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Recombinant Mouse IL-4 Protein

Catalog #: 404-ML
399 Citations 16 Reviews Datasheet / COA / SDS

Carrier Free

Catalog # Availability Size / Price Qty
404-ML-010/CF
404-ML-050/CF
404-ML-025/CF
404-ML-100/CF
404-ML-01M/CF

With Carrier

Catalog # Availability Size / Price Qty
404-ML-010
404-ML-050
404-ML-025
404-ML-100
404-ML-01M
Recombinant Mouse IL-4 Protein Bioactivity
2 Images
Product Details
Citations (399)
FAQs
Reviews (16)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse IL-4 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using HT‑2 mouse T cells. The ED50 for this effect is 0.3‑1.5 ng/mL.
Source
E. coli-derived mouse IL-4 protein
His23-Ser140, with an N-terminal Met
Accession #
P07750
N-terminal Sequence
Analysis
His23
Predicted Molecular Mass
14 kDa

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Complete Your Experiment

Recombinant Mouse IL-13 Protein
Cat # 413-ML
Recombinant Mouse GM-CSF Protein
Cat # 415-ML
Recombinant Mouse IFN-gamma Protein
Cat # 485-MI

Product Datasheets

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404-ML (with carrier)

Product Datasheet
COA
SDS

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404-ML/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

404-ML

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

404-ML/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Recombinant Mouse IL-4 Protein Bioactivity View Larger

Recombinant Mouse IL-4 (Catalog # 404-ML) stimulates cell proliferation of the HT‑2 mouse T cell line. The ED50 for this effect is 0.3-1.5 ng/mL.

SDS-PAGE Recombinant Mouse IL-4 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse IL-4 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 12 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-4

Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa-18 kDa Th2 cytokine that shows pleiotropic effects during immune responses (1-4). It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four alpha -helix structure (5). Mouse IL-4 is synthesized with a 24 aa signal sequence. Mature mouse IL-4 shares 39%, 39%, and 59% aa sequence identity with bovine, human, and rat IL-4, respectively. Human, mouse, and rat IL-4 are species-specific in their activities (6-8). IL-4 exerts its effects through two receptor complexes (9, 10). The type I receptor, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and
-21). The type II receptor on nonhematopoietic cells consists of IL‑4 R alpha and IL‑13 R alpha 1. The type II receptor also transduces IL‑13 mediated signals. IL-4 is primarily expressed by Th2‑biased CD4+ T cells, mast cells, basophils, and eosinophils (1, 2). It promotes cell proliferation, survival, and immunoglobulin class switch to IgG1 and IgE in mouse B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells (11 ‑ 14). IL-4 plays a dominant role in the development of allergic inflammation and asthma (13, 15).

References
  1. Benczik, M. and S.L. Gaffen (2004) Immunol. Invest. 33:109.
  2. Chomarat, P. and J. Banchereau (1998) Int. Rev. Immunol. 17:1.
  3. Lee, F. et al. (1986) Proc. Natl. Acad. Sci. 83:2061.
  4. Noma, Y. et al. (1986) Nature 319:640.
  5. Redfield, C. et al. (1991) Biochemistry 30:11029.
  6. Ramirez, F. et al. (1988) J. Immunol. Meth. 221:141.
  7. Leitenberg, D. and T.L. Feldbush (1988) Cell. Immunol. 111:451.
  8. Mosman, T.R. et al. (1987) J. Immunol. 138:1813.
  9. Mueller, T.D. et al. (2002) Biochim. Biophys. Acta 1592:237.
  10. Nelms, K. et al. (1999) Annu. Rev. Immunol. 17:701.
  11. Paludan, S.R. (1998) Scand. J. Immunol. 48:459.
  12. Corthay, A. (2006) Scand. J. Immunol. 64:93.
  13. Ryan, J.J. et al. (2007) Crit. Rev. Immunol. 27:15.
  14. Grone, A. (2002) Vet. Immunol. Immunopathol. 88:1.
  15. Rosenberg, H.F. et al. (2007) J. Allergy Clin. Immunol. 119:1303.
Long Name
Interleukin 4
Entrez Gene IDs
3565 (Human); 16189 (Mouse); 287287 (Rat); 397225 (Porcine); 280824 (Bovine); 403785 (Canine); 574281 (Primate); 100302454 (Rabbit)
Alternate Names
B cell growth factor 1; BCDF; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; IL4; IL-4; IL-4B_cell stimulatory factor 1; IL4E12; interleukin 4; interleukin-4; Lymphocyte stimulatory factor 1; MGC79402; pitrakinra

Citations for Recombinant Mouse IL-4 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

