Mouse IFN-gamma Quantikine ELISA Kit

  (180 citations)
(5 Reviews)
    
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Product Details
Assay Procedure
Citations (180)
FAQs
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Reviews
  • Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Serum (50 uL)
  • Sensitivity
    2 pg/mL
  • Assay Range
    9.4 - 600 pg/mL (Cell Culture Supernates, Serum)
  • Specificity
    Natural and recombinant mouse IFN-gamma
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Product Summary
The Quantikine Mouse IFN-gamma Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IFN-gamma in cell culture supernates and mouse serum. It contains E. coli-expressed mouse IFN-gamma and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant mouse IFN-gamma accurately. Results obtained using natural mouse IFN-gamma showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IFN-gamma.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 44.8 156 518 43.3 144 509
Standard Deviation 2.2 5 14.2 3.6 14.7 48.6
CV% 4.9 3.2 2.7 8.3 10.2 9.5

Serum
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 45.1 143 528 42.8 139 518
Standard Deviation 2.1 4.4 11.8 3.6 13.6 46.5
CV% 4.7 3.1 2.2 8.4 9.8 9

Recovery

The recovery of mouse IFN-gamma spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=7) 105 98-115
Serum (n=5) 97 91-106
Linearity
To assess the linearity of the assay, five or more samples containing and/or spiked with various concentrations of mouse IFN-gamma in each matrix were diluted with the appropriate Calibrator Diluent and then assayed.
 IFN-gamma [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: IFN-gamma
IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
  • Long Name:
    Interferon gamma
  • Entrez Gene IDs:
    3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline)
  • Alternate Names:
    IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma
Related Research Areas
Assay Procedure
Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Assay Diluent
  4.   Add 50 µL of Assay Diluent to each well.

  5. 50 µL Standard, Control, or Sample
  6.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.

  8. 100 µL Conjugate
  9.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 5 times.

  11. 100 µL Substrate Solution
  12.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  13. 100 µL Stop Solution
  14.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

180 Citations: Showing 1 - 10
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Species
Sample Type
  1. Murine ?-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27-Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin
    Authors: K Kanai, AM Park, A Watanabe, T Arikawa, T Yasui, H Yoshida, I Tsunoda, O Yoshie
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Type: BALF
  2. Transfection of bone marrow derived cells with immunoregulatory proteins
    Authors: JN Khantakova, AN Silkov, VP Tereshchen, EV Gavrilova, RA Maksyutov, SV Sennikov
    Cytokine, 2018;108(0):82-88.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  3. Immune Regulation of Intrahepatic Regulatory T Cells in Fibrotic Livers of Mice
    Authors: X Zhang, J Lou, L Bai, Y Chen, S Zheng, Z Duan
    Med. Sci. Monit, 2017;23(0):1009-1016.
    Species: Mouse
    Sample Type: Serum
  4. Cutting Edge: Innate Immune Augmenting Vesicular Stomatitis Virus Expressing Zika Virus Proteins Confers Protective Immunity
    Authors: D Betancourt, NM de Queiroz, T Xia, J Ahn, GN Barber
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  5. Efficacy of Juzentaihoto for Tumor Immunotherapy in B16 Melanoma Metastasis Model
    Authors: S Ishikawa, T Ishikawa, C Tezuka, K Asano, M Sunagawa, T Hisamitsu
    Evid Based Complement Alternat Med, 2017;2017(0):6054706.
    Species: Mouse
    Sample Type: Serum
  6. Host resistance to Plasmodium-induced acute immune pathology is regulated by IL-10 receptor signalling
    Authors: C Claser, JB De Souza, SG Thorburn, GE Grau, EM Riley, L Rénia, JC Hafalla
    Infect. Immun., 2017;0(0):.
    Species: Mouse
    Sample Type: Serum
  7. Induction and characterization of anti-tumor endothelium immunity elicited by ValloVax therapeutic cancer vaccine
    Authors: SC Wagner, TE Ichim, V Bogin, WP Min, F Silva, AN Patel, S Kesari
    Oncotarget, 2017;8(17):28595-28613.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  8. Anti-CD20 monoclonal antibody combined with adenovirus vector-mediated IL-10 regulates spleen CD4+/CD8+ T�cells and T-bet/GATA-3 expression in NOD mice
    Authors: A Tang, C Li, Z Chen, T Li
    Mol Med Rep, 2017;0(0):.
    Species: Mouse
    Sample Type: Serum
  9. Fungal immunomodulatory protein-fve could modulate airway remodel through by affect IL17 cytokine
    Authors: YT Lee, CT Wu, HL Sun, JL Ko, KH Lue
    J Microbiol Immunol Infect, 2017;0(0):.
    Species: Mouse
    Sample Type: BALF
  10. Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function
    Authors: T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  11. Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma
    Authors: U Lampreht T, L Loiacono, M Cemazar, U Kamensek, VM Fazio, G Sersa, E Signori
    Mediators Inflamm., 2017;2017(0):5285890.
