Home / TGF-beta 1 / Recombinant Human TGF-beta 1 Protein

Recombinant Human TGF-beta 1 Protein

240-B 516 Citations 25 Reviews Datasheet / COA / SDS
Newer Version Available: 7754-BH-005
A New TGF-beta 1 is Available! The new protein is Hek293 expressed!
Formulations:
Catalog # Availability Size / Price Qty
240-B-002
240-B-010
Recombinant Human TGF-beta 1 Protein Bioactivity
3 Images
Product Details
Citations (516)
FAQs
Supplemental Products
Reviews (25)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human TGF-beta 1 Protein Summary

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389. The ED50 for this effect is 0.04-0.2 ng/mL.
The specific activity of Recombinant Human TGF-beta 1 is approximately 2.5 x 104 U/μg, which is calibrated against human TGF‑ beta 1 Standard (NIBSC code: 89/514).
Source
Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein
Ala279-Ser390
Accession #
P01137
N-terminal Sequence
Analysis
Ala279
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
12.8 kDa (monomer)
SDS-PAGE
12 kDa, reducing conditions
24 kDa, non-reducing conditions

Product Datasheets

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

240-B

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Purified recombinant human TGF-beta 1 is an extremely hydrophobic protein that adheres strongly to surfaces. To ensure recovery, reconstitute at 20 μg/mL in sterile 4 mM HCl containing 1 mg/mL human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

240-B/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute 2 µg vials at 20 µg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin. Reconstitute 10 µg or larger vials at 100 µg/mL in sterile 4 mM HCl.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Recombinant Human TGF-beta 1 Protein Bioactivity View Larger

Recombinant Human TGF-beta 1 (Catalog # 240-B) inhibits Recombinant Mouse IL‑4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line. The ED50 for this effect is 0.04-0.2 ng/mL.

SDS-PAGE Recombinant Human TGF-beta 1 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Human TGF-beta 1 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 12 kDa and 24 kDa, respectively.

Bioactivity Recombinant Human TGF-beta 1 Protein Bioactivity View Larger

Epithelial to Mesenchymal Transition (EMT) was induced in the A549 human lung carcinoma cell line with cell culture media supplemented with Recombinant Human (rh) TGF-beta 1 (Catalog # 240-B). Control cells were cultured without rhTGF-beta 1. EMT induction was confirmed at 48 h by flow cytometric staining for E-Cadherin (filled; Catalog # FAB18381P), an epithelial cell marker, or an isotype control (Catalog # IC0041P). TGF-beta 1 decreased the expression of E-Cadherin.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TGF-beta 1

TGF-beta 1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure (1‑7). TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition (1‑4). Each TGF-beta isoform has some non‑redundant functions; for TGF-beta 1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation, and die of overwhelming inflammation (2). Human TGF‑ beta 1 cDNA encodes a 390 amino acid (aa) precursor that contains a 29 aa signal peptide and a 361 aa proprotein (8). A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1 (8, 9). Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex (8‑10). Covalent linkage of LAP to one of three latent TGF‑ beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix (9, 10). TGF‑ beta is activated from latency by pathways that include actions of the protease plasmin, matrix metalloproteases, thrombospondin 1 and a subset of integrins (10). Mature human TGF‑ beta 1 shares 100% aa identity with pig, dog and cow TGF‑ beta 1, and 99% aa identity with mouse, rat and horse TGF‑ beta 1. It demonstrates cross‑species activity (1). TGF‑ beta 1 signaling begins with high‑affinity binding to a type II ser/thr kinase receptor termed TGF‑ beta RII. This receptor then phosphorylates and activates a second ser/thr kinase receptor, TGF‑ beta RI (also called activin receptor‑like kinase (ALK) ‑5), or alternatively, ALK‑1. This complex phosphorylates and activates Smad proteins that regulate transcription (3, 11, 12). Contributions of the accessory receptors betaglycan (also known as TGF‑ beta  RIII) and endoglin, or use of Smad‑independent signaling pathways, allow for disparate actions observed in response to TGF‑ beta in different contexts (11).

References
  1. Derynck, R. and K. Miyazono (2008) Cold Spring Harbor Laboratory Press, 29.
  2. Dunker, N. and K. Krieglstein (2000) Eur. J. Biochem. 267:6982.
  3. Wahl, S.M. (2006) Immunol. Rev. 213:213.
  4. Chang, H. et al. (2002) Endocr. Rev. 23:787.
  5. Lin, J.S. et al. (2006) Reproduction 132:179.
  6. Hinck, A.P. et al. (1996) Biochemistry 35:8517.
  7. Mittl, P.R.E. et al. (1996) Protein Sci. 5:1261.
  8. Derynck, R. et al. (1985) Nature 316:701.
  9. Miyazono, K. et al. (1988) J. Biol. Chem. 263:6407.
  10. Oklu, R. and R. Hesketh (2000) Biochem. J. 352:601.
  11. de Caestecker, M. et al. (2004) Cytokine Growth Factor Rev. 15:1.
  12. Zuniga, J.E. et al. (2005) J. Mol. Biol. 354:1052.
Long Name
Transforming Growth Factor beta 1
Entrez Gene IDs
7040 (Human); 21803 (Mouse); 59086 (Rat); 397078 (Porcine); 100033900 (Equine)
Alternate Names
CEDLAP; DPD1; latency-associated peptide; TGFB; TGFB1; TGF-beta 1 protein; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1; transforming growth factor beta-1; transforming growth factor, beta 1

Citations for Recombinant Human TGF-beta 1 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