399 Citations: Showing 1 - 10
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  1. Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation
    Authors: R Guo, X Jia, Z Ding, G Wang, M Jiang, B Li, S Chen, B Xia, Q Zhang, J Liu, R Zheng, Z Gao, X Xie
    Theranostics, 2022;12(11):5220-5236.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination
    Authors: SI Tsukumo, PG Subramani, N Seija, M Tabata, Y Maekawa, Y Mori, C Ishifune, Y Itoh, M Ota, K Fujio, JM Di Noia, K Yasutomo
    Science Advances, 2022;8(34):eabq0008.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  3. Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization
    Authors: K Ming-Chin, AA Achuthan, DP De Souza, TJ Lupancu, KJ Binger, MKS Lee, Y Xu, MJ McConville, NA de Weerd, D Dragoljevi, PJ Hertzog, AJ Murphy, JA Hamilton, AJ Fleetwood
    Cell Reports, 2022;39(3):110719.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer
    Authors: MM LaRue, S Parker, J Puccini, M Cammer, AC Kimmelman, D Bar-Sagi
    Proceedings of the National Academy of Sciences of the United States of America, 2022;119(16):e2119168119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  5. Self-assembled BPIV3 nanoparticles can induce comprehensive immune responses and protection against BPIV3 challenge by inducing dendritic cell maturation in mice
    Authors: Z Qu, M Li, R An, H Dai, Y Yu, C Li, C Cao, Y Meng, J Wang, M Gao
    Veterinary Microbiology, 2022;268(0):109415.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Commensal oral microbiota induces osteoimmunomodulatory effects separate from systemic microbiome in mice
    Authors: JD Hathaway-S, JD Aartun, NA Poulides, MB Kuhn, BE McCormick, ME Chew, E Huang, RP Darveau, C Westwater, CM Novince
    JCI Insight, 2022;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing
    Authors: Y Inoue, CW Liao, Y Tsunakawa, IL Tsai, S Takahashi, M Hamada
    International Journal of Molecular Sciences, 2022;23(16):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  8. Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations
    Authors: AP Leinroth, AJ Mirando, D Rouse, Y Kobayahsi, PR Tata, HE Rueckert, Y Liao, JT Long, JV Chakkalaka, MJ Hilton
    Cell Reports, 2022;39(6):110785.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. 53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polalpha-primase fill-in synthesis
    Authors: Z Mirman, NK Sasi, A King, JR Chapman, T de Lange
    Nature Cell Biology, 2022;24(1):51-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects
    Authors: R Mary, F Chalmin, T Accogli, M Bruchard, C Hibos, J Melin, C Truntzer, E Limagne, V Derangère, M Thibaudin, E Humblin, R Boidot, S Chevrier, L Arnould, C Richard, Q Klopfenste, A Bernard, Y Urade, JA Harker, L Apetoh, F Ghiringhel, F Végran
    Cancer Immunology Research, 2022;0(0):OF1-OF17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity
    Authors: CJ Ortiz-Boni, TP Uccello, SA Gerber, EM Lord, EM Messing, YF Lee
    International Journal of Molecular Sciences, 2022;23(6):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis
    Authors: Y Jin, Y Liu, L Xu, J Xu, Y Xiong, Y Peng, K Ding, S Zheng, N Yang, Z Zhang, L Li, L Tan, H Song, J Fu
    Cell Death & Disease, 2022;13(5):512.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32
    Authors: J Yin, H Zeng, K Fan, H Xie, Y Shao, Y Lu, J Zhu, Z Yao, L Liu, H Zhang, B Luo, X Wang, C Zeng, X Bai, H Zhang, D Cai
    Cell Death & Disease, 2022;13(6):567.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
    Authors: C Vasavda, R Xu, J Liew, R Kothari, RS Dhindsa, ER Semenza, BD Paul, DP Green, MF Sabbagh, JY Shin, W Yang, AM Snowman, LK Albacarys, A Moghekar, CA Pardo-Vill, M Luciano, J Huang, C Bettegowda, SG Kwatra, X Dong, M Lim, SH Snyder
    Science Advances, 2022;8(31):eabo5633.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  15. Intratracheal administration of mesenchymal stem cells modulates lung macrophage polarization and exerts anti-asthmatic effects
    Authors: Y Mo, H Kang, JY Bang, JW Shin, HY Kim, SH Cho, HR Kang
    Scientific Reports, 2022;12(1):11728.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Monocyte pro-inflammatory phenotypic control by Ephrin type-A receptor 4 mediates neural tissue damage
    Authors: EA Kowalski, E Soliman, C Kelly, EK Gudenschwa, J Leonard, KJ Pridham, J Ju, AM Cash, A Hazy, C de Jager, AM Kaloss, H Ding, RD Hernandez, GM Coleman, X Wang, ML Olsen, AM Pickrell, MH Theus
    JCI Insight, 2022;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Detection of Radiolabeled Inflammatory Cell Macrophage Subpopulations in Chronic Respiratory Diseases: Results from Preliminary Analyses
    Authors: AP Shaik, AS Shaik, M Abudawood, A Al Faraj
    BioMed Research International, 2022;2022(0):9470845.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload
    Authors: MK Ameka, WN Beavers, CM Shaver, LB Ware, VE Kerchberge, KQ Schoenfelt, L Sun, T Koyama, EP Skaar, L Becker, AH Hasty
    International Journal of Molecular Sciences, 2022;23(13):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization
    Authors: JH Lee, SH Lee, EH Lee, JY Cho, DK Song, YJ Lee, TK Kwon, BC Oh, KW Cho, TF Osborne, TI Jeon, SS Im
    Journal of advanced research, 2022;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling
    Authors: J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su
    Mediators of Inflammation, 2022;2022(0):3441357.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Deleterious Role of Th9 Cells in Pulmonary Fibrosis
    Authors: KM Deng, XS Yang, Q Luo, YX She, QY Yu, XX Tang
    Cells, 2021;10(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Dihydroartemisinin inhibits Lewis Lung carcinoma progression by inducing macrophages M1 polarization via AKT/mTOR pathway
    Authors: X Xiao, Y Li, Y Wang, Y Zhang, J Chen, W Liu, J Tang, F Yue, J Yang
    International immunopharmacology, 2021;103(0):108427.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Polarization
  23. FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation
    Authors: Y Feng, C Li, JA Stewart, P Barbulescu, NS Desivo, A Álvarez-Qu, RC Pezo, MLW Perera, K Chan, AHY Tong, R Mohamad-Ra, M Berru, D Nakib, G Li, GA Kardar, JR Carlyle, J Moffat, D Durocher, JM Di Noia, AS Bhagwat, A Martin
