Mouse IL-24 Antibody Summary
Arg27-His181
Accession # NP_444325
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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IL‑24 in Mouse Splenocytes. IL-24 was detected in immersion fixed mouse splenocytes using Rat Anti-Mouse IL-24 Monoclonal Antibody (Catalog # MAB2786) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the Northern-Lights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IL-24
Mouse IL-24, also known as melanoma differentiation-associated gene 7 (MDA-7) and Th2-specific cytokine FISP, is a 27 kDa secreted glycoprotein that is a member of the IL-10 family. It is synthesized as a precursor with a large pro-region that is removed to generate a 155 aa mature protein. Mature mouse IL-24 shares 84% and 69% amino acid identity with rat and human IL-24, respectively.
Product Datasheets
Citations for Mouse IL-24 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 6
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IL-24 intrinsically regulates Th17 cell pathogenicity in mice
Authors: Christopher Sie, Ravi Kant, Christian Peter, Andreas Muschaweckh, Monika Pfaller, Lucy Nirschl et al.
Journal of Experimental Medicine
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CD4+ T helper 2 cell-macrophage crosstalk induces IL-24-mediated breast cancer suppression
Authors: Wang, B;Xia, Y;Zhou, C;Zeng, Y;Son, HG;Demehri, S;
JCI insight
Species: Mouse
Sample Types:
Applications: Immunofluorescence -
IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages
Authors: LZ Rao, Y Wang, L Zhang, G Wu, L Zhang, FX Wang, LM Chen, F Sun, S Jia, S Zhang, Q Yu, JH Wei, HR Lei, T Yuan, J Li, X Huang, B Cheng, J Zhao, Y Xu, BW Mo, CY Wang, H Zhang
Cell Death Differ, 2020-11-03;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in Rats
Authors: CY Chang, HJ Shih, IT Huang, PS Tsai, KY Chen, CJ Huang
Int J Mol Sci, 2019-09-18;20(18):.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC-P -
Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine
Authors: AR Burmeister, MB Johnson, JJ Yaemmongko, I Marriott
J Neuroinflammation, 2019-03-02;16(1):55.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot -
Dysregulation of suppressor of cytokine signaling 3 in keratinocytes causes skin inflammation mediated by interleukin-20 receptor-related cytokines.
Authors: Uto-Konomi A, Miyauchi K, Ozaki N
PLoS ONE, 2012-07-05;7(7):e40343.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr
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