    Species: Mouse
    Sample Type: Serum
  12. Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
    Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
    Sci Rep, 2017;7(1):3957.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  13. Effects of Gintonin-Enriched Fraction in an Atopic Dermatitis Animal Model: Involvement of Autotaxin Regulation
    Authors: BH Lee, HK Kim, M Jang, HJ Kim, SH Choi, SH Hwang, HC Kim, H Rhim, IH Cho, SY Nah
    Biol. Pharm. Bull., 2017;40(7):1063-1070.
    Species: Mouse
    Sample Type: Serum
  14. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice
    Authors: A Okumura, T Saito, M Tobiume, Y Hashimoto, Y Sato, T Umeyama, M Nagi, K Tanabe, H Unoki-Kubo, Y Kaburagi, H Hasegawa, Y Miyazaki, S Yamagoe
    Biochem Biophys Rep, 2017;12(0):166-171.
    Species: Mouse
    Sample Type: Serum
  15. Vaccination with the Secreted Glycoprotein G of Herpes Simplex Virus 2 Induces Protective Immunity after Genital Infection
    Authors: K Önnheim, M Ekblad, S Görander, T Bergström, JÅ Liljeqvist
    Viruses, 2016;8(4):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  16. Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections
    PLoS Pathog, 2016;12(4):e1005600.
    Species: Mouse
    Sample Type: Tissue Homogenates
  17. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
    Sci Rep, 2016;6(0):38438.
    Species: Mouse
    Sample Type: Serum
  18. Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
    Sci Rep, 2016;6(0):38387.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  19. In Vivo Expansion of Activated Foxp3+ Regulatory T Cells and Establishment of a Type 2 Immune Response upon IL-33 Treatment Protect against Experimental Arthritis
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  20. Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease.
    Authors: Bolz M, Kerber S, Zimmer G, Pluschke G
    PLoS Negl Trop Dis, 2015;9(8):e0004011.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  21. Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo.
    Authors: Kerbrat S, Vingert B, Junier M, Castellano F, Renault-Mihara F, Dos Reis Tavares S, Surenaud M, Noizat-Pirenne F, Boczkowski J, Guellaen G, Chneiweiss H, Le Gouvello S
    PLoS ONE, 2015;10(8):e0136885.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  22. WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
    Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
    BMC Gastroenterol, 2015;15(0):173.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  23. Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice.
    Authors: Alam I, Gray A, Acton D, Gerard-O'Riley R, Reilly A, Econs M
    J Bone Miner Res, 2015;30(11):2005-13.
    Species: Mouse
    Sample Type: Serum
  24. Propionibacterium acnes Augments Antitumor, Anti-Angiogenesis and Immunomodulatory Effects of Melatonin on Breast Cancer Implanted in Mice.
    Authors: Talib W, Saleh S
    PLoS ONE, 2015;10(4):e0124384.
    Species: Mouse
    Sample Type: Serum
  25. G-protein-coupled estrogen receptor agonist suppresses airway inflammation in a mouse model of asthma through IL-10.
    Authors: Itoga M, Konno Y, Moritoki Y, Saito Y, Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M
    PLoS ONE, 2015;10(3):e0123210.
    Species: Mouse
    Sample Type: BALF
  26. HGF Gene Modification in Mesenchymal Stem Cells Reduces Radiation-Induced Intestinal Injury by Modulating Immunity.
    Authors: Wang H, Sun R, Li Y, Yang Y, Xiao F, Zhang Y, Wang S, Sun H, Zhang Q, Wu C, Wang L
    PLoS ONE, 2015;10(5):e0124420.
    Species: Mouse
    Sample Type: Serum
  27. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.
    Authors: Basu R, Whitley S, Bhaumik S, Zindl C, Schoeb T, Benveniste E, Pear W, Hatton R, Weaver C
    Nat Immunol, 2015;16(3):286-95.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  28. Immunomodulator-based enhancement of anti smallpox immune responses.
    Authors: Martinez O, Miranda E, Ramirez M, Santos S, Rivera C, Vazquez L, Sanchez T, Tremblay R, Rios-Olivares E, Otero M
    PLoS ONE, 2015;10(4):e0123113.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  29. Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen.
    Authors: Ikezoe T, Yang J, Nishioka C, Yokoyama A
    Bone Marrow Transplant, 2015;50(1):113-20.
    Species: Mouse
    Sample Type: Plasma
  30. Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines.
    Authors: Lorenzo C, Perez-Chacon G, Garaulet G, Mallorquin Z, Zapata J, Rodriguez A
    Cancer Gene Ther, 2015;22(11):542-51.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  31. Modulation of recombinant antigenic constructs containing multi-epitopes towards effective reduction of atherosclerotic lesion in B6;129S-Ldlr(tm1Her)Apob(tm2Sgy)/J mice.
    Authors: Xia M, Chen D, Endresz V, Lantos I, Szabo A, Kakkar V, Lu X
    PLoS ONE, 2015;10(4):e0123393.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  32. Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.
    Authors: Mishra, Amarjit, Brown, Alexandr, Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep, McCoy, J Philip, Keeran, Karen J, Nugent, Gayle Z, Jeffries, Kenneth, Qu, Xuan, Yu, Zu-Xi, Levine, Stewart, Chung, Jay H
    Nat Commun, 2015;6(0):6224.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  33. IL-18 expression results in a recombinant vaccinia virus that is highly attenuated and immunogenic.