    Nature, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Immunosuppressive effect of Columbianadin on maturation, migration, allogenic T cell stimulation and phagocytosis capacity of TNF-alpha induced dendritic cells
    Authors: S Chen, Y Bai, Y Wang, C Liang, K Du, S Wang, J Li, YX Chang
    Journal of ethnopharmacology, 2021;285(0):114918.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity
    Authors: L Long, J Wei, SA Lim, JL Raynor, H Shi, JP Connelly, H Wang, C Guy, B Xie, NM Chapman, G Fu, Y Wang, H Huang, W Su, J Saravia, I Risch, YD Wang, Y Li, M Niu, Y Dhungana, A Kc, P Zhou, P Vogel, J Yu, SM Pruett-Mil, J Peng, H Chi
    Nature, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection
    Authors: A Di Pietro, J Polmear, L Cooper, T Damelang, T Hussain, L Hailes, K O'Donnell, V Udupa, T Mi, S Preston, A Shtewe, U Hershberg, SJ Turner, NL La Gruta, AW Chung, DM Tarlinton, CD Scharer, KL Good-Jacob
    Nature Immunology, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons
    Authors: Y Shi, S Li, H Zhang, J Zhu, T Che, B Yan, J Li, C Liu
    Journal of Neuroinflammation, 2021;18(1):261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Loop extrusion promotes an alternate pathway for isotype switching
    Authors: HM Shen, R Wuerffel, JF Cantillo, S Priyadarsh, X Lei, J Liang, YL Wu, AL Kenter
    Cell Reports, 2021;37(8):110059.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis
    Authors: H Muto, T Ito, T Tanaka, S Yokoyama, K Yamamoto, N Imai, Y Ishizu, K Maeda, T Honda, T Ishikawa, A Kato, T Ohshiro, F Kano, A Yamamoto, K Sakai, H Hibi, M Ishigami, M Fujishiro
    Scientific Reports, 2021;11(1):18778.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Light-induced dynamic RGD pattern for sequential modulation of macrophage phenotypes
    Authors: Y Luo, X Zheng, P Yuan, X Ye, L Ma
    Bioactive materials, 2021;6(11):4065-4072.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells
    Authors: NR Nabar, CN Heijjer, CS Shi, IY Hwang, S Ganesan, MCI Karlsson, JH Kehrl
    Autophagy, 2021;0(0):19-Jan.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration
    Authors: M Qadri, GD Jay, LX Zhang, TA Schmidt, J Totonchy, KA Elsaid
    Arthritis Research & Therapy, 2021;23(1):241.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease
    Authors: L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen
    Brain, Behavior, and Immunity, 2021;98(0):337-348.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
    Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
    Cell Reports, 2021;36(12):109726.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation
    Authors: JM Motta, VM Rumjanek, A Mantovani, M Locati
    Biomedicines, 2021;9(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  36. Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis
    Authors: M Kurosaka, Y Ogura, S Sato, K Kohda, T Funabashi
    Skeletal Muscle, 2021;11(1):14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection
    Authors: F Zhao, W Kim, H Gao, C Liu, Y Zhang, Y Chen, M Deng, Q Zhou, J Huang, Q Hu, SH Chen, S Nowsheen, JA Kloeber, B Qin, P Yin, X Tu, G Guo, S Qin, C Zhang, M Gao, K Luo, Y Liu, Z Lou, J Yuan
    Nature Cell Biology, 2021;23(8):894-904.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity
    Authors: J Zhou, X Zhang, J Hu, R Qu, Z Yu, H Xu, H Chen, L Yan, C Ding, Q Zou, Y Ye, Z Wang, RA Flavell, HB Li
    Science Advances, 2021;7(25):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication
    Authors: D Wang, J Ma, MV Botuyan, G Cui, Y Yan, D Ding, Y Zhou, EW Krueger, J Pei, X Wu, L Wang, H Pei, MA McNiven, D Ye, G Mer, H Huang
    Science Advances, 2021;7(25):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice
    Authors: D Wan, S Ai, H Ouyang, L Cheng
    Experimental & Molecular Medicine, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity
    Authors: Y Wang, M Song, M Liu, G Zhang, X Zhang, MO Li, X Ma, JJ Zhang, XY Huang
    Cell Reports, 2021;35(1):108948.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Immune modulation mediated by extracellular vesicles of intestinal organoids is disrupted by opioids
    Authors: Y Zhang, Y Yan, J Meng, M Girotra, S Ramakrishn, S Roy
    Mucosal Immunology, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. The effects of myelin on macrophage activation are phenotypic specific via cPLA2 in the context of spinal cord injury inflammation
    Authors: TJ Kopper, B Zhang, WM Bailey, KE Bethel, JC Gensel
    Scientific Reports, 2021;11(1):6341.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases
    Authors: A Sripada, K Sirohi, L Michalec, L Guo, JT McKay, S Yadav, M Verma, J Good, D Rollins, MM Gorska, R Alam
    PloS Biology, 2021;19(3):e3001063.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. CircN4bp1 Facilitates Sepsis-Induced Acute Respiratory Distress Syndrome through Mediating Macrophage Polarization via the miR-138-5p/EZH2 Axis
    Authors: D Zhao, C Wang, X Liu, N Liu, S Zhuang, Q Zhang, X Bao, S Xu, X Zhou, Q Meng, S Li, L Tang
    Mediators of Inflammation, 2021;2021(0):7858746.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-&kappaB pathway
    Authors: Y Lu, L Liu, J Pan, B Luo, H Zeng, Y Shao, H Zhang, H Guan, D Guo, C Zeng, R Zhang, X Bai, H Zhang, D Cai
    Cell Death & Disease, 2021;12(6):533.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  47. Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization
    Authors: VK Rangasami, S Samanta, VS Parihar, K Asawa, K Zhu, OP Varghese, Y Teramura, B Nilsson, J Hilborn, RA Harris, OP Oommen
    Carbohydrate polymers, 2021;254(0):117291.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Pneumococcal Extracellular Vesicles Modulate Host Immunity
    Authors: SS Yerneni, S Werner, JH Azambuja, N Ludwig, R Eutsey, SD Aggarwal, PC Lucas, N Bailey, TL Whiteside, PG Campbell, NL Hiller
    MBio, 2021;0(0):e0165721.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Docosahexaenoic acid ameliorates autoimmune inflammation by activating GPR120 signaling pathway in dendritic cells
    Authors: C Feng, L Li, Q Li, K Switzer, M Liu, S Han, B Zheng
    International immunopharmacology, 2021;97(0):107698.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Hemin-primed dendritic cells suppress allergic airway inflammation through releasing extracellular vesicles
    Authors: Y Wu, Q Yu, M Zhang, Y Zhou, X Su, M Wu, J Lv, Z Xia
