Mouse Laminin alpha 1 / beta 1 Antibody
Mouse Laminin alpha 1 / beta 1 Antibody Summary
Skubitz, A.P. et al. (1987) Exp. Cell Res. 173:349. This application was not tested by R&D Systems.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Laminin alpha 1/ beta 1 in Embryonic Mouse Decidua. Laminin alpha 1/ beta 1 was detected in immersion fixed frozen sections of embryonic mouse decidua (E10.5) using 10 µg/mL Rat Anti-Mouse Laminin alpha 1/ beta 1 Monoclonal Antibody (Catalog # MAB4656) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Laminin alpha 1/ beta 1 in Mouse Kidney, Skin, Intestine, and Skeletal Muscle. Laminin alpha 1/ beta 1 was detected in perfusion fixed frozen sections of mouse kidney glomeruli (panel A), skin (panel B), intestine (panel C), and skeletal muscle (panel D) using Rat Anti-Mouse Laminin alpha 1/ beta 1 Monoclonal Antibody (Catalog # MAB4656) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Laminin alpha 1
Laminins are heterotrimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. Through interactions with integrins, dystroglycan, and other receptors, Laminins contribute to cell differentation, cell shape and migration, maintenance of tissue phenotypes, and survival. Laminin-1 is comprised of alpha 1, beta 1, and gamma 1 subunits.
Citations for Mouse Laminin alpha 1 / beta 1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Identification of the niche and mobilization mechanism for tissue-protective multipotential bone marrow ILC progenitors
Authors: Q Liu, JH Lee, HM Kang, CH Kim
Science Advances, 2022-11-23;8(47):eabq1551.
Species: Transgenic Mouse
Sample Types: Whole Tissue
Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160
Authors: A Perrin, J Rousseau, JP Tremblay
Mol Ther Nucleic Acids, 2016-12-10;6(0):68-79.
Sample Types: Cell Lysates, Whole Cells, Whole Tissue
Applications: ICC, IHC, Western Blot
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