    Authors: Verardi P, Legrand F, Chan K, Peng Y, Jones L, Yilma T
    J Interferon Cytokine Res, 2014;34(3):169-78.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  34. Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma.
    Authors: Hu S, Rotschafer J, Lokensgard J, Cheeran M
    PLoS ONE, 2014;9(8):e105219.
    Species: Mouse
    Sample Type: Whole Cells
  35. Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response.
    Authors: Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, Ukil A
    FASEB J, 2014;28(4):1756-68.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  36. Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer.
    Authors: Goshima F, Esaki S, Luo C, Kamakura M, Kimura H, Nishiyama Y
    Int J Cancer, 2014;134(12):2865-77.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  37. Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.
    Authors: Ratnoglik S, Jiang D, Aoki C, Sudarmono P, Shoji I, Deng L, Hotta H
    PLoS ONE, 2014;9(6):e98877.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  38. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
    Authors: Yamane, Kazuhiko, Indalao, Irene L, Chida, Junji, Yamamoto, Yoshikaz, Hanawa, Masaaki, Kido, Hiroshi
    PLoS ONE, 2014;9(5):e98032.
    Species: Mouse
    Sample Type: Tissue Homogenates
  39. ASK1 promotes the contact hypersensitivity response through IL-17 production.
    Authors: Mizukami J, Sato T, Camps M, Ji H, Rueckle T, Swinnen D, Tsuboi R, Takeda K, Ichijo H
    Sci Rep, 2014;4(0):4714.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  40. Sindbis viral vectors transiently deliver tumor-associated antigens to lymph nodes and elicit diversified antitumor CD8+ T-cell immunity.
    Authors: Granot, Tomer, Yamanashi, Yoshihid, Meruelo, Daniel
    Mol Ther, 2014;22(1):112-22.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  41. PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer.
    Authors: Guo Z, Wang X, Cheng D, Xia Z, Luan M, Zhang S
    PLoS ONE, 2014;9(2):e89350.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  42. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
    Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
    J Immunol, 2014;192(8):3569-81.
    Species: Mouse
    Sample Type: Whole Tissue
  43. Genetic vaccine for respiratory syncytial virus provides protection without disease potentiation.
    Authors: Johnson T, Rangel D, Graham B, Brough D, Gall J
    Mol Ther, 2014;22(1):196-205.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  44. Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs.
    Authors: Lu L, Xu X, Zhang B, Zhang R, Ji H, Wang X
    J Transl Med, 2014;12(0):36.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  45. Antibody to mCLCA3 suppresses symptoms in a mouse model of asthma.
    Authors: Song L, Liu D, Wu C, Wu S, Yang J, Ren F, Li Y
    PLoS ONE, 2013;8(12):e82367.
    Species: Mouse
    Sample Type: BALF
  46. Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
    Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
    J Biol Chem, 2013;288(18):12699-711.
    Species: Mouse
    Sample Type: Tissue Homogenates
  47. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim, Janice J, Bridle, Byram W, Ghia, Jean-Eri, Wang, Huaqing, Syed, Shahzad, Manocha, Marcus M, Rengasamy, Palanive, Shajib, Mohammad, Wan, Yonghong, Hedlund, Peter B, Khan, Waliul I
    J Immunol, 2013;190(9):4795-804.
    Species: Mouse
    Sample Type: Tissue Homogenates
  48. TLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis.
    Authors: Chattoraj P, Yang Q, Khandai A, Al-Hendy O, Ismail N
    PLoS ONE, 2013;8(3):e58514.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  49. Combinatorial PD-1 blockade and CD137 activation has therapeutic efficacy in murine cancer models and synergizes with cisplatin.
    Authors: Wei H, Zhao L, Li W, Fan K, Qian W, Hou S, Wang H, Dai M, Hellstrom I, Hellstrom K, Guo Y
    PLoS ONE, 2013;8(12):e84927.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  50. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012;7(1):e30005.
    Species: Mouse
    Sample Type: Tissue Homogenates
  51. Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
    Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
    J. Biol. Chem., 2012;287(20):16356-64.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  52. Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands.
    Authors: Munich S, Sobo-Vujanovic A, Buchser W, Beer-Stolz D, Vujanovic N
    Oncoimmunology, 2012;1(7):1074-1083.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  53. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
    Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
    Am. J. Pathol., 2012;179(1):302-14.
    Species: Mouse
    Sample Type: Tissue Homogenates
  54. The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi.
    Authors: Calderon J, Maganto-Garcia E, Punzon C, Carrion J, Terhorst C, Fresno M
    PLoS Pathog., 2012;8(7):e1002799.
    Species: Mouse
    Sample Type: Serum
  55. Crawling Phagocytes Recruited in the Brain Vasculature after Pertussis Toxin Exposure through IL6, ICAM1 and ITGalphaM.
    Authors: Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L
    Brain Pathol., 2011;21(0):661.
    Species: Mouse
    Sample Type: Serum
  56. Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke.
    Authors: Liesz A, Zhou W, Mracsko É, Karcher S, Bauer H, Schwarting S, Sun L, Bruder D, Stegemann S, Cerwenka A, Sommer C, Dalpke AH, Veltkamp R
    Brain, 2011;134(0):704-20.
