Mouse Reg3D Antibody

Catalog #: MAB5678
1 Citation Datasheet / COA / SDS

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MAB5678
MAB5678-SP

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Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Reg3D Antibody Summary

Species Reactivity

Mouse

Specificity

This antibody detects mouse Reg3D in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Reg1A, 1B, recombinant mouse (rm) Reg1, 2, 3A, 3B, 3G, 4, or recombinant rat Reg3 is observed.

Source

Monoclonal Rat IgG_2A Clone # 518818

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant mouse Reg3D
Glu27-Gly175

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Immunohistochemistry

8-25 µg/mL

Perfusion fixed frozen sections of mouse pancreas

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Reg3D

Reg3D (regenerating islet-derived III delta), also called INGAPrP (islet neogenesis-associated protein-related protein) is an ~20 kDa member of the Reg family of secreted calcium-dependent C-type lectins. Reg proteins are involved in various biological functions, including acting as a survival/growth factors. Reg3D mRNA is expressed mainly in pancreatic islets and the digestive system. The mature 149 amino acid Reg3D shares ~50 - 70% amino acid sequence identity with other mammalian Reg3 proteins.

Long Name

Regenerating Islet-derived III delta

Entrez Gene IDs

30053 (Mouse)

Alternate Names

INGAPrP; islet neogenesis associated protein-related protein;Reg III delta;regenerating islet-derived 3 delta; Reg3D

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse Reg3D Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of beta-cell failure
Authors: J Son, W Du, M Esposito, K Shariati, H Ding, Y Kang, D Accili
Nature Communications, 2023-02-02;14(1):558.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC