Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit

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Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Cell Culture Supernate Standard Curve
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Product Details
Citations (226)
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Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit Summary

Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Serum (40 uL), EDTA Plasma (40 uL), Heparin Plasma (40 uL)
Sensitivity
15.4 pg/mL
Assay Range
31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Specificity
Natural and recombinant TGF-beta 1. This kit also recognizes human TGF-beta 1.2.
Cross-reactivity
Cross-reactivity observed with 1 or more available related molecules.Cross-species reactivity not tested.
Interference
Interference observed with 1 or more available related molecules.

Product Summary

The Quantikine Mouse/Rat/Porcine/Canine TGF-beta 1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TGF-beta 1 in acid activated cell culture supernates, serum, and plasma. It contains recombinant TGF-beta 1 expressed by CHO cells and has been shown to quantitate the recombinant factor accurately. Results obtained using natural TGF-beta 1 showed linear curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit will provide accurate quantitation for both recombinant and natural TGF-beta 1.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 22 21 22
Mean 88 198 816 97 209 826
Standard Deviation 3 4.9 19.6 8.1 17.3 47
CV% 3.4 2.5 2.4 8.4 8.3 5.7

Serum, EDTA Plasma, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 28 37 30
Mean 78 180 695 79 185 730
Standard Deviation 2.3 3.4 17.3 7.2 17.2 46.8
CV% 2.9 1.9 2.5 9.1 9.3 6.4

Recovery

The recovery of TGF-beta 1 spiked to levels throughout the range of the assay followed by activation was evaluated.

Sample Type Average % Recovery Range %
Mouse Cell Culture Supernates (n=4) 105 83-114
Porcine Cell Culture Supernates (n=2) 109 102-118
Rat Cell Culture Supernates (n=3) 112 93-125

Linearity

To assess the linearity of the assay, the activated samples containing and/or spiked with high concentrations of TGF-beta 1 were diluted with Calibrator Diluent and then assayed.
Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Linearity
Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Linearity
Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Linearity
Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Linearity

Data Examples

Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Cell Culture Supernate Standard Curve

Mouse/Rat/Porcine/Canine TGF-beta 1 ELISA Serum/Plasma Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 degreesC. Do not use past expiration date.

Background: TGF-beta 1

Transforming growth factor beta (TGF-beta ) proteins (including the three closely related mammalian isoforms TGF-beta 1, -2 and -3) are pleiotropic cytokines that regulate extracellular matrix production, wound healing, immune functions, cell proliferation and differentiation. They belong to the large TGF-beta superfamily, which also includes the activins/inhibins/MIS, bone morphogenetic proteins (BMPs), growth/differentiation factors (GDFs), Lefty1 and 2, and the distantly related GDNF family of neurotrophic factors. All family members show a characteristic cysteine-knot that is formed from multiple intrachain disulfide bonds (1-3). The mouse, rat, porcine and canine TGF-beta 1 cDNAs encode a 390 amino acid (aa) residue precursor that contains a 29 aa signal peptide and a 361 aa pro-protein. The pro-protein for each species is proteolytically processed via a furin-like convertase to generate an N-terminal 249 aa latency-associated peptide (LAP), and a C-terminal 112 aa mature TGF-beta 1 (4-9). Both LAP and mature TGF-beta 1 exist as disulfide-linked homodimers. After proteolytic cleavage and secretion, the two homodimers remain non-covalently associated as the small latent TGF-beta 1 complex. In most cell types, this complex is also covalently linked via LAP to a latent TGF-beta binding protein (LTBP). This creates a secreted, large latent complex. The TGF-beta 1 present in either the small or the large latent complex is not available for TGF-beta receptor binding and activation, and is, therefore, latent. Whereas LAP is both necessary and sufficient to confer latency to TGF-beta 1, LTBP facilitates the proper folding and secretion of the small latent complex. LTBP is also a structural component of the extracellular matrix and directs the localization of the latent complex to the extracellular matrix (10-15). To date, four LTBPs that share multiple EGF-like, LTBP- and fibrillin-specific domains have been cloned. Three of the four LTBPs (#1, 3, and 4) have been shown to bind the small latent complexes of all TGF-beta isoforms (16). Activation of the latent TGF-beta complex is an important step that regulates TGF-beta function in vivo. Multiple activation mechanisms have been identified. These involve proteasedependent (plasmin and matrix metalloprotease) and protease-independent (binding of LAP to thrombospondin 1 or a subset of integrins) pathways (5, 15, 17-21). Mature mouse TGF-beta 1 shows 100% aa sequence identity to mature rat TGF-beta 1 (6, 7), and both rat and mouse TGF-beta 1 show 99% aa sequence identity with mature porcine, human, and canine TGF-beta 1 (4, 9, 22). Mature porcine TGF-beta 1 shows absolute identity to both mature human and canine TGF-beta 1. The signalling high-affinity receptor for TGF-beta 1 is a heteromeric complex consisting of a type I (TGF-beta RI) and a type II (TGF-beta RII) transmembrane serine/threonine kinase receptor. TGF-beta RII is a constitutively active kinase. Upon binding TGF-beta 1, it phosphorylates and activates the TGF-beta RI. In turn, TGF-beta RI phosphorylates and activates Smad proteins that regulate transcription. TGF-beta RI, alternatively named activin receptor-like kinase (ALK-5), is present in almost all cell types. Two other type I receptors, ALK-1 and ALK-2 have also been implicated as alternative partners for TGF-beta RII in the TGF-beta signalling receptor complex. Besides the type I and type II receptors, accessory receptors including the type III receptor, TGF-beta RIII (also known as betaglycan), and endoglin, which modulate TGF-beta responses, have been identified (2, 23-26).

Long Name:
Transforming Growth Factor beta 1
Entrez Gene IDs:
7040 (Human); 21803 (Mouse); 59086 (Rat); 397078 (Porcine); 100033900 (Equine)
Alternate Names:
CEDLAP; DPD1; latency-associated peptide; TGF beta; TGF beta1; TGFB; TGFB1; TGF-beta 1 protein; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1; transforming growth factor beta-1; transforming growth factor, beta 1
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Citations for Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