516 Citations: Showing 1 - 10
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  1. PyMT-1099, a versatile murine cell model for EMT in breast cancer
    Authors: M Saxena, RKR Kalathur, M Neutzner, G Christofor
    Sci Rep, 2018;8(1):12123.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Comparing Effects of Transforming Growth Factor ?1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels
    Authors: S Lively, D Lam, R Wong, LC Schlichter
    Front Cell Neurosci, 2018;12(0):115.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  3. A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials
    Authors: H Fraser, N Safinia, N Grageda, S Thirkell, K Lowe, LJ Fry, C Scottá, A Hope, C Fisher, R Hilton, D Game, P Harden, A Bushell, K Wood, RI Lechler, G Lombardi
    Mol Ther Methods Clin Dev, 2018;8(0):198-209.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. The prion protein is embedded in a molecular environment that modulates transforming growth factor ? and integrin signaling
    Authors: F Ghodrati, M Mehrabian, D Williams, O Halgas, MEC Bourkas, JC Watts, EF Pai, G Schmitt-Ul
    Sci Rep, 2018;8(1):8654.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke
    Authors: R Zhang, Y Wu, F Xie, Y Zhong, Y Wang, M Xu, J Feng, J Charish, PP Monnier, X Qin
    Cell Death Differ., 2018;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Frizzled-8 integrates Wnt-11 and transforming growth factor-? signaling in prostate cancer
    Authors: V Murillo-Ga, I Gorroño-Et, M Åkerfelt, MC Puustinen, L Sistonen, M Nees, J Carton, J Waxman, RM Kypta
    Nat Commun, 2018;9(1):1747.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Role of integrin alpha8 in murine model of lung fibrosis
    Authors: CF Hung, CL Wilson, YH Chow, LM Schnapp
    PLoS ONE, 2018;13(5):e0197937.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Curcumin inhibits TGF-?1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts
    Authors: JT Chen, CY Wang, MH Chen
    J. Formos. Med. Assoc., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Actin cytoskeleton assembly regulates collagen production via TGF-? type II receptor in human skin fibroblasts
    Authors: Z Qin, GJ Fisher, JJ Voorhees, T Quan
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Genetic and developmental origins of a unique foraging adaptation in a Lake Malawi cichlid genus
    Authors: MR Conith, Y Hu, AJ Conith, MA Maginnis, JF Webb, RC Albertson
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Fish
    Sample Types: In Vivo
    Applications: In Vivo
  11. TNFRSF19 inhibits TGF? signaling through interaction with TGF? receptor type I to promote tumorigenesis
    Authors: C Deng, YX Lin, XK Qi, GP He, Y Zhang, HJ Zhang, M Xu, QS Feng, JX Bei, YX Zeng, L Feng
    Cancer Res., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction
    Authors: G Zhou, H Jiang, Z Yin, Y Liu, Q Zhang, C Zhang, B Pan, J Zhou, X Zhou, H Sun, D Li, A He, Z Zhang, W Zhang, W Liu, Y Cao
    EBioMedicine, 2018;28(0):287-302.
    Species: Human
    Sample Types: Complex Sample Type
    Applications: Bioassay
  13. Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway
    Authors: CB Cummins, X Wang, O Nunez Lope, G Graham, HY Tie, J Zhou, RS Radhakrish
    Int J Mol Sci, 2018;19(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28
    Authors: Y Jiang, Y Liu, H Lu, SC Sun, W Jin, X Wang, C Dong
    Nat Commun, 2018;9(1):1424.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1
    Authors: Z Al Shareef, H Kardooni, V Murillo-Ga, G Domenici, E Stylianaki, JH Steel, M Rabano, I Gorroño-Et, I Zabalza, M dM Vivanco, J Waxman, RM Kypta
    Oncogene, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Isolation and characterization of mesenchymal stem cells from human fetus heart
    Authors: VNS Garikipati, SP Singh, Y Mohanram, AK Gupta, D Kapoor, S Nityanand
    PLoS ONE, 2018;13(2):e0192244.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis
    Authors: L Knüppel, K Heinzelman, M Lindner, R Hatz, J Behr, O Eickelberg, CA Staab-Weij
    Respir. Res., 2018;19(1):67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation
    Authors: S Patalano, J Rodríguez-, C Colaneri, J Cotellessa, D Almanza, A Zhilin-Rot, T Riley, J Macoska
    Sci Rep, 2018;8(1):3499.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. TGF-?1 promotes cell barrier function upon maturation of corneal endothelial cells
    Authors: V Beaulieu L, O Roy, K Santerre, S Proulx
    Sci Rep, 2018;8(1):4438.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. TGF? and IGF1R signaling activate protein kinase A through differential regulation of ezrin phosphorylation in colon cancer�cells
    Authors: PD Leiphrakpa, MG Brattain, JD Black, JJ Wang
    J. Biol. Chem., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model
    Authors: H Sugiura, A Matsushita, M Futaya, A Teraoka, KI Akiyama, N Usui, N Nagano, K Nitta, K Tsuchiya
    PLoS ONE, 2018;13(3):e0191706.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. TGF-? induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
    Authors: S Ottaviani, J Stebbing, AE Frampton, S Zagorac, J Krell, A de Giorgio, SM Trabulo, VTM Nguyen, L Magnani, H Feng, E Giovannett, N Funel, TM Gress, LR Jiao, Y Lombardo, NR Lemoine, C Heeschen, L Castellano
    Nat Commun, 2018;9(1):1845.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. MicroRNA-663 induces immune dysregulation by inhibiting TGF-?1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus
    Authors: L Geng, X Tang, K Zhou, D Wang, S Wang, G Yao, W Chen, X Gao, W Chen, S Shi, N Shen, X Feng, L Sun
    Cell. Mol. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-?1 signaling
    Authors: YH Chung, YH Huang, TH Chu, CL Chen, PR Lin, SC Huang, DC Wu, CC Huang, TH Hu, YH Kao, MH Tai
    Lab. Invest., 2018;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Impaired TGF-? signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22
    Authors: R Rekik, M Smiti Khan, T Larbi, I Zamali, A Beldi-Ferc, O Kammoun, S Marzouki, S Hamzaoui, S Mrad, MR Barbouche, MH Houman, M Ben Ahmed
    Cytokine, 2018;108(0):182-189.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase
    Authors: M Imamura, JS Moon, KP Chung, K Nakahira, T Muthukumar, R Shingarev, SW Ryter, AM Choi, ME Choi
    JCI Insight, 2018;3(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Canonical TGF-? Signaling Pathway Represses Human NK Cell Metabolism
    Authors: V Zaiatz-Bit, DK Finlay, CM Gardiner
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy
    Authors: S Deshpande, M Abdollahi, M Wang, L Lanting, M Kato, R Natarajan
    Sci Rep, 2018;8(1):6954.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. MicroRNA-21 in cancer-associated fibroblasts supports�lung adenocarcinoma progression
    Authors: A Kunita, S Morita, TU Irisa, A Goto, T Niki, D Takai, J Nakajima, M Fukayama
    Sci Rep, 2018;8(1):8838.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a
    Authors: S Tiwary, JE Morales, SC Kwiatkowsk, FF Lang, G Rao, JH McCarty
    Sci Rep, 2018;8(1):8267.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling
    Authors: J Wang, A Faiz, Q Ge, CJ Vermeulen, J Van der Ve, KJ Snibson, R van de Vel, S Sawant, D Xenaki, B Oliver, W Timens, N Ten Hacken, M van den Be, A James, JG Elliot, L Dong, JK Burgess, AW Ashton
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. CD8+ T cells with high TGF??1 expression cause lymph node fibrosis following HIV infection
    Authors: L Huang, J Deng, W Xu, H Wang, L Shi, F Wu, D Wu, W Nei, M Zhao, P Mao, X Zhou
    Mol Med Rep, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
    Authors: S Nowsheen, K Aziz, A Aziz, M Deng, B Qin, K Luo, KB Jeganathan, H Zhang, T Liu, J Yu, Y Deng, J Yuan, W Ding, JM van Deurse, Z Lou
    Nat. Cell Biol., 2018;20(4):455-464.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Chloroquine-treated dendritic cells require STAT1 signaling for their tolerogenic activity
    Authors: R Thome, AP Bonfanti, J Rasouli, ER Mari, GX Zhang, A Rostami, L Verinaud
    Eur. J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-?-dependent and -independent mechanisms
    Authors: J Nishida, K Miyazono, S Ehata
    Oncogene, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture
    Authors: MM Pleumeeker, L Nimeskern, JLM Koevoet, M Karperien, KS Stok, GJVM van Osch
    PLoS ONE, 2018;13(2):e0190744.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. miR-200b ameliorates myofibroblast transdifferentiation in precancerous oral submucous fibrosis through targeting ZEB2
    Authors: YW Liao, CC Yu, PL Hsieh, YC Chang
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy
    Authors: M Desancé, R Contentin, L Bertoni, T Gomez-Ledu, T Branly, S Jacquet, JM Betsch, A Batho, F Legendre, F Audigié, P Galéra, M Demoor
    Int J Mol Sci, 2018;19(2):.
    Species: Equine
    Sample Types: Whole Cells
    Applications: Bioassay
  39. TGF?1-induced Amelotin gene expression is downregulated by Bax expression in mouse gingival epithelial cells
    Authors: Y Nakayama, S Matsui, K Noda, M Yamazaki, Y Iwai, B Ganss, Y Ogata
    J Oral Sci, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
    Authors: A Schmidt, F Marabita, NA Kiani, CC Gross, HJ Johansson, S Éliás, S Rautio, M Eriksson, SJ Fernandes, G Silberberg, U Ullah, U Bhatia, H Lähdesmäki, J Lehtiö, D Gomez-Cabr, H Wiendl, R Lahesmaa, J Tegnér
    BMC Biol., 2018;16(1):47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/?-Catenin pathway
    Authors: L Jia, Y Tian, Y Chen, G Zhang
    Onco Targets Ther, 2018;11(0):313-321.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells
    Authors: X Hu, H Kan, A Boye, Y Jiang, C Wu, Y Yang
    Oncol Lett, 2018;15(4):4867-4872.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Essential role of connective tissue growth factor (CTGF) in transforming growth factor-?1 (TGF-?1)-induced myofibroblast transdifferentiation from Graves' orbital fibroblasts
    Authors: CC Tsai, SB Wu, HC Kau, YH Wei
    Sci Rep, 2018;8(1):7276.
    Applications: ELISA Standard
  44. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway
    Authors: F Zhang, G Liu, D Li, C Wei, J Hao
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases
    Authors: N Zila, A Bileck, B Muqaku, L Janker, OM Eichhoff, PF Cheng, R Dummer, MP Levesque, C Gerner, V Paulitschk
    Clin Proteomics, 2018;15(0):13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Expression ratio of the TGF?-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response
    Authors: D Dvornikov, MA Schneider, S Ohse, M Szczygie?, I Titkova, M Rosenblatt, T Muley, A Warth, FJ Herth, H Dienemann, M Thomas, J Timmer, M Schilling, H Busch, M Boerries, M Meister, U Klingmülle
    Sci Rep, 2018;8(1):9517.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Hydrogen sulfide promotes immunomodulation of gingiva-derived mesenchymal stem cells via the Fas/FasL coupling pathway
    Authors: R Yang, T Yu, D Liu, S Shi, Y Zhou
    Stem Cell Res Ther, 2018;9(1):62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Injectable cartilaginous template transformed BMSCs into vascularized bone
    Authors: X Feng, Z Li, J Wei, Z Feng, W Wu, Y Zhao
    Sci Rep, 2018;8(1):8244.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype
    Authors: F Wang, V Zachar, CP Pennisi, T Fink, Y Maeda, J Emmersen
    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium
    Authors: K Schlereth, D Weichenhan, T Bauer, T Heumann, E Giannakour, D Lipka, S Jaeger, M Schlesner, P Aloy, R Eils, C Plass, HG Augustin
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Overexpression of LncRNA AC067945.2 Down-Regulates Collagen Expression in Skin Fibroblasts and Possibly Correlates with the VEGF and Wnt Signalling Pathways
    Authors: L Chen, J Li, Q Li, X Li, Y Gao, X Hua, B Zhou, J Li
    Cell. Physiol. Biochem., 2018;45(2):761-771.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis
    Authors: LR Penke, JM Speth, VL Dommeti, ES White, IL Bergin, M Peters-Gol
    J. Clin. Invest., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling
    Authors: M Sato-Matsu, T Matsubara, A Daikoku, Y Okina, L Longato, K Rombouts, LTT Thuy, J Adachi, T Tomonaga, K Ikeda, K Yoshizato, M Pinzani, N Kawada
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells
    Authors: Y Tachida, N Izumi, T Sakurai, H Kobayashi
    Biol Open, 2017;6(3):370-380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer
    Authors: A Rynne-Vida, CL Au-Yeung, JA Jiménez-He, ML Pérez-Loza, L Cremades-J, C Bárcena, I Cristóbal-, C Fernández-, TL Yeung, SC Mok, P Sandoval, M López-Cabr
    J. Pathol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Cytidine monophosphate kinase is inhibited by the TGF-? signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer
    Authors: D Zhou, L Zhang, W Sun, W Guan, Q Lin, W Ren, J Zhang, G Xu
    Cell. Signal., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis
    Authors: H Kamata, Y Tsukasaki, T Sakai, R Ikebe, J Wang, A Jeffers, J Boren, S Owens, T Suzuki, M Higashihar, S Idell, TA Tucker, M Ikebe
    Sci Rep, 2017;7(1):4556.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma
    Authors: H Kusumoto, Y Shintani, R Kanzaki, T Kawamura, S Funaki, M Minami, I Nagatomo, E Morii, M Okumura
    Cancer Sci., 2017;108(3):528-535.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract
    Authors: BA Boswell, A Korol, JA West-Mays, LS Musil
    Mol. Biol. Cell, 2017;0(0):.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor ? Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice
    Authors: KH Bae, JB Seo, YA Jung, HY Seo, SH Kang, HJ Jeon, JM Lee, S Lee, JG Kim, IK Lee, GS Jung, KG Park
    Endocrinol Metab (Seoul), 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Tubastatin ameliorates pulmonary fibrosis by targeting the TGF?-PI3K-Akt pathway
    Authors: S Saito, Y Zhuang, B Shan, S Danchuk, F Luo, M Korfei, A Guenther, JA Lasky
    PLoS ONE, 2017;12(10):e0186615.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Supraphysiological levels of GDF11 induce striated muscle atrophy
    Authors: DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney
    EMBO Mol Med, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells
    Authors: G Mondanelli, R Bianchi, MT Pallotta, C Orabona, E Albini, A Iacono, ML Belladonna, C Vacca, F Fallarino, A Macchiarul, S Ugel, V Bronte, F Gevi, L Zolla, A Verhaar, M Peppelenbo, EM Mazza, S Bicciato, Y Laouar, L Santambrog, P Puccetti, C Volpi, U Grohmann
    Immunity, 2017;46(2):233-244.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells
    Authors: J Geng, S Yu, H Zhao, X Sun, X Li, P Wang, X Xiong, L Hong, C Xie, J Gao, Y Shi, J Peng, RL Johnson, N Xiao, L Lu, J Han, D Zhou, L Chen
    Nat. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
    Authors: MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat
    Proc. Natl. Acad. Sci. U.S.A, 2017;114(4):E524-E533.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance
    Authors: KA Whelan, PM Chandramou, K Tanaka, M Natsuizaka, M Guha, S Srinivasan, DS Darling, Y Kita, S Natsugoe, JD Winkler, AJ Klein-Szan, RK Amaravadi, NG Avadhani, AK Rustgi, H Nakagawa
    Oncogene, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. HR+HER2- breast cancers with growth factor receptor-mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells
    Authors: K Desai, R Aiyappa, JS Prabhu, MG Nair, PV Lawrence, A Korlimarla, A Ce, A Alexander, RS Kaluve, S Manjunath, M Correa, BS Srinath, S Patil, A Kalamdani, M Prasad, TS Sridhar
    Tumour Biol, 2017;39(3):1010428317695.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Dual roles of parathyroid hormone-related protein in TGF-?1 signaling and fibronectin upregulation in mesangial cells
    Authors: SZ Wu, SJ Yang, HM Chen, FF Peng, H Yu, JC Kreprinsky, BF Zhang
    Biosci. Rep., 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/?-catenin signaling
    Authors: Y Zhang
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
    Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. TGF-? signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes
    Authors: S Khakipoor, C Ophoven, M Schrödl-Hä, M Feuerstein, B Heimrich, JW Deitmer, E Roussa
    Glia, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Regulation of epithelial-mesenchymal transition and metastasis by TGF-?, P-bodies, and autophagy
    Authors: SD Hardy, A Shinde, WH Wang, MK Wendt, RL Geahlen
    Oncotarget, 2017;8(61):103302-103314.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes
    Authors: JC Cheng, CP Tseng, MH Liao, CY Peng, JS Yu, PH Chuang, JT Huang, JJW Chen
    Sci Rep, 2017;7(1):4448.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming
    Authors: T Ruetz, U Pfisterer, B Di Stefano, J Ashmore, M Beniazza, TV Tian, DF Kaemena, L Tosti, W Tan, JR Manning, E Chantzoura, DR Ottosson, S Collombet, A Johnsson, E Cohen, K Yusa, S Linnarsson, T Graf, M Parmar, K Kaji
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties
    Authors: EJ Kim, SG Seo, HS Shin, DJ Lee, JH Kim, DY Lee
    Clin Orthop Surg, 2017;9(2):239-248.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. PPAR? Links BMP2 and TGF?1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism
    Authors: L Calvier, P Chouvarine, E Legchenko, N Hoffmann, J Geldner, P Borchert, D Jonigk, MM Mozes, G Hansmann
    Cell Metab., 2017;25(5):1118-1134.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue
    Authors: C Caër, C Rouault, T Le Roy, C Poitou, J Aron-Wisne, A Torcivia, JC Bichet, K Clément, M Guerre-Mil, S André
    Sci Rep, 2017;7(1):3000.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota
    Authors: Q Zhao, SN Harbour, R Kolde, IJ Latorre, HM Tun, TR Schoeb, H Turner, JJ Moon, E Khafipour, RJ Xavier, CT Weaver, CO Elson
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells
    Authors: K Sakaguchi, W Katagiri, M Osugi, T Kawai, Y Sugimura-W, H Hibi
    Biochem. Biophys. Res. Commun, 2017;484(1):100-106.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  80. XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts
    Authors: K Kamio, A Azuma, J Usuki, K Matsuda, M Inomata, N Nishijima, S Itakura, H Hayashi, T Kashiwada, N Kokuho, K Atsumi, T Yamaguchi, K Fujita, Y Saito, S Abe, K Kubota, A Gemma
    Pulm Pharmacol Ther, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. TGF beta-1 induced CD44v6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis
    Authors: S Ghatak, VC Hascall, RR Markwald, C Feghali-Bo, CM Artlett, M Gooz, GS Bogatkevic, I Atanelishv, RM Silver, J Wood, VJ Thannickal, S Misra
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway
    Authors: YL Li, JT Chang, LY Lee, KH Fan, YC Lu, YC Li, CH Chiang, GR You, HY Chen, AJ Cheng
    Oncotarget, 2017;8(1):1508-1528.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2
    Authors: F Yu, B Chen, X Fan, G Li, P Dong, J Zheng
    Cell. Physiol. Biochem., 2017;43(6):2242-2252.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development
