Mouse IL-17 DuoSet ELISA

Catalog # Availability Size / Price Qty
DY421
DY421-05
Ancillary Products Available
Mouse IL-17 / IL-17A ELISA Standard Curve
1 Image
Product Details
Procedure
Citations (148)
FAQs
Supplemental Products
Reviews (11)

Mouse IL-17 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-17. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Data Example

Mouse IL-17 / IL-17A ELISA Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-17/IL-17A

Mouse Interleukin 17 (IL-17; also known as IL-17A and CTLA-8) is a 21 kDa, variably glycosylated polypeptide that belongs to the IL-17 family of cytokines containing a cysteine-knot fold (1-3). Its sequence was originally isolated from an activated hybridoma created from the fusion of a mouse cytotoxic and rat T cell lymphoma cell line (2-5). It is synthesized as a 158 amino acid (aa) precursor that contains a 25 aa signal sequence and a 15 kDa, 133 aa mature segment (5). In both mouse and human, there is one conserved N-linked glycosylation site that likely contributes 5 kDa to its native molecular weight. IL-17A forms both a 35-38 kDa homodimer, and a 45-48 kDa heterodimer with IL-17F (6, 7). Mature mouse IL-17A is 61% and 89% aa identical to human and rat IL-17A, respectively (4, 5, 8). While rodent and human mature sequences show modest aa sequence identity, human IL-17 is active on both mouse and rat cells (5, 9). Cells known to produce IL-17 are the CD4+ Th17 T cells, Paneth cells, GR1+CD11b+ myeloid suppressor cells, CD27-gamma δ T cells, CD1+NK1.1- iNKT cells and CD3- CD4+ LTi-like cells (3, 5, 6, 10-12). 

A high affinity receptor for mouse IL-17 has been reported, and appears to be a heteromultimer of IL-17RA and IL-17RC, likely in a 2:1 ratio (1). IL-17RA is a 130 kDa, type I transmembrane glycoprotein that bears no resemblance to members of the cytokine, TNF or immunoglobulin receptor superfamily (2, 10, 13). IL-17RC is also a type I transmembrane protein, approximately 90-95 kDa in size, that shares less than 30% aa identity with IL-17RA (14, 15). Both receptors are needed for IL-17A and IL-17A/F activity. The two receptors appear to form a functional association following ligand binding to IL-17RA (1, 16). 
IL-17 is best known for its participation in the recruitment and survival of neutrophils (3, 10, 17, 18). Its induction was initially described to be the result of antigen stimulation of dentritic cells, resulting in IL-23 secretion. In a TCR-independent event, IL-23 induces T cell production of IL-17 (3). Once secreted, IL-17 in the bone marrow would seem to induce stromal/fibroblast expression of both G-CSF and SCF (membrane form), an effect that increases neutrophil differentiation and activation. IL-17 may complement this by directly blocking neutrophil apoptosis, promoting greater circulating neutrophil numbers (17). In the tissues, IL-17 seems to promote neutrophil extravasation, principally through its effects on macrophages and endothelial cells (EC). On macrophages, IL-17 induces TNF-alpha, IL-1 beta and IL-6 production (19). TNF-alpha and IL-1 beta then act on local ECs to induce G-CSF secretion, an effect that is potentiated by IL-17 (20). IL-17 further contributes to neutrophil influx by inducing EC CXC chemokine release and NO production, which may increase vascular permeability (3, 9). IL-17 effects are not limited to neutrophils. In synovial joints, IL-17 upregulates RANKL expression on osteoblasts. This provides a stimulus for osteoclast formation and subsequent bone resorption (18).

Long Name:
Interleukin 17
Entrez Gene IDs:
3605 (Human); 16171 (Mouse); 301289 (Rat); 449530 (Porcine); 481837 (Canine); 102119976 (Cynomolgus Monkey)
Alternate Names:
CTLA8; CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Mouse IL-17 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

