Mouse Orexin R2/HCRTR2 (NP_945200) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Mouse Orexin R2/HCRTR2 (NP_945200) VersaClone cDNA Summary

Hypocretin receptor 2 (HCRTR2); also known as orexin receptor 2 or OX2R is a 40 kDa 7-transmembrane G-protein-coupled glycoprotein that is a high affinity receptor for orexins A and B (hypocretins 1 and 2). In mouse brain, engagement of HCRTRs promotes wakefulness, such that absence of either orexins or their receptors creates a narcolepsy-like state. HCRTR2 also influences reward circuits involving food or addictive drugs. The extracellular portions of human HCRTR2 share 92% and 93% aa identity with corresponding portions of mouse and rat HCRTR2, respectively.


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Product Datasheets

Background: Orexin R2/HCRTR2

Long Name
Hypocretin Receptor Type 2
Entrez Gene IDs
3062 (Human); 387285 (Mouse); 25605 (Rat)
Alternate Names
HCRTR2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2; Orexin R2; Orexin Receptor 2; orexin receptor type 2; OrexinR2; OX2R; Ox-2-R; ox2-R


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