    Authors: SK Sahu, N Tiwari, A Pataskar, Y Zhuang, M Borisova, M Diken, S Strand, P Beli, VK Tiwari
    Nat Commun, 2017;8(1):1523.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Transforming growth factor-?1 signaling promotes epithelial-mesenchymal transition-like phenomena, cell motility, and cell invasion in synovial sarcoma cells
    Authors: Y Qi, N Wang, Y He, J Zhang, H Zou, W Zhang, W Gu, Y Huang, X Lian, J Hu, J Zhao, X Cui, L Pang, F Li
    PLoS ONE, 2017;12(8):e0182680.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis
    Authors: F Pan, H Xiang, J Yan, L Hong, L Zhang, Y Liu, X Feng, C Cai
    Scand. J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Sex, pregnancy and aortic disease in Marfan syndrome
    Authors: M Renard, L Muiño-Mosq, EC Manalo, S Tufa, EJ Carlson, DR Keene, J De Backer, LY Sakai
    PLoS ONE, 2017;12(7):e0181166.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Cdk5 is required for the neuroprotective effect of transforming growth factor-?1 against cerebral ischemia-reperfusion
    Authors: W Zhao, J Yan, L Gao, J Zhao, C Zhao, C Gao, X Luo, X Zhu
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Hydrogen Peroxide Enhances TGF?-mediated Epithelial-to-Mesenchymal Transition in Human Mammary Epithelial MCF-10A Cells
    Authors: D Iizuka, M Sasatani, MH Barcellos-, K Kamiya
    Anticancer Res, 2017;37(3):987-995.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Armc5 deletion causes developmental defects and compromises T-cell immune responses
    Authors: Y Hu, L Lao, J Mao, W Jin, H Luo, T Charpentie, S Qi, J Peng, B Hu, MM Marcinkiew, A Lamarre, J Wu
    Nat Commun, 2017;8(0):13834.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. LINE-1 couples EMT programming with acquisition of oncogenic phenotypes in human bronchial epithelial cells
    Authors: EM Reyes-Reye, I Aispuro, MA Tavera-Gar, M Field, S Moore, I Ramos, KS Ramos
    Oncotarget, 2017;8(61):103828-103842.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  92. TGF?1-induced leucine limitation uncovered by differential ribosome codon reading
    Authors: F Loayza-Puc, K Rooijers, J Zijlstra, B Moumbeini, EA Zaal, JF Oude Vriel, R Lopes, A Pineiro Ug, CR Berkers, R Agami
    EMBO Rep, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia
    Authors: Tsugumi Horikiri
    Respir Med, 2017;122(0):43-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Mesenteric lymph node CD11b(-) CD103(+) PD-L1(High) dendritic cells highly induce regulatory T cells
    Authors: A Shiokawa, R Kotaki, T Takano, H Nakajima-A, S Hachimura
    Immunology, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy
    Authors: J Ko, MK Chae, JH Lee, EJ Lee, JS Yoon
    Invest. Ophthalmol. Vis. Sci., 2017;58(5):2544-2553.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. TGF?-TAZ/SRF Signaling regulates vascular smooth muscle cell differentiation
    Authors: C Pagiatakis, D Sun, SW Tobin, T Miyake, JC McDermott
    FEBS J, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis
    Authors: JJ Kathiriya, N Nakra, J Nixon, PS Patel, V Vaghasiya, A Alhassani, Z Tian, D Allen-Gips, V Davé
    Cell Death Discov, 2017;3(0):17010.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. TGF-? inhibits IL-7-induced proliferation in memory but not naive human CD4(+) T cells
    Authors: TP Nguyen, SF Sieg
    J. Leukoc. Biol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  99. TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition
    Authors: Y Dimitrova, AJ Gruber, N Mittal, S Ghosh, B Dimitriade, D Mathow, WA Grandy, G Christofor, M Zavolan
    Biol. Direct, 2017;12(1):8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammation and Tissue Remodeling
    Authors: D Pap, E Sziksz, Z Kiss, R Rokonay, A Veres-Szék, R Lippai, IM Takács, É Kis, A Fekete, G Reusz, A Vannay, AJ Szabó
    Kidney Blood Press. Res, 2017;42(1):16-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy
    Authors: A Shibata, M Kuno, R Adachi, Y Sato, H Hattori, A Matsuda, Y Okuzono, K Igaki, Y Tominari, T Takagi, M Yabuki, M Okaniwa
    PLoS ONE, 2017;12(10):e0186587.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells
    Authors: L Bai, HM Chang, JC Cheng, C Klausen, G Chu, PCK Leung, G Yang
    Cell. Signal., 2017;37(0):52-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells
    Authors: R Singh, T Miao, ALJ Symonds, B Omodho, S Li, P Wang
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells
    Authors: A Sasahara, K Tominaga, T Nishimura, M Yano, E Kiyokawa, M Noguchi, M Noguchi, H Kanauchi, T Ogawa, H Minato, K Tada, Y Seto, A Tojo, N Gotoh
    Oncotarget, 2017;8(15):24869-24881.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Anti-fibrogenic effect of PPAR-? agonists in human intestinal myofibroblasts
    Authors: JB Koo, MO Nam, Y Jung, J Yoo, DH Kim, G Kim, SJ Shin, KM Lee, KB Hahm, JW Kim, SP Hong, KJ Lee, JH Yoo
    BMC Gastroenterol, 2017;17(1):73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Fibronectin-guided migration of carcinoma collectives
    Authors: S Gopal, L Veracini, D Grall, C Butori, S Schaub, S Audebert, L Camoin, E Baudelet, A Radwanska, S Beghelli-d, SM Violette, PH Weinreb, S Rekima, M Ilie, A Sudaka, P Hofman, E Van Obberg
    Nat Commun, 2017;8(0):14105.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. V-set and Ig domain-containing 4 (VSIG4)-expressing hepatic F4/80+ cells regulate oral antigen-specific responses in mouse
    Authors: W Shin, Y Jeon, I Choi, YJ Kim
    Eur. J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production
    Authors: S Lee, D Kim, J Kang, E Kim, W Kim, H Youn, B Youn
    Cell. Physiol. Biochem., 2017;42(4):1684-1700.
  109. Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells
    Authors: A Siddiqui, ME Vazakidou, A Schwab, F Napoli, C Fernandez-, I Rapa, MP Stemmler, M Volante, T Brabletz, P Ceppi
    J. Pathol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Osteopontin activates mesenchymal stem cells to repair skin wound
    Authors: W Wang, P Li, W Li, J Jiang, Y Cui, S Li, Z Wang
    PLoS ONE, 2017;12(9):e0185346.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. TGF-?1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation
    Authors: JC Cheng, Y Yi, HM Chang, PCK Leung
    Cell. Signal., 2017;43(0):55-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Levistilide A inhibits angiogenesis in liver fibrosis via vascular endothelial growth factor signaling pathway
    Authors: ZM Zhao, HL Liu, X Sun, T Guo, L Shen, YY Tao, CH Liu
    Exp. Biol. Med. (Maywood), 2017;242(9):974-985.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO
    Authors: Nisha Bte Mohd Rafiq
    J. Cell Biol, 2017;216(1):181-197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Arid5a stabilizes OX40 mRNA in murine CD4+ T cells by recognizing a stem-loop structure in its 3'UTR
    Authors: H Hanieh, K Masuda, H Metwally, JP Chalise, M Mohamed, KK Nyati, DM Standley, S Li, M Higa, MM Zaman, T Kishimoto
    Eur. J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites
    Authors: VC Rodríguez-, P Martínez-R, F Català-Mol, J Rodríguez-, A Garcia-Gom, G Poorani-Su, L Ciudad, H Hernando, A Pérez-Garc, C Company, JM Urquiza, AR Ramiro, JM Di Noia, A Vaquero, E Ballestar
    Sci Rep, 2017;7(1):7594.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition
    Authors: D Brethour, M Mehrabian, D Williams, X Wang, F Ghodrati, S Ehsani, EA Rubie, JR Woodgett, J Sevalle, Z Xi, E Rogaeva, G Schmitt-Ul
    Sci Rep, 2017;7(0):40313.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. TGF-?1 (Transforming Growth Factor-?1) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity
    Authors: N Salvarani, A Maguy, SA De Simone, M Miragoli, F Jousset, S Rohr
    Circ Arrhythm Electrophysiol, 2017;10(5):e004567.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients
    Authors: V Ruiz-Carpi, P Sandoval, A Aguilera, P Albar-Vizc, ML Perez-Loza, GT González-M, A Acuña-Ruiz, J García-Can, P Botías, MA Bajo, R Selgas, JA Sánchez-To, J Passlick-D, D Piecha, J Büchel, S Steppan, M López-Cabr
    Sci Rep, 2017;7(0):44941.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis
    Authors: Saverio Bellusci
    Cell Stem Cell, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. MAP3K19 Is a Novel Regulator of TGF-? Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis
    PLoS ONE, 2016;11(5):e0154874.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. The aryl hydrocarbon receptor controls cell-fate decisions in B cells
    Authors: Bharat Vaidyanath
    J. Exp. Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. IL-10 production in murine IgM(+) CD138(hi) cells is driven by Blimp1 and downregulated in class-switched cells
    Eur. J. Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats
    PLoS ONE, 2016;11(8):e0161782.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
    Authors: James B Canavan
    Gut, 2016;65(4):584-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Context-Specific Function of S6K2 in Th Cell Differentiation
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Chemical group-dependent plasma polymerisation preferentially directs adipose stem cell differentiation towards osteogenic or chondrogenic lineages
    Authors: M F Griffin
    Acta Biomater, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  127. TAR DNA-binding protein 43 inhibits inflammatory response and protects chondrocyte function by modulating RACK1 expression in osteoarthritis
    Authors: Xiuyun Zeng
    Biomed. Pharmacother., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
    Authors: Martine Schrøder
    PLoS ONE, 2016;11(6):e0157387.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
    Authors: R Flynn, K Paz, J Du, DK Reichenbac, PA Taylor, A Panoskalts, A Vulic, L Luznik, KK MacDonald, GR Hill, MS Nyuydzefe, JM Weiss, W Chen, A Trzeciak, JS Serody, EG Aguilar, WJ Murphy, I Maillard, D Munn, J Koreth, CS Cutler, JH Antin, J Ritz, SD Waksal, A Zanin-Zhor, BR Blazar
    Blood, 2016;127(17):2144-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases
    Cell Death Dis, 2016;7(12):e2565.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue
    Authors: Mohadeseh Mehrabian
    PLoS ONE, 2016;11(6):e0156779.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition
    Authors: Qisheng Li
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure
    Authors: Shoko Ohno
    Sci Rep, 2016;6(0):27192.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors
    Clin Cancer Res, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-?1 in Airway Epithelium
    PLoS ONE, 2016;11(8):e0162058.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Cell-cell contact and matrix adhesion promote ?SMA expression during TGF?1-induced epithelial-myofibroblast transition via Notch and MRTF-A
    Sci Rep, 2016;6(0):26226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin
    Sci Rep, 2016;6(0):36436.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion
    Authors: Claire Yu
    Biomaterials, 2016;120(0):66-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
    Stem Cell Reports, 2016;0(0):.
    Species: Human
    Sample Types: Protein
    Applications: ELISA Standard
  140. Immunotherapy against Metastatic Melanoma with Human iPS Cell-Derived Myeloid Cell Lines Producing Type I Interferons
    Authors: A Miyashita, S Fukushima, S Nakahara, Y Kubo, A Tokuzumi, J Yamashita, J Aoi, M Haruta, S Senju, Y Nishimura, M Jinnin, H Ihn
    Cancer Immunol Res, 2016;4(3):248-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
    Nat Commun, 2016;7(0):13362.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
    Authors: Sasaki C, Chen G, Munk R, Eitan E, Martindale J, Longo D, Ghosh P
    Eur J Immunol, 2016;46(1):212-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
    Authors: Hoeke A Baarsma
    J. Exp. Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
    Authors: MH Fan, Q Zhu, HH Li, HJ Ra, S Majumdar, DL Gulick, JA Jerome, DH Madsen, M Christofid, DW Speicher, WW Bachovchin, C Feghali-Bo, E Puré
    J. Biol. Chem., 2016;291(15):8070-89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching
    Sci Rep, 2016;6(0):37215.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells
    Cancer Res, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
    EBioMedicine, 2016;10(0):282-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro
    Authors: Brian G Oliver
    Thorax, 2016;71(11):1039-1049.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Altering the Proteoglycan State of Transforming Growth Factor ? Type III Receptor (T?RIII)/Betaglycan Modulates Canonical Wnt/?-Catenin Signaling
    Authors: Karthikeyan Mythreye
    J. Biol. Chem., 2016;291(49):25716-25728.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis
    Sci Rep, 2016;6(0):37445.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas
    PLoS ONE, 2016;11(12):e0167200.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis
    Physiol Rep, 2016;4(17):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Transient RUNX1 Expression during Early Mesendodermal Differentiation of�hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling
    Stem Cell Reports, 2016;7(5):884-896.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease
    Authors: Dong-Chuan Guo
    Am. J. Hum. Genet, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. TGF-?/ SMAD3 Pathway Stimulates Sphingosine-1-phosphate Receptor 3 Expression: Implication of Sphingosine-1-Phosphate Receptor 3 in Lung Adenocarcinoma Progression
    Authors: Menq-Jer Lee
    J. Biol. Chem., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. MEG3 long noncoding RNA contributes to the epigenetic regulation of epithelial-mesenchymal transition in lung cancer cell lines
    Authors: Takeshi Suzuki
    J. Biol. Chem., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Fscn1 is required for the trafficking of TGF-? family type I receptors during endoderm formation
    Nat Commun, 2016;7(0):12603.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-? Small Molecule Inhibitor
    Neoplasia, 2016;18(12):795-805.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Clustering and jamming in epithelial-mesenchymal co-cultures
    Authors: M Gamboa Cas, SE Leggett, IY Wong
    Soft Matter, 2016;12(40):8327-8337.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
    Nat Commun, 2016;7(0):12092.
  161. Lipoxin A4 Attenuates Constitutive and TGF-beta1-Dependent Profibrotic Activity in Human Lung Myofibroblasts.
    Authors: Roach K, Feghali-Bostwick C, Amrani Y, Bradding P
    J Immunol, 2015;195(6):2852-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-beta pathway.
    Authors: Schmitt-Ney M, Camussi G
    PLoS ONE, 2015;10(3):e0121474.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses.
    Authors: Young K, Tweedie E, Conley B, Ames J, FitzSimons M, Brooks P, Liaw L, Vary C
    PLoS ONE, 2015;10(4):e0122892.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy.
    Authors: Pessina P, Cabrera D, Morales M, Riquelme C, Gutierrez J, Serrano A, Brandan E, Munoz-Canoves P
    Skelet Muscle, 2015;4(0):7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  165. TGF-beta1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis.
    Authors: Pang M, Georgoudaki A, Lambut L, Johansson J, Tabor V, Hagikura K, Jin Y, Jansson M, Alexander J, Nelson C, Jakobsson L, Betsholtz C, Sund M, Karlsson M, Fuxe J
    Oncogene, 2015;35(6):748-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis.
    Authors: Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt-Ulms G
    PLoS ONE, 2015;10(8):e0133741.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs.
    Authors: Presnell S, Al-Attar A, Cichocki F, Miller J, Lutz C
    Genes Immun, 2015;16(1):89-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells.
    Authors: Sun, Yue, Deng, Wei, Geng, Linyu, Zhang, Lu, Liu, Rui, Chen, Weiwei, Yao, Genhong, Zhang, Huayong, Feng, Xuebing, Gao, Xiang, Sun, Lingyun
    J Immunol Res, 2015;2015(0):284215.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
    Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
    Invest Ophthalmol Vis Sci, 2015;56(2):1051-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining.
    Authors: Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, Zhang Y
    Proc Natl Acad Sci U S A, 2015;113(5):1256-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development.
    Authors: Wang J, Cao Z, Zhang X, Nakamura M, Sun M, Hartman J, Harris R, Sun Y, Cao Y
    Cancer Res, 2015;75(2):306-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression.
    Authors: Kinugasa H, Whelan K, Tanaka K, Natsuizaka M, Long A, Guo A, Chang S, Kagawa S, Srinivasan S, Guha M, Yamamoto K, St Clair D, Avadhani N, Diehl J, Nakagawa H
    Oncogene, 2015;34(41):5229-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Salinomycin and other polyether ionophores are a new class of antiscarring agent.
    Authors: Woeller C, O'Loughlin C, Roztocil E, Feldon S, Phipps R
    J Biol Chem, 2015;290(6):3563-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. JNK-dependent gene regulatory circuitry governs mesenchymal fate.
    Authors: Sahu S, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, Ortega F, Schmarowski N, Berninger B, Nitsch R, Schmidt M, Tiwari V
    EMBO J, 2015;34(16):2162-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease.
    Authors: Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen B, Nielsen C, Milo R, Zeilig G, Lassmann H, Altmann D, Ben-Nun A
    J Biol Chem, 2015;290(24):15260-78.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Standard
  176. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9.
    Authors: Rojas-Fernandez A, Herhaus L, Macartney T, Lachaud C, Hay R, Sapkota G
    Sci Rep, 2015;5(0):9811.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells.
    Authors: Cruet-Hennequart S, Drougard C, Shaw G, Legendre F, Demoor M, Barry F, Lefaix J, Galera P
    PLoS ONE, 2015;10(3):e0119334.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. 5Z-7-Oxozeanol Inhibits the Effects of TGFbeta1 on Human Gingival Fibroblasts.
    Authors: Kuk H, Hutchenreuther J, Murphy-Marshman H, Carter D, Leask A
    PLoS ONE, 2015;10(4):e0123689.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells.
    Authors: Woltje K, Jabs M, Fischer A
    PLoS ONE, 2015;10(3):e0120547.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Effects of sodium citrate and acid citrate dextrose solutions on cell counts and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel.
    Authors: Giraldo C, Alvarez M, Carmona J
    BMC Vet Res, 2015;11(0):60.
    Species: Equine
    Sample Types: Plasma
  181. High mobility group protein-mediated transcription requires DNA damage marker gamma-H2AX.
    Authors: Singh I, Ozturk N, Cordero J, Mehta A, Hasan D, Cosentino C, Sebastian C, Kruger M, Looso M, Carraro G, Bellusci S, Seeger W, Braun T, Mostoslavsky R, Barreto G
