Mouse VEGF R3/Flt-4 Antibody

Catalog # Availability Size / Price Qty
AF743
AF743-SP
Detection of VEGF R3/Flt‑4 in bEnd.3 Mouse Cell Line by Flow Cytometry.
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Product Details
Citations (51)
FAQs
Supplemental Products
Reviews (2)

Mouse VEGF R3/Flt-4 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse VEGF R3/Flt-4 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) VEGF R3, 10% cross-reactivity with rhVEGF R2, and 5% cross-reactivity with rhVEGF R1.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse VEGF R3/Flt-4
Tyr25-Asp770
Accession # P35917
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse VEGF R3/Flt‑4 Fc Chimera (Catalog # 743-R3)
Flow Cytometry
0.25 µg/106 cells
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of VEGF R3/Flt‑4 in bEnd.3 Mouse Cell Line by Flow Cytometry. View Larger

Detection of VEGF R3/Flt‑4 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 cells, a mouse endothelioma cell line, was stained with Goat Anti-Mouse VEGF R3/Flt‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF743, filled histogram) or isotype control antibody (Catalog # AB-108-C, open histogram), followed by PE-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107).

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VEGF R3/Flt-4

VEGF R3 (Flt-4), together with VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1), belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of these receptors is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis.

In adults, VEGF R3 expression is restricted to the endothelial cells of the lymphatic vessels. Mouse VEGF R3 cDNA encodes a 1363 amino acid (aa) residue precursor protein with a 24 aa residue signal peptide. Mature VEGF R3 has a 751 aa residue extracellular domain, a 22 aa residue hydrophobic transmembrane domain and a 565 aa residue cytoplasmic domain. The polypeptide sequences of murine Flt-4 is 88% identical to the human homologue. VEGF R3 has been reported to serve as the receptors for VEGF-C and VEGF-D.

References
  1. Finnerty, H. et al. (1993) Oncogene 8:2293.
  2. Joukov, V. et al. (1996) EMBO J. 15:290.
  3. Achen, M. et al. (1998) Proc. Natl. Acad. Sci. USA 95:548.
Long Name
Vascular Endothelial Growth Factor Receptor 3
Entrez Gene IDs
2324 (Human); 14257 (Mouse)
Alternate Names
EC 2.7.10; EC 2.7.10.1; FLT4; Flt-4; fms-related tyrosine kinase 4; LMPH1A; PCLFLT41; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; Tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor 3; VEGF R3; VEGFR3; VEGFR-3; VEGFR3Fms-like tyrosine kinase 4

Product Datasheets

Citations for Mouse VEGF R3/Flt-4 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

51 Citations: Showing 1 - 10
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  1. Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread
    Authors: Q Ma, LC Dieterich, K Ikenberg, SB Bachmann, J Mangana, ST Proulx, VC Amann, MP Levesque, R Dummer, P Baluk, DM McDonald, M Detmar
    Sci Adv, 2018;4(8):eaat4758.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  2. HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development
    Authors: S Gauvrit, A Villasenor, B Strilic, P Kitchen, MM Collins, R Marín-Juez, S Guenther, HM Maischein, N Fukuda, MA Canham, JM Brickman, CW Bogue, PS Jayaraman, DYR Stainier
    Nat Commun, 2018;9(1):2704.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-F
  3. Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms
    Authors: Y Zhang, MH Ulvmar, L Stanczuk, I Martinez-C, M Frye, K Alitalo, T Mäkinen
    Nat Commun, 2018;9(1):1296.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  4. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program
    Authors: M Frye, A Taddei, C Dierkes, I Martinez-C, M Fielden, H Ortsäter, J Kazenwadel, DP Calado, P Ostergaard, M Salminen, L He, NL Harvey, F Kiefer, T Mäkinen
    Nat Commun, 2018;9(1):1511.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators
    Authors: CA Thomson, SA van de Pav, M Stakenborg, E Labeeuw, G Matteoli, AM Mowat, RJB Nibbs
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  6. FGF-dependent metabolic control of vascular development
    Authors: P Yu, K Wilhelm, A Dubrac, JK Tung, TC Alves, JS Fang, Y Xie, J Zhu, Z Chen, F De Smet, J Zhang, SW Jin, L Sun, H Sun, RG Kibbey, KK Hirschi, N Hay, P Carmeliet, TW Chittenden, A Eichmann, M Potente, M Simons
    Nature, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  7. Vitamin D inhibits lymphangiogenesis through VDR-dependent mechanisms
    Authors: S Yazdani, F Poosti, L Toro, J Wedel, R Mencke, K Mirkovi?, MH de Borst, JS Alexander, G Navis, H van Goor, J van den Bo, JL Hillebrand
    Sci Rep, 2017;7(0):44403.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  8. Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma
    Authors: J Kim, DY Park, H Bae, DY Park, D Kim, CK Lee, S Song, TY Chung, DH Lim, Y Kubota, YK Hong, Y He, HG Augustin, G Oliver, GY Koh
    J. Clin. Invest., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1
    Authors: SK Jha, K Rauniyar, T Karpanen, VM Leppänen, P Brouillard, M Vikkula, K Alitalo, M Jeltsch
    Sci Rep, 2017;7(1):4916.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  10. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis
    Authors: UH Langen, ME Pitulescu, JM Kim, R Enriquez-G, KK Sivaraj, AP Kusumbe, A Singh, J Di Russo, MG Bixel, B Zhou, L Sorokin, JM Vaquerizas, RH Adams
    Nat. Cell Biol, 2017;19(3):189-201.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  11. Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction
    Authors: F Tatin, E Renaud-Gab, AC Godet, F Hantelys, F Pujol, F Morfoisse, D Calise, F Viars, P Valet, B Masri, AC Prats, B Garmy-Susi
    JCI Insight, 2017;2(12):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis
    Authors: JY Jang, SY Choi, I Park, DY Park, K Choe, P Kim, YK Kim, BJ Lee, M Hirashima, Y Kubota, JW Park, SY Cheng, A Nagy, YJ Park, K Alitalo, M Shong, GY Koh
    EMBO Mol Med, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. Basophil-derived IL-6 regulates TH17 cell differentiation and CD4 T cell immunity
    Authors: CM Yuk, HJ Park, BI Kwon, SJ Lah, J Chang, JY Kim, KM Lee, SH Park, S Hong, SH Lee
    Sci Rep, 2017;7(0):41744.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  14. VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling
    Authors: K Heinolaine, S Karaman, G D'Amico, T Tammela, R Sormunen, L Eklund, K Alitalo, G Zarkada
    Circ. Res, 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: WB
  15. Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine
    Authors: D Olmeda, D Cerezo-Wal, E Riveiro-Fa, PC Pennacchi, M Contreras-, N Ibarz, M Cifdaloz, X Catena, TG Calvo, E Cañón, D Alonso-Cur, J Suarez, L Osterloh, O Graña, F Mulero, D Megías, M Cañamero, JL Martínez-T, C Mondal, J Di Martino, D Lora, I Martinez-C, JJ Bravo-Cord, J Muñoz, S Puig, P Ortiz-Rome, JL Rodriguez-, S Ortega, MS Soengas
    Nature, 2017;546(7660):676-680.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC paraffin embedded
  16. G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling
    Cell Rep, 2016;17(10):2532-2541.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Paraffin-Embedded
  17. Mechanotransduction activates canonical Wnt/?-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves
    Authors: Boksik Cha
    Genes Dev, 2016;30(12):1454-69.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen
  18. Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43
    Authors: Alexander M Simon
    Dev. Biol., 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  19. Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1
    Cell Rep, 2016;17(9):2299-2311.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules.
    Authors: Aspelund A, Antila S, Proulx S, Karlsen T, Karaman S, Detmar M, Wiig H, Alitalo K
    J Exp Med, 2015;212(7):991-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Not Specified
  21. Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain.
    Authors: Walchli T, Mateos J, Weinman O, Babic D, Regli L, Hoerstrup S, Gerhardt H, Schwab M, Vogel J
    Nat Protoc, 2015;10(1):53-74.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. EphB4 forward signalling regulates lymphatic valve development.
    Authors: Zhang, Gu, Brady, John, Liang, Wei-Chin, Wu, Yan, Henkemeyer, Mark, Yan, Minhong
    Nat Commun, 2015;6(0):6625.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Fresh
  23. Delayed Healing of Sickle Cell Ulcers Is due to Impaired Angiogenesis and CXCL12 Secretion in Skin Wounds.
    Authors: Nguyen V, Nassar D, Batteux F, Raymond K, Tharaux P, Aractingi S
    J Invest Dermatol, 2015;136(2):497-506.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Paraffin-embedded
  24. Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.
    Authors: Zhou Y, Williams J, Smallwood P, Nathans J
    PLoS ONE, 2015;10(12):e0143650.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Frozen
  25. Structural and functional features of central nervous system lymphatic vessels.
    Authors: Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, Derecki N, Castle D, Mandell J, Lee K, Harris T, Kipnis J
    Nature, 2015;523(7560):337-41.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Not Specified
  26. The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.
    Authors: Aspelund A, Tammela T, Antila S, Nurmi H, Leppanen V, Zarkada G, Stanczuk L, Francois M, Makinen T, Saharinen P, Immonen I, Alitalo K
    J Clin Invest, 2014;124(9):3975-86.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Fresh
  27. Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice.
    Authors: Huang Y, Caputo C, Noordmans G, Yazdani S, Monteiro L, van den Born J, van Goor H, Heeringa P, Korstanje R, Hillebrands J
    PLoS ONE, 2014;9(3):e91850.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen
  28. Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.
    Authors: Lindskog, Henrik, Kim, Yung Hae, Jelin, Eric B, Kong, Yupeng, Guevara-Gallardo, Salvador, Kim, Tyson N, Wang, Rong A
    Development, 2014;141(5):1120-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  29. Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity.
    Authors: Park D, Lee J, Park I, Choi D, Lee S, Song S, Hwang Y, Hong K, Nakaoka Y, Makinen T, Kim P, Alitalo K, Hong Y, Koh G
    J Clin Invest, 2014;124(9):3960-74.
  30. Preferential lymphatic growth in bronchus-associated lymphoid tissue in sustained lung inflammation.
    Authors: Baluk P, Adams A, Phillips K, Feng J, Hong Y, Brown M, McDonald D
    Am J Pathol, 2014;184(5):1577-92.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  31. Schlemm's canal is a unique vessel with a combination of blood vascular and lymphatic phenotypes that forms by a novel developmental process.
    Authors: Kizhatil, Krishnak, Ryan, Margaret, Marchant, Jeffrey, Henrich, Stephen, John, Simon W
    PLoS Biol, 2014;12(7):e1001912.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  32. Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.
    Authors: Ramasamy S, Kusumbe A, Wang L, Adams R
    Nature, 2014;507(7492):376-80.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen
  33. Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions.
    Authors: Zheng W, Nurmi H, Appak S, Sabine A, Bovay E, Korhonen E, Orsenigo F, Lohela M, D'Amico G, Holopainen T, Leow C, Dejana E, Petrova T, Augustin H, Alitalo K
    Genes Dev, 2014;28(14):1592-603.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen
  34. Fusing VE-cadherin to alpha-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation.
    Authors: Dartsch N, Schulte D, Hagerling R, Kiefer F, Vestweber D
    Mol Cell Biol, 2014;34(9):1634-48.
    Species: Mouse
    Sample Types: Embryo
    Applications: IHC Paraffin-embedded
  35. A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.
    Authors: Hagerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams R, Alitalo K, Andresen V, Schulte-Merker S, Kiefer F
    EMBO J, 2013;32(5):629-44.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC OCT-embedded
  36. Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma.
    Authors: Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, Ruan J, Xia L