226 Citations: Showing 1 - 10
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  1. HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation
    Authors: W Wei, W Chen, N He
    Journal of Translational Medicine, 2021;19(1):258.
    Species: Mouse
    Sample Types: BALF
  2. Effects of protein malnutrition on haematopoietic regulatory activity of bone marrow mesenchymal stem cells
    Authors: AA Hastreiter, GG Dos Santos, EN Makiyama, EWC Santos, P Borelli, RA Fock
    The Journal of nutritional biochemistry, 2021;0(0):108626.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  3. Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients
    Authors: I Belinchón-, P Bellot, D Romero-Pér, I Herraiz-Ro, F Marco, R Frances, JM Ramos-Rinc
    Scientific Reports, 2021;11(1):8593.
    Species: Rat
    Sample Types: Serum
  4. Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization
    Authors: J Banga, D Srinivasan, CC Sun, CD Thompson, F Milletti, KS Huang, S Hamilton, S Song, AF Hoffman, YG Qin, B Matta, M LaPan, Q Guo, G Lu, D Li, H Qian, DR Bolin, L Liang, C Wartchow, J Qiu, M Downing, S Narula, N Fotouhi, JA DeMartino, SL Tan, G Chen, BJ Barnes
    Sci Adv, 2020;6(20):eaay1057.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGF&beta1 as regulators of hematopoietic ageing
    Authors: S Valletta, A Thomas, Y Meng, X Ren, R Drissen, H Sengül, C Di Genua, C Nerlov
    Nat Commun, 2020;11(1):4075.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice
    Authors: S Tsuji, E Di Martino, T Mukai, S Tsuji, T Murakami, RA Harris, K Blomgren, U Åden
    J Neuroinflammation, 2020;17(1):111.
    Species: Mouse
    Sample Types: Tissue Lysates
  7. Optimized platelet rich plasma releasate (O-rPRP) repairs galactosemia-induced ovarian follicular loss in rats by activating mTOR signaling and inhibiting apoptosis
    Authors: W El Bakly, M Medhat, M Shafei, R Tash, M Elrefai, Y Shoukry, NN Omar
    Heliyon, 2020;6(9):e05006.
    Species: Rat
    Sample Types: Plasma
  8. CSF1R signaling is a regulator of pathogenesis in progressive MS
    Authors: N Hagan, JL Kane, D Grover, L Woodworth, C Madore, J Saleh, J Sancho, J Liu, Y Li, J Proto, M Zelic, A Mahan, M Kothe, AA Scholte, M Fitzgerald, B Gisevius, A Haghikia, O Butovsky, D Ofengeim
    Cell Death Dis, 2020;11(10):904.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  9. CCL11 increases the proportion of CD4+CD25+Foxp3+ Treg cells and the production of IL?2 and TGF?&beta by CD4+ T�cells via the STAT5 signaling pathway
    Authors: R Wang, K Huang
    Mol Med Rep, 2020;0(0):.
    Species: Mouse
    Sample Types: Serum
  10. Autologous platelet-rich fibrin stimulates canine periodontal regeneration
    Authors: C Kornsuthis, N Pirarat, T Osathanon, C Kalpravidh
    Sci Rep, 2020;10(1):1850.
    Species: Canine
    Sample Types: Tissue Homogenates
  11. Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGF&beta/SMAD2 Pathway
    Authors: M Kato, F Takahashi, T Sato, Y Mitsuishi, K Tajima, H Ihara, F Nurwidya, H Baskoro, A Murakami, I Kobayashi, M Hidayat, N Shimada, S Sasaki, R Mineki, T Fujimura, T Kumasaka, SI Niwa, K Takahashi
    Drug Des Devel Ther, 2020;14(0):4593-4603.
    Species: Mouse
    Sample Types: BALF
  12. Mifepristone Treatment Promotes Testicular Leydig Cell Tumor Progression in Transgenic Mice
    Authors: D Ponikwicka, M Chrusciel, K Pulawska, P Bernaczyk, M Sztachelsk, P Guo, X Li, J Toppari, IT Huhtaniemi, S Wo?czy?ski, NA Rahman
    Cancers (Basel), 2020;12(11):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. TGF-&beta-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model
    Authors: DA Mázala, JS Novak, MW Hogarth, M Nearing, P Adusumalli, CB Tully, NF Habib, H Gordish-Dr, YW Chen, JK Jaiswal, TA Partridge
    JCI Insight, 2020;5(6):.
    Species: Mouse
    Sample Types: Tissue Lysates
  14. Propranolol Suppresses the T-Helper Cell Depletion-Related Immune Dysfunction in Cirrhotic Mice
    Authors: HC Tsai, CF Hsu, CC Huang, SF Huang, TH Li, YY Yang, MW Lin, TY Lee, CW Liu, YH Huang, MC Hou, HC Lin
    Cells, 2020;9(3):.
    Species: Mouse
    Sample Types: Plasma
  15. Beneficial effects of N-acetylcysteine on protease-antiprotease balance in attenuating bleomycin-induced pulmonary fibrosis in rats
    Authors: R Kulshresth, A Pandey, A Jaggi, S Bansal
    Iran J Basic Med Sci, 2020;23(3):396-405.
    Species: Rat
    Sample Types: Tissue Homogenates
  16. Yeast Cell wall Particle mediated Nanotube-RNA delivery system loaded with miR365 Antagomir for Post-traumatic Osteoarthritis Therapy via Oral Route
    Authors: L Zhang, H Peng, W Zhang, Y Li, L Liu, T Leng
    Theranostics, 2020;10(19):8479-8493.
    Species: Mouse
    Sample Types: Serum
  17. Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model
    Authors: Q Liang, Q Lin, Y Li, W Luo, X Huang, Y Jiang, C Qin, J Nong, X Chen, SR Sooranna, L Pinhu
    Journal of Immunology Research, 2020;2020(0):6644687.
    Species: Rat
    Sample Types: Serum
  18. The Impact of Focused Ultrasound in Two Tumor Models: Temporal Alterations in the Natural History on Tumor Microenvironment and Immune Cell Response
    Authors: G Cohen, P Chandran, RM Lorsung, LE Tomlinson, M Sundby, SR Burks, JA Frank
    Cancers (Basel), 2020;12(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta
    Authors: DM Karageorgi, DI Tsilimigra, P Selemenaki, V Vlachou, AL de Lastic, M Rodi, D Chatziatha, K Savvatakis, N Antoniou, AC Deli, A Papalampro, KA Filis, A Mouzaki, A Varvarigou, G Zografos, VG Gorgoulis, IS Pateras, F Sigala
    Sci Rep, 2020;10(1):5040.
    Species: Rat
    Sample Types: Cell Culture Lysates
  20. Low-protein diets supplemented with casein hydrolysate favor the microbiota and enhance the mucosal humoral immunity in the colon of pigs
    Authors: H Wang, J Shen, Y Pi, K Gao, W Zhu
    J Anim Sci Biotechnol, 2019;10(0):79.
    Species: Porcine
    Sample Types: Tissue Homogenates
  21. Curcumin ameliorates peritoneal fibrosis via inhibition of transforming growth factor-activated kinase 1 (TAK1) pathway in a rat model of peritoneal dialysis
    Authors: JL Zhao, T Zhang, X Shao, JJ Zhu, MZ Guo
    BMC Complement Altern Med, 2019;19(1):280.
    Species: Rat
    Sample Types: Peritoneal Fluid
  22. Der p2?A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis
    Authors: W Hu, L Ma, G Yang, X Zeng, J Liu, B Cheng, T Hu, H Zhao, Z Liu
    Mol Med Rep, 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  23. mTORC1-mediated polarization of M1 macrophages and their accumulation in the liver correlate with immunopathology in fatal ehrlichiosis
    Authors: M Haloul, ERA Oliveira, M Kader, JZ Wells, TR Tominello, A El Andalou, CC Yates, N Ismail
    Sci Rep, 2019;9(1):14050.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  24. Antifibrotic effects of gallic acid on hepatic stellate cells: In�vitro and in�vivo mechanistic study
    Authors: NM El-Lakkany, WH El-Maadawy, SH Seif El-Di, S Saleh, MM Safar, SM Ezzat, SH Mohamed, SS Botros, Z Demerdash, OA Hammam
    J Tradit Complement Med, 2019;9(1):45-53.
    Species: Rat
    Sample Types: Tissue Homogenates
  25. Mesenchymal stem cell-derived conditioned medium attenuate angiotensin II-induced aortic aneurysm growth by modulating macrophage polarization
    Authors: YZ Zhou, Z Cheng, Y Wu, QY Wu, XB Liao, Y Zhao, JM Li, XM Zhou, XM Fu
    J. Cell. Mol. Med., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  26. Computational/experimental evaluation of liver metastasis post hepatic injury: interactions with macrophages and transitional ECM
    Authors: SV Hudson, HA Miller, GE Mahlbacher, D Saforo, LJ Beverly, GE Arteel, HB Frieboes
    Sci Rep, 2019;9(1):15077.
    Species: Mouse
    Sample Types: Cell Culture Superantes
  27. IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis
    Authors: M Liang, Q Ma, N Ding, F Luo, Y Bai, F Kang, X Gong, R Dong, J Dai, Q Dai, C Dou, S Dong
    Cell Death Dis, 2019;10(5):353.
    Species: Mouse
    Sample Types: Serum
  28. Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model
    Authors: B Wu, XY Huang, L Li, XH Fan, PC Li, CQ Huang, J Xiao, R Gui, S Wang
    J. Cell. Mol. Med., 2019;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  29. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation
    Authors: N Uyama, H Tsutsui, S Wu, K Yasuda, E Hatano, XY Qin, S Kojima, J Fujimoto
    Sci Rep, 2019;9(1):17558.
    Species: Mouse
    Sample Types: Serum
  30. Investigation of Conjunctival Fibrosis Response Using a 3D Glaucoma Tenon's Capsule + Conjunctival Model
    Authors: R Gater, T Ipek, S Sadiq, D Nguyen, L Jones, A El Haj, Y Yang
    Invest. Ophthalmol. Vis. Sci., 2019;60(2):605-614.
    Species: Porcine
    Sample Types: Aqueous Humor
  31. Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection
    Authors: E Picarda, S Bézie, L Usero, J Ossart, M Besnard, H Halim, K Echasserie, C Usal, J Rossjohn, K Bernardeau, S Gras, C Guillonnea
    Cell Rep, 2019;29(13):4245-4255.e6.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. The JAK2/STAT3 signaling pathway is required for inflammation and cell death induced by cerulein in AR42J cells
    Authors: WD Chen, JL Zhang, XY Wang, ZW Hu, YB Qian
    Eur Rev Med Pharmacol Sci, 2019;23(4):1770-1777.
    Species: Rat
    Sample Types: Cell Culture Supernates
  33. Prophylactic efficacy of Quercetin in ameliorating the hypoxia induced vascular leakage in lungs of rats
    Authors: A Tripathi, B Kumar, SSK Sagi
    PLoS ONE, 2019;14(6):e0219075.
    Species: Rat
    Sample Types: BALF
  34. Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
    Authors: A Oppezzo, J Bourseguin, E Renaud, P Pawlikowsk, F Rosselli
    J. Clin. Invest., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  35. 1,25?Dihydroxy?Vitamin D3 induces macrophage polarization to M2 by upregulating T?cell Ig?mucin?3 expression
    Authors: S Liang, J Cai, Y Li, R Yang
    Mol Med Rep, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  36. Dendropanax morbifera Ameliorates Thioacetamide-Induced Hepatic Fibrosis via TGF-?1/Smads Pathways
    Authors: HY Yang, KS Kim, YH Lee, JH Park, JH Kim, SY Lee, YM Kim, IS Kim, S Kacew, BM Lee, JH Kwak, K Yoon, HS Kim
    Int. J. Biol. Sci., 2019;15(4):800-811.
    Species: Rat
    Sample Types: Serum
  37. The protective effects of Berberine and Hesperidin on inflammatory factor-stimulating cardiac fibroblasts
    Authors: XH Yu, YF Wang, FY Dai, JH Zhao, P Li
    Eur Rev Med Pharmacol Sci, 2019;23(12):5468-5476.
    Species: Rat
    Sample Types: Cell Culture Supernates
  38. Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis
    Authors: Z Li, Y Lin, S Zhang, L Zhou, G Yan, Y Wang, M Zhang, M Wang, H Lin, Q Tong, Y Duan, G Du
    J Transl Med, 2019;17(1):90.
    Species: Mouse
    Sample Types: Alveolar Fluid
  39. GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain
    Authors: S Bang, YK Xie, ZJ Zhang, Z Wang, ZZ Xu, RR Ji
    J. Clin. Invest., 2018;128(8):3568-3582.
    Species: Mouse
    Sample Types: Tissue Homogenates
  40. Long-term treatment with anti-VEGF does not induce cell aging in primary retinal pigment epithelium
    Authors: J Schottler, N Randoll, R Lucius, A Caliebe, J Roider, A Klettner
    Exp. Eye Res., 2018;0(0):.
    Species: Porcine
    Sample Types: Cell Culture Supernates
  41. Knob protein enhances epithelial barrier integrity and attenuates airway inflammation
    Authors: SG Ha, M Dileepan, XN Ge, BN Kang, YG Greenberg, A Rao, G Muralidhar, L Medina-Kau, MA Thompson, CM Pabelick, SM O'Grady, SP Rao, P Sriramarao
    J. Allergy Clin. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
    Applications: ELISA Capture
  42. An insight into the role of magnesium in the immunomodulatory properties of mesenchymal stem cells
    Authors: F da Silva L, AB da Rocha R, A Hastreiter, A Nogueira-P, E Makiyama, C Colli, RA Fock
    J. Nutr. Biochem., 2018;55(0):200-208.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. Syndecan-1 inhibits early stages of liver fibrogenesis by interfering with TGF?1 action and upregulating MMP14
    Authors: E Reg?s, HH Abdelfatta, A Reszegi, L Szilák, K Werling, G Szabó, A Kiss, Z Schaff, I Kovalszky, K Baghy
    Matrix Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  44. Peroxisome proliferator-activated receptor-? and its related pathway in bone marrow mesenchymal stem cell differentiation co-cultured with mechanically stretched ligament fibroblasts
    Authors: B Zhao, M Hu, H Wu, C Ren, J Chen, X Zhang, S Cui
    Int. J. Mol. Med., 2018;0(0):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  45. Effects of 5-HT2receptor antagonists on bronchoconstriction and pulmonary remodeling processes
    Authors: A Löfdahl, C Wenglén, K Rydell-Tör, G Westergren, AK Larsson-Ca
    Am. J. Pathol., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  46. Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
    Authors: LC Dutton, J Dudhia, B Catchpole, H Hodgkiss-G, D Werling, DJ Connolly
    Sci Rep, 2018;8(1):13351.
    Species: Canine
    Sample Types: Cell Culture Supernates
  47. Liposomal Elongation Factor-1? Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis
    Authors: A Sabur, S Bhowmick, R Chhajer, SA Ejazi, N Didwania, M Asad, A Bhattachar, U Sinha, N Ali
    Front Immunol, 2018;9(0):18.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  48. The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium
    Authors: K Schlereth, D Weichenhan, T Bauer, T Heumann, E Giannakour, D Lipka, S Jaeger, M Schlesner, P Aloy, R Eils, C Plass, HG Augustin
    Elife, 2018;7(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  49. Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression
    Authors: MN Lee, HS Hwang, SH Oh, A Roshanzade, JW Kim, JH Song, ES Kim, JT Koh
    Exp. Mol. Med., 2018;50(11):142.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  50. Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma
    Authors: Y Okada, T Wang, K Kasai, K Suzuki, Y Takikawa
    Cell Death Discov, 2018;4(0):42.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. The dynamics of TGF-? in dental pulp, odontoblasts and dentin
    Authors: T Niwa, Y Yamakoshi, H Yamazaki, T Karakida, R Chiba, JC Hu, T Nagano, R Yamamoto, JP Simmer, HC Margolis, K Gomi
    Sci Rep, 2018;8(1):4450.
    Species: Mouse
    Sample Types: Hepatic Fluid Extracts
  52. Pirfenidone inhibits cryoablation induced local macrophage infiltration along with its associated TGFb1 expression and serum cytokine level in a mouse model
    Authors: Y Gu, G Srimathvee, L Cai, E Ueshima, M Maybody, H Yarmohamma, YS Zhu, JC Durack, SB Solomon, JA Coleman, JP Erinjeri
    Cryobiology, 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  53. TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
    Authors: H Wu, X Xu, J Li, J Gong, M Li
    Int. J. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  54. SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling
    Authors: L Jiang, X Han, J Wang, C Wang, X Sun, J Xie, G Wu, H Phan, Z Liu, C Zhang, M Zhao, X Kang
    J. Exp. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Bone Marrow
  55. Cardiac effects of fish oil in a rat model of streptozotocin-induced diabetes
    Authors: F Mayyas, R Jaradat, KH Alzoubi
    Nutr Metab Cardiovasc Dis, 2018;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  56. The local cytokine and growth factor response to rhBMP-2 after spinal fusion
    Authors: JD Koerner, DZ Markova, GD Schroeder, BP Calio, A Shah, CW Brooks, AR Vaccaro, DG Anderson, CK Kepler
    Spine J, 2018;0(0):.
    Species: Rat
    Sample Types: Tissue Lysates
    Applications: ELISA (Standard)
  57. Using the interplay of magnetic guidance and controlled TGF-? release from protein-based nanocapsules to stimulate chondrogenesis
    Authors: CS Chiang, JY Chen, MY Chiang, KT Hou, WM Li, SJ Chang, SY Chen
    Int J Nanomedicine, 2018;13(0):3177-3188.
    Species: Mouse
    Sample Types: Complex Sample Type
  58. Acute lung injury by gastric fluid instillation: activation of myofibroblast apoptosis during injury resolution
    Authors: P Ayala, J Torres, R Vivar, M Meneses, P Olmos, T San Martin, GR Borzone
    Respir. Res., 2018;19(1):57.
    Species: Mouse
    Sample Types: BALF
  59. Tumor-independent host secretomes induced by angiogenesis and immune-checkpoint inhibitors
    Authors: M Mastri, CR Lee, A Tracz, RS Kerbel, M Dolan, Y Shi, JML Ebos
    Mol. Cancer Ther., 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  60. CERA Attenuates Kidney Fibrogenesis in the db/db Mouse by Influencing the Renal Myofibroblast Generation
