Mouse TORC1 Antibody
Mouse TORC1 Antibody Summary
Accession # Q68ED7
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
TORC1, also known as CREB-regulated transcription coactivator 1 (crtc1), is a 67 kDa member of the TORC family. Mouse TORC1 is 630 amino acids (aa) in length. It contains multiple potential sites for phosphorylation and a serine-rich region from aa 295‑365. Mouse TORC1 is 97% and 90% aa identical to rat and human TORC1, respectively. TORC1 is highly expressed in specific regions of the brain including the cortex, hippocampus, and striatum. It functions as a transcription coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites.
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