    Journal of leukocyte biology, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs
    Authors: A Ortega-Mol, C Lebrero-Fe, A Sanz, N Deleyto-Se, AB Plata-Góme, C Menéndez, O Graña-Cast, E Caleiras, A Efeyan
    Cell Reports, 2021;36(2):109372.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
    Authors: P Francica, M Mutlu, VA Blomen, C Oliveira, Z Nowicka, A Trenner, NM Gerhards, P Bouwman, E Stickel, ML Hekkelman, L Lingg, I Klebic, M van de Ven, R de Korte-G, D Howald, J Jonkers, AA Sartori, W Fendler, JR Chapman, T Brummelkam, S Rottenberg
    Cell Rep, 2020;32(8):108068.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Radiation-induced small extracellular vesicles as "carriages" promote tumor antigen release and trigger antitumor immunity
    Authors: W Lin, Y Xu, X Chen, J Liu, Y Weng, Q Zhuang, F Lin, Z Huang, S Wu, J Ding, L Chen, X Qiu, L Zhang, J Wu, D Lin, S Qiu
    Theranostics, 2020;10(11):4871-4884.
    Species: Mouse
    Sample Types: bone marrow cells
    Applications: Cell Culture
  54. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression
    Authors: JPM Luiz, JE Toller-Kaw, PR Viacava, DC Nascimento, PT Pereira, AL Saraiva, DS Prado, M LeBert, E Giurisato, C Tournier, TM Cunha, FQ Cunha, V Quesniaux, B Ryffel, JC Alves-Filh
    J. Leukoc. Biol., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Myo1e modulates the recruitment of activated B cells to inguinal lymph nodes
    Authors: DA Girón-Pére, E Vadillo, M Schnoor, L Santos-Arg
    J. Cell. Sci., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb
    Authors: D Zhu, TK Johnson, Y Wang, M Thomas, K Huynh, Q Yang, VC Bond, YE Chen, D Liu
    Stem Cell Res Ther, 2020;11(1):162.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Sclerostin expression in trabecular bone is downregulated by osteoclasts
    Authors: M Koide, T Yamashita, K Murakami, S Uehara, K Nakamura, M Nakamura, M Matsushita, T Ara, H Yasuda, JM Penninger, N Takahashi, N Udagawa, Y Kobayashi
    Sci Rep, 2020;10(1):13751.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Lipid mediators and biomarkers associated with type 1 diabetes development
    Authors: AJ Nelson, DJ Stephenson, RN Bone, CL Cardona, MA Park, YG Tusing, X Lei, G Kokotos, CL Graves, CE Mathews, J Kramer, MJ Hessner, CE Chalfant, S Ramanadham
    JCI Insight, 2020;5(16):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice
    Authors: W Lei, R Duan, J Li, X Liu, A Huston, BF Boyce, Z Yao
    Sci Rep, 2020;10(1):7004.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation
    Authors: RK Arya, R Goswami, SO Rahaman
    The Journal of Biological Chemistry, 2020;296(0):100129.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis
    Authors: Y Zhao, J Wang, Z Min, L Peng, S Qi, W Lin
    Mediators Inflamm., 2020;2020(0):6947482.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Effects of senataxin and RNA exosome on B-cell chromosomal integrity
    Authors: D Kazadi, J Lim, G Rothschild, V Grinstein, B Laffleur, O Becherel, MJ Lavin, U Basu
    Heliyon, 2020;6(3):e03442.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  63. Sclerostin expression in trabecular bone is downregulated by osteoclasts
    Authors: M Koide, T Yamashita, K Murakami, S Uehara, K Nakamura, M Nakamura, M Matsushita, T Ara, H Yasuda, JM Penninger, N Takahashi, N Udagawa, Y Kobayashi
    Sci Rep, 2020;10(1):13751.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  64. Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition
    Authors: JM Inclan-Ric, JJ Ponessa, N Valero-Pac, CM Hernandez, CB Sy, AD Lemenze, AM Beaulieu, MC Siracusa
    Nat. Immunol., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
    Authors: L Kealy, A Di Pietro, L Hailes, S Scheer, L Dalit, JR Groom, C Zaph, KL Good-Jacob
    Cell Reports, 2020;33(11):108504.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. The frequency of follicular T helper cells differs in acute and chronic neuroinflammation
    Authors: A Baniahmad, K Birkner, J Görg, J Loos, F Zipp, B Wasser, S Bittner
    Sci Rep, 2020;10(1):20485.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-kappaB Activation for Antibody Class-Switching
    Authors: H Yan, M Fernandez, J Wang, S Wu, R Wang, Z Lou, JB Moroney, CE Rivera, JR Taylor, H Gan, H Zan, D Kolvaskyy, D Liu, P Casali, Z Xu
    J. Immunol., 2020;204(5):1146-1157.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation
    Authors: IS Kang, JS Jang, C Kim
    Sci Rep, 2020;10(1):7024.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  69. CXCL14 Overexpression Attenuates Sepsis-Associated Acute Kidney Injury by Inhibiting Proinflammatory Cytokine Production
    Authors: J Lv, ZL Wu, Z Gan, P Gui, SL Yao
    Mediators Inflamm., 2020;2020(0):2431705.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway
    Authors: R Yang, G Wang, L Li, H He, M Zheng, L Lu, S Wu
    J Transl Med, 2020;18(1):444.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  71. Adjuvant activity of Mycobacteria-derived mycolic acids
    Authors: M Kubota, E Iizasa, Y Chuuma, H Kiyohara, H Hara, H Yoshida
    Heliyon, 2020;6(5):e04064.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. A Novel Selective Sphingosine Kinase 2 Inhibitor, HWG-35D, Ameliorates the Severity of Imiquimod-Induced Psoriasis Model by Blocking Th17 Differentiation of Na�ve CD4 T Lymphocytes
    Authors: SH Shin, HY Kim, HS Yoon, WJ Park, DR Adams, NJ Pyne, S Pyne, JW Park
    Int J Mol Sci, 2020;21(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its anti-inflammatory properties
    Authors: CY Han, I Kang, M Omer, S Wang, T Wietecha, TN Wight, A Chait
    JCI Insight, 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
    Authors: J Tur, S Pereira-Lo, T Vico, EA Marín, JP Muñoz, M Hernández-, PJ Cardona, A Zorzano, J Lloberas, A Celada
    Cell Rep, 2020;32(8):108079.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Environmental arginine controls multinuclear giant cell metabolism and formation
    Authors: JS Brunner, L Vulliard, M Hofmann, M Kieler, A Lercher, A Vogel, M Russier, JB Brüggenthi, M Kerndl, V Saferding, B Niederreit, A Junza, A Frauenstei, C Scholtysek, Y Mikami, K Klavins, G Krönke, A Bergthaler, JJ O'Shea, T Weichhart, F Meissner, JS Smolen, P Cheng, O Yanes, J Menche, PJ Murray, O Sharif, S Blüml, G Schabbauer