    Cell Res, 2015;25(7):837-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. TGFbeta-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells.
    Authors: Mu Y, Zang G, Engstrom U, Busch C, Landstrom M
    Br J Cancer, 2015;112(7):1223-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-gamma Expression.
    Authors: Lian M, Luo W, Sui Y, Li Z, Hua J
    PLoS ONE, 2015;10(7):e0132741.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation.
    Authors: Narcisi R, Cleary M, Brama P, Hoogduijn M, Tuysuz N, ten Berge D, van Osch G
    Stem Cell Reports, 2015;4(3):459-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Drak2 Does Not Regulate TGF-beta Signaling in T Cells.
    Authors: Harris T, McGargill M
    PLoS ONE, 2015;10(5):e0123650.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
    Authors: Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J
    Nat Med, 2015;21(5):530-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Role and species-specific expression of colon T cell homing receptor GPR15 in colitis.
    Authors: Nguyen L, Pan J, Dinh T, Hadeiba H, O'Hara E, Ebtikar A, Hertweck A, Gokmen M, Lord G, Jenner R, Butcher E, Habtezion A
    Nat Immunol, 2015;16(2):207-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche.
    Authors: Ghiabi P, Jiang J, Pasquier J, Maleki M, Abu-Kaoud N, Halabi N, Guerrouahen B, Rafii S, Rafii A
    J Transl Med, 2015;13(0):27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination.
    Authors: Masani S, Han L, Meek K, Yu K
    Proc Natl Acad Sci U S A, 2015;113(5):1261-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans.
    Authors: Waight J, Takai S, Marelli B, Qin G, Hance K, Zhang D, Tighe R, Lan Y, Lo K, Sabzevari H, Hofmeister R, Wilson N
    J Immunol, 2015;194(3):878-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. 4-1BB ligand signaling to T cells limits T cell activation.
    Authors: Eun S, Lee S, Xu Y, Croft M
    J Immunol, 2015;194(1):134-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  192. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
    Authors: Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, Deng L, Zanvit P, Tu E, Jin W, Abbatiello B, Goldberg N, Chen Q, Sun L, Zhao K, Chen W
    Nat Immunol, 2015;16(10):1077-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes.
    Authors: Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, Anselmi F, Rapelli S, Grillo M, Borghi S, Oliviero S
    Stem Cells, 2015;33(3):742-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. MiR-133 modulates TGF-β1-induced bladder smooth muscle cell hypertrophic and fibrotic response: implication for a role of microRNA in bladder wall remodeling caused by bladder outlet obstruction.
    Cell Signal, 2015;27(2):215-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice.
    Authors: Jia D, Duan F, Peng P, Sun L, Ruan Y, Gu J
    PLoS ONE, 2015;10(3):e0121939.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Suppressor of cytokine signaling 1 is a positive regulator of TGF-beta-induced prostaglandin production in human follicular dendritic cell-like cells.
    Authors: Cho W, Kim Y, Kim J, Park S, Park D, Kim B, Jeoung D, Kim Y, Choe J
    J Immunol, 2015;194(9):4287-97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
    Authors: Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang O, Cochran A, Vasser M, Fauber B, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick D, Lill J, Ouyang W, Dixit V
    Nature, 2015;518(7539):417-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. CXCL13 antibody for the treatment of autoimmune disorders.
    Authors: Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, Jonason A, Mallow C, Doherty M, Paris M, Smith E, Zauderer M
    BMC Immunol, 2015;16(0):6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway.
    Authors: Yu D, Zhang C, Zhao S, Zhang S, Zhang H, Cai S, Shao R, He H
    Acta Pharmacol Sin, 2015;36(4):473-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells.
    Authors: Fujita T, Chiwaki F, Takahashi R, Aoyagi K, Yanagihara K, Nishimura T, Tamaoki M, Komatsu M, Komatsuzaki R, Matsusaki K, Ichikawa H, Sakamoto H, Yamada Y, Fukagawa T, Katai H, Konno H, Ochiya T, Yoshida T, Sasaki H
    PLoS ONE, 2015;10(6):e0130808.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Redox control of p53 in the transcriptional regulation of TGF-beta1 target genes through SMAD cooperativity.
    Authors: Overstreet J, Samarakoon R, Meldrum K, Higgins P
    Cell Signal, 2014;26(7):1427-36.
  202. Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis.
    Authors: Zheng J, Wu C, Lin Z, Guo Y, Shi L, Dong P, Lu Z, Gao S, Liao Y, Chen B, Yu F
    FEBS J, 2014;281(1):88-103.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro.
    Authors: Italiani, Paola, Mazza, Emilia M, Lucchesi, Davide, Cifola, Ingrid, Gemelli, Claudia, Grande, Alexis, Battaglia, Cristina, Bicciato, Silvio, Boraschi, Diana
    PLoS ONE, 2014;9(2):e87680.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Induction of galectin-1 by TGF-beta1 accelerates fibrosis through enhancing nuclear retention of Smad2.
    Authors: Lim M, Ahn J, Yi J, Kim M, Son A, Lee S, Lim D, Kim S, Kang M, Han Y, Song J
    Exp Cell Res, 2014;326(1):125-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.
    Authors: Wei D, Chiang V, Fyne E, Balakrishnan M, Barnes T, Graupe M, Hesselgesser J, Irrinki A, Murry J, Stepan G, Stray K, Tsai A, Yu H, Spindler J, Kearney M, Spina C, McMahon D, Lalezari J, Sloan D, Mellors J, Geleziunas R, Cihlar T
    PLoS Pathog, 2014;10(4):e1004071.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma.
    Authors: Okabe H, Delgado E, Lee J, Yang J, Kinoshita H, Hayashi H, Tsung A, Behari J, Beppu T, Baba H, Monga S
    PLoS ONE, 2014;9(6):e98817.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Musashi-2 controls cell fate, lineage bias, and TGF-beta signaling in HSCs.
    Authors: Park S, Deering R, Lu Y, Tivnan P, Lianoglou S, Al-Shahrour F, Ebert B, Hacohen N, Leslie C, Daley G, Lengner C, Kharas M
    J Exp Med, 2014;211(1):71-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H.
    Authors: Kudo-Saito C, Yura M, Yamamoto R, Kawakami Y
    Cancer Res, 2014;74(5):1361-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Binding of AID to DNA does not correlate with mutator activity.
    Authors: Matthews A, Husain S, Chaudhuri J
    J Immunol, 2014;193(1):252-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis.
    Authors: Gao X, Cao Y, Staloch D, Gonzales M, Aronson J, Chao C, Hellmich M, Ko T
    PLoS ONE, 2014;9(2):e89114.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition.
    Authors: Diepenbruck, Maren, Waldmeier, Lorenz, Ivanek, Robert, Berninger, Philipp, Arnold, Phil, van Nimwegen, Erik, Christofori, Gerhard
    J Cell Sci, 2014;127(0):1523-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis.
    Authors: Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, Hollander A
    Stem Cells Dev, 2014;23(5):541-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Role of Blimp-1 in programing Th effector cells into IL-10 producers.
    Authors: Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kuhl A, Heimesaat M, Esser C, Im S, Radbruch A, Rutz S, Scheffold A
    J Exp Med, 2014;211(9):1807-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF-beta signaling pathway.
    Authors: Wang X, Gui L, Zhang Y, Zhang J, Shi J, Xu G
    Int J Oncol, 2014;44(4):1099-106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
    Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
    PLoS ONE, 2014;9(9):e106673.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Influenza promotes collagen deposition via alphavbeta6 integrin-mediated transforming growth factor beta activation.
    Authors: Jolly L, Stavrou A, Vanderstoken G, Meliopoulos V, Habgood A, Tatler A, Porte J, Knox A, Weinreb P, Violette S, Hussell T, Kolb M, Stampfli M, Schultz-Cherry S, Jenkins G
    J Biol Chem, 2014;289(51):35246-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing.
    Authors: Bohnsack R, Warejcka D, Wang L, Gillespie S, Bernstein A, Twining S, Dahms N
    Invest Ophthalmol Vis Sci, 2014;55(12):7697-708.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Detection of atomic scale changes in the free volume void size of three-dimensional colorectal cancer cell culture using positron annihilation lifetime spectroscopy.
    Authors: Axpe E, Lopez-Euba T, Castellanos-Rubio A, Merida D, Garcia J, Plaza-Izurieta L, Fernandez-Jimenez N, Plazaola F, Bilbao J
    PLoS ONE, 2014;9(1):e83838.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein.
    Authors: Desai L, Zhou Y, Estrada A, Ding Q, Cheng G, Collawn J, Thannickal V
    J Biol Chem, 2014;289(26):18270-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Inhibitory effects of PPARgamma ligands on TGF-beta1-induced corneal myofibroblast transformation.
    Authors: Jeon K, Kulkarni A, Woeller C, Phipps R, Sime P, Hindman H, Huxlin K
    Am J Pathol, 2014;184(5):1429-45.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  222. COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer.
    Authors: Wu Y, Chang T, Huang Y, Huang H, Chou C
    Oncogene, 2014;33(26):3432-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling.
    Authors: Santhekadur P, Akiel M, Emdad L, Gredler R, Srivastava J, Rajasekaran D, Robertson C, Mukhopadhyay N, Fisher P, Sarkar D
    FEBS Open Bio, 2014;4(0):353-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Independent adipogenic and contractile properties of fibroblasts in Graves' orbitopathy: an in vitro model for the evaluation of treatments.
    Authors: Li H, Fitchett C, Kozdon K, Jayaram H, Rose G, Bailly M, Ezra D
    PLoS ONE, 2014;9(4):e95586.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells.
    Authors: Liu R, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, Zhao J, Zhang H
    Int J Oncol, 2014;44(5):1643-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Transforming growth factor beta signaling overcomes dasatinib resistance in lung cancer.
    Authors: Gordian E, Li J, Pevzner Y, Mediavilla-Varela M, Luddy K, Ohaegbulam K, Daniel K, Haura E, Munoz-Antonia T
    PLoS ONE, 2014;9(12):e114131.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Protein tyrosine phosphatase alpha mediates profibrotic signaling in lung fibroblasts through TGF-beta responsiveness.
    Authors: Aschner Y, Khalifah A, Briones N, Yamashita C, Dolgonos L, Young S, Campbell M, Riches D, Redente E, Janssen W, Henson P, Sap J, Vacaresse N, Kapus A, McCulloch C, Zemans R, Downey G
    Am J Pathol, 2014;184(5):1489-502.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  228. MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts.
    Authors: Midgley A, Bowen T, Phillips A, Steadman R
    Aging Cell, 2014;13(2):235-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells.
    Authors: Tobar N, Toyos M, Urra C, Mendez N, Arancibia R, Smith P, Martinez J
    BMC Cancer, 2014;14(0):640.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.
    Authors: Miller C, Haas U, Diaz R, Leeper N, Kundu R, Patlolla B, Assimes T, Kaiser F, Perisic L, Hedin U, Maegdefessel L, Schunkert H, Erdmann J, Quertermous T, Sczakiel G
    PLoS Genet, 2014;10(3):e1004263.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Secreted fibroblast-derived miR-34a induces tubular cell apoptosis in fibrotic kidney.
    Authors: Zhou Y, Xiong M, Niu J, Sun Q, Su W, Zen K, Dai C, Yang J
    J Cell Sci, 2014;127(0):4494-506.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Inhibition of periostin expression protects against the development of renal inflammation and fibrosis.
    Authors: Mael-Ainin M, Abed A, Conway S, Dussaule J, Chatziantoniou C
    J Am Soc Nephrol, 2014;25(8):1724-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Follicular dendritic cell secreted protein FDC-SP controls IgA production.
    Authors: Hou S, Landego I, Jayachandran N, Miller A, Gibson I, Ambrose C, Marshall A
    Mucosal Immunol, 2014;7(4):948-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-beta signaling.
    Authors: Tulley S, Chen W
    J Biol Chem, 2014;289(22):15280-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels.
    Authors: Olderoy M, Lilledahl M, Beckwith M, Melvik J, Reinholt F, Sikorski P, Brinchmann J
    PLoS ONE, 2014;9(3):e91662.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors.
    Authors: Mercer F, Khaitan A, Kozhaya L, Aberg J, Unutmaz D
    J Immunol, 2014;193(3):1047-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGFbeta / GARP-mediated mechanism.
    Authors: Miller M, Petty C, Tompkins M, Fogle J
    Virol J, 2014;11(0):7.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  238. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets.
    Authors: Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, Wei Y, Ouyang F, Chen D, Wu Y, Lao X, Deng H, Zheng L
    J Clin Invest, 2014;124(10):4657-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor.
    Authors: Arts M, Baron M, Chokr N, Fritzler M, Servant M
    PLoS ONE, 2014;9(6):e100035.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-beta signalling.
    Authors: Acuna M, Pessina P, Olguin H, Cabrera D, Vio C, Bader M, Munoz-Canoves P, Santos R, Cabello-Verrugio C, Brandan E
    Hum Mol Genet, 2014;23(5):1237-49.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  241. Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-beta signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts.
    Authors: Schwartze J, Becker S, Sakkas E, Wujak L, Niess G, Usemann J, Reichenberger F, Herold S, Vadasz I, Mayer K, Seeger W, Morty R
    J Biol Chem, 2014;289(6):3262-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. TRPA1 is required for TGF-beta signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma.
    Authors: Okada Y, Shirai K, Reinach P, Kitano-Izutani A, Miyajima M, Flanders K, Jester J, Tominaga M, Saika S
    Lab Invest, 2014;94(9):1030-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  243. The fate of the primary cilium during myofibroblast transition.
    Authors: Rozycki M, Lodyga M, Lam J, Miranda M, Fatyol K, Speight P, Kapus A
    Mol Biol Cell, 2014;25(5):643-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines.
    Authors: Chen L, Munoz-Antonia T, Cress W
    PLoS ONE, 2014;9(7):e101040.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation.
    Authors: Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, Fardel O, Sparfel L
    Eur J Immunol, 2014;44(5):1330-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
    Authors: Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, Woetmann A, Odum N, Bonefeld C, Geisler C
    PLoS ONE, 2014;9(5):e96695.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
    Authors: Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh-hora M, Kodama T, Tanaka S, Bluestone J, Takayanagi H
    Nat Med, 2014;20(1):62-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Gene expression profiles of human adipose tissue-derived mesenchymal stem cells are modified by cell culture density.
    Authors: Kim D, Lee M, Yoo K, Lee T, Kim H, Jang I, Chun Y, Kim H, Park S, Lee S, Son M, Jung H, Sung K, Koo H
    PLoS ONE, 2014;9(1):e83363.
    Species: Human
    Sample Types: Whole Cells
    Applications: cell culture
  249. The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines.
    Authors: Kirkegaard T, Yde C, Kveiborg M, Lykkesfeldt A
    Int J Oncol, 2014;45(1):393-400.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Chromatinized protein kinase C-theta directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.
    Authors: Zafar A, Wu F, Hardy K, Li J, Tu W, McCuaig R, Harris J, Khanna K, Attema J, Gregory P, Goodall G, Harrington K, Dahlstrom J, Boulding T, Madden R, Tan A, Milburn P, Rao S
    Mol Cell Biol, 2014;34(16):2961-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases.
    Authors: Ueda J, Matsuda Y, Yamahatsu K, Uchida E, Naito Z, Korc M, Ishiwata T
    Oncogene, 2014;33(36):4485-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. The anti-proliferative function of the TGF-beta1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3.
    Authors: Li J, Ballim D, Rodriguez M, Cui R, Goding C, Teng H, Prince S
    J Biol Chem, 2014;289(51):35633-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Combined targeting of TGF-beta1 and integrin beta3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer.
    Authors: Salvo E, Garasa S, Dotor J, Morales X, Pelaez R, Altevogt P, Rouzaut A
    Mol Cancer, 2014;13(0):112.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Inhibition by all-trans-retinoic acid of transforming growth factor-beta-induced collagen gel contraction mediated by human tenon fibroblasts.
    Authors: Liu Y, Kimura K, Orita T, Teranishi S, Suzuki K, Sonoda K
    Invest Ophthalmol Vis Sci, 2014;55(7):4199-205.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis.
    Authors: Pan C, Kumar S, Shah N, Hoyt D, Hawinkels L, Mythreye K, Lee N
    J Biol Chem, 2014;289(37):25486-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Arsenic trioxide inhibits transforming growth factor-beta1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.
    Authors: Luo F, Zhuang Y, Sides M, Sanchez C, Shan B, White E, Lasky J
    Respir Res, 2014;15(0):51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  257. Transforming growth factor-beta-induced miR143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo.
    Authors: Cheng T, Hu C, Yang H, Cao L, An J
    Int J Oncol, 2014;45(5):1977-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis.
    Authors: Choi S, Kim B, Robinson J, Fink S, Yan M, Sporn M, Markowitz S, Letterio J
    J Clin Invest, 2014;124(6):2472-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Angiotensin II-dependent TGF-beta signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
    Authors: Gallo E, Loch D, Habashi J, Calderon J, Chen Y, Bedja D, van Erp C, Gerber E, Parker S, Sauls K, Judge D, Cooke S, Lindsay M, Rouf R, Myers L, ap Rhys C, Kent K, Norris R, Huso D, Dietz H
    J Clin Invest, 2014;124(1):448-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo.
    Authors: Rojo J, Ojeda G, Acosta Y, Montes-Casado M, Criado G, Portoles P
    J Leukoc Biol, 2014;95(3):441-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis.
    Authors: Gobel K, Schuhmann M, Pankratz S, Stegner D, Herrmann A, Braun A, Breuer J, Bittner S, Ruck T, Wiendl H, Kleinschnitz C, Nieswandt B, Meuth S
    Eur J Immunol, 2014;44(8):2295-305.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
    Authors: Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S
    EMBO Mol Med, 2014;6(3):322-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells.
    Authors: Matsuhashi S, Hamajima H, Xia J, Zhang H, Mizuta T, Anzai K, Ozaki I
    Cell Signal, 2014;26(3):603-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  264. The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression.