    Cancer Res, 2013;73(24):7254-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: WB
  37. Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis.
    Authors: Yazdani S, Poosti F, Kramer A, Mirkovic K, Kwakernaak A, Hovingh M, Slagman M, Sjollema K, de Borst M, Navis G, van Goor H, van den Born J
    PLoS ONE, 2012;7(11):e50209.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  38. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.
    Authors: Benedito R, Rocha S, Woeste M, Zamykal M, Radtke F, Casanovas O, Duarte A, Pytowski B, Adams R
    Nature, 2012;484(7392):110-4.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ELISA Development
  39. Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli.
    Authors: Betterman K, Paquet-Fifield S, Asselin-Labat M, Visvader J, Butler L, Stacker S, Achen M, Harvey N
    Am J Pathol, 2012;181(6):2225-38.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen
  40. Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3.
    Authors: Xu Y, Yuan L, Mak J, Pardanaud L, Caunt M, Kasman I, Larrivee B, Del Toro R, Suchting S, Medvinsky A, Silva J, Yang J, Thomas JL, Koch AW, Alitalo K, Eichmann A, Bagri A
    J. Cell Biol., 2010;188(1):115-30.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Fresh
  41. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis.
    Authors: Wang Y, Nakayama M, Pitulescu ME, Schmidt TS, Bochenek ML, Sakakibara A, Adams S, Davy A, Deutsch U, Luthi U, Barberis A, Benjamin LE, Makinen T, Nobes CD, Adams RH
    Nature, 2010;465(7297):483-6.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: IP
  42. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.
    Authors: Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY
    J. Clin. Invest., 2010;120(5):1694-707.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Paraffin-embedded
  43. Vascular endothelial growth factor-C induces lymphangitic carcinomatosis, an extremely aggressive form of lung metastases.
    Authors: Das S, Ladell DS, Podgrabinska S
    Cancer Res., 2010;70(5):1814-24.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  44. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.
    Authors: Tammela T, Zarkada G, Wallgard E, Murtomaki A, Suchting S, Wirzenius M, Waltari M, Hellstrom M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Yla-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K
    Nature, 2008;454(7204):656-60.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Fresh
  45. Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues.
    Authors: Lohela M, Helotera H, Haiko P, Dumont DJ, Alitalo K
    Am. J. Pathol., 2008;173(6):1891-901.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  46. Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.
    Authors: Wirzenius M, Tammela T, Uutela M, He Y, Odorisio T, Zambruno G, Nagy JA, Dvorak HF, Yla-Herttuala S, Shibuya M, Alitalo K
    J. Exp. Med., 2007;204(6):1431-40.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  47. Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth.
    Authors: Laakkonen P, Waltari M, Holopainen T, Takahashi T, Pytowski B, Steiner P, Hicklin D, Persaud K, Tonra JR, Witte L, Alitalo K
    Cancer Res., 2007;67(2):593-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  48. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain.
    Authors: Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL
    Nat. Neurosci., 2006;9(3):340-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen
  49. Visualization of IL-12/23p40 in vivo reveals immunostimulatory dendritic cell migrants that promote Th1 differentiation.
    Authors: Reinhardt RL, Hong S, Kang SJ, Wang ZE, Locksley RM
    J. Immunol., 2006;177(3):1618-27.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  50. Desmoplakin and Plakoglobin--specific markers of lymphatic vessels in the skin?
    Authors: Fedele C, Berens D, Rautenfeld V, Pabst R
    Anat Histol Embryol, 2004;33(3):168-71.
    Species: Equine
    Sample Types: Whole Tissue
    Applications: IHC
  51. B lymphocyte-specific c-Myc expression stimulates early and functional expansion of the vasculature and lymphatics during lymphomagenesis.
    Authors: Ruddell A, Mezquita P, Brandvold KA, Farr A, Iritani BM
    Am. J. Pathol., 2003;163(6):2233-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC

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Mouse VEGF R3/Flt-4 Antibody
By Anonymous on 08/10/2017
Application: ICC/IF Sample Tested: Adrenal gland tissue Species: Mouse

Mouse VEGF R3/Flt-4 Antibody
By Anonymous on 10/04/2016
Application: ICC/IF Sample Tested: Mesentery whole mount Species: Mouse

Whole mount immunofluorescence of mouse mesenteric lymphatics. Mesentery was dissected from a P5 neonate, fixed in 2% PFA and stained using AF743 at a 1:200 dilution.