    Authors: C Fischer, N Deininger, G Wolf, I Loeffler
    J Clin Med, 2018;7(2):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  61. IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo
    Authors: M Boieri, A Ulvmoen, A Sudworth, C Lendrem, M Collin, AM Dickinson, L Kveberg, M Inngjerdin
    Oncoimmunology, 2017;6(3):e1274478.
    Species: Rat
    Sample Types: Serum
  62. Umbilical cord-derived mesenchymal stem cell extracts reduce colitis in mice by re-polarizing intestinal macrophages
    Authors: JY Song, HJ Kang, JS Hong, CJ Kim, JY Shim, CW Lee, J Choi
    Sci Rep, 2017;7(1):9412.
    Species: Mouse
    Sample Types: Tissue Homogenates
  63. Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis
    Authors: NM El-Lakkany, WH El-Maadawy, SH Seif El-Di, OA Hammam, SH Mohamed, SM Ezzat, MM Safar, S Saleh
    Asian Pac J Trop Med, 2017;10(5):444-453.
    Species: Rat
    Sample Types: Tissue Homogenates
  64. Attenuating the rate of total body fat accumulation and alleviating liver damage by oral administration of vitamin D-enriched edible mushrooms in a diet-induced obesity murine model is mediated by an anti-inflammatory paradigm shift
    Authors: A Drori, D Rotnemer-G, S Avni, A Drori, O Danay, D Levanon, J Tam, L Zolotarev, Y Ilan
    BMC Gastroenterol, 2017;17(1):130.
    Species: Mouse
    Sample Types: Serum
  65. Validation of commercial ELISAs for quantifying anabolic growth factors and cytokines in canine ACD-A anticoagulated plasma
    Authors: K Birdwhiste, R Basinger, B Hayes, N Norton, DJ Hurley, SP Franklin
    J. Vet. Diagn. Invest, 2017;0(0):1040638717690.
    Species: Canine
    Sample Types: Plasma
  66. Scavenging of reactive oxygen species by astaxanthin inhibits epithelial-mesenchymal transition in high glucose-stimulated mesothelial cells
    Authors: K Hara, C Hamada, K Wakabayash, R Kanda, K Kaneko, S Horikoshi, Y Tomino, Y Suzuki
    PLoS ONE, 2017;12(9):e0184332.
    Species: Rat
    Sample Types: Cell Culture Supernates
  67. Tenascin-C expression and its associated pathway in BMSCs following co-culture with mechanically stretched ligament fibroblasts
    Authors: B Zhao, M Hu, H Wu, C Ren, J Wang, S Cui
    Mol Med Rep, 2017;15(5):2465-2472.
    Species: Rat
    Sample Types: Cell Culture Supernates
  68. Lipoxin A4 encapsulated in PLGA microparticles accelerates wound healing of skin ulcers
    Authors: MB Reis, PAT Pereira, GF Caetano, MN Leite, AF Galvão, FWG Paula-Silv, MAC Frade, LH Faccioli
    PLoS ONE, 2017;12(7):e0182381.
    Species: Rat
    Sample Types: Tissue Homogenates
  69. Changes in skin structure of the Zip13-KO mouse by Makomo (Zizania latifolia) feeding
    Authors: T Yamauchi, T Hirose, K Sato, K Iwai, N Takahashi, J Minaguchi, T Ueno, P Tangkawatt, K Takehana
    J. Vet. Med. Sci., 2017;0(0):.
    Species: Mouse
    Sample Types: Plasma
  70. Influence of Cellular Composition and Exogenous Activation on Growth Factor and Cytokine Concentrations in Canine Platelet-Rich Plasmas
    Authors: SP Franklin, KE Birdwhiste, A Strelchik, BC Garner, BM Brainard
    Front Vet Sci, 2017;4(0):40.
    Species: Canine
    Sample Types: Platelet Rich Plasma (PRP)
  71. Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
    Authors: HJ Wu, JW Oh, DF Spandau, S Tholpady, J Diaz, LJ Schroeder, CD Offutt, AB Glick, MV Plikus, S Koyama, J Foley
    Development, 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  72. Enhanced antiviral and antifibrotic effects of short hairpin RNAs targeting HBV and TGF-? in HBV-persistent mice
    Authors: L Ye, F Kan, T Yan, J Cao, L Zhang, Z Wu, W Li
    Sci Rep, 2017;7(1):3860.
  73. Mesenteric lymph node stromal cell-derived extracellular vesicles contribute to peripheral de novo induction of Foxp3(+) regulatory T cells
    Authors: M Pasztoi, J Pezoldt, M Beckstette, C Lipps, D Wirth, M Rohde, K Paloczi, EI Buzas, J Huehn
    Eur. J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  74. Ablation of IL-17 expression moderates experimental autoimmune myasthenia gravis disease severity
    Authors: G Aguilo-Sea, Y Xie, J Sheehan, LL Kusner, HJ Kaminski
    Cytokine, 2017;96(0):279-285.
    Species: Mouse
    Sample Types: Serum
  75. A critical role of platelet TGF-? release in podoplanin-mediated tumour invasion and metastasis
    Authors: A Takemoto, M Okitaka, S Takagi, M Takami, S Sato, M Nishio, S Okumura, N Fujita
    Sci Rep, 2017;7(0):42186.
    Species: Human
    Sample Types: Cell Culture Supernates
  76. PPAR? Links BMP2 and TGF?1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism
    Authors: L Calvier, P Chouvarine, E Legchenko, N Hoffmann, J Geldner, P Borchert, D Jonigk, MM Mozes, G Hansmann
    Cell Metab., 2017;25(5):1118-1134.e7.
    Species: Mouse
    Sample Types: Plasma
  77. Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats
    Authors: N Liu, L Xu, Y Shi, L Fang, H Gu, H Wang, X Ding, S Zhuang
    Oncotarget, 2017;8(20):33807-33826.
    Species: Rat
    Sample Types: Tissue Culture Supernates
  78. Fungal immunomodulatory protein-fve could modulate airway remodel through by affect IL17 cytokine
    Authors: YT Lee, CT Wu, HL Sun, JL Ko, KH Lue
    J Microbiol Immunol Infect, 2017;0(0):.
    Species: Mouse
    Sample Types: BALF
  79. Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis
    PLoS ONE, 2016;11(12):e0163187.
    Species: Rat
    Sample Types: Cell Culture Supernates
  80. High Physiological Concentrations of Progesterone Reverse Estradiol-Mediated Changes in Differentiation and Functions of Bone Marrow Derived Dendritic Cells
    Authors: F Xiu, VC Anipindi, PV Nguyen, J Boudreau, H Liang, Y Wan, DP Snider, C Kaushic
    PLoS ONE, 2016;11(4):e0153304.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  81. An ENU-induced p.C225S missense mutation in the mouse Tgfb1 gene does not cause Camurati-Engelmann disease-like skeletal phenotypes
    Authors: Satoki Ichimura
    Exp. Anim, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  82. Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge
    PLoS ONE, 2016;11(8):e0161169.
    Species: Canine
    Sample Types: Cell Culture Supernates
  83. Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
    Sci Rep, 2016;6(0):36077.
    Species: Rat
    Sample Types: Cell Culture Supernates
  84. TGF-?1 autocrine signalling and enamel matrix components
    Sci Rep, 2016;6(0):33644.
    Species: Porcine
    Sample Types:
  85. Freeze-Dried Platelet-Rich Plasma Accelerates Bone Union with Adequate Rigidity in Posterolateral Lumbar Fusion Surgery Model in Rats
    Sci Rep, 2016;6(0):36715.
    Species: Rat
    Sample Types: Plasma
  86. TGF-? and Physiological Root Resorption of Deciduous Teeth
    Int J Mol Sci, 2016;18(1):.
    Species: Porcine
    Sample Types: Tissue Homogenates
  87. Molecular and Microarray-based Analysis of Diversity among Resting and Osteogenically Induced Porcine Mesenchymal Stromal Cells of Several Tissue Origin
    Authors: Samet Bayraktar
    J Tissue Eng Regen Med, 2016;0(0):.
    Species: Porcine
    Sample Types: Serum
  88. Inhibition of Interleukin 17-A but not Interleukin-17F Signaling Lowers Blood Pressure and Reduces End-organ Inflammation in Angiotensin II-induced Hypertension
    Authors: MA Saleh, AE Norlander, MS Madhur
    JACC Basic Transl Sci, 2016;1(7):606-616.
    Species: Mouse
    Sample Types: Tissue Homogenates
  89. Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution
    Nat Commun, 2016;7(0):12177.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  90. Modulation of the anti-inflammatory effects of phosphatidylserine-containing liposomes by PEGylation
    Authors: Hongxuan Quan
    J Biomed Mater Res A, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  91. CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage
    Sci Rep, 2016;6(0):26239.
    Species: Rat
    Sample Types: Serum
  92. Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function
    J Leukoc Biol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  93. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016;7(1):175.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  94. TGF-? Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions
    Authors: X Chen, DL Rateri, DA Howatt, A Balakrishn, JJ Moorleghen, LA Cassis, A Daugherty
    PLoS ONE, 2016;11(4):e0153811.
    Species: Mouse
    Sample Types: Serum
  95. Soluble Vascular Cell Adhesion Molecule-1 (VCAM-1) as a Biomarker in the Mouse Model of Experimental Autoimmune Myocarditis (EAM)
    PLoS ONE, 2016;11(8):e0158299.
    Species: Mouse
    Sample Types: Tissue Homogenates
  96. Pleural inhibition of the caspase-1/IL-1? pathway diminishes profibrotic lung toxicity of bleomycin
    Respir. Res, 2016;17(1):162.
    Species: Mouse
    Sample Types: Pleural Lavage Fluid
  97. Tolerogenic Phenotype of IFN-?-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop
    Authors: Qingsheng Li
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  98. Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells.
    Authors: Strobel B, Klauser B, Hartig J, Lamla T, Gantner F, Kreuz S
    Mol Ther, 2015;23(10):1582-91.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015;194(11):5407-16.
    Species: Mouse
    Sample Types: BALF
  100. Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR.
    Authors: Gregorini M, Corradetti V, Rocca C, Pattonieri E, Valsania T, Milanesi S, Serpieri N, Bedino G, Esposito P, Libetta C, Avanzini M, Mantelli M, Ingo D, Peressini S, Albertini R, Dal Canton A, Rampino T
    PLoS ONE, 2015;11(2):e0148542.
    Species: Rat
    Sample Types: Tissue Homogenates
  101. GP96 is a GARP chaperone and controls regulatory T cell functions.
    Authors: Zhang Y, Wu B, Metelli A, Thaxton J, Hong F, Rachidi S, Ansa-Addo E, Sun S, Vasu C, Yang Y, Liu B, Li Z
    J Clin Invest, 2015;125(2):859-69.
    Species: Mouse
    Sample Types: Serum
  102. Low TGFbeta1 expression prevents and high expression exacerbates diabetic nephropathy in mice.
    Authors: Hathaway C, Gasim A, Grant R, Chang A, Kim H, Madden V, Bagnell C, Jennette J, Smithies O, Kakoki M
    Proc Natl Acad Sci U S A, 2015;112(18):5815-20.
    Species: Mouse
    Sample Types: Plasma
  103. WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
    Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
    BMC Gastroenterol, 2015;15(0):173.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  104. AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by Smurf2 and deubiquitinating enzyme USP4.
    Authors: Xiao L, Peng X, Liu F, Tang C, Hu C, Xu X, Wang M, Luo Y, Yang S, Song P, Xiao P, Kanwar Y, Sun L
    BMC Cell Biol, 2015;16(0):7.
    Species: Mouse
    Sample Types: Peritoneal Dialysate
  105. Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.
    Authors: Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F
    PLoS ONE, 2015;10(4):e0124048.
    Species: Rat
    Sample Types: Serum
  106. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
    Authors: Charolidi N, Schilling T, Eder C
    PLoS ONE, 2015;10(5):e0128463.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  107. Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat.
    Authors: Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin D, Nakamura K, Honda M, Inoue K, Saito M
    PLoS ONE, 2015;10(8):e0133798.
    Species: Rat
    Sample Types: Tissue Homogenates
  108. MDSC and TGFbeta Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes.
    Authors: Shvedova A, Kisin E, Yanamala N, Tkach A, Gutkin D, Star A, Shurin G, Kagan V, Shurin M
    Cancer Res, 2015;75(8):1615-23.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Alcohol inhibits osteopontin-dependent transforming growth factor-beta1 expression in human mesenchymal stem cells.
    Authors: Driver J, Weber C, Callaci J, Kothari A, Zapf M, Roper P, Borys D, Franzen C, Gupta G, Wai P, Zhang J, Denning M, Kuo P, Mi Z
    J Biol Chem, 2015;290(16):9959-73.
    Species: Mouse
    Sample Types: Tissue Homogenates
  110. Transplanted neural stem cells modulate regulatory T, gammadelta T cells and corresponding cytokines after intracerebral hemorrhage in rats.
    Authors: Gao L, Lu Q, Huang L, Ruan L, Yang J, Huang W, ZhuGe W, Zhang Y, Fu B, Jin K, ZhuGe Q
    Int J Mol Sci, 2014;15(3):4431-41.
    Species: Rat
    Sample Types: Serum
  111. Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.
    Authors: Maneva-Radicheva L, Amatya C, Parker C, Ellefson J, Radichev I, Raghavan A, Charles M, Williams M, Robbins M, Savinov A
    PLoS ONE, 2014;9(9):e107213.
    Species: Mouse
    Sample Types: Serum
  112. Antitumor activity of total flavonoids from Tetrastigma hemsleyanum Diels et Gilg is associated with the inhibition of regulatory T cells in mice.
    Authors: Feng Z, Hao W, Lin X, Fan D, Zhou J
    Onco Targets Ther, 2014;7(0):947-56.
    Species: Mouse
    Sample Types: Serum
  113. Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10.
    Authors: Nitahara-Kasahara Y, Hayashita-Kinoh H, Chiyo T, Nishiyama A, Okada H, Takeda S, Okada T
    Hum Mol Genet, 2014;23(15):3990-4000.
    Species: Mouse
    Sample Types: Tissue Homogenates
  114. Magnetic resonance colonography for fibrosis assessment in rats with chronic colitis.
    Authors: Melchior C, Loeuillard E, Marion-Letellier R, Nicol L, Mulder P, Guerin C, Bole-Feysot C, Aziz M, Dechelotte P, Vera P, Savoye G, Savoye-Collet C
    PLoS ONE, 2014;9(7):e100921.
    Species: Rat
    Sample Types: Tissue Homogenates
  115. Activin A induces growth arrest through a SMAD- dependent pathway in hepatic progenitor cells.
    Authors: Chen L, Zhang W, Liang H, Zhou Q, Ding Z, Yang H, Liu W, Wu Y, Man Q, Zhang B, Chen X
    Cell Commun Signal, 2014;12(0):18.
    Species: Rat
    Sample Types: Cell Culture Supernates
  116. Time-dependent and somatically acquired mitochondrial DNA mutagenesis and respiratory chain dysfunction in a scleroderma model of lung fibrosis.
    Authors: Gazdhar A, Lebrecht D, Roth M, Tamm M, Venhoff N, Foocharoen C, Geiser T, Walker U
    Sci Rep, 2014;4(0):5336.
    Species: Rat
    Sample Types: Tissue Homogenates
  117. The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis.
    Authors: Zhang L, Hao J, Ren L, Ding J, Hao L
    Lab Invest, 2014;94(8):839-50.
    Species: Rat
    Sample Types: Abdominal Fluid
  118. Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury.
    Authors: Martin C, Zaman M, Gilkey C, Salguero M, Hasturk H, Kantarci A, Van Dyke T, Freedman S
    PLoS ONE, 2014;9(6):e98773.
    Species: Mouse
    Sample Types: Tissue Homogenates
  119. Oral administration of Lactobacillus plantarum strain AYA enhances IgA secretion and provides survival protection against influenza virus infection in mice.
    Authors: Kikuchi, Yosuke, Kunitoh-Asari, Ayami, Hayakawa, Katsuyuk, Imai, Shinjiro, Kasuya, Kenji, Abe, Kimio, Adachi, Yu, Fukudome, Shin-Ich, Takahashi, Yoshimas, Hachimura, Satoshi
    PLoS ONE, 2014;9(1):e86416.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  120. Prostatic ischemia induces ventral prostatic hyperplasia in the SHR; possible mechanism of development of BPH.
    Authors: Saito M, Tsounapi P, Oikawa R, Shimizu S, Honda M, Sejima T, Kinoshita Y, Tomita S
    Sci Rep, 2014;4(0):3822.
    Species: Rat
    Sample Types: Tissue Homogenates
  121. Integrin-mediated type II TGF-beta receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling.
    Authors: Chen X, Wang H, Liao H, Hu W, Gewin L, Mernaugh G, Zhang S, Zhang Z, Vega-Montoto L, Vanacore R, Fassler R, Zent R, Pozzi A
    J Clin Invest, 2014;124(8):3295-310.
    Species: Mouse
    Sample Types: Tissue Homogenates
  122. Role of Lactobacillus pentosus Strain b240 and the Toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin A enhancement.
    Authors: Kotani Y, Kunisawa J, Suzuki Y, Sato I, Saito T, Toba M, Kohda N, Kiyono H
    PLoS ONE, 2014;9(3):e91857.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  123. Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat.
    Authors: Lu Q, Gao L, Huang L, Ruan L, Yang J, Huang W, Li Z, Zhang Y, Jin K, ZhuGe Q
    J Neuroinflammation, 2014;11(0):44.
    Species: Rat
    Sample Types: Serum
  124. Mesenchymal stem cells from rats with chronic kidney disease exhibit premature senescence and loss of regenerative potential.
    Authors: Klinkhammer B, Kramann R, Mallau M, Makowska A, van Roeyen C, Rong S, Buecher E, Boor P, Kovacova K, Zok S, Denecke B, Stuettgen E, Otten S, Floege J, Kunter U
    PLoS ONE, 2014;9(3):e92115.