    Authors: Hardin H, Guo Z, Shan W, Montemayor-Garcia C, Asioli S, Yu X, Harrison A, Chen H, Lloyd R
    Am J Pathol, 2014;184(8):2342-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. TGF-beta/Smad3 stimulates stem cell/developmental gene expression and vascular smooth muscle cell de-differentiation.
    Authors: Shi X, DiRenzo D, Guo L, Franco S, Wang B, Seedial S, Kent K
    , 2014;9(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  266. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells.
    Authors: Solomon J, Heitzer M, Liu T, Beumer J, Parise R, Normolle D, Leach D, Buchanan G, DeFranco D
    Mol Cancer Res, 2014;12(8):1166-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-beta and induce Tregs development via TGF-beta.
    Authors: Xu S, Zhu J, Wu Z
    PLoS ONE, 2014;9(3):e91709.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Effective chemoimmunotherapy with anti-TGFbeta antibody and cyclophosphamide in a mouse model of breast cancer.
    Authors: Chen X, Yang Y, Zhou Q, Weiss J, Howard O, McPherson J, Wakefield L, Oppenheim J
    PLoS ONE, 2014;9(1):e85398.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Caffeine and rolipram affect Smad signalling and TGF-beta1 stimulated CTGF and transgelin expression in lung epithelial cells.
    Authors: Fehrholz M, Speer C, Kunzmann S
    PLoS ONE, 2014;9(5):e97357.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5.
    Authors: Ratnayake M, Ploger F, Santibanez-Koref M, Loughlin J
    PLoS ONE, 2014;9(1):e86590.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer.
    Authors: Togashi, Yosuke, Sakamoto, Hiroki, Hayashi, Hidetosh, Terashima, Masato, de Velasco, Marco A, Fujita, Yoshihik, Kodera, Yasuo, Sakai, Kazuko, Tomida, Shuta, Kitano, Masayuki, Ito, Akihiko, Kudo, Masatosh, Nishio, Kazuto
    Mol Cancer, 2014;13(0):126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation.
    Authors: Yu Y, Yiang G, Chou P, Tseng H, Wu T, Hung Y, Lin P, Lin S, Liu H, Chang W, Wei C
    Mol Med Rep, 2014;9(6):2077-84.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  273. A signal transduction pathway from TGF-beta1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma.
    Authors: Qu X, Shen L, Zheng Y, Cui Y, Feng Z, Liu F, Liu J
    J Invest Dermatol, 2014;134(1):159-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils.
    Authors: Baldwin A, Cain S, Lennon R, Godwin A, Merry C, Kielty C
    J Cell Sci, 2014;127(0):158-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  275. MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3.
    Authors: Yao G, Liang M, Liang N, Yin M, Lu M, Lian J, Wang Y, Sun F
    Mol Cell Endocrinol, 2014;382(1):244-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. TGF-beta-activated kinase 1 (TAK1) signaling regulates TGF-beta-induced WNT-5A expression in airway smooth muscle cells via Sp1 and beta-catenin.
    Authors: Kumawat K, Menzen M, Slegtenhorst R, Halayko A, Schmidt M, Gosens R
    PLoS ONE, 2014;9(4):e94801.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  277. The AMPK agonist AICAR inhibits TGF-beta1 induced activation of kidney myofibroblasts.
    Authors: Chen K, Hsu H, Lee C, Yen T, Ko Y, Yang C, Hung C
    PLoS ONE, 2014;9(9):e106554.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis.
    Authors: Karki S, Surolia R, Hock T, Guroji P, Zolak J, Duggal R, Ye T, Thannickal V, Antony V
    FASEB J, 2014;28(3):1122-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice.
    Authors: Haffner-Luntzer, Melanie, Heilmann, Aline, Rapp, Anna Eli, Beie, Simon, Schinke, Thorsten, Amling, Michael, Ignatius, Anita, Liedert, Astrid
    PLoS ONE, 2014;9(12):e116282.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor gammat (RORgammat) in Th17 cells.
    Authors: Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, Zhang J, Xing Y, Chen Z, Tsun A, Li D, Piccioni M, Zhang Y, Guo Q, Jiang L, Bao L, Lv L, Li B
    J Biol Chem, 2014;289(37):25546-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.
    Authors: Kofler D, Marson A, Dominguez-Villar M, Xiao S, Kuchroo V, Hafler D
    J Clin Invest, 2014;124(6):2513-22.
    Species: Human
    Sample Types: Whole Cells
  282. Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
    Authors: Xiao, Guan-Yu, Liu, I-Hsuan, Cheng, Chun-Chu, Chang, Chia-Chu, Lee, Yen-Hua, Cheng, Winston, Wu, Shinn-Ch
    PLoS ONE, 2014;9(9):e106538.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling.
    Authors: Jakobsen R, Ostrup E, Zhang X, Mikkelsen T, Brinchmann J
    PLoS ONE, 2014;9(5):e96615.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. JNK inhibitor SP600125 enhances TGF-beta-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner.
    Authors: Lin Y, Zhang B, Liang H, Lu Y, Ai X, Zhang B, Chen X
    Mol Med Rep, 2013;8(6):1623-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  285. In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo.
    Authors: Zhou Q, Hu Y, Howard O, Oppenheim J, Chen X
    Cytokine, 2013;65(1):56-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. MicroRNA-22 is a master regulator of bone morphogenetic protein-7/6 homeostasis in the kidney.
    Authors: Long, Jianyin, Badal, Shawn S, Wang, Yin, Chang, Benny H, Rodriguez, Antony, Danesh, Farhad R
    J Biol Chem, 2013;288(51):36202-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy.
    Authors: Tammaro A, Stroo I, Rampanelli E, Blank F, Butter L, Claessen N, Takai T, Colonna M, Leemans J, Florquin S, Dessing M
    PLoS ONE, 2013;8(12):e82498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis.
    Authors: Leung L, Radulovich N, Zhu C, Wang D, To C, Ibrahimov E, Tsao M
    PLoS ONE, 2013;8(12):e84366.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. TGF-beta1 regulation of estrogen production in mature rat Leydig cells.
    Authors: Liu M, Wang H, Wang Z, Zhang Y, Chen Y, Zhu F, Zhang Y, Ma J, Li Z
    PLoS ONE, 2013;8(3):e60197.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.
    Authors: Mae, Shin-Ich, Shono, Akemi, Shiota, Fumihiko, Yasuno, Tetsuhik, Kajiwara, Masatosh, Gotoda-Nishimura, Nanaka, Arai, Sayaka, Sato-Otubo, Aiko, Toyoda, Taro, Takahashi, Kazutosh, Nakayama, Naoki, Cowan, Chad A, Aoi, Takashi, Ogawa, Seishi, McMahon, Andrew P, Yamanaka, Shinya, Osafune, Kenji
    Nat Commun, 2013;4(0):1367.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression.
    Authors: Keune W, Sims A, Jones D, Bultsma Y, Lynch J, Jirstrom K, Landberg G, Divecha N
    Cancer Res, 2013;73(23):6913-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  292. MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration.
    Authors: Hanieh H, Alzahrani A
    Eur J Immunol, 2013;43(10):2771-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential.
    Authors: Gu L, Johno H, Nakajima S, Kato H, Takahashi S, Katoh R, Kitamura M
    Lab Invest, 2013;93(4):450-61.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.
    Authors: Serrano, Isabel, McDonald, Paul C, Lock, Frances, Muller, William, Dedhar, Shoukat
    Nat Commun, 2013;4(0):2976.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture.
    Authors: Nguyen H, Zhuang Y, Sun L, Kantrow S, Kolls J, You Z, Zhuo Y, Shan B
    Cancer Cell Int, 2013;13(1):16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.
    Authors: Yanaba K, Kamata M, Ishiura N, Shibata S, Asano Y, Tada Y, Sugaya M, Kadono T, Tedder T, Sato S
    J Leukoc Biol, 2013;94(4):563-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of human tegumentary leishmaniasis.
    Authors: Oliveira W, Ribeiro L, Schrieffer A, Machado P, Carvalho E, Bacellar O
    Cytokine, 2013;66(2):127-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. FOG2 protein down-regulation by transforming growth factor-beta1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy.
    Authors: Park J, Kato M, Yuan H, Castro N, Lanting L, Wang M, Natarajan R
    J Biol Chem, 2013;288(31):22469-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  299. MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms.
    Authors: Liu Y, Yin J, Abou-Kheir W, Hynes P, Casey O, Fang L, Yi M, Stephens R, Seng V, Sheppard-Tillman H, Martin P, Kelly K
    Oncogene, 2013;32(3):296-306.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  300. Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70.
    Authors: Gotz A, Jessberger R
    PLoS ONE, 2013;8(3):e60642.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Bioassay
  301. Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells.
    Authors: Wang C, Yi T, Qin L, Maldonado R, von Andrian U, Kulkarni S, Tellides G, Pober J
    J Clin Invest, 2013;123(4):1677-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination.
    Authors: Masani, Shahnaz, Han, Li, Yu, Kefei
    Mol Cell Biol, 2013;33(7):1468-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  303. TGF-beta mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.
    Authors: Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, Nwajei F, Marini F, Andreeff M, Kuratsu J, Lang F
    Cancer Res, 2013;73(7):2333-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.
    Authors: Ammann J, Cooke A, Trowsdale J
    J Immunol, 2013;190(10):5030-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling.
    Authors: O'Connor J, Gomez E
    PLoS ONE, 2013;8(12):e83188.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-beta/Smad signalling.
    Authors: Romero D, Kawano Y, Bengoa N, Walker M, Maltry N, Niehrs C, Waxman J, Kypta R
    J Cell Sci, 2013;126(0):1858-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis.
    Am J Pathol, 2013;182(1):118-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  308. Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement.
    Authors: Truchetet M, Brembilla N, Montanari E, Lonati P, Raschi E, Zeni S, Fontao L, Meroni P, Chizzolini C
    Arthritis Rheum, 2013;65(5):1347-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  309. TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses.
    Authors: Wang X, Hu Y, Charpentier T, Lamarre A, Qi S, Wu J, Luo H
    J Immunol, 2013;191(11):5420-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Neuropilin-2 Is upregulated in lung cancer cells during TGF-beta1-induced epithelial-mesenchymal transition.
    Authors: Nasarre P, Gemmill R, Potiron V, Roche J, Lu X, Baron A, Korch C, Garrett-Mayer E, Lagana A, Howe P, Drabkin H
    Cancer Res, 2013;73(23):7111-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  311. Canonical transforming growth factor-beta signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29.
    Authors: Ramdas V, McBride M, Denby L, Baker A
    Am J Pathol, 2013;183(6):1885-96.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  312. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs.
    Authors: Chen, Jiekai, Liu, He, Liu, Jing, Qi, Jing, Wei, Bei, Yang, Jiaqi, Liang, Hanquan, Chen, You, Chen, Jing, Wu, Yaran, Guo, Lin, Zhu, Jieying, Zhao, Xiangjie, Peng, Tianran, Zhang, Yixin, Chen, Shen, Li, Xuejia, Li, Dongwei, Wang, Tao, Pei, Duanqing
    Nat Genet, 2013;45(1):34-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-beta1 and platelet-derived growth factor BB.
    Authors: Xu Z, Zhang Q, Li H
    Mol Med Rep, 2013;8(6):1715-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin.
    Authors: Tannetta D, Dragovic R, Gardiner C, Redman C, Sargent I
    PLoS ONE, 2013;8(2):e56754.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands.
    Authors: Stephens G, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M
    Eur J Immunol, 2013;43(7):1727-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition.
    Authors: Balli D, Ustiyan V, Zhang Y, Wang I, Masino A, Ren X, Whitsett J, Kalinichenko V, Kalin T
    EMBO J, 2013;32(2):231-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium.
    Authors: Hojo, Hironori, Ohba, Shinsuke, Taniguchi, Kiyomi, Shirai, Masataka, Yano, Fumiko, Saito, Taku, Ikeda, Toshiyuk, Nakajima, Keiji, Komiyama, Yuske, Nakagata, Naomi, Suzuki, Kentaro, Mishina, Yuji, Yamada, Masahisa, Konno, Tomohiro, Takato, Tsuyoshi, Kawaguchi, Hiroshi, Kambara, Hideki, Chung, Ung-il
    J Biol Chem, 2013;288(14):9924-32.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  318. The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy.
    Authors: Scherz-Shouval R, Santagata S, Mendillo M, Sholl L, Ben-Aharon I, Beck A, Dias-Santagata D, Koeva M, Stemmer S, Whitesell L, Lindquist S
    Cell, 2013;158(3):564-78.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  319. TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis.
    Authors: Geng L, Chaudhuri A, Talmon G, Wisecarver J, Wang J
    PLoS ONE, 2013;8(3):e59918.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Expression regulation of co-inhibitory molecules on human natural killer cells in response to cytokine stimulations.
    Authors: Sun H, Sun C, Xiao W
    Cytokine, 2013;65(1):33-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Role of IGF-1 pathway in lung fibroblast activation.
    Authors: Hung C, Rohani M, Lee S, Chen P, Schnapp L
    Respir Res, 2013;14(0):102.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: cell culture
  322. Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation.
    Authors: Yasmin N, Bauer T, Modak M, Wagner K, Schuster C, Koffel R, Seyerl M, Stockl J, Elbe-Burger A, Graf D, Strobl H
    J Exp Med, 2013;210(12):2597-610.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Tamoxifen ameliorates peritoneal membrane damage by blocking mesothelial to mesenchymal transition in peritoneal dialysis.
    Authors: Loureiro J, Sandoval P, del Peso G, Gonzalez-Mateo G, Fernandez-Millara V, Santamaria B, Bajo M, Sanchez-Tomero J, Guerra-Azcona G, Selgas R, Lopez-Cabrera M, Aguilera A
    PLoS ONE, 2013;8(4):e61165.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Transforming growth factor-beta1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein.
    Authors: Cheng J, Chang H, Leung P
    J Biol Chem, 2013;288(46):33181-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  325. TGF-beta1 promotes lymphangiogenesis during peritoneal fibrosis.
    Authors: Kinashi H, Ito Y, Mizuno M, Suzuki Y, Terabayashi T, Nagura F, Hattori R, Matsukawa Y, Mizuno T, Noda Y, Nishimura H, Nishio R, Maruyama S, Imai E, Matsuo S, Takei Y
    J Am Soc Nephrol, 2013;24(10):1627-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation.
    Authors: Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barre B, Audran M, Bouvard B, Saint-Andre J, Jeannin P
    PLoS Biol, 2012;10(9):e1001395.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis.
    J. Exp. Med., 2012;209(11):2033-47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis.
    Authors: Kudo, Yasusei, Iizuka, Shinji, Yoshida, Maki, Tsunematsu, Takaaki, Kondo, Tomoyuki, Subarnbhesaj, Ajiravud, Deraz, Elsayed, Siriwardena, Samadara, Tahara, Hidetosh, Ishimaru, Naozumi, Ogawa, Ikuko, Takata, Takashi
    J Biol Chem, 2012;287(46):38716-28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15.
    Authors: Mottershead D, Ritter L, Gilchrist R
    Mol Hum Reprod, 2012;18(3):121-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  330. T-Lymphocytes Enable Osteoblast Maturation via IL-17F during the Early Phase of Fracture Repair.
    Authors: Nam D, Mau E, Wang Y, Wright D, Silkstone D, Whetstone H, Whyne C, Alman B
    PLoS ONE, 2012;7(6):e40044.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. TGF beta1-Induced Baf60c Regulates both Smooth Muscle Cell Commitment and Quiescence.
    Authors: Sohni A, Mulas F, Ferrazzi F, Luttun A, Bellazzi R, Huylebroeck D, Ekker S, Verfaillie C
    PLoS ONE, 2012;7(10):e47629.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients.
    Authors: Li J, Mo H, Xiong G, Zhang L, He J, Huang Z, Liu Z, Chen Q, Du Z, Zheng L, Qian C, Zeng Y
    J Biol Chem, 2012;287(42):35484-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway.
    Authors: Bruce D, Macartney T, Yong W, Shou W, Sapkota G
    Cell Signal, 2012;24(11):1999-2006.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. A Local Paracrine and Endocrine Network Involving TGF beta, Cox-2, ROS, and Estrogen Receptor beta Influences Reactive Stromal Cell Regulation of Prostate Cancer Cell Motility.
    Authors: Grubisha MJ, Cifuentes ME, Hammes SR, Defranco DB
    Mol. Endocrinol., 2012;26(6):940-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS.
    Authors: Flanagan K, Fitzgerald K, Baker J
    PLoS ONE, 2012;7(7):e40443.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues.
    Authors: Casey KA, Fraser KA, Schenkel JM, Moran A, Abt MC, Beura LK, Lucas PJ, Artis D, Wherry EJ, Hogquist K, Vezys V, Masopust D
    J. Immunol., 2012;188(10):4866-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
    Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
    Nature, 2012;487(7408):505-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  338. Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
    Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    Am. J. Pathol., 2012;180(1):365-74.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  339. Hic-5 promotes invadopodia formation and invasion during TGF-beta-induced epithelial-mesenchymal transition.
    Authors: Pignatelli J, Tumbarello DA, Schmidt RP, Turner CE
    J. Cell Biol., 2012;197(3):421-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential.
    Authors: Radulovic K, Manta C, Rossini V, Holzmann K, Kestler HA, Wegenka UM, Nakayama T, Niess JH
    J. Immunol., 2012;188(4):2001-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Progenitor-like traits contribute to patient survival and prognosis in oligodendroglial tumors.
    Clin. Cancer Res., 2012;18(15):4122-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  342. Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
    Authors: Huse K, Bakkebo M, Walchli S, Oksvold M, Hilden V, Forfang L, Bredahl M, Liestol K, Alizadeh A, Smeland E, Myklebust J
    PLoS ONE, 2012;7(10):e46117.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis.
    Authors: Krishnan A, Li X, Kao W, Viker K, Butters K, Masuoka H, Knudsen B, Gores G, Charlton M
    Lab Invest, 2012;92(12):1712-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.
    Nat. Med., 2012;1248(0):18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Targeting Axl with an high-affinity inhibitory aptamer.
    Authors: Cerchia, Laura, Esposito, Carla L, Camorani, Simona, Rienzo, Anna, Stasio, Loredana, Insabato, Luigi, Affuso, Andrea, de Franciscis, Vittorio
    Mol Ther, 2012;20(12):2291-303.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Non-Canonical Smads Phosphorylation Induced by the Glutamate Release Inhibitor, Riluzole, through GSK3 Activation in Melanoma.
    Authors: Abushahba W, Olabisi O, Jeong B, Boregowda R, Wen Y, Liu F, Goydos J, Lasfar A, Cohen-Solal K
    PLoS ONE, 2012;7(10):e47312.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
    Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
    PLoS Pathog., 2012;8(1):e1002486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
    Authors: Zheng L, Foley K, Huang L, Leubner A, Mo G, Olino K, Edil BH, Mizuma M, Sharma R, Le DT, Anders RA, Illei PB, Van Eyk JE, Maitra A, Laheru D, Jaffee EM
    PLoS ONE, 2011;6(4):e19390.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  349. Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction.
    Authors: Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K
    Am. J. Pathol., 2011;178(2):572-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha.
    Authors: Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM
    J. Biol. Chem., 2011;286(2):961-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.
    Authors: Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H
    Cell, 2011;147(5):1146-58.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  352. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
    Authors: Jin W, Qi S, Luo H
    BMC Immunol., 2011;12(0):68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  353. HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
    Authors: Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C
    J. Virol., 2011;85(2):1077-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  354. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice.
    Authors: Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirstrom K, Magnusson K, Ebert BL, Ponten F, Weinberg RA, McAllister SS
    J. Clin. Invest., 2011;121(2):784-99.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  355. Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung.
    Authors: Hoffman AM, Paxson JA, Mazan MR, Davis AM, Tyagi S, Murthy S, Ingenito EP
    Stem Cells Dev., 2011;20(10):1779-92.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Down-regulation of Kruppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-{beta} and Bone Morphogenetic Protein 4.
    Authors: Davis-Dusenbery BN, Chan MC, Reno KE, Weisman AS, Layne MD, Lagna G, Hata A
    J. Biol. Chem., 2011;286(32):28097-110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Transcription factor Dlx2 protects from TGFbeta-induced cell-cycle arrest and apoptosis.
    Authors: Yilmaz M, Maass D, Tiwari N, Waldmeier L, Schmidt P, Lehembre F, Christofori G
    EMBO J., 2011;30(21):4489-99.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
    Authors: Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, Tesniere A, Ibrahim N, Dechanet-Merville J, Chaput N, Smyth MJ, Kroemer G, Zitvogel L
    J. Exp. Med., 2011;208(3):491-503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  359. Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation.
    Authors: Duchez S, Pascal V, Cogne N, Jayat-Vignoles C, Julien R, Cogne M
    Eur. J. Immunol., 2011;41(12):3632-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-beta1-dependent human epidermal Langerhans cells.
    Authors: Eisenwort G, Jurkin J, Yasmin N, Bauer T, Gesslbauer B, Strobl H
    J. Invest. Dermatol., 2011;131(10):2049-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  361. Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers.
    Authors: Sierra-Filardi E, Puig-Kroger A, Blanco FJ, Nieto C, Bragado R, Palomero MI, Bernabeu C, Vega MA, Corbi AL
    Blood, 2011;117(19):5092-101.
  362. Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion.
    Authors: Henriksson ML, Edin S, Dahlin AM, Oldenborg PA, Oberg Ã…, Van Guelpen B, Rutegard J, Stenling R, Palmqvist R
    Am. J. Pathol., 2011;178(3):1387-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  363. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011;12(6):568-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  364. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
    Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(34):14222-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  365. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.
    Authors: Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ
    Mol. Biol. Cell, 2011;22(10):1686-98.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
    Authors: Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA
    FASEB J., 2011;25(1):409-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  367. Development and characterisation of an assay for furin activity.
    Authors: Bourne GL, Grainger DJ
    J. Immunol. Methods, 2011;364(1):101-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. NFIL3/E4BP4 controls type 2 T helper cell cytokine expression.
    Authors: Kashiwada M, Cassel SL, Colgan JD
    EMBO J., 2011;30(10):2071-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  369. Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens.
    Authors: DePaolo RW, Abadie V, Tang F
    Nature, 2011;471(7337):220-4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Effects of high mobility group box protein-1, interleukin-1beta, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures.
    Authors: Ley C, Svala E, Nilton A, Lindahl A, Eloranta ML, Ekman S, Skioldebrand E
    Connect. Tissue Res., 2011;52(4):290-300.
    Species: Equine
    Sample Types: Whole Cells
    Applications: Bioassay
  371. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes.
    Authors: Liu F, Chen HY, Huang XR, Chung AC, Zhou L, Fu P, Szalai AJ, Lan HY
    Diabetologia, 2011;54(10):2713-23.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  372. Induction of latency-associated peptide (transforming growth factor-beta(1)) expression on CD4+ T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-alpha production in a transforming growth factor-beta-dependent manner.
    Authors: Boswell S, Sharif S, Alisa A, Pereira SP, Williams R, Behboudi S
    Immunology, 2011;133(3):278-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.
    Authors: Krueger C, Hoffmann FM
    PLoS ONE, 2010;5(11):e15511.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  374. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010;185(4):2502-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism.
    Authors: Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF
    J. Biol. Chem., 2010;285(7):4278-90.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Nuclear function of Smad7 promotes myogenesis.
    Authors: Miyake T, Alli NS, McDermott JC
    Mol. Cell. Biol., 2010;30(3):722-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  377. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
    Authors: Chang HC, Sehra S, Goswami R, Yao W, Yu Q, Stritesky GL, Jabeen R, McKinley C, Ahyi AN, Han L, Nguyen ET, Robertson MJ, Perumal NB, Tepper RS, Nutt SL, Kaplan MH
    Nat. Immunol., 2010;11(6):527-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Regulating human Th17 cells via differential expression of IL-1 receptor.
    Authors: Lee WW, Kang SW, Choi J
    Blood, 2010;115(3):530-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid.
    Authors: Morizane S, Yamasaki K, Kabigting FD, Gallo RL
    J. Invest. Dermatol., 2010;130(5):1297-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site.
    Authors: Tan C, Aziz MK, Lovaas JD, Vistica BP, Shi G, Wawrousek EF, Gery I
    J. Immunol., 2010;185(11):6795-801.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  381. Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein.
    Authors: Bohr W, Kupper M, Hoffmann K, Weiskirchen R
    PLoS ONE, 2010;5(12):e16000.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems.
    Authors: Maupin KA, Sinha A, Eugster E, Miller J, Ross J, Paulino V, Keshamouni VG, Tran N, Berens M, Webb C, Haab BB
    PLoS ONE, 2010;5(9):e13002.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel.
    Authors: Chen G, Hardy K, Bunting K
    J. Immunol., 2010;185(4):2350-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis.
    Authors: Rai D, Kim SW, McKeller MR
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3111-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  385. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
    Authors: Jones GW, McLoughlin RM, Hammond VJ, Parker CR, Williams JD, Malhotra R, Scheller J, Williams AS, Rose-John S, Topley N, Jones SA
    J. Immunol., 2010;184(4):2130-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis.
    Authors: Moransard M, Sawitzky M, Fontana A, Suter T
    Glia, 2010;58(5):559-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  387. TIM-3: a novel regulatory molecule of alloimmune activation.
    Authors: Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N
    J. Immunol., 2010;185(10):5806-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  388. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC.
    Authors: Jindra C
    Eur J Immunol, 2010;40(2):321-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
    Authors: Suzuki K, Maruya M, Kawamoto S
    Immunity, 2010;33(1):71-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.
    Authors: Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ
    Nat. Med., 2010;16(2):191-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
    Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
    J. Exp. Med., 2009;206(1):249-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  392. Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy.
    Authors: van Steensel L, Paridaens D, Schrijver B, Dingjan GM, van Daele PL, van Hagen PM, van den Bosch WA, Drexhage HA, Hooijkaas H, Dik WA
    Invest. Ophthalmol. Vis. Sci., 2009;50(7):3091-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg.
    Authors: Stockis J, Colau D, Coulie PG, Lucas S
    Eur. J. Immunol., 2009;39(12):3315-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus.
    Authors: Dai Z, Turtle CJ, Booth GC, Riddell SR, Gooley TA, Stevens AM, Spies T, Groh V
    J. Exp. Med., 2009;206(4):793-805.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  395. Role of insulin-like growth factor binding protein-3 in allergic airway remodeling.
    Authors: Veraldi KL, Gibson BT, Yasuoka H, Myerburg MM, Kelly EA, Balzar S, Jarjour NN, Pilewski JM, Wenzel SE, Feghali-Bostwick CA
    Am. J. Respir. Crit. Care Med., 2009;180(7):611-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  396. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2009;123(1):179-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  397. Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element.
    Authors: Shafer SL, Towler DA
    J. Mol. Cell. Cardiol., 2009;46(5):621-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  398. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages.
    Authors: Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, Ponsoda S, Delneste Y, Hebbar M, Jeannin P
    Int. J. Cancer, 2009;125(2):367-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. Growth factor regulation of growth factors in articular chondrocytes.
    Authors: Shi S, Mercer S, Eckert GJ, Trippel SB
    J. Biol. Chem., 2009;284(11):6697-704.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling.
    Authors: Pedroja BS, Kang LE, Imas AO, Carmeliet P, Bernstein AM
    J. Biol. Chem., 2009;284(0):20708.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Activation of Toll-like receptor 3 augments myofibroblast differentiation.
    Authors: Sugiura H, Ichikawa T, Koarai A, Yanagisawa S, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M
    Am. J. Respir. Cell Mol. Biol., 2009;40(6):654-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
    Authors: Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F
    Nat. Immunol., 2009;10(8):857-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  403. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
    Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
    Eur. J. Immunol., 2009;39(5):1221-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.
    Authors: Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R
    J. Exp. Med., 2009;206(3):535-48.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  405. CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
    Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
    J. Immunol., 2009;182(1):111-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  406. Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases.
    Authors: Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT
    J. Immunol., 2009;183(3):1739-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  407. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
    Authors: Nolan-Stevaux O, Lau J, Truitt ML, Chu GC, Hebrok M, Fernandez-Zapico ME, Hanahan D
    Genes Dev., 2009;23(1):24-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  408. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009;119(10):1424-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.
    Authors: Sehrawat S, Suryawanshi A, Hirashima M, Rouse BT
    J. Immunol., 2009;182(5):3191-201.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  410. Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism.
    Authors: Lamba S, Ravichandran V, Major EO
    Glia, 2009;57(9):971-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.
    Authors: Bhowmick S, Mazumdar T, Ali N
    Infect. Immun., 2009;77(4):1514-23.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  412. TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
    Authors: Duraisingham SS, Hornig J, Gotch F, Patterson S
    J. Immunol., 2009;183(4):2242-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues.
    Authors: Vitsky A, Waire J, Pawliuk R, Bond A, Matthews D, Lacasse E, Hawes ML, Nelson C, Richards S, Piepenhagen PA, Garman RD, Andrews L, Thurberg BL, Lonning S, Ledbetter S, Ruzek MC
    Am. J. Pathol., 2009;174(6):2137-49.
    Species: N/A
    Sample Types: N/A
    Applications: WB Ctrl
  414. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
    Authors: Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C
    Bone, 2009;44(6):1143-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  415. Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-beta1.
    Authors: Haydont V, Riser BL, Aigueperse J, Vozenin-Brotons MC
    Am. J. Physiol., Cell Physiol., 2008;294(6):C1332-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Both Th1 and Th17 are immunopathogenic but differ in other key biological activities.
    Authors: Cox CA, Shi G, Yin H, Vistica BP, Wawrousek EF, Chan CC, Gery I
    J. Immunol., 2008;180(11):7414-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  417. The anti-inflammatory and anti-angiogenic role of mesenchymal stem cells in corneal wound healing following chemical injury.
    Authors: Oh JY, Kim MK, Shin MS, Lee HJ, Ko JH, Wee WR, Lee JH
    Stem Cells, 2008;26(4):1047-55.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: ELISA development
  418. Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds.
    Authors: Pittet P, Lee K, Kulik AJ, Meister JJ, Hinz B
    J. Cell. Sci., 2008;121(0):877-86.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  419. Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway.
    Authors: Aoudjehane L, Pissaia A, Scatton O, Podevin P, Massault PP, Chouzenoux S, Soubrane O, Calmus Y, Conti F
    Lab. Invest., 2008;88(9):973-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  420. Tumor-specific Th17-polarized cells eradicate large established melanoma.
    Authors: Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann KW, Feigenbaum L, Chan CC, Restifo NP
    Blood, 2008;112(2):362-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  421. Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis.
    Authors: Ke Y, Jiang G, Sun D, Kaplan HJ, Shao H
    Invest. Ophthalmol. Vis. Sci., 2008;49(9):3999-4007.
    Species: Rat
    Sample Types: Aqueous humor
    Applications: Bioassay
  422. alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation.
    Authors: Marsh D, Dickinson S, Neill GW, Marshall JF, Hart IR, Thomas GJ
    Cancer Res., 2008;68(9):3295-303.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.
    Authors: Barbaroux JB, Beleut M, Brisken C, Mueller CG, Groves RW
    J. Immunol., 2008;181(2):1103-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling.
    Authors: Pen A, Moreno MJ, Durocher Y, Deb-Rinker P, Stanimirovic DB
    Oncogene, 2008;27(54):6834-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  425. Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.
    Authors: Kanswal S, Katsenelson N, Selvapandiyan A, Bram RJ, Akkoyunlu M
    J. Immunol., 2008;181(2):976-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  426. Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types.
    Authors: Reed SA, Johnson SE
    J. Cell. Physiol., 2008;215(2):329-36.
    Species: Equine
    Sample Types: Whole Cells
    Applications: Bioassay
  427. Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via smad- and p38-dependent mechanisms.
    Authors: Walsh MF, Ampasala DR, Hatfield J, Vander Heide R, Suer S, Rishi AK, Basson MD
    Am. J. Pathol., 2008;173(2):385-99.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  428. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
    Authors: Guo B, Chang EY, Cheng G
    J. Clin. Invest., 2008;118(5):1680-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
    Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
    J. Allergy Clin. Immunol., 2008;121(6):1385-92, 1392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
    Authors: Fineschi S, Bongiovanni M, Donati Y, Djaafar S, Naso F, Goffin L, Argiroffo CB, Pache JC, Dayer JM, Ferrari-Lacraz S, Chizzolini C
    Am. J. Respir. Cell Mol. Biol., 2008;39(4):458-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  431. Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha.
    Authors: Tsoporis JN, Izhar S, Parker TG
    J. Biol. Chem., 2008;283(44):30174-83.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  432. Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
    Authors: Van Aarsen LA, Leone DR, Ho S, Dolinski BM, McCoon PE, LePage DJ, Kelly R, Heaney G, Rayhorn P, Reid C, Simon KJ, Horan GS, Tao N, Gardner HA, Skelly MM, Gown AM, Thomas GJ, Weinreb PH, Fawell SE, Violette SM
    Cancer Res., 2008;68(2):561-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  433. Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor.
    Authors: Kuchtey J, Kallberg ME, Gelatt KN, Rinkoski T, Komaromy AM, Kuchtey RW
    Invest. Ophthalmol. Vis. Sci., 2008;49(8):3438-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  434. Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.
    Authors: Sheng MH, Wergedal JE, Mohan S, Lau KH
    FEBS Lett., 2008;582(10):1451-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  435. Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus.
    Authors: Anderson BC, Christiansen SP, McLoon LK
    Invest. Ophthalmol. Vis. Sci., 2008;49(1):221-9.
    Species: Rabbit
    Sample Types: In Vivo
    Applications: In Vivo
  436. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.
    Authors: Shinohara ML, Kim JH, Garcia VA, Cantor H