    Species: Mouse
    Sample Type: Serum
  57. The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.
    Authors: Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N
    J. Immunol., 2011;187(3):1333-46.
    Species: Mouse
    Sample Type: Serum
  58. IL-33-activated dendritic cells are critical for allergic airway inflammation.
    Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
    Eur. J. Immunol., 2011;41(6):1675-86.
    Species: Mouse
    Sample Type: BALF
  59. hsBAFF regulates proliferation and response in cultured CD4(+) T lymphocytes by upregulation of intracellular free Ca(2+) homeostasis.
    Authors: Wen L, Chen SJ, Zhang W, Ma HW, Zhang SQ, Chen L
    Cytokine, 2011;53(2):215-22.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  60. Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma.
    Authors: Hirata H, Arima M, Fukushima Y, Honda K, Sugiyama K, Tokuhisa T, Fukuda T
    Clin. Exp. Allergy, 2011;41(8):1133-42.
    Species: Mouse
    Sample Type: BALF
  61. Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.
    Authors: Otte A, Sauter M, Alleva L, Baumgarte S, Klingel K, Gabriel G
    Am. J. Pathol., 2011;179(1):230-9.
    Species: Mouse
    Sample Type: Serum
  62. Control of mouse graft-versus-host disease following allogeneic bone marrow transplantation by blocking the CD28/B7 signaling pathway with lentiviral vector-mediated RNA interference.
    Authors: Sang W, Zhou C, Cheng N, Li Z, Zeng L, Xu K
    Immunol. Lett., 2011;136(2):194-202.
    Species: Mouse
    Sample Type: Plasma
  63. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence.
    Authors: Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI
    J. Immunol., 2011;186(5):2826-34.
    Species: Mouse
    Sample Type: Plasma
  64. IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs.
    Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H
    J. Immunol., 2011;188(3):1503-13.
    Species: Mouse
    Sample Type: BALF
  65. Origination of new immunological functions in the costimulatory molecule B7-H3: the role of exon duplication in evolution of the immune system.
    Authors: Sun J, Fu F, Gu W, Yan R, Zhang G, Shen Z, Zhou Y, Wang H, Shen B, Zhang X
    PLoS ONE, 2011;6(9):e24751.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  66. The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
    Authors: Vultaggio A, Nencini F, Pratesi S, Maggi L, Guarna A, Annunziato F, Romagnani S, Parronchi P, Maggi E
    J. Immunol., 2011;186(8):4707-15.
    Species: Mouse
    Sample Type: Serum
  67. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011;178(2):662-71.
  68. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
    Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
    J. Immunol., 2010;185(4):2044-50.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  69. IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.
    Authors: Unsinger J, McGlynn M, Kasten KR, Hoekzema AS, Watanabe E, Muenzer JT, McDonough JS, Tschoep J, Ferguson TA, McDunn JE, Morre M, Hildeman DA, Caldwell CC, Hotchkiss RS
    J. Immunol., 2010;184(7):3768-79.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  70. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010;185(4):2502-15.
    Species: Mouse
    Sample Type: Serum
  71. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
    Authors: Pini M, Fantuzzi G
    J. Leukoc. Biol., 2010;87(1):51-8.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  72. Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
    Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L67-78.
    Species: Mouse
    Sample Type: BALF
  73. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site.
    Authors: Tan C, Aziz MK, Lovaas JD, Vistica BP, Shi G, Wawrousek EF, Gery I
    J. Immunol., 2010;185(11):6795-801.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  74. Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
    Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
    Am. J. Respir. Cell Mol. Biol., 2010;43(5):555-63.
    Species: Mouse
    Sample Type: Tissue Homogenates
  75. Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.
    Authors: Wright PL, Yu J, Di YP
    J. Exp. Med., 2010;207(12):2595-607.
    Species: Mouse
    Sample Type: BALF
  76. Mucosal vaccination using claudin-4-targeting.
    Authors: Kakutani H, Kondoh M, Fukasaka M, Suzuki H, Hamakubo T, Yagi K
    Biomaterials, 2010;31(20):5463-71.
    Species: Mouse
    Sample Type: Serum
  77. A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice.
    Authors: Shinagawa K, Ploplis VA, Castellino FJ
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(5):L763-70.
    Species: Mouse
    Sample Type: BALF
  78. Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice.
    Authors: Gram K, Yang S, Steiner M, Somani A, Hawgood S, Blazar BR, Panoskaltsis-Mortari A, Haddad IY
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(2):L167-75.
    Species: Mouse
    Sample Type: BALF
  79. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
    Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
    Nat. Med., 2009;15(10):1170-8.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  80. The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine.
    Authors: Liu J, Ngai N, Stone GW, Yue FY, Ostrowski MA
    Vaccine, 2009;27(37):5077-84.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  81. CCL2/MCP-1 controls parasite burden, cell infiltration, and mononuclear activation during acute Trypanosoma cruzi infection.
    Authors: Paiva CN, Figueiredo RT, Kroll-Palhares K, Silva AA, Silverio JC, Gibaldi D, Pyrrho Ados S, Benjamim CF, Lannes-Vieira J, Bozza MT
    J. Leukoc. Biol., 2009;86(5):1239-46.
    Species: Mouse
    Sample Type: Plasma
  82. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2009;21(1):81-93.
    Species: Mouse
    Sample Type: Tissue Homogenates
  83. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009;183(2):1291-300.
