Mouse IFN-alpha ELISA Kit

Catalog # Availability Size / Price Qty
42120-1
42120-2
Product Details
Citations (17)
FAQs
Supplemental Products
Reviews (1)

Mouse IFN-alpha ELISA Kit Summary

Assay Length
27.25 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL)
Sensitivity
12.5 pg/mL
Assay Range
12.5 - 400 pg/mL (Cell Culture Supernates)
Specificity
Mouse IFN-alpha
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

Product Datasheets

Preparation and Storage

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name:
Interferon alpha
Entrez Gene IDs:
3440 (Human)
Alternate Names:
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2

Citations for Mouse IFN-alpha ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

17 Citations: Showing 1 - 10
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  1. Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses
    Authors: YW Lin, LC Wang, CK Lee, SH Chen
    Sci Rep, 2018;8(1):12184.
    Species: Mouse
    Sample Types: Tissue Lysates
  2. The Essential Role of Double-Stranded RNA-Dependent Antiviral Signaling in the Degradation of Nonself Single-Stranded RNA in Nonimmune Cells
    Authors: S Kimura, T Matsumiya, Y Shiba, M Nakanishi, R Hayakari, S Kawaguchi, H Yoshida, T Imaizumi
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  3. TRAIL signaling is pro-inflammatory and pro-viral in a murine model of rhinovirus 1B infection
    Authors: Joerg Mattes
    Am. J. Physiol. Lung Cell Mol. Physiol., 2016;0(0):ajplung.00200.
    Species: Mouse
    Sample Types: Tissue Homogenates
  4. WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
    Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
    BMC Gastroenterol, 2015;15(0):173.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  5. DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
    Authors: Chan, Mei Po, Onji, Masahiro, Fukui, Ryutaro, Kawane, Kohki, Shibata, Takuma, Saitoh, Shin-ich, Ohto, Umeharu, Shimizu, Toshiyuk, Barber, Glen N, Miyake, Kensuke
    Nat Commun, 2015;6(0):5853.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
    Authors: Dulek D, Newcomb D, Toki S, Goliniewska K, Cephus J, Reiss S, Bates J, Crowe J, Boyd K, Moore M, Zhou W, Peebles R
    J Virol, 2014;88(17):9655-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  7. Activation of A1-adenosine receptors promotes leukocyte recruitment to the lung and attenuates acute lung injury in mice infected with influenza A/WSN/33 (H1N1) virus.
    Authors: Aeffner F, Woods P, Davis I
    J Virol, 2014;88(17):10214-27.
    Species: Mouse
    Sample Types: BALF
  8. IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection.
    Authors: Jayaraman A, Jackson D, Message S, Pearson R, Aniscenko J, Caramori G, Mallia P, Papi A, Shamji B, Edwards M, Westwick J, Hansel T, Stanciu L, Johnston S, Bartlett N
    Mucosal Immunol, 2014;7(5):1151-64.
    Species: Mouse
    Sample Types: BALF
  9. Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction.
    Authors: Desch, A Nicole, Gibbings, Sophie L, Clambey, Eric T, Janssen, William, Slansky, Jill E, Kedl, Ross M, Henson, Peter M, Jakubzick, Claudia
    Nat Commun, 2014;5(0):4674.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  10. Recombinant human interferon alpha 2b prevents and reverses experimental pulmonary hypertension.
    Authors: Bauer E, Zheng H, Lotze M, Bauer P
    PLoS ONE, 2014;9(5):e96720.
    Species: Mouse
    Sample Types: Serum
  11. Plasminogen controls inflammation and pathogenesis of influenza virus infections via fibrinolysis.
    Authors: Berri F, Rimmelzwaan G, Hanss M, Albina E, Foucault-Grunenwald M, Le V, Vogelzang-van Trierum S, Gil P, Camerer E, Martinez D, Lina B, Lijnen R, Carmeliet P, Riteau B
    PLoS Pathog, 2013;9(3):e1003229.
    Species: Mouse
    Sample Types: BALF
  12. Modulation of dendritic cell function and immune response by cysteine protease inhibitor from murine nematode parasite Heligmosomoides polygyrus.
    Authors: Sun Y, Liu G, Li Z, Chen Y, Liu Y, Liu B, Su Z
    Immunology, 2013;138(4):370-81.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
    Authors: Walsh KB, Teijaro JR, Wilker PR
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23.
    Species: Mouse
    Sample Types: BALF
  14. The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
    Authors: Vultaggio A, Nencini F, Pratesi S, Maggi L, Guarna A, Annunziato F, Romagnani S, Parronchi P, Maggi E
    J. Immunol., 2011;186(8):4707-15.
    Species: Mouse
    Sample Types: Serum
  15. ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.
    Authors: Bondue B, Vosters O, de Nadai P, Glineur S, De Henau O, Luangsay S, Van Gool F, Communi D, De Vuyst P, Desmecht D, Parmentier M
    PLoS Pathog., 2011;7(11):e1002358.
    Species: Mouse
    Sample Types: Tissue Homogenates
  16. Selective induction of host genes by MVA-B, a candidate vaccine against HIV/AIDS.
    Authors: Guerra S, Gonzalez JM, Climent N, Reyburn H, Lopez-Fernandez LA, Najera JL, Gomez CE, Garcia F, Gatell JM, Gallart T, Esteban M
    J. Virol., 2010;84(16):8141-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  17. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo.
    Authors: Qin L, Greenland JR, Moriya C
    J. Virol., 2007;81(19):10606-13.
    Species: Mouse
    Sample Types: Tissue Homogenates

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Mouse IFN-alpha ELISA Kit
By Anonymous on 07/13/2016
Sample Tested: Cell culture supernatant