    Immunity, 2008;29(1):68-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  437. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
    Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
    Arthritis Rheum., 2008;58(11):3510-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  438. Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis.
    Authors: Herman S, Muller RB, Kronke G, Zwerina J, Redlich K, Hueber AJ, Gelse H, Neumann E, Muller-Ladner U, Schett G
    Arthritis Rheum., 2008;58(10):3041-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells.
    Authors: Carlson ME, Hsu M, Conboy IM
    Nature, 2008;454(7203):528-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  440. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells.
    Authors: Kato A, Favoreto S, Avila PC, Schleimer RP
    J. Immunol., 2007;179(2):1080-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  441. Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGFbeta.
    Authors: Baker K, Raut P, Jass JR
    J. Pathol., 2007;213(3):257-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells.
    Authors: Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH
    J. Immunol., 2007;179(6):3724-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  443. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.
    Authors: Bujak M, Ren G, Kweon HJ, Dobaczewski M, Reddy A, Taffet G, Wang XF, Frangogiannis NG
    Circulation, 2007;116(19):2127-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  444. Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death.
    Authors: Toscano MA, Bianco GA, Ilarregui JM, Croci DO, Correale J, Hernandez JD, Zwirner NW, Poirier F, Riley EM, Baum LG, Rabinovich GA
    Nat. Immunol., 2007;8(8):825-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  445. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.
    Authors: Brechter AB, Lerner UH
    Arthritis Rheum., 2007;56(3):910-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  446. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.
    Authors: Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW
    Cancer Res., 2007;67(9):4244-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  447. Antitumor activity of ALK1 in pancreatic carcinoma cells.
    Authors: Ungefroren H, Schniewind B, Groth S, Chen WB, Muerkoster SS, Kalthoff H, Fandrich F
    Int. J. Cancer, 2007;120(8):1641-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  448. The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension.
    Authors: Zakrzewicz A, Kouri FM, Nejman B, Kwapiszewska G, Hecker M, Sandu R, Dony E, Seeger W, Schermuly RT, Eickelberg O, Morty RE
    Eur. Respir. J., 2007;29(6):1094-104.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  449. Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling.
    Authors: Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ
    Am. J. Respir. Cell Mol. Biol., 2007;38(1):95-104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  450. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells.
    Authors: Tacke F, Gabele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Scholmerich J, Schnabl B
    Dig. Dis. Sci., 2007;52(12):3404-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  451. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
    Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
    J. Clin. Invest., 2007;117(7):1951-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  452. Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes.
    Authors: Lamar JM, Iyer V, DiPersio CM
    J. Invest. Dermatol., 2007;128(3):575-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  453. Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factor-beta1 response.
    Authors: Korff T, Aufgebauer K, Hecker M
    Circulation, 2007;116(20):2288-97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  454. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin.
    Authors: Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT, Moroney JW, Reed CH, Luban NL, Wang RH, Eling TE, Childs R, Ganz T, Leitman SF, Fucharoen S, Miller JL
    Nat. Med., 2007;13(9):1096-101.
    Species: N/A
    Sample Types: N/A
    Applications: WB Ctrl
  455. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
    Authors: Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J
    Blood, 2007;109(5):2234-42.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  456. Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?
    Authors: McLennan SV, Kelly DJ, Schache M, Waltham M, Dy V, Langham RG, Yue DK, Gilbert RE
    Kidney Int., 2007;72(4):481-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  457. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
    Authors: Ball SG, Shuttleworth CA, Kielty CM
    J. Cell Biol., 2007;177(3):489-500.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  458. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.
    Authors: McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ
    Nat. Immunol., 2007;8(12):1390-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  459. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.
    Authors: Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R
    J. Biol. Chem., 2007;282(32):23337-47.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  460. Bone response and mechanical strength of rabbit femoral defects filled with injectable CaP cements containing TGF-beta 1 loaded gelatin microparticles.
    Authors: Link DP, van den Dolder J, van den Beucken JJ, Wolke JG, Mikos AG, Jansen JA
    Biomaterials, 2007;29(6):675-82.
    Species: Rabbit
    Sample Types: In Vivo
    Applications: In Vivo
  461. Induction of a distinct CD8 Tnc17 subset by transforming growth factor-beta and interleukin-6.
    Authors: Liu SJ, Tsai JP, Shen CR, Sher YP, Hsieh CL, Yeh YC, Chou AH, Chang SR, Hsiao KN, Yu FW, Chen HW
    J. Leukoc. Biol., 2007;82(2):354-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  462. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis.
    Authors: Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Feghali-Bostwick CA, Silver RM
    Arthritis Rheum., 2007;56(7):2432-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  463. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
    Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
    J. Immunol., 2007;178(4):2018-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  464. Differentiation of human circulating fibrocytes as mediated by transforming growth factor-beta and peroxisome proliferator-activated receptor gamma.
    Authors: Hong KM, Belperio JA, Keane MP, Burdick MD, Strieter RM
    J. Biol. Chem., 2007;282(31):22910-20.
  465. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
    Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
    Blood, 2007;109(10):4272-9.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  466. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia.
    Authors: Yue Z, Jiang TX, Widelitz RB, Chuong CM
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(0):951-5.
    Species: Chicken
    Sample Types: In Vivo
    Applications: In Vivo
  467. Multipotent adult progenitor cells from swine bone marrow.
    Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
    Stem Cells, 2006;24(11):2355-66.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  468. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis.
    Authors: Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2006;36(5):1309-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  469. Transforming growth factor-beta1 sensitivity is altered in Abl-Myc- and Raf-Myc-induced mouse pre-B-cell tumors.
    Authors: Letterio J, Rudikoff E, Voong N, Bauer SR
    Stem Cells, 2006;24(12):2611-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  470. IGF-I and IGFBP-3 augment transforming growth factor-beta actions in human renal carcinoma cells.
    Authors: Rosendahl AH, Forsberg G
    Kidney Int., 2006;70(9):1584-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  471. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
    Authors: Létuvé S, Lajoie-Kadoch S, Audusseau S, Rothenberg ME, Fiset PO, Ludwig MS, Hamid Q
    J. Allergy Clin. Immunol., 2006;117(3):590-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  472. Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration.
    Authors: Li Y, Fan J, Chen M, Li W, Woodley DT
    J. Invest. Dermatol., 2006;126(9):2096-105.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  473. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.
    Authors: Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R
    Arthritis Rheum., 2006;54(10):3363-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  474. Isolation of a novel population of multipotent adult stem cells from human hair follicles.
    Authors: Yu H, Fang D, Kumar SM, Li L, Nguyen TK, Acs G, Herlyn M, Xu X
    Am. J. Pathol., 2006;168(6):1879-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  475. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
    Authors: Nguyen AN, Stebbins EG, Henson M, O&amp;amp;apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS
    Exp. Cell Res., 2006;312(10):1909-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  476. Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages.
    Authors: Ogawa K, Funaba M, Chen Y, Tsujimoto M
    J. Immunol., 2006;177(10):6787-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  477. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.
    Authors: Maeshima A, Vaughn DA, Choi Y, Nigam SK
    Dev. Biol., 2006;295(2):473-85.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  478. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.
    Authors: Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK
    Nature, 2006;441(7090):235-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  479. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2006;38(4):497-508.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  480. Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure.
    Authors: Neurohr C, Nishimura SL, Sheppard D
    Am. J. Respir. Cell Mol. Biol., 2006;35(2):252-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  481. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines.
    Authors: Rhodes KE, Raivich G, Fawcett JW
    Neuroscience, 2006;140(1):87-100.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  482. The role of the activin system in keloid pathogenesis.
    Authors: Mukhopadhyay A, Chan SY, Lim IJ, Phillips DJ, Phan TT
    Am. J. Physiol., Cell Physiol., 2006;292(4):C1331-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  483. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo.
    Authors: Andl CD, Fargnoli BB, Okawa T, Bowser M, Takaoka M, Nakagawa H, Klein-Szanto A, Hua X, Herlyn M, Rustgi AK
    Cancer Res., 2006;66(20):9878-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  484. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta.
    Authors: Nagineni CN, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2005;203(1):35-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  485. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.
    Authors: Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM
    Arthritis Rheum., 2005;52(3):770-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  486. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.
    Authors: Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N
    J. Allergy Clin. Immunol., 2005;117(1):103-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  487. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
    Authors: Pound JD, Batth BK, Johannessen I, Wood K
    J. Immunol., 2005;174(5):3015-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  488. Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice.
    Authors: Mesples B, Fontaine RH, Lelievre V, Launay JM, Gressens P
    Neurobiol. Dis., 2005;18(1):193-205.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  489. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
    Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
    J. Immunol., 2004;172(9):5213-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  490. Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype.
    Authors: Leach RE, Kilburn B, Wang J, Liu Z, Romero R, Armant DR
    Dev. Biol., 2004;266(2):223-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  491. Quantification, localization, and expression of IGF-I and TGF-beta1 during growth factor-stimulated fracture healing.
    Authors: Brenner N, Huning M, Stange R
    Calcif. Tissue Int., 2004;74(4):388-97.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  492. Local delivery of growth factors from coated titanium plates increases osteotomy healing in rats.
    Authors: Wildemann B, Bamdad P, Holmer Ch, Haas NP, Raschke M, Schmidmaier G
    Bone, 2004;34(5):862-8.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  493. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
    Authors: Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J
    Arthritis Rheum., 2004;50(8):2521-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  494. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
    Authors: Phillips TM
    Electrophoresis, 2004;25(10):1652-9.
    Species: N/A
    Sample Types: N/A
    Applications: Standard
  495. Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung.
    Authors: Bechara RI, Brown LA, Roman J, Joshi PC, Guidot DM
    Am. J. Respir. Crit. Care Med., 2004;170(2):188-94.
    Species: Mink
    Sample Types: Cell Lysates
    Applications: Bioassay
  496. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
    Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
    J. Immunol., 2004;172(9):5753-64.
    Species: N/A
    Sample Types: N/A
    Applications: WB Ctrl
  497. Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition.
    Authors: Studer RK, Bergman R, Stubbs T, Decker K
    Arthritis Res. Ther., 2004;6(1):R56-R64.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  498. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004;21(2):241-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  499. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.
    Authors: Chen, WanJun, Jin, Wenwen, Hardegen, Neil, Lei, Ke-Jian, Li, Li, Marinos, Nancy, McGrady, George, Wahl, Sharon M
    J Exp Med, 2003;198(12):1875-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  500. Dual roles of IL-4 in lung injury and fibrosis.
    Authors: Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH
    J. Immunol., 2003;170(4):2083-92.
    Species: Mouse
    Sample Types: Whole Cells
  501. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor.
    Authors: Ashcroft GS, Mills SJ, Lei K, Gibbons L, Jeong MJ, Taniguchi M, Burow M, Horan MA, Wahl SM, Nakayama T
    J. Clin. Invest., 2003;111(9):1309-18.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  502. An essential role for Scurfin in CD4+CD25+ T regulatory cells.
    Authors: Khattri, Roli, Cox, Tom, Yasayko, Sue-Ann, Ramsdell, Fred
    Nat Immunol, 2003;4(4):337-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  503. Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice.
    Authors: Cashman J, Clark-Lewis I, Eaves A, Eaves C
    Blood, 2002;99(3):792-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  504. Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.
    Authors: Rosado E, Schwartz Z, Sylvia VL, Dean DD, Boyan BD
    Biochim. Biophys. Acta, 2002;1590(1):1-15.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  505. Suppression of in vivo tumorigenicity of rat hepatoma cell line KDH-8 cells by soluble TGF-beta receptor type II.
    Authors: Zhao W, Kobayashi M, Ding W, Yuan L, Seth P, Cornain S, Wang J, Okada F, Hosokawa M
    Cancer Immunol. Immunother., 2002;51(7):381-8.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  506. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells.
    Authors: Liu X, Kohyama T, Wang H, Zhu YK, Wen FQ, Kim HJ, Romberger DJ, Rennard SI
    Am. J. Physiol. Lung Cell Mol. Physiol., 2002;282(5):L1049-56.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  507. A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.
    Authors: Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D
    J. Immunol., 2002;169(5):2653-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  508. Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta.
    Authors: Schmidt A, Gopfert C, Vlodavsky I, Volker W, Buddecke E
    Eur. J. Cell Biol., 2002;81(3):138-44.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  509. Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice.
    Authors: Scharstuhl A, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB
    Ann. Rheum. Dis., 2002;61(12):1095-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  510. Repeated exposure induces periportal fibrosis in Schistosoma mansoni-infected baboons: role of TGF-beta and IL-4.
    Authors: Farah IO, Mola PW, Kariuki TM, Nyindo M, Blanton RE, King CL
    J. Immunol., 2000;164(10):5337-43.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  511. Growth factors stimulate neointimal cells in vitro and increase the thickness of the neointima formed at the neck of porcine aneurysms treated by embolization.
    Authors: Desfaits AC, 48971, Raymond J, Muizelaar JP
    Cigarette smoke attenuates phagocytic ability of macrophages through down-regulating Milk fat globule-EGF factor 8 (MFG-E8) expressions, 2000;31(0):498-507.
    Species: Canine
    Sample Types: In Vivo
    Applications: In Vivo
  512. Isoform specificity of commercially-available anti-TGF-beta antibodies.
    Authors: Mozes MM, Hodics T, Kopp JB
    J. Immunol. Methods, 1999;225(1):87-93.
    Species: N/A
    Sample Types: N/A
    Applications: WB Ctrl
  513. Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I.
    Authors: Akagi Y, Liu W, Zebrowski B, Xie K, Ellis LM
    Cancer Res., 1998;58(17):4008-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  514. Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1.
    Authors: Villegas V, Rahman M, Fernandez-Barrena M, Diao Y, Liapi E, Sonkoly E, Stahle M, Pivarcsi A, Annaratone L, Sapino A, Ramirez Clavijo S, Burglin T, Shimokawa T, Ramachandran S, Kapranov P, Fernandez-Zapico M, Zaphiropoulos P
    Mol Oncol, 214;8(5):912-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  515. Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-beta.
    Authors: Schmidt A, Zhang X, Joshi R, Iqbal S, Wahlund C, Gabrielsson S, Harris R, Tegner J
    Immunol Cell Biol, 0;94(8):747-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  516. Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate.
    Authors: Schmidt A, Eriksson M, Shang M, Weyd H, Tegner J
    PLoS ONE, 0;11(2):e0148474.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Will Recombinant Human TGF-beta 1 support the maintenance of either human or non-human cultured cells?