    Species: Mouse
    Sample Type: BALF
  84. Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7.
    Authors: Vultaggio A, Nencini F, Fitch PM, Fili L, Maggi L, Fanti P, deVries A, Beccastrini E, Palandri F, Manuelli C, Bani D, Giudizi MG, Guarna A, Annunziato F, Romagnani S, Maggi E, Howie SE, Parronchi P
    J. Immunol., 2009;182(2):880-9.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  85. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009;21(5):555-65.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  86. TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
    Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
    Vaccine, 2009;27(23):3045-52.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  87. Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.
    Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS
    J. Immunol., 2009;182(11):6907-14.
    Species: Mouse
    Sample Type: BALF
  88. Neutralization of Interleukin-18 Ameliorates Ischemia/Reperfusion-induced Myocardial Injury.
    Authors: Venkatachalam K, Prabhu SD, Reddy VS, Boylston WH, Valente AJ, Chandrasekar B
    J. Biol. Chem., 2009;284(12):7853-65.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  89. Vasoactive intestinal peptide attenuates concanavalin A-mediated liver injury.
    Authors: Luo Q, Wang Y, Feng D, Xu Y, Xu L
    Eur. J. Pharmacol., 2009;607(1):226-33.
    Species: Mouse
    Sample Type: Plasma
  90. Stearoyl-CoA desaturase 1 deficiency protects mice from immune-mediated liver injury.
    Authors: Feng D, Wang Y, Mei Y, Xu Y, Xu H, Lu Y, Luo Q, Zhou S, Kong X, Xu L
    Lab. Invest., 2009;89(2):222-30.
    Species: Mouse
    Sample Type: Plasma
  91. Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model.
    Authors: Kim DY, Park JW, Jeoung D, Ro JY
    Eur. J. Pharmacol., 2009;612(1):98-105.
    Species: Mouse
    Sample Type: BALF
  92. Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.
    Authors: Izumo T, Kondo M, Nagai A
    Eur. Respir. J., 2009;34(6):1444-51.
    Species: Mouse
    Sample Type: BALF
  93. Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.
    Authors: Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD
    Inflamm. Res., 2009;58(12):845-54.
    Species: Mouse
    Sample Type: BALF
  94. Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice.
    Authors: Sun Y, Qin Y, Gong FY, Wu XF, Hua ZC, Chen T, Xu Q
    Biochem. Pharmacol., 2009;77(11):1717-24.
    Species: Mouse
    Sample Type: Serum
  95. Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes.
    Authors: Herz J, Pardo J, Kashkar H, Schramm M, Kuzmenkina E, Bos E, Wiegmann K, Wallich R, Peters PJ, Herzig S, Schmelzer E, Kronke M, Simon MM, Utermohlen O
    Nat. Immunol., 2009;10(7):761-8.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  96. TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
    Authors: Thaxton JE, Romero R, Sharma S
    J. Immunol., 2009;183(2):1144-54.
    Species: Mouse
    Sample Type: Serum
  97. Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis.
    Authors: Ishida Y, Hayashi T, Goto T, Kimura A, Akimoto S, Mukaida N, Kondo T
    J. Immunol., 2008;181(6):4208-18.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  98. GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice.
    Authors: Hirose K, Wakashin H, Oki M, Kagami S, Suto A, Ikeda K, Watanabe N, Iwamoto I, Furuichi Y, Nakajima H
    Biochem. Biophys. Res. Commun., 2008;374(3):507-11.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  99. Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
    Authors: Templeton A, Nguyen G, Ash JD, Straub RH, Carr DJ
    J. Neuroimmunol., 2008;197(1):37-46.
    Species: Mouse
    Sample Type: Tissue Homogenates
  100. Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
    Authors: Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
    J. Exp. Med., 2008;205(9):2075-84.
    Species: Mouse
    Sample Type: Serum
  101. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase.
    Authors: Iwanami K, Matsumoto I, Tanaka-Watanabe Y, Inoue A, Mihara M, Ohsugi Y, Mamura M, Goto D, Ito S, Tsutsumi A, Kishimoto T, Sumida T
    Arthritis Rheum., 2008;58(3):754-63.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  102. Lycopene suppresses ovalbumin-induced airway inflammation in a murine model of asthma.
    Authors: Lee CM, Chang JH, Moon DO, Choi YH, Choi IW, Park YM, Kim GY
    Biochem. Biophys. Res. Commun., 2008;374(2):248-52.
    Species: Mouse
    Sample Type: BALF
  103. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
    Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
    Am. J. Pathol., 2008;172(5):1209-21.
    Species: Mouse
    Sample Type: Tissue Homogenates
  104. Staphylococcus aureus infection after splenectomy and splenic autotransplantation in BALB/c mice.
    Authors: Teixeira FM, Fernandes BF, Rezende AB, Machado RR, Alves CC, Perobelli SM, Nunes SI, Farias RE, Rodrigues MF, Ferreira AP, Oliveira SC, Teixeira HC
    Clin. Exp. Immunol., 2008;154(2):255-63.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  105. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008;590(1):400-8.
    Species: Mouse
    Sample Type: Tissue Homogenates
  106. Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide.
