Home / VE-Cadherin / Mouse VE-Cadherin Antibody

Mouse VE-Cadherin Antibody

Catalog #: AF1002
57 Citations 1 Review Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF1002
AF1002-SP
Detection of Mouse VE‑Cadherin by Western Blot.
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Product Details
Citations (57)
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Reviews (1)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse VE-Cadherin Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse VE-Cadherin in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross‑reactivity with recombinant human VE-Cadherin is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse VE-Cadherin
Asp46-Gln592
Accession # 2208309A
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.2 µg/mL
See below
Simple Western
10 µg/mL
See below
Immunohistochemistry
3-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Mouse VE‑Cadherin antibody by Western Blot. View Larger

Detection of Mouse VE‑Cadherin by Western Blot. Western blot shows lysates of mouse lung tissue and bEnd.3 mouse endothelioma cell line. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Mouse VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1002) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for VE‑Cadherin at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunohistochemistry VE-Cadherin antibody in Mouse Heart by Immunohistochemistry (IHC-P). View Larger

VE‑Cadherin in Mouse Heart. VE-Cadherin was detected in immersion fixed paraffin-embedded sections of mouse heart using Goat Anti-Mouse VE-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1002) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membranes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Simple Western Detection of Mouse VE-Cadherin antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Mouse VE‑Cadherin by Simple WesternTM. Simple Western lane view shows lysates of mouse lung tissue, loaded at 0.2 mg/mL. Specific bands were detected for VE‑Cadherin at approximately 118, 146 kDa (as indicated) using 10 µg/mL of Goat Anti-Mouse VE‑Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1002). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VE-Cadherin

The cadherin (Ca++-dependent adherence) superfamily is a large group of membrane-associated glycoproteins that engage in homotypic, calcium-dependent, cell-cell adhesion events. The superfamily can be divided into at least five major subfamilies based on molecule gene structure, and/or extracellular (EC) and intracellular domains (1-4). Subfamilies include classical/type I, atypical/type II, and desmosomal-related cadherins (1-3). VE-Cadherin (vascular endothelial cadherin; also cadherin-5 and CD144) is a 125 kDa atypical/type II subfamily cadherin. Its subfamily classification is based principally on its genomic structure, as its physical structure is notably divergent from other type II subfamily members (2, 3). Mouse VE-Cadherin is synthesized as a 784 amino acid (aa) type I transmembrane (TM) preproprotein that contains a 24 aa signal peptide, a 21 aa prosequence, a 554 aa extracellular region (ECR), a 21 aa TM segment, and a 164 aa cytoplasmic domain (5, 6). The ECR contains five Ca++-binding cadherin domains that are approximately 105 aa in length. Cadherin domains are comprised of two beta ‑sheets that are oriented like bread in a sandwich. Although complex, the N-terminal cadherin domain mediates trans interactions, while the internal domains contribute to cis multimerizations (7). Mouse VE-Cadherin ECR is 92%, 77%, and 73% aa identical to rat, human and porcine VE-Cadherin ECR, respectively. VE-Cadherin is involved in the maintenance of endothelial permeability. In this regard, VE-Cadherin does not initiate new blood vessel formation; it maintains it once formed. Thus, when VE‑Cadherin is downregulated, cells part and permeability increases (8). Notably, VEGF is known to promote vascular leakage, and apparently does so by inducing a beta ‑arrestin-dependent endocytosis of VE-Cadherin (9). Part of this effect may be mediated by VE‑Cadherin itself which is reported to increase the membrane half-life of VEGF R2 (10). VE-Cadherin acts homotypically at sites of zonula adherens. On each expressing cell, it is proposed that VE-Cadherin first forms a trimer, which then dimerizes with a trimeric counterpart in-trans. Alternatively, two cis-dimers could act in-trans to generate homotypic binding (11). In addition to cell adhesion, VE‑Cadherin also is reported to mediate TGF-beta receptor assembly. When clustered, VE‑Cadherin enhances T beta RII/T beta RI assembly into an active receptor complex on endothelial cells (12). VE-Cadherin is expressed on endothelial cells, trophoblast cells, endothelial progenitor cells and embryonic hematopoietic cells (5, 8, 13, 14).