    Nat Commun, 2020;11(1):431.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  76. Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
    Authors: DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee
    Cytokine, 2020;137(0):155334.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. TGF-beta2 interfering oligonucleotides used as adjuvants for microbial vaccines
    Authors: L Tu, X Sun, L Yang, T Zhang, X Zhang, X Li, B Dong, Y Liu, M Yang, L Wang, Y Yu
    J. Leukoc. Biol., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Mechanotransduction via a TRPV4-Rac1 signaling axis plays a role in multinucleated giant cell formation
    Authors: RK Arya, R Goswami, SO Rahaman
    The Journal of Biological Chemistry, 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  79. Isoliquiritigenin ameliorates caerulein-induced chronic pancreatitis by inhibiting the activation of PSCs and pancreatic infiltration of macrophages
    Authors: LJ Wang, L He, L Hao, HL Guo, XP Zeng, YW Bi, GT Lu, ZS Li, LH Hu
    J. Cell. Mol. Med., 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  80. Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition
    Authors: JM Inclan-Ric, JJ Ponessa, N Valero-Pac, CM Hernandez, CB Sy, AD Lemenze, AM Beaulieu, MC Siracusa
    Nat. Immunol., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial &gamma&delta T cell compartments
    Authors: A Jandke, D Melandri, L Monin, DS Ushakov, AG Laing, P Vantourout, P East, T Nitta, T Narita, H Takayanagi, R Feederle, A Hayday
    Nat Commun, 2020;11(1):3769.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  82. Tumors induce de novo steroid biosynthesis in T cells to evade immunity
    Authors: B Mahata, J Pramanik, L van der We, K Polanski, G Kar, A Riedel, X Chen, NA Fonseca, K Kundu, LS Campos, E Ryder, G Duddy, I Walczak, K Okkenhaug, DJ Adams, JD Shields, SA Teichmann
    Nat Commun, 2020;11(1):3588.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
    Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
    Cell Rep, 2020;31(13):107820.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Airway-Associated Macrophages in Homeostasis and Repair
    Authors: AE Engler, AB Ysasi, RMF Pihl, C Villacorta, HM Heston, HMK Richardson, BR Thapa, NR Moniz, AC Belkina, SA Mazzilli, JR Rock
    Cell Reports, 2020;33(13):108553.
    Species: Transgenic Mouse
    Sample Types: Spheroid
    Applications: Bioassay
  85. Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation
    Authors: MA Maqbool, L Pioger, AZ El Aabidin, N Karasu, AM Molitor, LTM Dao, G Charbonnie, F van Laethe, R Fenouil, F Koch, G Lacaud, I Gut, M Gut, S Amigorena, O Joffre, T Sexton, S Spicuglia, JC Andrau
    Cell Rep, 2020;32(7):108048.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  86. HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization
    Authors: ML Li, XM Su, Y Ren, X Zhao, LF Kong, J Kang
    Respir. Res., 2020;21(1):62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  87. Anticancer Activity of Liquid Treated with Microwave Plasma-Generated Gas through Macrophage Activation
    Authors: CB Lee, IH Seo, MW Chae, JW Park, EH Choi, HS Uhm, KY Baik
    Oxid Med Cell Longev, 2020;2020(0):2946820.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  88. B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response
    Authors: H Gan, T Shen, DP Chupp, JR Taylor, HN Sanchez, X Li, Z Xu, H Zan, P Casali
    Sci Adv, 2020;6(14):eaay2793.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  89. mRNA Vaccines Encoding the HA Protein of Influenza A H1N1 Virus Delivered by Cationic Lipid Nanoparticles Induce Protective Immune Responses in Mice
    Authors: X Zhuang, Y Qi, M Wang, N Yu, F Nan, H Zhang, M Tian, C Li, H Lu, N Jin
    Vaccines (Basel), 2020;8(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  90. Serine/threonine phosphatase PP2A is essential for optimal B cell function
    Authors: E Meidan, H Li, W Pan, M Kono, S Yu, VC Kyttaris, C Ioannidis, N Rodriguez, JC Crispin, SA Apostolidi, P Lee, J Manis, A Sharabi, MG Tsokos, GC Tsokos
    JCI Insight, 2020;5(5):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  91. Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
    Authors: P Francica, M Mutlu, VA Blomen, C Oliveira, Z Nowicka, A Trenner, NM Gerhards, P Bouwman, E Stickel, ML Hekkelman, L Lingg, I Klebic, M van de Ven, R de Korte-G, D Howald, J Jonkers, AA Sartori, W Fendler, JR Chapman, T Brummelkam, S Rottenberg
    Cell Rep, 2020;32(8):108068.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response
    Authors: D Prantner, S Nallar, K Richard, D Spiegel, KD Collins, SN Vogel
    J. Leukoc. Biol., 2020;0(0):.
    Species: Mouse
    Sample Types: Primary Cells
    Applications: Cell Culture
  93. An Erg-driven transcriptional program controls B cell lymphopoiesis
    Authors: AP Ng, HD Coughlan, S Hediyeh-Za, K Behrens, TM Johanson, MSY Low, CC Bell, O Gilan, YC Chan, AJ Kueh, T Boudier, R Feltham, A Gabrielyan, L DiRago, CD Hyland, H Ierino, S Mifsud, E Viney, T Willson, MA Dawson, RS Allan, MJ Herold, K Rogers, DM Tarlinton, GK Smyth, MJ Davis, SL Nutt, WS Alexander
    Nat Commun, 2020;11(1):3013.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
    Authors: FC Simões, TJ Cahill, A Kenyon, D Gavriouchk, JM Vieira, X Sun, D Pezzolla, C Ravaud, E Masmanian, M Weinberger, S Mayes, ME Lemieux, DN Barnette, M Gunadasa-R, RM Williams, DR Greaves, LA Trinh, SE Fraser, SL Dallas, RP Choudhury, T Sauka-Spen, PR Riley
    Nat Commun, 2020;11(1):600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Lipid mediators and biomarkers associated with type 1 diabetes development
    Authors: AJ Nelson, DJ Stephenson, RN Bone, CL Cardona, MA Park, YG Tusing, X Lei, G Kokotos, CL Graves, CE Mathews, J Kramer, MJ Hessner, CE Chalfant, S Ramanadham
    JCI Insight, 2020;5(16):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation
    Authors: MA Maqbool, L Pioger, AZ El Aabidin, N Karasu, AM Molitor, LTM Dao, G Charbonnie, F van Laethe, R Fenouil, F Koch, G Lacaud, I Gut, M Gut, S Amigorena, O Joffre, T Sexton, S Spicuglia, JC Andrau
    Cell Rep, 2020;32(7):108048.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  97. Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
    Authors: J Tur, S Pereira-Lo, T Vico, EA Marín, JP Muñoz, M Hernández-, PJ Cardona, A Zorzano, J Lloberas, A Celada