    Authors: Moon DO, Kim MO, Lee HJ, Choi YH, Park YM, Heo MS, Kim GY
    Biochem. Biophys. Res. Commun., 2008;375(2):275-9.
    Species: Mouse
    Sample Type: BALF
  107. Salmonella choleraesuis as an anticancer agent in a syngeneic model of orthotopic hepatocellular carcinoma.
    Authors: Lee CH, Wu CL, Shiau AL
    Int. J. Cancer, 2008;122(4):930-5.
    Species: Mouse
    Sample Type: Tissue Homogenates
  108. Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
    Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
    J. Immunol., 2008;181(2):1491-8.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  109. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.
    Authors: Kang MJ, Lee CG, Lee JY, Dela Cruz CS, Chen ZJ, Enelow R, Elias JA
    J. Clin. Invest., 2008;118(8):2771-84.
    Species: Mouse
    Sample Type: BALF
  110. The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response.
    Authors: Palma C, Iona E, Giannoni F, Pardini M, Brunori L, Fattorini L, Del Giudice G, Cassone A
    Vaccine, 2008;26(33):4237-43.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  111. Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein.
    Authors: Johnson TR, Rothenberg ME, Graham BS
    J. Leukoc. Biol., 2008;84(3):748-59.
    Species: Mouse
    Sample Type: Tissue Homogenates
  112. CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals.
    Authors: Liu J, Yu Q, Stone GW, Yue FY, Ngai N, Jones RB, Kornbluth RS, Ostrowski MA
    Vaccine, 2008;26(32):4062-72.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  113. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
    Authors: Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA
    J. Immunol., 2008;181(10):7157-65.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  114. Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes.
    Authors: Besin G, Gaudreau S, Menard M, Guindi C, Dupuis G, Amrani A
    Diabetes, 2008;57(8):2107-17.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  115. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
    Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
    Am. J. Pathol., 2007;170(4):1152-64.
    Species: Mouse
    Sample Type: Tissue Homogenates
  116. Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
    Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
    J. Allergy Clin. Immunol., 2007;119(1):123-31.
    Species: Mouse
    Sample Type: BALF
  117. Suppression of established experimental autoimmune uveitis by anti-LFA-1alpha Ab.
    Authors: Ke Y, Sun D, Zhang P, Jiang G, Kaplan HJ, Shao H
    Invest. Ophthalmol. Vis. Sci., 2007;48(6):2667-75.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  118. Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
    Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
    Immunology, 2007;122(2):268-78.
    Species: Mouse
    Sample Type: BALF
  119. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
    Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
    Transplantation, 2007;84(10):1279-87.
    Species: Mouse
    Sample Type: Serum
  120. Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma.
    Authors: Simeone-Penney MC, Severgnini M, Tu P, Homer RJ, Mariani TJ, Cohn L, Simon AR
    J. Immunol., 2007;178(10):6191-9.
    Species: Mouse
    Sample Type: BALF
  121. Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.
    Authors: Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F
    Immunol. Lett., 2007;116(1):86-94.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  122. Liposomal retinoic acids modulate asthma manifestations in mice.
    Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M
    J. Nutr., 2007;137(12):2730-6.
    Species: Mouse
    Sample Type: BALF
  123. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
    Authors: Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR
    J. Immunol., 2007;178(2):851-7.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  124. Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
    Authors: Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P
    Nat. Genet., 2007;39(3):329-37.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  125. Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
    Authors: Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A
    J. Immunol., 2007;179(6):3638-47.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  126. Prolonged inhaled allergen exposure can induce persistent tolerance.
    Authors: Van Hove CL, Maes T, Joos GF, Tournoy KG
    Am. J. Respir. Cell Mol. Biol., 2007;36(5):573-84.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  127. IL-17 receptor signaling influences virus-induced corneal inflammation.
    Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
    J. Leukoc. Biol., 2007;83(2):401-8.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  128. Potent induction of TNF-alpha during interaction of immune effectors with oral tumors as a potential mechanism for the loss of NK cell viability and function.
    Authors: Romero-Reyes M, Head C, Cacalano NA, Jewett A
    Apoptosis, 2007;12(11):2063-75.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  129. The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.
    Authors: Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic NL, Li LY
    J. Immunol., 2007;179(6):3742-51.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  130. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
    Authors: Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K
    J. Immunol., 2007;179(7):4415-23.
    Species: Mouse
    Sample Type: Serum
  131. Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene products.
    Authors: Yuasa K, Yoshimura M, Urasawa N, Ohshima S, Howell JM, Nakamura A, Hijikata T, Miyagoe-Suzuki Y, Takeda S
    Gene Ther., 2007;14(17):1249-60.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  132. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
    Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
    J. Immunol., 2007;178(10):6252-8.
    Species: Mouse
    Sample Type: Tissue Homogenates
  133. Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
    Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
    Blood, 2007;111(1):219-28.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  134. D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma.
    Authors: Lee JS, Lee CM, Jeong YI, Jung ID, Kim BH, Seong EY, Kim JI, Choi IW, Chung HY, Park YM
    FEBS Lett., 2007;581(1):57-64.
    Species: Mouse
    Sample Type: BALF
  135. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007;27(40):10695-702.
    Species: Mouse
    Sample Type: Serum
  136. Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production.