148 Citations: Showing 1 - 10
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  1. Standardized herbal extract PM014 alleviates fine dust-induced lung inflammation in mice
    Authors: YS Lee, D Min, SY Park, J Lee, H Bae
    BMC Complement Med Ther, 2020;20(1):270.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Herbal Combinational Medication of Glycyrrhiza glabra, Agastache rugosa Containing Glycyrrhizic Acid, Tilianin Inhibits Neutrophilic Lung Inflammation by Affecting CXCL2, Interleukin-17/STAT3 Signal Pathways in a Murine Model of COPD
    Authors: SH Kim, JH Hong, WK Yang, JH Geum, HR Kim, SY Choi, YM Kang, HJ An, YC Lee
    Nutrients, 2020;12(4):.
    Species: Mouse
    Sample Types: BALF
  3. Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses
    Authors: J Hrdý, J Alard, A Couturier-, O Boulard, D Boutillier, M Delacre, C Lapadatesc, A Cesaro, P Blanc, B Pot, B Ryffel, M Chamaillar, C Grangette
    Sci Rep, 2020;10(1):5345.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  4. Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation
    Authors: LRC de Oliveir, LAN Mimura, TFC Fraga-Silv, LLW Ishikawa, AAH Fernandes, SFG Zorzella-P, A Sartori
    Front Pharmacol, 2020;11(0):161.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  5. Lactobacillus reuteri attenuated allergic inflammation induced by HDM in the mouse and modulated gut microbes
    Authors: L Li, Z Fang, X Liu, W Hu, W Lu, YK Lee, J Zhao, H Zhang, W Chen
    PLoS ONE, 2020;15(4):e0231865.
    Species: Mouse
    Sample Types: BALF
  6. Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis
    Authors: KI Lee, JS Bae, EH Kim, JH Kim, L Lyu, YJ Chung, JH Mo
    Clin Exp Otorhinolaryngol, 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation
    Authors: JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation
    Authors: F Silva-de-F, IM Villas-Boa, SMT Serrano, B Cogliati, SAA Chudzinski, PH Lopes, ES Kitano, CK Okamoto, DV Tambourgi
    PLoS Negl Trop Dis, 2019;13(1):e0007017.
    Species: Mouse
    Sample Types: Plasma
  9. Inhibition of IL-17 ameliorates systemic lupus erythematosus in Roquinsan/san mice through regulating the balance of TFH cells, GC B cells, Treg and Breg
    Authors: SY Lee, SH Lee, HB Seo, JG Ryu, K Jung, JW Choi, J Jhun, JS Park, JY Kwon, SK Kwok, J Youn, SH Park, ML Cho
    Sci Rep, 2019;9(1):5227.
    Species: Mouse
    Sample Types: Serum
  10. Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines
    Authors: CJH Davitt, S Longet, A Albutti, V Aversa, S Nordqvist, B Hackett, CP McEntee, M Rosa, IS Coulter, M Lebens, J Tobias, J Holmgren, EC Lavelle
    Mucosal Immunol, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  11. DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation
    Authors: M Costanza, PL Poliani, P Portararo, B Cappetti, S Musio, F Pagani, L Steinman, MP Colombo, R Pedotti, S Sangaletti
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  12. In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
    Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
    EBioMedicine, 2019;0(0):.
    Species: Mouse
    Sample Types: Plasma
  13. The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice
    Authors: BVS Valiate, RU Alvarez, L Karra, CM Queiroz-Jú, FA Amaral, F Levi-Schaf, MM Teixeira
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  14. Frontline Science: Abnormalities in the gut mucosa of non-obese diabetic mice precede the onset of type 1 diabetes
    Authors: MCG Miranda, RP Oliveira, L Torres, SLF Aguiar, N Pinheiro-R, L Lemos, MA Guimarães, D Reis, T Silveira, Ê Ferreira, TG Moreira, DC Cara, TU Maioli, BL Kelsall, D Carlos, AMC Faria
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  15. Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality
    Authors: U Kulkarni, RL Zemans, CA Smith, SC Wood, JC Deng, DR Goldstein
    Mucosal Immunol, 2019;12(2):545-554.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  16. Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection
    Authors: W Zhou, Y Yang, C Mei, P Dong, S Mu, H Wu, Y Zhou, Y Zheng, F Guo, JQ Yang
    Cells, 2019;8(10):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  17. Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms
    Authors: N Kaushansky, E Bakos, S Becker-Her, I Shachar, A Ben-Nun
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  18. Generation of protective pneumococcal-specific nasal resident memory CD4+ T cells via parenteral immunization
    Authors: JM O'Hara, NS Redhu, E Cheung, NG Robertson, I Patik, SE Sayed, CM Thompson, M Herd, KB Lucas, E Conaway, CC Morton, DL Farber, R Malley, BH Horwitz
    Mucosal Immunol, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model
    Authors: N Taghipour, N Mosaffa, HA Aghdaei, M Rostami-Ne, JV Weinstock, S Shahnavaz, MR Zali
    Sci Rep, 2019;9(1):19127.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  20. DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells
    Authors: A Suhail, ZA Rizvi, P Mujagond, SA Ali, P Gaur, M Singh, V Ahuja, A Awasthi, CV Srikanth
    Cell Rep, 2019;29(11):3522-3538.e7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  21. Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni
    Authors: MC de Rezende, JMP Moreira, LLM Fernandes, VF Rodrigues, D Negrão-Cor
    Cytokine, 2019;127(0):154931.
    Species: Mouse
    Sample Types: Tissue Homogenates
  22. Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse ?? T Cell Effector Differentiation
    Authors: P Zarin, TSH In, ELY Chen, J Singh, GW Wong, M Mohtashami, DL Wiest, MK Anderson, JC Zúñiga-Pfl
    Immunol. Cell Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  23. Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
    Authors: CC Campa, RL Silva, JP Margaria, T Pirali, MS Mattos, LR Kraemer, DC Reis, G Grosa, F Copperi, EM Dalmarco, RCP Lima-Júnio, S Aprile, V Sala, F Dal Bello, DS Prado, JC Alves-Filh, C Medana, GD Cassali, GC Tron, MM Teixeira, E Ciraolo, RC Russo, E Hirsch