    Species: Rat
    Sample Types: Cell Culture Supernates
  125. Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma.
    Authors: Rydell-Tormanen K, Andreasson K, Hesselstrand R, Westergren-Thorsson G
    Sci Rep, 2014;4(0):6383.
    Species: Mouse
    Sample Types: Serum
  126. Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis.
    Authors: Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A
    J Immunol, 2014;193(5):2330-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  127. Expression of regulatory T cells in jejunum, colon, and cervical and mesenteric lymph nodes of dogs naturally infected with Leishmania infantum.
    Authors: Figueiredo M, Deoti B, Amorim I, Pinto A, Moraes A, Carvalho C, da Silva S, de Assis A, de Faria A, Tafuri W
    Infect Immun, 2014;82(9):3704-12.
    Species: Canine
    Sample Types: Tissue Homogenates
  128. Pivotal role of phospholipase D1 in tumor necrosis factor-alpha-mediated inflammation and scar formation after myocardial ischemia and reperfusion in mice.
    Authors: Schonberger T, Jurgens T, Muller J, Armbruster N, Niermann C, Gorressen S, Sommer J, Tian H, di Paolo G, Scheller J, Fischer J, Gawaz M, Elvers M
    Am J Pathol, 2014;184(9):2450-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  129. Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response.
    Authors: Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, Ukil A
    FASEB J, 2014;28(4):1756-68.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  130. Time-dependent expression profiles of microRNAs and mRNAs in rat milk whey.
    Authors: Izumi, Hirohisa, Kosaka, Nobuyosh, Shimizu, Takashi, Sekine, Kazunori, Ochiya, Takahiro, Takase, Mitsunor
    PLoS ONE, 2014;9(2):e88843.
    Species: Rat
    Sample Types: Serum
  131. Transforming growth factor-beta3 (TGF-beta3) knock-in ameliorates inflammation due to TGF-beta1 deficiency while promoting glucose tolerance.
    Authors: Hall B, Wankhade U, Konkel J, Cherukuri K, Nagineni C, Flanders K, Arany P, Chen W, Rane S, Kulkarni A
    J Biol Chem, 2013;288(44):32074-92.
    Species: Mouse
    Sample Types: Serum
  132. Antifibrotic effects of a recombinant adeno-associated virus carrying small interfering RNA targeting TIMP-1 in rat liver fibrosis.
    Authors: Cong M, Liu T, Wang P, Fan X, Yang A, Bai Y, Peng Z, Wu P, Tong X, Chen J, Li H, Cong R, Tang S, Wang B, Jia J, You H
    Am J Pathol, 2013;182(5):1607-16.
    Species: Rat
    Sample Types: Serum
  133. Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker.
    Authors: Nunes S, Soares E, Fernandes J, Viana S, Carvalho E, Pereira F, Reis F
    Cardiovasc Diabetol, 2013;12(0):44.
    Species: Rat
    Sample Types: Serum
  134. Conditional expression of TGF-beta1 in skeletal muscles causes endomysial fibrosis and myofibers atrophy.
    Authors: Narola J, Pandey S, Glick A, Chen Y
    PLoS ONE, 2013;8(11):e79356.
    Species: Mouse
    Sample Types: Tissue Homogenates
  135. Enhanced immunogenicity of a tricomponent mannan tetanus toxoid conjugate vaccine targeted to dendritic cells via Dectin-1 by incorporating beta-glucan.
    Authors: Lipinski T, Fitieh A, St Pierre J, Ostergaard H, Bundle D, Touret N
    J Immunol, 2013;190(8):4116-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses.
    Authors: Renson P, Le Dimna M, Keranflech A, Cariolet R, Koenen F, Le Potier M
    Vet Res, 2013;44(0):9.
    Species: Porcine
    Sample Types: Serum
  137. Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes.
    Authors: Cabrera S, Colvin S, Tersey S, Maier B, Nadler J, Mirmira R
    Clin Exp Immunol, 2013;172(3):375-82.
    Species: Mouse
    Sample Types: Serum
  138. Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
    Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
    PLoS ONE, 2013;8(11):e81090.
    Species: Mouse
    Sample Types: BALF
  139. FAK-related nonkinase is a multifunctional negative regulator of pulmonary fibrosis.
    Authors: Ding Q, Cai G, Hu M, Yang Y, Zheng A, Tang Q, Gladson C, Hayasaka H, Wu H, You Z, Southern B, Grove L, Rahaman S, Fang H, Olman M
    Am J Pathol, 2013;182(5):1572-84.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  140. The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone.
    Authors: Cho S, Pirih F, Koh A, Michalski M, Eber M, Ritchie K, Sinder B, Oh S, Al-Dujaili S, Lee J, Kozloff K, Danciu T, Wronski T, McCauley L
    J Biol Chem, 2013;288(10):6814-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. TLR-mediated distinct IFN-gamma/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.
    Eur. J. Immunol., 2012;42(8):2087-99.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  142. Comparison of the effect of calcium gluconate and batroxobin on the release of transforming growth factor beta 1 in canine platelet concentrates.
    Authors: Silva R, Carmona J, Rezende C
    BMC Vet Res, 2012;8(0):121.
    Species: Canine
    Sample Types: Plasma
  143. Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection.
    J. Virol., 2012;86(13):7060-71.
    Species: Mouse
    Sample Types: Serum
  144. Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis.
    Authors: Muller AM, Jun E, Conlon H, Sadiq SA
    BMC Neurosci, 2012;13(0):30.
    Species: Mouse
    Sample Types: Serum
  145. Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
    Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
    J. Biol. Chem., 2012;287(20):16356-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  146. Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
    Authors: Rau CR, Hein K, Sattler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bahr M
    Am. J. Pathol., 2012;178(4):1770-81.
    Species: Rat
    Sample Types: Tissue Homogenates
  147. Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency.
    Authors: Kawamura T, Ogawa Y, Nakamura Y
    J. Clin. Invest., 2012;122(2):722-32.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  148. Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
    Blood, 2012;120(13):2600-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  149. Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
    Authors: Diao J, Zhao J, Winter E
    J. Immunol., 2011;186(9):5058-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  150. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
    Authors: Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y
    J. Clin. Invest., 2011;121(11):4548-66.
    Species: Mouse
    Sample Types: Plasma
  151. Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function.
    Authors: Hall BE, Zheng C, Swaim WD, Cho A, Nagineni CN, Eckhaus MA, Flanders KC, Ambudkar IS, Baum BJ, Kulkarni AB
    Lab. Invest., 2011;90(4):543-55.
    Species: Mouse
    Sample Types: Serum
  152. Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells.
    Authors: Notley CA, Brown MA, Wright GP, Ehrenstein MR
    J. Immunol., 2011;186(8):4967-72.
    Species: Mouse
    Sample Types: Serum
  153. Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
    Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
    J. Immunol., 2011;186(12):7144-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  154. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2010;130(3):866-75.
    Species: Mouse
    Sample Types: Tissue Homogenates
  155. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
    Authors: Graham BB, Mentink-Kane MM, El-Haddad H
    Am. J. Pathol., 2010;177(3):1549-61.
    Species: Mouse
    Sample Types: Tissue Homogenates
  156. Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner.
    Authors: Cash JL, Christian AR, Greaves DR
    J. Immunol., 2010;184(9):5315-24.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  157. Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model.
    Authors: Shevalye H, Stavniichuk R, Xu W, Zhang J, Lupachyk S, Maksimchyk Y, Drel VR, Floyd EZ, Slusher B, Obrosova IG
    Biochem. Pharmacol., 2010;79(7):1007-14.
    Species: Rat
    Sample Types: Tissue Homogenates
  158. Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
    Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L67-78.
    Species: Mouse
    Sample Types: BALF
  159. Anti-Asthma Simplified Herbal Medicine Intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-gamma, but not transforming growth factor-beta dependent.