    • TGF-beta 1 performs multiple cellular functions, including cell growth, proliferation, differentiation and apoptosis.  It would be necessary to determine the specific conditions for cell growth/proliferation for the cells being cultured.

View all Proteins and Enzyme FAQs

Animal Component Free Recombinant Proteins

Recombinant Human TGF-beta 1, ACFP Protein

ACFP240
1 Review
BA

Reviews for Recombinant Human TGF-beta 1 Protein

Average Rating: 4.6 (Based on 25 Reviews)

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Recombinant Human TGF-beta 1 Protein
By Anonymous on 09/22/2018
Application: In vitro bioactivity in cell culture
In vitro bioactivity in cell culture Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 08/20/2018
Application: Cell proliferation
Recombinant Human TGF-beta 1 Protein
By Anonymous on 08/20/2018
Application: In vitro bioactivity in cell culture
Reason for Rating: Kit was easy to use.
Recombinant Human TGF-beta 1 Protein
By Anonymous on 07/30/2018
Application: In vitro bioactivity in cell culture
In vitro bioactivity in cell culture Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 06/15/2018
Application: Cell Adhesion
Recombinant Human TGF-beta 1 Protein
By Anonymous on 04/18/2018
Application: In vitro bioactivity in cell culture
Reason for Rating: This protein shows really robust effect on Mink lung epithelial cells Mv1Lu, including the robust CDKI induction, SKIP2 downregulation, and the activation of TGFbeta1-reporter.
In vitro bioactivity in cell culture Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 03/28/2018
Application: Binding assay/Protein-protein interaction
Recombinant Human TGF-beta 1 Protein
By Anonymous on 01/24/2018
Application: In vitro bioactivity in cell culture
Reason for Rating: Works very well in tissue culture experiments for pSMAD signal induction and for inducing Ca2+ sparks in muscle cultures
In vitro bioactivity in cell culture Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 01/05/2018
Application: Immunoassay Standard

This protein was used as the standard in an ELISA with antibodies MAB240 and BAF240.

Immunoassay Standard Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 12/01/2017
Application: Binding assay/Protein-protein interaction
Reason for Rating: The protein works perfectly

They work awesome

Binding assay/Protein-protein interaction Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 09/11/2017
Application: In vitro bioactivity in cell culture
Recombinant Human TGF-beta 1 Protein
By Anonymous on 08/30/2017
Application: In vitro bioactivity in cell culture
Recombinant Human TGF-beta 1 Protein
By Anonymous on 05/17/2017
Application: Media additive for protein or antibody production
Reason for Rating: TGFbeta was used to understand EMT process in PANC1 cells and upon treatment we detected classic EMT as anticipated

EMT was induced in PANC1 using TGF beta. EMT markers at both protein and mRNA level were examined using RT PCR and WB. Typical markers of EMT was seen to be altered after TGFbeta treatment in accordance to the desired effect which is induction of EMT

Media additive for protein or antibody production Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 05/02/2017
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Very good and reproducible performance across experiments, lots, and primary T cell donors.Note: Storage conditions are important and product needs to be used within a specified time.

Product used for differentiation of human FOXP3+ cells (regulatory T cells, Tregs) from naive CD4+ T cells, within different experimental setups.

You may add these papers to the references for this product. We name the product in these papers:

Éliás S, Schmidt A, Kannan V, Andersson J, Tegnér J (2016): TGF-β Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner. Frontiers in Immunology 2016 Dec 23;7:603. doi: 10.3389/fimmu.2016.00603. PMID: 28066414.

Schmidt A, Éliás S, Joshi RN, Tegnér J (2016): In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol. Journal of Visualized Experiments 2016 Dec 30;(118). doi: 10.3791/55015. PMID: 28060341.

Schmidt A, Zhang XM, Joshi RN, Iqbal S, Wahlund C, Gabrielsson S, Harris R, Tegnér J (2016): Human macrophages induce CD4+Foxp3+ regulatory T cells via binding and re-release of TGF-β. Immunology & Cell Biology Sep;94(8):747-62. doi: 10.1038/icb.2016.34. PMID: 27075967.

Schmidt A, Eriksson M, Shang MM, Weyd H, Tegnér J (2016): Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL‐2, TGF‐beta, Retinoic Acid, Rapamycin and Butyrate. PLoS ONE 11(2), e0148474. doi:10.1371/journal.pone.0148474. PMID: 26886923.

Stem/Immune cell maintenance or differentiation Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 04/14/2017
Application: T cell differentiation
Reason for Rating: Works well in inducing Foxp3 expression in naive mouse CD4 T cells.

Naive mouse T cells were stimulated with anti-CD3e, anti-CD28, IL-2, and human TGF-beta. Four days later, Foxp3 induction was assessed by intracellular flow cytometry.

T cell differentiation Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 02/20/2017
Application: fibroblast-to-myofibroblast differentiation

TGF-beta stimulation of primary murine lung fibroblasts

Recombinant Human TGF-beta 1 Protein
By Anonymous on 08/08/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: consistent high quality protein that retains activity. Reliable.
Recombinant Human TGF-beta 1 Protein
By Anonymous on 07/23/2016
Application: Stem/Immune cell maintenance or differentiation
Stem/Immune cell maintenance or differentiation Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: Saw morphology changes
In vitro bioactivity in cell culture Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: worked as published results
In vitro bioactivity in cell culture Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 05/12/2016
Application: Cell proliferation
Recombinant Human TGF-beta 1 Protein
By Anonymous on 05/12/2016
Application: Cell migration/motility
Reason for Rating: Used the product at 5ng/mL to induce EMT in primary human epithelial cells. Worked well at 48 hours post-induction with confirmation of EMT by microscopy as well as western for protein markers.
Recombinant Human TGF-beta 1 Protein
By Anonymous on 05/12/2016
Application: Cell proliferation
Recombinant Human TGF-beta 1 Protein
By Anonymous on 01/13/2016
Application: we use it to prepare Metsr medium.
we use it to prepare Metsr medium. Recombinant Human TGF-beta 1 Protein 240-B
Recombinant Human TGF-beta 1 Protein
By Anonymous on 01/13/2016
Application: In vitro bioactivity in cell culture