    Nat Commun, 2018;9(1):5232.
    Species: Mouse
    Sample Types:
  24. Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota
    Authors: C Tang, S Kakuta, K Shimizu, M Kadoki, T Kamiya, T Shimazu, S Kubo, S Saijo, H Ishigame, S Nakae, Y Iwakura
    Nat. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  25. Fraxinellone Attenuates Rheumatoid Inflammation in Mice
    Authors: SM Jung, J Lee, SY Baek, J Lee, SG Jang, SM Hong, JS Park, ML Cho, SH Park, SK Kwok
    Int J Mol Sci, 2018;19(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  26. Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice
    Authors: IS de Genaro, FM de Almeida, DC Hizume-Kun, HT Moriya, RA Silva, JCG Cruz, RB Lopes, RF Righetti, R de Paula V, M Saiki, MA Martins, IFLC Tibério, FM Arantes-Co, BM Saraiva-Ro
    Sci Rep, 2018;8(1):12636.
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis
    Authors: M Imbrechts, A Avau, J Vandenhaut, B Malengier-, K Put, T Mitera, N Berghmans, O Burton, S Junius, A Liston, L de Somer, C Wouters, P Matthys
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy
    Authors: PP Ho, LJ Lahey, F Mourkioti, PE Kraft, A Filareto, M Brandt, KEG Magnusson, EE Finn, JS Chamberlai, WH Robinson, HM Blau, L Steinman
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  29. Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection
    Authors: T Imai, T Matsumura, S Mayer-Lamb, CA Wells, E Ishikawa, SK Butcher, TC Barnett, MJ Walker, A Imamura, H Ishida, T Ikebe, T Miyamoto, M Ato, S Ohga, B Lepenies, NM van Sorge, S Yamasaki
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  30. Repeated Allergen Exposure in A/J Mice Causes Steroid-Insensitive Asthma via a Defect in Glucocorticoid Receptor Bioavailability
    Authors: MF Serra, AC Cotias, CRR Pão, JB Daleprane, PB Jurgilas, GC Couto, EA Anjos-Valo, RSB Cordeiro, VF Carvalho, PMR Silva, MA Martins
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  31. PrtA immunization fails to protect against pulmonary and invasive infection by Streptococcus pneumoniae
    Authors: CF Hsu, CH Hsiao, SF Tseng, JR Chen, YJ Liao, SJ Chen, CS Lin, HK Sytwu, YP Chuang
    Respir. Res., 2018;19(1):187.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  32. IL-23R Signaling Plays No Role in Myocardial Infarction
    Authors: E Engelowski, NF Modares, S Gorressen, P Bouvain, D Semmler, C Alter, Z Ding, U Flögel, J Schrader, H Xu, PA Lang, J Fischer, DM Floss, J Scheller
    Sci Rep, 2018;8(1):17078.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  33. ATX-MS-1467 Induces Long-Term Tolerance to Myelin Basic Protein in (DR2?�?Ob1)F1 Mice by Induction of IL-10-Secreting iTregs
    Authors: ALS De Souza, S Rudin, R Chang, K Mitchell, T Crandall, S Huang, JK Choi, SL Okitsu, DL Graham, B Tomkinson, T Dellovade
    Neurol Ther, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  34. A novel multi-peptide subunit vaccine admixed with AddaVax adjuvant produces significant immunogenicity and protection against Proteus mirabilis urinary tract infection in mice model
    Authors: E Choubini, M Habibi, A Khorshidi, A Ghasemi, MR Asadi Kara, S Bouzari
    Mol. Immunol., 2018;96(0):88-97.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Standard
  35. STAT-3-independent production of IL-17 by mouse innate-like ?? T cells controls ocular infection
    Authors: AJ St Leger, AM Hansen, H Karauzum, R Horai, CR Yu, A Laurence, KD Mayer-Barb, P Silver, R Villasmil, C Egwuagu, SK Datta, RR Caspi
    J. Exp. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  36. Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection
    Authors: N Hernández-, DL Wiesner, JS Fites, AJ McDermott, T Warner, M Wüthrich, BS Klein
    Cell Host Microbe, 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  37. Lactobacillus fermentum HP3-Mediated Fermented Hericium erinaceus Juice as a Health Promoting Food Supplement to Manage Diabetes Mellitus
    Authors: C Chaiyasut, S Woraharn, BS Sivamaruth, N Lailerd, P Kesika, S Peerajan
    J Evid Based Integr Med, 2018;23(0):2515690X18765.
    Species: Rat
    Sample Types: Serum
  38. Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota
    Authors: HT Groves, L Cuthbertso, P James, MF Moffatt, MJ Cox, JS Tregoning
    Front Immunol, 2018;9(0):182.
    Species: Mouse
    Sample Types: Airway Lavage Fluid
  39. Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon
    Authors: S Bettini, E Boutet-Rob, C Cartier, C Com‚ra, E Gaultier, J Dupuy, N Naud, S Tach‚, P Grysan, S Reguer, N Thieriet, M R‚fr‚giers, D ThiaudiŠre, JP Cravedi, M CarriŠre, JN Audinot, FH Pierre, L Guzylack-P, E Houdeau
    Sci Rep, 2017;7(0):40373.
    Species: Rat
    Sample Types: Tissue Homogenates
  40. Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion
    Authors: JS Bowers, MH Nelson, K Majchrzak, SR Bailey, B Rohrer, AD Kaiser, C Atkinson, L Gattinoni, CM Paulos
    JCI Insight, 2017;2(5):e90772.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
    Authors: A Imai, K Satoi, E Fujimoto, K Sato
    Heliyon, 2017;3(6):e00327.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  42. Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice
    Authors: J Tode, E Richert, S Koinzer, A Klettner, U Pickhinke, C Garbers, S Rose-John, B Nölle, J Roider
    Cytokine, 2017;96(0):8-15.
    Species: Mouse
    Sample Types: Tissue Homogenates
  43. Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection
    Authors: LA Sacramento, JL da Costa, MH de Lima, PA Sampaio, RP Almeida, FQ Cunha, JS Silva, V Carregaro
    Front Microbiol, 2017;8(0):262.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  44. IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice
    Authors: TB Oriss, M Raundhal, C Morse, RE Huff, S Das, R Hannum, MC Gauthier, KL Scholl, K Chakrabort, SM Nouraie, SE Wenzel, P Ray, A Ray
    JCI Insight, 2017;2(10):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  45. Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function
    Authors: T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  46. Influence of hydrocarbon oil structure on adjuvanticity and autoimmunity
    Authors: ACY Yau, E Lönnblom, J Zhong, R Holmdahl
    Sci Rep, 2017;7(1):14998.
    Species: Rat
    Sample Types: Cell Culture Supernates
  47. Schistosoma japonicum infection downregulates house dust mite-induced allergic airway inflammation in mice
    Authors: S Qiu, X Fan, Y Yang, P Dong, W Zhou, Y Xu, Y Zhou, F Guo, Y Zheng, JQ Yang
    PLoS ONE, 2017;12(6):e0179565.
    Species: Mouse
    Sample Types: BALF
  48. Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis
    Authors: L Serre, M Girard, A Ramadan, P Menut, N Rouquié, LE Lucca, K Mahiddine, B Leobon, LT Mars, S Guerder
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  49. Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation
    Authors: A Hammer, A Schliep, S Jörg, A Haghikia, R Gold, M Kleinewiet, DN Müller, RA Linker
    J Neuroinflammation, 2017;14(1):184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  50. Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related with IL-12 signaling
    Authors: Dorothee Schwinge
    J. Hepatol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Secretion
  52. Interleukin-27 Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response
    Authors: Gustavo F S Quirino
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  53. The circadian clock regulates inflammatory arthritis
    FASEB J, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  54. Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
    Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
    PLoS ONE, 2016;11(4):e0153829.
    Species: Mouse
    Sample Types: Tissue Homogenates
  55. Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration
    Invest. Ophthalmol. Vis. Sci., 2016;57(3):1441-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  56. Allergen-Induced IL-6 Regulates IL-9/IL-17A Balance in CD4+ T Cells in Allergic Airway Inflammation
    J Immunol, 2016;197(7):2653-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. T-bet overexpression regulates AHR-mediated Th-17 differentiation through an IFN?-independent pathway
    Authors: Masahiro Yokosawa
    Clin. Exp. Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  58. Impact of Histone H1 on the Progression of Allergic Rhinitis and Its Suppression by Neutralizing Antibody in Mice
    Authors: T Nakano, R Kamei, T Fujimura, Y Takaoka, A Hori, CY Lai, KC Chiang, Y Shimada, N Ohmori, T Goto, K Ono, CL Chen, S Goto, S Kawamoto
    PLoS ONE, 2016;11(4):e0153630.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  59. Interleukin 7 immunotherapy improves host immunity and survival in a two-hit model of Pseudomonas aeruginosa pneumonia
    J Leukoc Biol, 2016;0(0):.
    Species: Mouse
    Sample Types: Plasma
  60. Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
    EBioMedicine, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  61. IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression
    Authors: JL Reyes, MR Fernando, F Lopes, G Leung, NL Mancini, CE Matisz, A Wang, DM McKay
    PLoS Pathog, 2016;12(4):e1005481.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms.
    Authors: Tsao C, Tsao P, Chen Y, Chuang Y
    PLoS ONE, 2016;11(1):e0147710.
    Species: Mouse
    Sample Types: BALF
  63. Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis
    Authors: Pan Su
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  64. DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma
    JCI Insight, 2016;1(18):e88811.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. Myelin Oligodendrocyte Glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self antigen in mice
    Authors: Liliana E Lucca
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  66. Metabolic and adaptive immune responses induced in mice infected with tissue-dwelling nematode Trichinella zimbabwensis
    Authors: S Mukaratirw
    Open Vet J, 2016;6(3):178-184.
    Species: Mouse
    Sample Types: Serum
  67. AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-?B and STAT3 Pathways
    Sci Rep, 2016;6(0):31912.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  68. Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation.
    Authors: McCarthy M, Procario M, Wilke C, Moore B, Weinberg J
    PLoS ONE, 2015;10(9):e0139235.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  69. Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.
    Authors: Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse A, Herkel J, Schramm C
    J Immunol, 2015;194(6):2522-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  70. Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
    Authors: Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
    PLoS Pathog, 2015;11(11):e1005226.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  71. Unexpected Role for Adaptive alphabetaTh17 Cells in Acute Respiratory Distress Syndrome.
    Authors: Li J, Melton A, Su G, Hamm D, LaFemina M, Howard J, Fang X, Bhat S, Huynh K, O'Kane C, Ingram R, Muir R, McAuley D, Matthay M, Sheppard D
    J Immunol, 2015;195(1):87-95.
    Species: Mouse
    Sample Types: BALF
  72. Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
    Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
    Eur J Immunol, 2015;45(9):2553-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  73. Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease.
    Authors: Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen B, Nielsen C, Milo R, Zeilig G, Lassmann H, Altmann D, Ben-Nun A
    J Biol Chem, 2015;290(24):15260-78.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  74. Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis.
    Authors: Ho P, Steinman L