    Authors: Srivastava K, Zhang T, Yang N, Sampson H, Li XM
    Clin. Exp. Allergy, 2010;40(11):1678-88.
    Species: Mouse
    Sample Types: BALF
  160. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010;185(4):2502-15.
    Species: Mouse
    Sample Types: Serum
  161. Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.
    Authors: Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ
    Nat. Med., 2010;16(2):191-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  162. TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
    Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
    Species: Mouse
    Sample Types: BALF
  163. Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma.
    Authors: Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC
    Am. J. Respir. Cell Mol. Biol., 2009;40(3):349-58.
    Species: Mouse
    Sample Types: BALF
  164. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.
    Authors: Bhowmick S, Mazumdar T, Ali N
    Infect. Immun., 2009;77(4):1514-23.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  165. Loss of Thy-1 inhibits alveolar development in the newborn mouse lung.
    Authors: Nicola T, Hagood JS, James ML, Macewen MW, Williams TA, Hewitt MM, Schwiebert L, Bulger A, Oparil S, Chen YF, Ambalavanan N
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(5):L738-50.
    Species: Mouse
    Sample Types: Tissue Homogenates
  166. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009;21(5):555-65.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  167. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2009;21(1):81-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  168. Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.
    Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS
    J. Immunol., 2009;182(11):6907-14.
    Species: Mouse
    Sample Types: BALF
  169. Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.
    Authors: Koronyo-Hamaoui M, Ko MK, Koronyo Y, Azoulay D, Seksenyan A, Kunis G, Pham M, Bakhsheshian J, Rogeri P, Black KL, Farkas DL, Schwartz M
    J. Neurochem., 2009;111(6):1409-24.
    Species: Mouse
    Sample Types: Tissue Homogenates
  170. Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma.
    Authors: Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C, Gratziou C
    Am. J. Respir. Crit. Care Med., 2009;179(10):894-902.
    Species: Mouse
    Sample Types: Tissue Homogenates
  171. Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.
    Authors: Izumo T, Kondo M, Nagai A
    Eur. Respir. J., 2009;34(6):1444-51.
    Species: Mouse
    Sample Types: BALF
  172. Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy.
    Authors: Schuleri KH, Feigenbaum GS, Centola M, Weiss ES, Zimmet JM, Turney J, Kellner J, Zviman MM, Hatzistergos KE, Detrick B, Conte JV, McNiece I, Steenbergen C, Lardo AC, Hare JM
    Eur. Heart J., 2009;30(22):2722-32.
    Species: Porcine
    Sample Types: Serum
  173. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
    Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
    J. Neuroimmunol., 2009;208(1):54-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  174. Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy.
    Authors: Drel VR, Xu W, Zhang J, Pavlov IA, Shevalye H, Slusher B, Obrosova IG
    Endocrinology, 2009;150(12):5273-83.
    Species: Rat
    Sample Types: Tissue Homogenates
  175. Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function.
    Authors: Ishida Y, Gao JL, Murphy PM
    J. Immunol., 2008;180(1):569-79.
    Species: Mouse
    Sample Types: Tissue Homogenates
  176. Observations on the microvasculature of bone defects filled with biodegradable nanoparticulate hydroxyapatite.
    Authors: Kilian O, Wenisch S, Karnati S, Baumgart-Vogt E, Hild A, Fuhrmann R, Jonuleit T, Dingeldein E, Schnettler R, Franke RP
    Biomaterials, 2008;29(24):3429-37.
    Species: Porcine
    Sample Types: Plasma
  177. Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
    Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
    Eur. J. Immunol., 2008;38(10):2751-61.
    Species: Mouse
    Sample Types: BALF
  178. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
    Authors: Guo B, Chang EY, Cheng G
    J. Clin. Invest., 2008;118(5):1680-90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  179. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
    Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
    Am. J. Pathol., 2008;172(5):1209-21.
    Species: Mouse
    Sample Types: Tissue Homogenates
  180. IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
    Authors: Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA
    J. Immunol., 2008;180(1):522-9.
    Species: Mouse
    Sample Types: BALF
  181. A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis.
    Authors: Morschl E, Molina JG, Volmer JB, Mohsenin A, Pero RS, Hong JS, Kheradmand F, Lee JJ, Blackburn MR
    Am. J. Respir. Cell Mol. Biol., 2008;39(6):697-705.
    Species: Mouse
    Sample Types: BALF
  182. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008;590(1):400-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  183. Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.
    Authors: Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME
    Proc. Natl. Acad. Sci. U.S.A., 2008;105(20):7240-5.
    Species: Mouse
    Sample Types: BALF
  184. Molecular mechanisms of TGFbeta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
    Authors: Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W
    J. Immunol., 2008;181(4):2831-45.
    Species: Rat
    Sample Types: Urine
  185. Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
    Authors: Son A, Nakamura H, Okuyama H, Oka S, Yoshihara E, Liu W, Matsuo Y, Kondo N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
    Eur. J. Immunol., 2008;38(5):1358-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  186. The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response.
    Authors: Palma C, Iona E, Giannoni F, Pardini M, Brunori L, Fattorini L, Del Giudice G, Cassone A
    Vaccine, 2008;26(33):4237-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  187. Oridonin promotes CD4+/CD25+ Treg differentiation, modulates Th1/Th2 balance and induces HO-1 in rat splenic lymphocytes.
    Authors: Hu AP, Du JM, Li JY, Liu JW
    Inflamm. Res., 2008;57(4):163-70.
    Species: Rat
    Sample Types: Cell Culture Supernates
  188. Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes.
    Authors: Besin G, Gaudreau S, Menard M, Guindi C, Dupuis G, Amrani A
    Diabetes, 2008;57(8):2107-17.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  189. Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
    Authors: Yamazaki T, Nagata K, Kobayashi Y
    Cell. Immunol., 2008;251(2):124-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  190. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics.
    Authors: Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, Ouyang GF, Okada M, Balazs M, Adany R, Shibata T, Takami T
    J. Leukoc. Biol., 2008;83(5):1136-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  191. Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.
    Authors: Shweke N, Boulos N, Jouanneau C, Vandermeersch S, Melino G, Dussaule JC, Chatziantoniou C, Ronco P, Boffa JJ
    Am. J. Pathol., 2008;173(3):631-42.
    Species: Mouse
    Sample Types: Tissue Homogenates
  192. Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.
    Authors: Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS
    J. Clin. Invest., 2008;118(2):479-90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  193. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  194. Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
    Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
    J. Immunol., 2008;181(2):1491-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  195. Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells.
    Authors: Lau AW, Biester S, Cornall RJ, Forrester JV
    J. Immunol., 2008;180(6):3889-99.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  196. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension.
    Authors: Socha MJ, Manhiani M, Said N, Imig JD, Motamed K
