyLight 405]

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Certificate of Analysis

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Product Specific Notices for IL-4 Antibody (286120) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.