References
  1. Patel, S.D. et al. (2007) Curr. Opin. Struct. Biol. 13:690.
  2. Vestweber, D. (2008) Arterioscler. Thromb. Vasc. Biol. 28:223.
  3. Vincent, P.A. et al. (2004) Am. J. Physiol. Cell. Physiol. 286:C987.
  4. Cavallaro, U. et al. (2006) Exp. Cell Res. 312:659.
  5. Breier, G. et al. (1996) Blood 87:630.
  6. Huber, P. et al. (1996) Genomics 32:21.
  7. Pokutta, S. and W.I. Weis (2007) Annu. Rev. Cell Dev. Biol. 23:237.
  8. Crosby, C.V. et al. (2005) Blood 105:2771.
  9. Gavard, J. and J.S. Gutkind (2006) Nat. Cell Biol. 8:1223.
  10. Calera, M.R. et al. (2004) Exp. Cell Res. 300:248.
  11. Hewat, E.A. et al. (2007) J. Mol. Biol. 365:744.
  12. Rudini, N. et al. (2008) EMBO J. 27:993.
  13. Kogata, N. et al. (2006) Circ. Res. 98:897.
  14. Ema, M. et al. (2006) Blood 108:4018.
Long Name
Vascular Endothelium Cadherin
Entrez Gene IDs
1003 (Human); 12562 (Mouse)
Alternate Names
7B4 antigen; 7B4; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); Cadherin-5; CD144 antigen; CD144; CDH5; endothelial-specific cadherin; FLJ17376; Vascular endothelial cadherin; VECadherin; VE-Cadherin

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Citations for Mouse VE-Cadherin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