    Proc Natl Acad Sci U S A, 2015;113(6):1600-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets.
    Authors: Knudson C, Hartwig S, Meyerholz D, Varga S
    PLoS Pathog, 2015;11(3):e1004757.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  76. De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes.
    Authors: Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P
    J Immunol, 2015;194(12):5812-24.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  77. Genome-wide transcriptional analyses of islet-specific CD4+ T cells identify Idd9 genes controlling diabetogenic T cell function.
    Authors: Berry G, Frielle C, Luu T, Salzberg A, Rainbow D, Wicker L, Waldner H
    J Immunol, 2015;194(6):2654-63.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  78. Cooperation between IL-7 Receptor and Integrin alpha2beta1 (CD49b) Drives Th17-Mediated Bone Loss.
    Authors: El Azreq M, Arseneault C, Boisvert M, Page N, Allaeys I, Poubelle P, Tessier P, Aoudjit F
    J Immunol, 2015;195(9):4198-209.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  79. DCIR maintains bone homeostasis by regulating IFN-gamma production in T cells.
    Authors: Maruhashi T, Kaifu T, Yabe R, Seno A, Chung S, Fujikado N, Iwakura Y
    J Immunol, 2015;194(12):5681-91.
    Species: Mouse
    Sample Types: Tissue Homogenates
  80. A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
    Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
    Mucosal Immunol, 2015;8(5):982-92.
    Species: Mouse
    Sample Types: Tissue Homogenates
  81. Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.
    Authors: Monin L, Griffiths K, Slight S, Lin Y, Rangel-Moreno J, Khader S
    Mucosal Immunol, 2015;8(5):1099-109.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  82. Positional identification of RT1-B (HLA-DQ) as susceptibility locus for autoimmune arthritis.
    Authors: Haag S, Tuncel J, Thordardottir S, Mason D, Yau A, Dobritzsch D, Backlund J, Peters E, Holmdahl R
    J Immunol, 2015;194(6):2539-50.
    Species: Rat
    Sample Types: Cell Culture Supernates
  83. Cholera toxin adjuvant promotes a balanced Th1/Th2/Th17 response independently of IL-12 and IL-17 by acting on Gsalpha in CD11b(+) DCs.
    Authors: Mattsson J, Schon K, Ekman L, Fahlen-Yrlid L, Yrlid U, Lycke N
    Mucosal Immunol, 2015;8(4):815-27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  84. Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cells.
    Authors: Lee H, Ko J, Jeong H, Ko A, Kim M, Wee W, Yoon S, Oh J
    J Immunol, 2015;194(8):3634-45.
    Species: Mouse
    Sample Types: Tissue Homogenates
  85. Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection.
    Authors: Dong X, Liu Y, Chang X, Lei L, Zhong G
    Infect Immun, 2014;82(5):1833-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014;4(0):4146.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  87. Delineating the role of histamine-1- and -4-receptors in a mouse model of Th2-dependent antigen-specific skin inflammation.
    Authors: Mahapatra S, Albrecht M, Behrens B, Jirmo A, Behrens G, Hartwig C, Neumann D, Raap U, Bahre H, Herrick C, Dittrich A
    PLoS ONE, 2014;9(2):e87296.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  88. A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.
    Authors: Vacchio M, Wang L, Bouladoux N, Carpenter A, Xiong Y, Williams L, Wohlfert E, Song K, Belkaid Y, Love P, Bosselut R
    Nat Immunol, 2014;15(10):947-56.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  89. Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-gamma pathway.
    Authors: Badr M, Qinna N, Qadan F, Matalka K
    Onco Targets Ther, 2014;7(0):193-201.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  90. The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development.
    Authors: Hayes M, Ovcinnikovs V, Smith A, Kimber I, Dearman R
    PLoS ONE, 2014;9(9):e106955.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  91. IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
    Authors: Hams, Emily, Armstrong, Michelle, Barlow, Jillian, Saunders, Sean P, Schwartz, Christia, Cooke, Gordon, Fahy, Ruairi J, Crotty, Thomas B, Hirani, Nikhil, Flynn, Robin J, Voehringer, David, McKenzie, Andrew N, Donnelly, Seamas C, Fallon, Padraic
    Proc Natl Acad Sci U S A, 2014;111(1):367-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  92. IFN-gamma-producing and IL-17-producing gammadelta T cells differentiate at distinct developmental stages in murine fetal thymus.
    Authors: Shibata K, Yamada H, Nakamura M, Hatano S, Katsuragi Y, Kominami R, Yoshikai Y
    J Immunol, 2014;192(5):2210-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  93. The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma.
    Authors: Ubel C, Sopel N, Graser A, Hildner K, Reinhardt C, Zimmermann T, Rieker R, Maier A, Neurath M, Murphy K, Finotto S
    J Allergy Clin Immunol, 2014;133(1):198-206.e1-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  94. Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice.
    Authors: Lv J, Wang D, Hua Y, Pei S, Wang J, Hu W, Wang X, Jia N, Jiang Q
    BMC Infect Dis, 2014;14(0):197.
    Species: Mouse
    Sample Types: Tissue Homogenates
  95. MyD88 signaling regulates both host defense and immunopathogenesis during pneumocystis infection.
    Authors: Bello-Irizarry S, Wang J, Johnston C, Gigliotti F, Wright T
    J Immunol, 2014;192(1):282-92.
    Species: Mouse
    Sample Types: BALF
  96. IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.
    Authors: Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T
    Nat Commun, 2014;5(0):3770.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  97. Staphylococcus aureus infection of mice expands a population of memory gammadelta T cells that are protective against subsequent infection.
    Authors: Murphy A, O'Keeffe K, Lalor S, Maher B, Mills K, McLoughlin R