    Cell Rep, 2020;32(8):108079.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Immunoglobulin Class Switch Recombination is initiated by rare cytosine deamination events at switch regions
    Authors: A Kim, L Han, K Yu
    Mol. Cell. Biol., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Modulation of the humoral immune response by constitutively active STAT6 expression in murine B cells
    Authors: P Haase, L Mokada-Gop, D Radtke, D Voehringer
    Eur. J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  100. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
    Authors: A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies
    Br. J. Cancer, 2019;121(7):556-566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
    Authors: E Khattar, KZY Maung, CL Chew, A Ghosh, MMH Mok, P Lee, J Zhang, WHJ Chor, G Cildir, CQ Wang, NK Mohd-Ismai, DWL Chin, SC Lee, H Yang, YJ Shin, DH Nam, L Chen, AP Kumar, LW Deng, M Ikawa, J Gunaratne, M Osato, V Tergaonkar
    Nat Commun, 2019;10(1):5349.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
    Authors: S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, R Srinivasan, X Li, K Devarajan, L Prélot, CE Ang, Y Shibuya, BA Benayoun, ALS Chang, M Wernig, J Wysocka, MT Longaker, MP Snyder, A Brunet
    Nature, 2019;574(7779):553-558.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  103. Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice
    Authors: GR Martin, CM Blomquist, KL Henare, FR Jirik
    Sci Rep, 2019;9(1):14281.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  104. Anti-cervical carcinoma effect of Portulaca oleracea L. polysaccharides by oral administration on intestinal dendritic cells
    Authors: R Zhao, X Shao, G Jia, Y Huang, Z Liu, B Song, J Hou
    BMC Complement Altern Med, 2019;19(1):161.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340
    Authors: Y Mu, J Zhang, Y Liu, J Ma, D Jiang, X Zhang, X Yi, K Cheng, S Shen, Y Yang, R Zhuang, Y Zhang
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
    Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
    Mediators Inflamm., 2019;2019(0):9086758.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  107. Dendritic cells and M2 macrophage play an important role in suppression of Th2-mediated inflammation by adipose stem cells-derived extracellular vesicles
    Authors: KS Cho, SA Kang, SD Kim, SJ Mun, HS Yu, HJ Roh
    Stem Cell Res, 2019;39(0):101500.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation
    Authors: JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Impact of aging on transition of acute kidney injury to chronic kidney disease
    Authors: MG Kim, J Yang, YS Ko, HY Lee, SW Oh, WY Cho, SK Jo
    Sci Rep, 2019;9(1):18445.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Cathepsin L secretion by host and neoplastic cells potentiates invasion
    Authors: SS Dykes, HO Fasanya, DW Siemann
    Oncotarget, 2019;10(53):5560-5568.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
    Authors: LP Garo, AK Ajay, M Fujiwara, V Beynon, C Kuhn, G Gabriely, S Sadhukan, R Raheja, S Rubino, HL Weiner, G Murugaiyan
    Cell Rep, 2019;28(13):3353-3366.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  112. Injectable human recombinant collagen matrices limit adverse remodeling and improve cardiac function after myocardial infarction
    Authors: S McLaughlin, B McNeill, J Podrebarac, K Hosoyama, V Sedlakova, G Cron, D Smyth, R Seymour, K Goel, W Liang, KJ Rayner, M Ruel, EJ Suuronen, EI Alarcon
    Nat Commun, 2019;10(1):4866.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  113. The Notch ligand DNER regulates macrophage IFN? release in chronic obstructive pulmonary disease
    Authors: C Ballester-, TM Conlon, Z Ertüz, FR Greiffo, M Irmler, SE Verleden, J Beckers, IE Fernandez, O Eickelberg, AÖ Yildirim
    EBioMedicine, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE
    Authors: X Han, S Huang, P Xue, J Fu, L Liu, C Zhang, L Yang, L Xia, L Sun, SK Huang, Y Zhou
    Sci Adv, 2019;5(12):eaax9230.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  115. Vitamin D improves sunburns by increasing autophagy in M2 macrophages
    Authors: LM Das, AM Binko, ZP Traylor, H Peng, KQ Lu
    Autophagy, 2019;0(0):1-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation
    Authors: M Bolger-Mun, K Choi, JM Scurll, L Abraham, RS Chappell, D Sheen, M Dang-Lawso, X Wu, JJ Priatel, D Coombs, JA Hammer, MR Gold
    Elife, 2019;8(0):.
    Species: Complex Species Category
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization
    Authors: CP Hans, N Sharma, S Sen, S Zeng, R Dev, Y Jiang, A Mahajan, T Joshi
    Sci Rep, 2019;9(1):7999.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1
    Authors: AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, AR Johnson, JJ Milner, MF Lim, JA Galanko, MA Beck, JE Bear, JD Rotty, L Bezavada, HS Smallwood, MA Puchowicz, J Liu, JW Locasale, DP Lee, BJ Bennett, ED Abel, JC Rathmell, L Makowski
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  119. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
    Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  120. Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe
    Authors: PM Ryan, EH Stolte, LEE London, JM Wells, SL Long, SA Joyce, CGM Gahan, GF Fitzgerald, RP Ross, NM Caplice, C Stanton
    BMC Microbiol., 2019;19(1):33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses
    Authors: JN Pucella, M Cols, WF Yen, S Xu, J Chaudhuri
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Ampk regulates IgD expression but not energy stress with B cell activation
    Authors: LR Waters, FM Ahsan, J Ten Hoeve, JS Hong, DNH Kim, A Minasyan, D Braas, TG Graeber, TA Zangle, MA Teitell
    Sci Rep, 2019;9(1):8176.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis
    Authors: JD Jones, BP Sinder, D Paige, FN Soki, AJ Koh, S Thiele, Y Shiozawa, LC Hofbauer, S Daignault, H Roca, LK McCauley
    Neoplasia, 2019;21(2):172-184.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease
    Authors: W Fonseca, AJ Rasky, C Ptaschinsk, SH Morris, SKK Best, M Phillips, CA Malinczak, NW Lukacs
    Mucosal Immunol, 2019;12(2):445-456.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity
    Authors: MT Rached, SJ Millership, SMA Pedroni, AI Choudhury, ASH Costa, DG Hardy, JA Glegola, EE Irvine, C Selman, MC Woodberry, VK Yadav, S Khadayate, A Vidal-Puig, S Virtue, C Frezza, DJ Withers