57 Citations: Showing 1 - 10
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  1. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression
    Authors: R Hashimoto, J Takahashi, K Shirakura, R Funatsu, K Kosugi, S Deguchi, M Yamamoto, Y Tsunoda, M Morita, K Muraoka, M Tanaka, T Kanbara, S Tanaka, S Tamiya, N Tokunoh, A Kawai, M Ikawa, C Ono, K Tachibana, M Kondoh, M Obana, Y Matsuura, A Ohsumi, T Noda, T Yamamoto, Y Yoshioka, YS Torisawa, H Date, Y Fujio, M Nagao, K Takayama, Y Okada
    Science Advances, 2022;8(38):eabo6783.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  2. Identification and implication of tissue-enriched ligands in epithelial-endothelial crosstalk during pancreas development
    Authors: M Moulis, SVM Runser, L Glorieux, N Dauguet, C Vanderaa, L Gatto, D Tyteca, P Henriet, FM Spagnoli, D Iber, CE Pierreux
    Scientific Reports, 2022;12(1):12498.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  3. Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
    Authors: W Zhang, Z Xu, X Hao, T He, J Li, Y Shen, K Liu, Y Gao, J Liu, D Edwards, AM Muscarella, L Wu, L Yu, L Xu, X Chen, YH Wu, IL Bado, Y Ding, S Aguirre, H Wang, Z Gugala, RL Satcher, ST Wong, XH Zhang
    Cancer Discovery, 2022;0(0):.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  4. Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice
    Authors: N Tisch, C Mogler, A Stojanovic, R Luck, EA Korhonen, A Ellerkmann, H Adler, M Singhal, G Schermann, L Erkert, JV Patankar, A Karakatsan, AL Scherr, Y Fuchs, A Cerwenka, S Wirtz, BC Köhler, HG Augustin, C Becker, T Schmidt, C Ruiz de Al
    Embo Molecular Medicine, 2022;0(0):e14121.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. The amyloid peptide beta disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner
    Authors: A Tarafdar, N Wolska, C Krisp, H Schlüter, G Pula
    Redox Biology, 2022;52(0):102287.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  6. Low-flow intussusception and metastable VEGFR2 signaling launch angiogenesis in ischemic muscle
    Authors: JM Arpino, H Yin, EK Prescott, SCR Staples, Z Nong, F Li, J Chevalier, B Balint, C O'Neil, R Mortuza, S Milkovich, JJ Lee, D Lorusso, M Sandig, DW Hamilton, DW Holdsworth, TL Poepping, CG Ellis, JG Pickering
    Science Advances, 2021;7(48):eabg9509.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  7. Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin &alpha5
    Authors: M Richards, S Pal, E Sjöberg, P Martinsson, L Venkatrama, L Claesson-W
    Cell Reports, 2021;35(12):109268.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  8. Protease nexin-1 deficiency increases mouse hindlimb neovascularisation following ischemia and accelerates femoral artery perfusion
    Authors: S Selbonne, C Madjene, B Salmon, Y Boulaftali, MC Bouton, V Arocas
    Scientific Reports, 2021;11(1):13412.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. CD112 Regulates Angiogenesis and T Cell Entry into the Spleen
    Authors: E Russo, P Runge, NH Jahromi, H Naboth, A Landtwing, R Montecchi, N Leicht, MC Hunter, Y Takai, C Halin
    Cells, 2021;10(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  10. Force-induced changes of alpha-catenin conformation stabilize vascular junctions independent of vinculin
    Authors: CN Duong, R Brückner, M Schmitt, AF Nottebaum, L Braun, MM Zu Brickwe, U Ipe, H Vom Bruch, HR Schöler, G Trapani, B Trappmann, MP Ebrahimkut, S Huveneers, J Rooij, N Ishiyama, M Ikura, D Vestweber
    Journal of Cell Science, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  11. Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches
    Authors: M Mesnieres, AM Böhm, N Peredo, D Trompet, R Valle-Tenn, M Bajaj, N Corthout, E Nefyodova, R Cardoen, P Baatsen, S Munck, A Nagy, JJ Haigh, S Khurana, CM Verfaillie, C Maes
    Cell Reports, 2021;36(8):109618.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas
    Authors: S Heino, S Fang, M Lähde, J Högström, S Nassiri, A Campbell, D Flanagan, A Raven, M Hodder, N Nasreddin, HH Xue, M Delorenzi, S Leedham, TV Petrova, O Sansom, K Alitalo
    Science Advances, 2021;7(47):eabj0512.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1
    Authors: B Lee, H Shin, JE Oh, J Park, M Park, SC Yang, JH Jun, SH Hong, H Song, HJ Lim
    Autophagy, 2020;0(0):1-18.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  14. Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors
    Authors: Z Wang, F Wang, J Zhong, T Zhu, Y Zheng, T Zhao, Q Xie, F Ma, R Li, Q Tang, F Xu, X Tian, J Zhu
    Nat Commun, 2020;11(1):2163.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  15. Atypical cadherin Fat4 orchestrates lymphatic endothelial cell polarity in response to flow
    Authors: KL Betterman, DL Sutton, GA Secker, J Kazenwadel, A Oszmiana, L Lim, N Miura, L Sorokin, BM Hogan, ML Kahn, H McNeill, NL Harvey
    J. Clin. Invest., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  16. Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy
    Authors: JH Wu, YN Li, AQ Chen, CD Hong, CL Zhang, HL Wang, YF Zhou, PC Li, Y Wang, L Mao, YP Xia, QW He, HJ Jin, ZY Yue, B Hu
    EMBO Mol Med, 2020;12(2):e10154.
    Species: Mouse
    Sample Types: Protein
    Applications: Western Blot
  17. Simulating flow induced migration in vascular remodelling
    Authors: A Tabibian, S Ghaffari, DA Vargas, H Van Ooster, EAV Jones
    PLoS Comput. Biol., 2020;16(8):e1007874.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  18. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
    Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
    Exp. Mol. Med., 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  19. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
    Authors: SP Hong, MJ Yang, H Cho, I Park, H Bae, K Choe, SH Suh, RH Adams, K Alitalo, D Lim, GY Koh
    Nat Commun, 2020;11(1):4102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria
    Authors: TK Darling, PN Mimche, C Bray, B Umaru, LM Brady, C Stone, CE Eboumbou M, TE Lane, LS Ayong, TJ Lamb
    PLoS Pathog., 2020;16(1):e1008261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  21. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
    Authors: SP Hong, MJ Yang, H Cho, I Park, H Bae, K Choe, SH Suh, RH Adams, K Alitalo, D Lim, GY Koh
    Nat Commun, 2020;11(1):4102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. Simulating flow induced migration in vascular remodelling
    Authors: A Tabibian, S Ghaffari, DA Vargas, H Van Ooster, EAV Jones
    PLoS Comput. Biol., 2020;16(8):e1007874.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  23. Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions
    Authors: JR Krambs, G Abou Ezzi, JC Yao, DC Link
    PLoS ONE, 2020;15(5):e0233751.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  24. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking
    Authors: J Zhang, T Supakornde, JR Krambs, M Rao, G Abou-Ezzi, RY Ye, S Li, K Trinkaus, DC Link
    J. Clin. Invest., 2019;129(7):2920-2931.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  25. Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis
    Authors: G Chiaverina, L di Blasio, V Monica, M Accardo, M Palmiero, B Peracino, M Vara-Messl, A Puliafito, L Primo
    Cells, 2019;8(9):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  26. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration
    Authors: X Han, Y Wang, W Pu, X Huang, L Qiu, Y Li, W Yu, H Zhao, X Liu, L He, L Zhang, Y Ji, J Lu, KO Lui, B Zhou
    Stem Cell Reports, 2019;12(3):624-638.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  27. Rhodocetin-?? selectively breaks the endothelial barrier of the tumor vasculature in HT1080 fibrosarcoma and A431 epidermoid carcinoma tumor models.
    Authors: Stephan Niland, Dorde Komljenov, Jadranka Macas, Thilo Bracht, Tobias Bäuerle, Stefan Liebner, Johannes A Eble
    Oncotarget, 2018;0(0):1949-2553.
    Species: Mouse
    Sample Types:
    Applications: IHC
  28. Gelatinolytic activity of autocrine matrix metalloproteinase-9 leads to endothelial de-arrangement in Moyamoya disease
    Authors: KG Blecharz-L, V Prinz, M Burek, D Frey, T Schenkel, SM Krug, M Fromm, P Vajkoczy
    J. Cereb. Blood Flow Metab., 2018;0(0):271678X187684.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  29. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
    Authors: G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, G Jarugumill, J van Rijsse, G Saladino, F Comitani, A Zecchin, S Rocha, R Chen, H Huang, S Vandekeere, J Kalucka, C Lange, F Morales-Ro, B Cruys, L Treps, L Ramer, S Vinckier, K Brepoels, S Wyns, J Souffreau, L Schoonjans, WH Lamers, Y Wu, J Haustraete, J Hofkens, S Liekens, R Cubbon, B Ghesquière, M Dewerchin, FL Gervasio, X Li, JD van Buul, X Wu, P Carmeliet
    Nature, 2018;561(7721):63-69.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  30. The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation
    Authors: I Milo, R Blecher-Go, Z Barnett-It, R Bar-Ziv, O Tal, I Gurevich, T Feferman, I Drexler, I Amit, P Bousso, G Shakhar
    Eur. J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  31. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis
    Authors: L Guo, H Akahori, E Harari, SL Smith, R Polavarapu, V Karmali, F Otsuka, RL Gannon, RE Braumann, MH Dickinson, A Gupta, AL Jenkins, MJ Lipinski, J Kim, P Chhour, PS de Vries, H Jinnouchi, R Kutys, H Mori, MD Kutyna, S Torii, A Sakamoto, CU Choi, Q Cheng, ML Grove, MA Sawan, Y Zhang, Y Cao, FD Kolodgie, DP Cormode, DE Arking, E Boerwinkle, AC Morrison, J Erdmann, N Sotoodehni, R Virmani, AV Finn
    J. Clin. Invest., 2018;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  32. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
    Authors: J Cao, M Ehling, S März, J Seebach, K Tarbashevi, T Sixta, ME Pitulescu, AC Werner, B Flach, E Montanez, E Raz, RH Adams, H Schnittler
    Nat Commun, 2017;8(1):2210.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  33. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
    Authors: L Tian, A Goldstein, H Wang, H Ching Lo, I Sun Kim, T Welte, K Sheng, LE Dobrolecki, X Zhang, N Putluri, TL Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, WK Decker, C Zong, MT Lewis, XH Zhang
    Nature, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  34. Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?
    Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik
    Stem Cell Reports, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  35. Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation
    Authors: AJ Mead, WH Neo, N Barkas, S Matsuoka, A Giustacchi, R Facchini, S Thongjuea, L Jamieson, CAG Booth, N Fordham, C Di Genua, D Atkinson, O Chowdhury, E Repapi, N Gray, S Kharazi, SA Clark, T Bouriez, P Woll, T Suda, C Nerlov, SEW Jacobsen
    J. Exp. Med., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  36. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