    J Immunol, 2014;192(8):3697-708.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  98. Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.
    Authors: Post, Sijranke, Heijink, Irene H, Petersen, Arjen H, de Bruin, Harold G, van Oosterhout, Antoon J, Nawijn, Martijn
    PLoS ONE, 2014;9(3):e91206.
    Species: Mouse
    Sample Types: Tissue Homogenates
  99. IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection.
    Authors: McCarthy M, Zhu L, Procario M, Weinberg J
    Virology, 2014;456(0):259-67.
    Species: Mouse
    Sample Types: BALF
  100. Differential IL-10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction.
    Authors: Zhou H, Wang Y, Lian Q, Yang B, Ma Y, Wu X, Sun S, Liu Y, Sun B
    Eur J Immunol, 2014;44(5):1352-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  101. Subcomponent vaccine based on CTA1-DD adjuvant with incorporated UreB class II peptides stimulates protective Helicobacter pylori immunity.
    Authors: Nedrud J, Bagheri N, Schon K, Xin W, Bergroth H, Eliasson D, Lycke N
    PLoS ONE, 2013;8(12):e83321.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  102. Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection.
    Authors: Fattouh R, Guo C, Lam G, Gareau M, Ngan B, Glogauer M, Muise A, Brumell J
    PLoS ONE, 2013;8(4):e61629.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. 1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivo.
    Authors: Li B, Baylink D, Deb C, Zannetti C, Rajaallah F, Xing W, Walter M, Lau K, Qin X
    PLoS ONE, 2013;8(3):e58808.
    Species: Mouse
    Sample Types: Serum
  104. T1/ST2 promotes T helper 2 cell activation and polyfunctionality in bronchopulmonary mycosis.
    Authors: Piehler D, Grahnert A, Eschke M, Richter T, Kohler G, Stenzel W, Alber G
    Mucosal Immunol, 2013;6(2):405-14.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  105. Epithelial NF-kappaB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling.
    Authors: Tully J, Hoffman S, Lahue K, Nolin J, Anathy V, Lundblad L, Daphtary N, Aliyeva M, Black K, Dixon A, Poynter M, Irvin C, Janssen-Heininger Y
    J Immunol, 2013;191(12):5811-21.
    Species: Mouse
    Sample Types: Tissue Homogenates
  106. Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.
    Authors: van Voorhis, Michael, Knopp, Samantha, Julliard, Walker, Fechner, John H, Zhang, Xiaoji, Schauer, James J, Mezrich, Joshua D
    PLoS ONE, 2013;8(12):e82545.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  107. A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
    Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
    EMBO Mol Med, 2013;5(4):516-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  108. Nanogel-based PspA intranasal vaccine prevents invasive disease and nasal colonization by Streptococcus pneumoniae.
    Authors: Kong, Il Gyu, Sato, Ayuko, Yuki, Yoshikaz, Nochi, Tomonori, Takahashi, Haruko, Sawada, Shinichi, Mejima, Mio, Kurokawa, Shiho, Okada, Kazunari, Sato, Shintaro, Briles, David E, Kunisawa, Jun, Inoue, Yusuke, Yamamoto, Masafumi, Akiyoshi, Kazunari, Kiyono, Hiroshi
    Infect Immun, 2013;81(5):1625-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Preconditioning of microglia by alpha-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.
    Authors: Roodveldt C, Labrador-Garrido A, Gonzalez-Rey E, Lachaud C, Guilliams T, Fernandez-Montesinos R, Benitez-Rondan A, Robledo G, Hmadcha A, Delgado M, Dobson C, Pozo D
    PLoS ONE, 2013;8(11):e79160.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  110. Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
    Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
    Infect. Immun., 2012;80(1):100-9.
    Species: Mouse
    Sample Types: Serum
  111. LXR-mediated inhibition of CD4+ T helper cells.
    Authors: Solt L, Kamenecka T, Burris T
    PLoS ONE, 2012;7(9):e46615.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  112. Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection.
    Authors: Dubin PJ, Martz A, Eisenstatt JR, Fox MD, Logar A, Kolls JK
    Infect. Immun., 2012;80(1):398-409.
    Species: Mouse
    Sample Types: BALF
  113. Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice.
    Authors: Qiu Y, Davis M, Dayrit J, Hadd Z, Meister D, Osterholzer J, Williamson P, Olszewski M
    PLoS ONE, 2012;7(10):e47853.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  114. Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis.
    Authors: Serezani CH, Kane S, Collins L
    J. Immunol., 2012;189(2):906-15.
    Species: Mouse
    Sample Types: BALF
  115. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011;12(6):568-75.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  116. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
    Authors: Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA
    FASEB J., 2011;25(1):409-19.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  117. Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells.
    Authors: Notley CA, Brown MA, Wright GP, Ehrenstein MR
    J. Immunol., 2011;186(8):4967-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  118. IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs.
    Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H
    J. Immunol., 2011;188(3):1503-13.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  119. Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance.
    Authors: Breslow JM, Meissler JJ, Hartzell RR
    Infect. Immun., 2011;79(8):3317-27.
    Species: Mouse
    Sample Types: Tissue Secretion
  120. The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
    Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
    J. Immunol., 2011;186(9):5425-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  121. Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
    Authors: Nel HJ, Hams E, Saunders SP
    J. Immunol., 2011;186(8):4631-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  122. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
    Authors: Barber DL, Mayer-Barber KD, Feng CG
    J. Immunol., 2011;186(3):1598-607.
    Species: Mouse
    Sample Types: BALF
  123. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.
    Authors: Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS
    J. Clin. Invest., 2010;120(5):1762-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  124. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
    Authors: Jones GW, McLoughlin RM, Hammond VJ, Parker CR, Williams JD, Malhotra R, Scheller J, Williams AS, Rose-John S, Topley N, Jones SA
    J. Immunol., 2010;184(4):2130-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells.
    Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM
    Brain Behav. Immun., 2010;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  126. Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
    Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
    J. Immunol., 2010;184(4):2076-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  127. Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice.
    Authors: Motz GT, Eppert BL, Wesselkamper SC, Flury JL, Borchers MT
    Am. J. Respir. Crit. Care Med., 2010;181(11):1223-33.
    Species: Mouse
    Sample Types: BALF
  128. Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
    Authors: Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
    Eur. J. Immunol., 2010;40(8):2221-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  129. A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
    Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
    J. Immunol., 2010;185(11):6741-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  130. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009;21(5):555-65.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  131. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.
    Authors: Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y
    Immunity, 2009;30(1):108-19.
    Species: Mouse
    Sample Types: Whole Tissue
  132. CCR5 is involved in resolution of inflammation in proteoglycan-induced arthritis.
    Authors: Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Kobezda T, Finnegan A
    Arthritis Rheum., 2009;60(10):2945-53.
    Species: Mouse
    Sample Types: Synovial Fluid
  133. CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
    Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
    J. Immunol., 2009;182(1):111-20.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  134. Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells.
    Authors: Nakamura R, Shibata K, Yamada H, Shimoda K, Nakayama K, Yoshikai Y
    J. Immunol., 2008;181(3):2071-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  135. Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17.
    Authors: Schulz SM, Kohler G, Schutze N, Knauer J, Straubinger RK, Chackerian AA, Witte E, Wolk K, Sabat R, Iwakura Y, Holscher C, Muller U, Kastelein RA, Alber G
    J. Immunol., 2008;181(11):7891-901.
    Species: Mouse
    Sample Types: Serum
  136. Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities.
    Authors: Rickel EA, Siegel LA, Yoon BR, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL
    J. Immunol., 2008;181(6):4299-310.
    Species: Mouse
    Sample Types: BALF
  137. Interferon-gamma regulates idiopathic pneumonia syndrome, a Th17+CD4+ T-cell-mediated graft-versus-host disease.
    Authors: Mauermann N, Burian J, von Garnier C, Dirnhofer S, Germano D, Schuett C, Tamm M, Bingisser R, Eriksson U, Hunziker L
    Am. J. Respir. Crit. Care Med., 2008;178(4):379-88.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
    Authors: Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
    Biochem. Biophys. Res. Commun., 2008;373(3):397-402.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  139. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
    Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
    J. Immunol., 2008;180(6):4022-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
    Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
    Circulation, 2008;118(20):2063-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. CD8+ T cells are not required for vaccine-induced immunity against Leishmania amazonensis in IL-12/23P40(-/-) C57BL/6 mice.
    Authors: Hernandez Sanabria MX, Afonso LC, Golgher D, Tafuri WL, Vieira LQ
    Microbes Infect., 2007;9(9):1124-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  142. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production.
    Authors: Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y
    J. Immunol., 2007;178(7):4466-72.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  143. IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice.
    Authors: Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K
    J. Immunol., 2007;179(12):8274-9.
    Species: Mouse
    Sample Types: Serum
  144. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007;26(4):445-59.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity.
    Authors: Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE
    J. Immunol., 2007;178(3):1341-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  146. Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis.
    Authors: Fitzgerald DC, Ciric B, Touil T, Harle H, Grammatikopolou J, Das Sarma J, Gran B, Zhang GX, Rostami A
    J. Immunol., 2007;179(5):3268-75.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  147. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.
    Authors: Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A
    Nat. Immunol., 2007;8(12):1372-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  148. Interleukin-17 is a negative regulator of established allergic asthma.
    Authors: Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B
    J. Exp. Med., 2006;203(12):2715-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates

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Mouse IL-17 DuoSet ELISA
By Anonymous on 06/11/2020
Application: Sample Tested: Mouse spleenocytes,Cell culture supernatant

The levels of IL-17 from culture supernatants of mouse spleen cells incubated with or without A reagent (group A) were measured with IL-17


Mouse IL-17 DuoSet ELISA
By Anonymous on 03/16/2020
Application: Sample Tested: Cell Culture Media

Mouse IL-17 DuoSet ELISA
By Anonymous on 01/25/2020
Application: Sample Tested: Mouse spleenocytes

Mouse IL-17 DuoSet ELISA
By Anonymous on 08/10/2019
Application: Sample Tested: Cell Lysates

Mouse IL-17 DuoSet ELISA
By Anonymous on 10/08/2018
Application: Sample Tested: Adult lung

Mouse IL-17 DuoSet ELISA
By Anonymous on 02/27/2018
Application: Sample Tested: Mouse TH-17 CELLS

Mouse IL-17 DuoSet ELISA
By Anonymous on 05/16/2017
Application: Sample Tested: Serum

Mouse IL-17 DuoSet ELISA
By Anonymous on 06/03/2016
Application: Sample Tested: Mouse splenocytes,mouse liver tissue,Mouse granulocytes,Mouse bone marrow derived dendritic cells

Mouse IL-17 DuoSet ELISA, 15 Plate
By Anonymous on 04/08/2016
Application: Sample Tested: murine lung homogenate

happy with product - consistent results, easy to use


Mouse IL-17 DuoSet ELISA, 15 Plate
By Anonymous on 10/26/2015
Application: Sample Tested: Lymphocytes (ex vivo)

Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: Reagent diluent
Dilution: 400 ng/mL (detection)


Mouse IL-17 DuoSet ELISA, 15 Plate
By Anonymous on 10/26/2015
Application: Sample Tested: In vitro derived lymphocytes

Specificity: Specific
Sensitivity: Sensitive
Buffer: 0.1% BSA, 0.05% Tween 20 in Tris-buffered Saline (20 mM Trizma base, 150 mM NaCl), pH 7.2 - 7.4, filtered
Dilution: 1/180