    Mol Metab, 2019;20(0):38-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
    Authors: K Yasuda, Y Kitagawa, R Kawakami, Y Isaka, H Watanabe, G Kondoh, T Kohwi-Shig, S Sakaguchi, K Hirota
    Nat Commun, 2019;10(1):549.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis
    Authors: P Handa, S Thomas, V Morgan-Ste, BD Maliken, E Gochanour, S Boukhar, MM Yeh, KV Kowdley
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis
    Authors: YB Kim, YH Ahn, JH Jung, YJ Lee, JH Lee, JL Kang
    Cell. Mol. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism
    Authors: J Liu, L Zhu, J Wang, L Qiu, Y Chen, RE Davis, G Cheng
    PLoS Pathog., 2019;15(6):e1007817.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Cutting Edge: ATM Influences Germinal Center Integrity
    Authors: L Nicolas, M Cols, R Smolkin, KC Fernandez, WT Yewdell, WF Yen, S Zha, BQ Vuong, J Chaudhuri
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Distinct Requirements of CHD4 during B Cell Development and Antibody Response
    Authors: WF Yen, R Sharma, M Cols, CM Lau, A Chaudhry, P Chowdhury, WT Yewdell, B Vaidyanath, A Sun, M Coffre, JN Pucella, CC Chen, M Jasin, JC Sun, AY Rudensky, SB Koralov, J Chaudhuri
    Cell Rep, 2019;27(5):1472-1486.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. CD45Rb-low effector T cells require IL-4 to induce IL-10 in FoxP3 Tregs and to protect mice from inflammation
    Authors: MB Jones, CA Alvarez, JL Johnson, JY Zhou, N Morris, BA Cobb
    PLoS ONE, 2019;14(5):e0216893.
    Species: Mouse
    Sample Types: cell culture
    Applications: cell cutlure
  133. The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice
    Authors: VV Kurilin, JN Khantakova, VP Tereschenk, JA Lopatnikov, IA Obleukhova, SV Sennikov
    J Immunol Res, 2019;2019(0):7029726.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. High activation of STAT5A drives peripheral T-cell lymphoma and leukemia
    Authors: B Maurer, H Nivarthi, B Wingelhofe, HTT Pham, M Schlederer, T Suske, R Grausenbur, AI Schiefer, M Prchal-Mur, D Chen, S Winkler, O Merkel, C Kornauth, M Hofbauer, B Hochgatter, G Hoermann, A Hoelbl-Kov, J Prochazkov, C Lobello, AA Cumaraswam, J Latzka, M Kitzwögere, A Chott, A Janikova, Š Pospíšilov, JI Loizou, S Kubicek, P Valent, T Kolbe, F Grebien, L Kenner, PT Gunning, R Kralovics, M Herling, M Müller, T Rülicke, V Sexl, R Moriggl
    Haematologica, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling
    Authors: X Liu, P Zhang, Y Zhang, Z Wang, S Xu, Y Li, W Huai, Q Zhou, X Chen, X Chen, N Li, P Wang, Y Li, X Cao
    Cell Res., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation
    Authors: W Sun, N Meednu, A Rosenberg, J Rangel-Mor, V Wang, J Glanzman, T Owen, X Zhou, H Zhang, BF Boyce, JH Anolik, L Xing
    Nat Commun, 2018;9(1):5127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage
    Authors: S Nowsheen, K Aziz, K Luo, M Deng, B Qin, J Yuan, KB Jeganathan, J Yu, H Zhang, W Ding, JM van Deurse, Z Lou
    Nat Commun, 2018;9(1):2736.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection
    Authors: HA Ting, D de Almeida, AJ Rasky, CA Malinczak, IP Maillard, MA Schaller, NW Lukacs
    Mucosal Immunol, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  139. The shieldin complex mediates 53BP1-dependent DNA repair
    Authors: SM Noordermee, S Adam, D Setiaputra, M Barazas, SJ Pettitt, AK Ling, M Olivieri, A Álvarez-Qu, N Moatti, M Zimmermann, S Annunziato, DB Krastev, F Song, I Brandsma, J Frankum, R Brough, A Sherker, S Landry, RK Szilard, MM Munro, A McEwan, T Goullet de, ZY Lin, T Hart, J Moffat, AC Gingras, A Martin, H van Attiku, J Jonkers, CJ Lord, S Rottenberg, D Durocher
    Nature, 2018;560(7716):117-121.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation
    Authors: M Becerra-Dí, AB Strickland, A Keselman, NM Heller
    J. Immunol., 2018;0(0):.
  141. Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins
    Authors: S Trezise, A Karnowski, PL Fedele, S Mithraprab, Y Liao, K D'Costa, AJ Kueh, MP Hardy, CM Owczarek, MJ Herold, A Spencer, W Shi, SN Willis, SL Nutt, LM Corcoran
    Int J Mol Sci, 2018;19(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
    Authors: G Meyer Zu H, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, R Sobel, A Regev, VK Kuchroo
    Immunity, 2018;48(3):556-569.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Mechanisms underlying immune tolerance caused by recombinant Echinococcus granulosus antigens Eg mMDH and Eg10 in dendritic cells
    Authors: Y Wang, S Lv, Q Wang, C Wang, M Zhu, Z Ma, W Zhao
    PLoS ONE, 2018;13(9):e0204868.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners
    Authors: C Farruggia, MB Kim, M Bae, Y Lee, TX Pham, Y Yang, MJ Han, YK Park, JY Lee
    J. Nutr. Biochem., 2018;62(0):202-209.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. LACC1 Regulates TNF and IL-17 in Mouse Models of Arthritis and Inflammation
    Authors: C Skon-Hegg, J Zhang, X Wu, M Sagolla, N Ota, A Wuster, J Tom, E Doran, N Ramamoorth, P Caplazi, J Monroe, WP Lee, TW Behrens
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes
    Authors: H Chiu, LV Jackson, KI Oh, A Mai, ZA Ronai, D Ruggero, DA Fruman
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
    Authors: AN Billin, SE Honeycutt, AV McDougal, JP Kerr, Z Chen, JM Freudenber, DK Rajpal, G Luo, HF Kramer, RS Geske, F Fang, B Yao, RV Clark, J Lepore, A Cobitz, R Miller, K Nosaka, AC Hinken, AJ Russell
    Skelet Muscle, 2018;8(1):35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis
    Authors: C Rossi, M Cusimano, M Zambito, A Finardi, A Capotondo, JM Garcia-Man, G Comi, R Furlan, G Martino, L Muzio
    Cell Death Dis, 2018;9(2):250.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
    Authors: G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud
    Cell Rep, 2018;25(8):2163-2176.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84
    Authors: L Gagnon, M Leduc, JF Thibodeau, MZ Zhang, B Grouix, F Sarra-Bour, W Gagnon, K Hince, M Tremblay, L Geerts, CRJ Kennedy, RL Hébert, A Gutsol, CE Holterman, E Kamto, L Gervais, J Ouboudinar, J Richard, A Felton, A Laverdure, JC Simard, S Létourneau, MP Cloutier, FA Leblond, SD Abbott, C Penney, JS Duceppe, B Zacharie, J Dupuis, A Calderone, QT Nguyen, RC Harris, P Laurin