    Nat Commun, 2016;7(0):12422.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  37. Targeting of Mesenchymal Stromal Cells by Cre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells
    Authors: Jingzhu Zhang
    J Bone Miner Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  38. Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.
    Authors: Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha S, Parkinson L, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang L, Williams S, Bleackley R, Eriksson J, Seidman M, McManus B, Granville D
    Am J Pathol, 2016;186(1):87-100.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: Western Blot
  39. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver
    JCI Insight, 2016;1(21):e87058.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  40. Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts.
    Authors: Zang G, Gustafsson K, Jamalpour M, Hong J, Genove G, Welsh M
    BMC Cancer, 2015;15(0):234.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  41. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases.
    Authors: Yin H, Frontini M, Arpino J, Nong Z, O'Neil C, Xu Y, Balint B, Ward A, Chakrabarti S, Ellis C, Gros R, Pickering J
    J Biol Chem, 2015;290(36):22127-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  42. Blood vessels pattern heparan sulfate gradients between their apical and basolateral aspects.
    Authors: Stoler-Barak, Liat, Moussion, Christin, Shezen, Elias, Hatzav, Miki, Sixt, Michael, Alon, Ronen
    PLoS ONE, 2014;9(1):e85699.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.
    Authors: Ding B, Cao Z, Lis R, Nolan D, Guo P, Simons M, Penfold M, Shido K, Rabbany S, Rafii S
    Nature, 2014;505(7481):97-102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  44. Neuroligin 1 induces blood vessel maturation by cooperating with the alpha6 integrin.
    Authors: Samarelli A, Riccitelli E, Bizzozero L, Silveira T, Seano G, Pergolizzi M, Vitagliano G, Cascone I, Carpentier G, Bottos A, Primo L, Bussolino F, Arese M
    J Biol Chem, 2014;289(28):19466-76.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  45. Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo.
    Authors: Bowles J, Secker G, Nguyen C, Kazenwadel J, Truong V, Frampton E, Curtis C, Skoczylas R, Davidson T, Miura N, Hong Y, Koopman P, Harvey N, Francois M
    Dev Biol, 2014;386(1):25-33.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  46. Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice.
    Authors: Lu, Zhi Hong, Kaliberov, Sergey, Sohn, Rebecca, Kaliberova, Lyudmila, Curiel, David T, Arbeit, Jeffrey
    PLoS ONE, 2013;8(12):e83933.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  47. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.
    Authors: Kohler, Erin E, Wary, Kishore, Li, Fei, Chatterjee, Ishita, Urao, Norifumi, Toth, Peter T, Ushio-Fukai, Masuko, Rehman, Jalees, Park, Changwon, Malik, Asrar B
    PLoS ONE, 2013;8(12):e85549.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  48. VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.
    Authors: Sun Z, Li X, Massena S, Kutschera S, Padhan N, Gualandi L, Sundvold-Gjerstad V, Gustafsson K, Choy WW, Zang G, Quach M, Jansson L, Phillipson M, Abid MR, Spurkland A, Claesson-Welsh L
    J. Exp. Med., 2012;209(7):1363-77.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  49. Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice.
    Authors: Marrotte EJ, Chen DD, Hakim JS
    J. Clin. Invest., 2010;120(12):4207-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  50. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
    Authors: Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S
    Cell Stem Cell, 2010;6(3):251-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  51. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
    Authors: Mazzone M, Dettori D, Leite de Oliveira R, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, Ruiz de Almodovar C, De Smet F, Vinckier S, Aragones J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P
    Cell, 2009;136(5):839-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  52. Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth.
    Authors: Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M
    Cancer Res., 2009;69(5):2141-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  53. Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays.
    Authors: Cordey M, Limacher M, Kobel S, Taylor V, Lutolf MP
    Stem Cells, 2008;26(10):2586-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  54. Genetic delivery of the murine equivalent of bevacizumab (avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice.
    Authors: Watanabe M, Boyer JL, Hackett NR, Qiu J, Crystal RG
    Hum. Gene Ther., 2008;19(3):300-10.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  55. Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors.
    Authors: Li X, Edholm D, Lanner F, Breier G, Farnebo F, Dimberg A, Claesson-Welsh L
    Stem Cells, 2007;25(12):2987-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  56. Effect of gestational nutrition on vascular integrity in the murine placenta.
    Authors: Rutland CS, Latunde-Dada AO, Thorpe A, Plant R, Langley-Evans S, Leach L
    Placenta, 2006;28(7):734-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.
    Authors: Liu Q, Yang R, Huang X, Zhang H, He L, Zhang L, Tian X, Nie Y, Hu S, Yan Y, Zhang L, Qiao Z, Wang Q, Lui K, Zhou B
    Cell Res, 0;26(1):119-30.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr

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Isotype Controls

Normal Goat IgG Control

AB-108-C
351 Citations
18 Reviews
1 Image
Ctrl

Reconstitution Buffers

Reconstitution Buffer 1 (PBS)

RB01
3 Reviews

Secondary Antibodies

Chicken Anti-Goat IgG Biotinylated Antibody

BAF019
WB

Donkey Anti-Goat IgG (H+L) PerCP-conjugated Antibody

F0124
Flow

Donkey Anti-Goat IgG Antibody

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Donkey Anti-Goat IgG Biotinylated Antibody

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Donkey Anti-Goat IgG NorthernLights™ NL637-conjugated Antibody

NL002
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Goat IgG (H+L) APC-conjugated Antibody

F0108
12 Citations
1 Image
Flow

Goat IgG (H+L) Fluorescein-conjugated Antibody

F0109
3 Citations
1 Image
Flow

Goat IgG (H+L) PE-conjugated Antibody

F0107
10 Citations
2 Reviews
1 Image
Flow

Goat IgG HRP-conjugated Antibody

HAF017
53 Citations
8 Reviews
1 Image
WB

Goat IgG HRP-conjugated Antibody

HAF109
47 Citations
3 Reviews
2 Images
WB,Simple Western

Goat IgG Horseradish Peroxidase-conjugated Antibody

HAF019
17 Citations
1 Image
WB

Goat IgG VisUCyte HRP Polymer

VC004
5 Citations
1 Image
IHC

Rabbit Anti-Goat IgG (H+L) Antibody, X Absorbed

R-401-C-ABS
WB,ELISA

Rabbit Anti-Goat IgG Biotinylated Antibody

BAF017
2 Citations
1 Review
WB

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Mouse VE-Cadherin Antibody
By Anonymous on 08/13/2021
Application: IHC Sample Tested: Skin tissue Species: Mouse
Immunohistochemistry Mouse VE-Cadherin Antibody AF1002