    Authors: Gill N, Deacon PM, Lichty B, Mossman KL, Ashkar AA
    J. Virol., 2006;80(20):9943-50.
    Species: Mouse
    Sample Type: Vaginal Lavage
  137. Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model.
    Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T
    Biosci. Biotechnol. Biochem., 2006;70(8):2013-7.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  138. A multivalent combination of experimental antituberculosis DNA vaccines based on Ag85B and regions of difference antigens.
    Authors: Grover A, Ahmed MF, Singh B, Verma I, Sharma P, Khuller GK
    Microbes Infect., 2006;8(9):2390-9.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  139. Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis.
    Authors: Furuta T, Yoshikawa Y
    Int. Immunol., 2006;18(12):1655-62.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  140. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006;18(11):1531-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
  141. Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
    Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
    J. Virol., 2006;80(20):9977-87.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  142. Perforin-deficient CD8+ T cells mediate fatal lymphocytic choriomeningitis despite impaired cytokine production.
    Authors: Storm P, Bartholdy C, Sorensen MR, Christensen JP, Thomsen AR
    J. Virol., 2006;80(3):1222-30.
    Species: Mouse
    Sample Type: Serum
  143. Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.
    Authors: Weighardt H, Kaiser-Moore S, Schlautkotter S, Rossmann-Bloeck T, Schleicher U, Bogdan C, Holzmann B
    J. Immunol., 2006;177(8):5623-30.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  144. CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli.
    Authors: Tsunemi Y, Saeki H, Nakamura K, Nagakubo D, Nakayama T, Yoshie O, Kagami S, Shimazu K, Kadono T, Sugaya M, Komine M, Matsushima K, Tamaki K
    Eur. J. Immunol., 2006;36(8):2116-27.
    Species: Mouse
    Sample Type: Tissue Homogenates
  145. Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
    Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
    Am. J. Pathol., 2006;168(4):1189-99.
    Species: Mouse
    Sample Type: Blister Fluid
  146. The differential effects of low dose and high dose concanavalin A on cytokine profile and their importance in liver injury.
    Authors: Xu X, Wei H, Dong Z, Chen Y, Tian Z
    Inflamm. Res., 2006;55(4):144-52.
    Species: Mouse
    Sample Type: Serum
  147. Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
    Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
    J. Immunol., 2006;176(4):2568-80.
    Species: Mouse
    Sample Type: Serum
  148. Blockade of transforming growth factor-{beta} signaling in tumor-reactive CD8(+) T cells activates the antitumor immune response cycle.
    Authors: Zhang Q, Yang XJ, Kundu SD, Pins M, Javonovic B, Meyer R, Kim SJ, Greenberg NM, Kuzel T, Meagher R, Guo Y, Lee C
    Mol. Cancer Ther., 2006;5(7):1733-43.
    Species: Mouse
    Sample Type: Serum
  149. Prevention of murine experimental autoimmune encephalomyelitis by in vivo expression of a novel recombinant immunotoxin DT390-RANTES.
    Authors: Jia Y, Li H, Chen W, Li M, Lv M, Feng P, Hu H, Zhang L
    Gene Ther., 2006;13(18):1351-9.
    Species: Mouse
    Sample Type: Serum
  150. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
    Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
    Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  151. Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer.
    Authors: Hahn T, Alvarez I, Kobie JJ, Ramanathapuram L, Dial S, Fulton A, Besselsen D, Walker E, Akporiaye ET
    Int. J. Cancer, 2006;118(9):2220-31.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  152. Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease.
    Authors: Bhagwat SP, Gigliotti F, Xu H, Wright TW
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1256-66.
    Species: Mouse
    Sample Type: BALF
  153. Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice.
    Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M
    Vaccine, 2005;24(9):1470-7.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  154. Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.
    Authors: Duan W, Chan JH, McKay K, Crosby JR, Choo HH, Leung BP, Karras JG, Wong WS
    Am. J. Respir. Crit. Care Med., 2005;171(6):571-8.
    Species: Mouse
    Sample Type: BALF
  155. DNA vaccine encoding Der p 2 allergen generates immunologic protection in recombinant Der p 2 allergen-induced allergic airway inflammation mice model.
    Authors: Li GP, Liu ZG, Ran PX, Zhong NS
    Chin. Med. J., 2005;118(7):534-40.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  156. Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.
    Authors: Gueders MM, Balbin M, Rocks N, Foidart JM, Gosset P, Louis R, Shapiro S, Lopez-Otin C, Noel A, Cataldo DD
    J. Immunol., 2005;175(4):2589-97.
    Species: Mouse
    Sample Type: BALF
  157. Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice.
    Authors: Shibamori M, Ogino K, Kambayashi Y, Ishiyama H
    Life Sci., 2005;78(9):987-94.
    Species: Mouse
    Sample Type: BALF
  158. Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
    Authors: Weijer S, Florquin S, van der Poll T
    Shock, 2005;23(1):54-8.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  159. Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
    Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
    Anticancer Res., 2005;25(1):299-303.
    Species: Mouse
    Sample Type: Tissue Secretion
  160. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004;21(2):241-54.
    Species: Mouse
    Sample Type: Plasma
  161. Control of Leishmania major in the absence of Tyk2 kinase.
    Authors: Schleicher U, Mattner J, Blos M, Schindler H, Rollinghoff M, Karaghiosoff M, Muller M, Werner-Felmayer G, Bogdan C
    Eur. J. Immunol., 2004;34(2):519-29.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  162. Cytokine expression in experimental chronic otitis media with effusion in mice.
    Authors: Maeda K, Hirano T, Ichimiya I, Kurono Y, Suzuki M, Mogi G
    Laryngoscope, 2004;114(11):1967-72.
    Species: Mouse
    Sample Type: Tissue Secretion
  163. Single intranasal mucosal Mycobacterium bovis BCG vaccination confers improved protection compared to subcutaneous vaccination against pulmonary tuberculosis.
    Authors: Chen L, Wang J, Zganiacz A, Xing Z
    Infect. Immun., 2004;72(1):238-46.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  164. In vivo effects of interleukin-17 on haematopoietic cells and cytokine release in normal mice.
    Authors: Jovcic G, Bugarski D, Petakov M, Krstic A, Vlaski M, Stojanovic N, Milenkovic P
    Cell Prolif., 2004;37(6):401-12.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  165. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004;172(12):7408-16.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  166. Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV.
    Authors: Johnson TR, Varga SM, Braciale TJ, Graham BS
    J. Virol., 2004;78(16):8753-60.
    Species: Mouse
    Sample Type: Tissue Homogenates
  167. Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
    Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
    Circulation, 2004;110(11):II194-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
  168. Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
    Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
    Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411.
    Species: Mouse
    Sample Type: Serum
  169. MHC class II-associated invariant chain isoforms regulate pulmonary immune responses.
    Authors: Ye Q, Finn PW, Sweeney R, Bikoff EK, Riese RJ
    J. Immunol., 2003;170(3):1473-80.
    Species: Human
    Sample Type: BALF
  170. A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection.
    Authors: Harandi AM, Eriksson K, Holmgren J
    J. Virol., 2003;77(2):953-62.
    Species: Mouse
    Sample Type: Serum
  171. Dual roles of IL-4 in lung injury and fibrosis.
    Authors: Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH
    J. Immunol., 2003;170(4):2083-92.
    Species: Mouse
    Sample Type: Serum
  172. Anti-tumor mechanism of Z-100, an immunomodulatory Arabinomannan extracted from Mycobacterium tuberculosis strain Aoyama B, on pulmonary metastases of B16F10 melanoma: restoration of helper T cell responses via suppression of glucocorticoid-genesis.
    Authors: Oka H, Emori Y, Sasaki H, Shiraishi Y, Yoshinaga K, Kurimoto T
    Microbiol. Immunol., 2002;46(5):343-51.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  173. A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.
    Authors: Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D
    J. Immunol., 2002;169(5):2653-61.
    Species: Mouse
    Sample Type: Tissue Homogenates
  174. Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.
    Authors: Hixon JA, Anver MR, Blazar BR, Panoskaltsis-Mortari A, Wiltrout RH, Murphy WJ
    Biol. Blood Marrow Transplant., 2002;8(6):316-25.
    Species: Mouse
    Sample Type: Serum
  175. Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice.
    Authors: Fulton SA, Reba SM, Martin TD, Boom WH
    Infect. Immun., 2002;70(9):5322-7.
    Species: Mouse
    Sample Type: BALF
  176. Leptin accelerates autoimmune diabetes in female NOD mice.
    Authors: Matarese G, Sanna V, Lechler RI, Sarvetnick N, Fontana S, Zappacosta S, La Cava A
    Diabetes, 2002;51(5):1356-61.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  177. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.
    Authors: O&amp;amp;apos;shea JJ
    Proc. Natl. Acad. Sci. U.S.A., 2002;99(19):12281-6.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  178. Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
    Authors: Miller G, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
    J. Immunol., 2002;169(6):2875-85.
    Species: Mouse
    Sample Type: Serum
  179. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.
    Authors: Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y
    J. Immunol., 2002;168(9):4764-71.
  180. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001;31(7):2104-15.
    Species: Mouse
    Sample Type: Cell Culture Supernates
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  Excellent
  Anonymous 03/23/2018
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Sample Tested Serum

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Other Experimental Details We use this kit routinely in our lab with very consistent reliable results. Would certainly recommend!
 Mouse IFN-gamma Quantikine ELISA Kit MIF00 Array MIF00
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  Anonymous 03/23/2018
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 Mouse IFN-gamma Quantikine ELISA Kit MIF00
: Mouse IFN-gamma Quantikine ELISA Kit [MIF00].

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Sample Tested mouse serum
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  Anonymous 12/01/2017
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Sample Tested Cell culture supernatant
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  Anonymous 05/02/2017
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Sample Tested RAW 264.7 mouse monocyte/macrophage cell line
 Mouse IFN-gamma Quantikine ELISA Kit MIF00 Array MIF00
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  Anonymous 04/27/2017
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 Mouse IFN-gamma Quantikine ELISA Kit MIF00
: Mouse IFN-gamma Quantikine ELISA Kit [MIF00].

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Sample Tested Mouse primary CD8 cells

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Other Experimental Details Additional washes were added. Control or drug-treated CD8 cells were treated with allogeneic APC for 24 or 48 hours. Supernatants were subjected to IFN-g ELISA per manufacture's recommendation.

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