    Am. J. Pathol., 2007;171(4):1104-12.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  197. A new murine model for bronchiolitis obliterans post-bone marrow transplant.
    Authors: Panoskaltsis-Mortari A, Tram KV, Price AP, Wendt CH, Blazar BR
    Am. J. Respir. Crit. Care Med., 2007;176(7):713-23.
    Species: Mouse
    Sample Types: Serum
  198. Characterization of in vitro antimurine thymocyte globulin-induced regulatory T cells that inhibit graft-versus-host disease in vivo.
    Authors: Ruzek MC, Waire JS, Hopkins D, Lacorcia G, Sullivan J, Roberts BL, Richards SM, Nahill SR, Williams JM, Scaria A, Dzuris J, Shankara S, Garman RD
    Blood, 2007;111(3):1726-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  199. Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
    Authors: Izumo T, Kondo M, Nagai A
    Life Sci., 2007;80(20):1882-6.
    Species: Mouse
    Sample Types: BALF
  200. Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
    Authors: Katiyar S, Jiao X, Wagner E, Lisanti MP, Pestell RG
    Mol. Cell. Biol., 2007;27(4):1356-69.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  201. Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo.
    Authors: Poncelet AJ, Vercruysse J, Saliez A, Gianello P
    Transplantation, 2007;83(6):783-90.
    Species: Porcine
    Sample Types: Cell Culture Supernates
  202. Liposomal retinoic acids modulate asthma manifestations in mice.
    Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M
    J. Nutr., 2007;137(12):2730-6.
    Species: Mouse
    Sample Types: BALF
  203. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
    Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
    J. Clin. Invest., 2007;117(12):3786-99.
    Species: Mouse
    Sample Types: BALF
  204. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
    Authors: Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR
    J. Immunol., 2007;178(2):851-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  205. Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model.
    Authors: Koyanagi T, Noguchi K, Ootani A, Inagaki K, Robbins RC, Mochly-Rosen D
    J. Mol. Cell. Cardiol., 2007;43(4):517-22.
    Species: Mouse
    Sample Types: Tissue Homogenates
  206. T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.
    Authors: Farini A, Meregalli M, Belicchi M, Battistelli M, Parolini D, D'Antona G, Gavina M, Ottoboni L, Constantin G, Bottinelli R, Torrente Y
    J. Pathol., 2007;213(2):229-38.
    Species: Mouse
    Sample Types: Tissue Homogenates
  207. Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
    Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
    Immunology, 2007;122(2):268-78.
    Species: Mouse
    Sample Types: BALF
  208. Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
    Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
    Blood, 2007;111(1):219-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  209. The role of the receptor for advanced glycation end-products in lung fibrosis.
    Authors: He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, Yamamoto H, Yamaya M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(6):L1427-36.
    Species: Mouse
    Sample Types: BALF
  210. Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model.
    Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T
    Biosci. Biotechnol. Biochem., 2006;70(8):2013-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  211. Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
    Authors: Greber B, Lehrach H, Adjaye J
    Stem Cells, 2006;25(2):455-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  212. Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma.
    Authors: Lee KS, Park SJ, Kim SR, Min KH, Jin SM, Lee HK, Lee YC
    J. Immunol., 2006;177(8):5248-57.
    Species: Mouse
    Sample Types: BALF
  213. Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
    Authors: Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK
    J. Cell. Biochem., 2006;97(5):1036-51.
    Species: Mouse
    Sample Types: Serum
  214. Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy.
    Authors: Li J, Campanale NV, Liang RJ, Deane JA, Bertram JF, Ricardo SD
    Am. J. Pathol., 2006;169(5):1527-40.
    Species: Mouse
    Sample Types: Tissue Homogenates
  215. Oxidative stress during peritoneal dialysis: implications in functional and structural changes in the membrane.
    Authors: Noh H, Kim JS, Han KH, Lee GT, Song JS, Chung SH, Jeon JS, Ha H, Lee HB
    Kidney Int., 2006;69(11):2022-8.
    Species: Rat
    Sample Types: Tissue Homogenates
  216. Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin.
    Authors: Garantziotis S, Brass DM, Savov J, Hollingsworth JW, McElvania-TeKippe E, Berman K, Walker JK, Schwartz DA
    Am. J. Respir. Cell Mol. Biol., 2006;35(6):662-7.
    Species: Mouse
    Sample Types: BALF
  217. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
    Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
    Arthritis Rheum., 2006;54(10):3182-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  218. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.
    Authors: Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R
    Arthritis Rheum., 2006;54(10):3363-71.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  219. Inhaled nitric oxide improves the survival of the paraquat-injured rats.
    Authors: Cho JH, Yang DK, Kim L, Ryu JS, Lee HL, Lim CM, Koh YS
    Vascul. Pharmacol., 2005;42(4):171-8.
    Species: Rat
    Sample Types: Serum
  220. Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
    Authors: Akool el-S, Doller A, Muller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W
    J. Biol. Chem., 2005;280(47):39403-16.
    Species: Rat
    Sample Types: Cell Culture Supernates
  221. Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
    Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
    Anticancer Res., 2005;25(1):299-303.
    Species: Mouse
    Sample Types: Tissue Secretion
  222. Measurement of bone morphogenetic proteins and other growth factors in demineralized bone matrix.
    Authors: Blum B, Moseley J, Miller L, Richelsoph K, Haggard W
    Orthopedics, 2004;27(1):161-5.
    Species: Human
    Sample Types: Tissue Homogenates
  223. Suppression of cytokine-inducible nitric oxide synthesis during intraperitoneal Meth A tumor growth.
    Authors: Kwon OD, Yim CY, Jeong KS, Park SC, Jung KY, McGregor JR, Bastian NR, Samlowski WE
    J. Vet. Med. Sci., 2004;66(5):357-65.
    Species: Mouse
    Sample Types: Ascites Fluid
  224. Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung.
    Authors: Bechara RI, Brown LA, Roman J, Joshi PC, Guidot DM
    Am. J. Respir. Crit. Care Med., 2004;170(2):188-94.
    Species: Rat
    Sample Types: Tissue Homogenates
  225. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004;199(10):1355-65.
    Species: Mouse
    Sample Types: Serum
  226. Marked airway eosinophilia prevents development of airway hyper-responsiveness during an allergic response in IL-5 transgenic mice.
    Authors: Kobayashi T, Iijima K, Kita H
    J. Immunol., 2003;170(11):5756-63.
    Species: Mouse
    Sample Types: BALF

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Reviews for Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit

Average Rating: 4.8 (Based on 6 Reviews)

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Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit
By Anonymous on 09/14/2019
Application: Sample Tested: Serum and Plasma

Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit
By Anonymous on 08/10/2019
Application: Sample Tested: C3H10T1/2 mouse embryonic fibroblast cell line

Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit
By Anonymous on 11/13/2018
Application: Sample Tested: culture medium

The kit is very sensitive to detect TGFbeta.


Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit
By Anonymous on 05/10/2017
Application: Sample Tested: RAW 264.7 mouse monocyte/macrophage cell line

Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit
By Anonymous on 12/14/2016
Application: Sample Tested: Mesenchymal stem cells

We use to monitor immunomodulatory effects of MSCs.


Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Kit
By Anonymous on 07/12/2016
Application: Sample Tested: Cell culture supernatant