    Am. J. Pathol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  151. Activated leukocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy
    Authors: YS Kim, MN Kim, KE Lee, JY Hong, MS Oh, SY Kim, KW Kim, MH Sohn
    Clin. Exp. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA
    Authors: D Menolfi, W Jiang, BJ Lee, T Moiseeva, Z Shao, V Estes, MG Frattini, CJ Bakkenist, S Zha
    Nat Commun, 2018;9(1):5351.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Differential Phagocytic Properties of CD45lowMicroglia and CD45highBrain Mononuclear Phagocytes-Activation and Age-Related Effects
    Authors: S Rangaraju, SA Raza, NX Li, R Betarbet, EB Dammer, D Duong, JJ Lah, NT Seyfried, AI Levey
    Front Immunol, 2018;9(0):405.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
    Authors: A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai
    Front Immunol, 2018;9(0):22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  155. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation
    Authors: X Xiao, Y Fan, J Li, X Zhang, X Lou, Y Dou, X Shi, P Lan, Y Xiao, L Minze, XC Li
    J. Exp. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  156. Chronic Alterations in Systemic Immune Function After Traumatic Brain Injury
    Authors: R Ritzel, S Doran, J Barrett, R Henry, E Ma, A Faden, DJ Loane
    J. Neurotrauma, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  157. Crucial role of OX40/OX40L signaling in a murine model of asthma
    Authors: W Lei, D Zeng, G Liu, Y Zhu, J Wang, H Wu, J Jiang, J Huang
    Mol Med Rep, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Collagen-derived peptides modulate CD4T-cell differentiation and suppress allergic responses in mice
    Authors: A Nishikimi, YI Koyama, S Ishihara, S Kobayashi, C Tometsuka, M Kusubata, K Kuwaba, O Hayashida, S Hattori, K Katagiri
    Immun Inflamm Dis, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. REV-ERB? Regulates TH17 Cell Development and Autoimmunity
    Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
    Cell Rep, 2018;25(13):3733-3749.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Characterization and allergic role of IL-33-induced neutrophil polarization
    Authors: B Sun, L Zhu, Y Tao, HX Sun, Y Li, P Wang, Y Hou, Y Zhao, X Zhang, L Zhang, N Na, Y Zhao
    Cell. Mol. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Enhanced Pro-Inflammatory Response of Macrophages to Interleukin-33 in an Allergic Environment
    Authors: N Chia, RK Kumar, PS Foster, C Herbert
    Int. Arch. Allergy Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression
    Authors: Y Han, Q Liu, J Hou, Y Gu, Y Zhang, Z Chen, J Fan, W Zhou, S Qiu, Y Zhang, T Dong, N Li, Z Jiang, H Zhu, Q Zhang, Y Ma, L Zhang, Q Wang, Y Yu, N Li, X Cao
    Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis
    Authors: M Chen, J Zhao, IH Ali, S Marry, J Augustine, M Bhuckory, A Lynch, A Kissenpfen, H Xu
    Am. J. Pathol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Duox1 Regulates Primary B Cell Function under the Influence of IL-4 through BCR-Mediated Generation of Hydrogen Peroxide
    Authors: R Sugamata, A Donko, Y Murakami, HE Boudreau, CF Qi, J Kwon, TL Leto
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
    Authors: S Nowsheen, K Aziz, A Aziz, M Deng, B Qin, K Luo, KB Jeganathan, H Zhang, T Liu, J Yu, Y Deng, J Yuan, W Ding, JM van Deurse, Z Lou
    Nat. Cell Biol., 2018;20(4):455-464.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. ?M?2Is Antiatherogenic in Female but Not Male Mice
    Authors: D Szpak, L Izem, D Verbovetsk, DA Soloviev, VP Yakubenko, E Pluskota
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial�Changes
    Authors: Y Kasagi, PM Chandramou, KA Whelan, K Tanaka, V Giroux, M Sharma, J Wang, AJ Benitez, M DeMarshall, JW Tobias, KE Hamilton, GW Falk, JM Spergel, AJ Klein-Szan, AK Rustgi, AB Muir, H Nakagawa
    Cell Mol Gastroenterol Hepatol, 2018;5(3):333-352.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  168. Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis
    Authors: C Youssif, M Cubillos-R, M Comalada, E Llonch, C Perna, N Djouder, AR Nebreda
    EMBO Mol Med, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming
    Authors: L Simula, I Pacella, A Colamatteo, C Procaccini, V Cancila, M Bordi, C Tregnago, M Corrado, M Pigazzi, V Barnaba, C Tripodo, G Matarese, S Piconese, S Campello
    Cell Rep, 2018;25(11):3059-3073.e10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs
    Authors: CD Scharer, BG Barwick, M Guo, APR Bally, JM Boss
    Nat Commun, 2018;9(1):1698.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Endogenous protection from ischemic brain injury by preconditioned monocytes
    Authors: L Garcia-Bon, D Brea, C Benakis, D Lane, M Murphy, J Moore, G Racchumi, X Jiang, C Iadecola, J Anrather
    J. Neurosci., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. A new RelB-dependent CD117+CD172a+murine dendritic cell subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo
    Authors: N Andreas, M Riemann, CN Castro, M Groth, I Koliesnik, C Engelmann, T Sparwasser, T Kamradt, R Haenold, F Weih
    Eur. J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist
    Authors: K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park, JH Ju
    PLoS ONE, 2018;13(2):e0193086.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  174. B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation
    Authors: BG Barwick, CD Scharer, RJ Martinez, MJ Price, AN Wein, RR Haines, APR Bally, JE Kohlmeier, JM Boss
    Nat Commun, 2018;9(1):1900.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining
    Authors: C Li, T Irrazabal, CC So, M Berru, L Du, E Lam, AK Ling, JL Gommerman, Q Pan-Hammar, A Martin
    Nat Commun, 2018;9(1):1006.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution
    Authors: MJ Tol, MJC van der Li, TL Gabriel, JJ Hagen, S Scheij, T Veenendaal, J Klumperman, WE Donker-Koo, AJ Verhoeven, H Overkleeft, JM Aerts, CA Argmann, M van Eijk
    Autophagy, 2018;0(0):1-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. CD11b regulates antibody class switching via induction of AID
    Authors: S Park, H Sim, HI Kim, D Jeong, G Wu, SY Cho, YS Lee, HJ Kwon, K Lee
    Mol. Immunol., 2017;87(0):47-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function
    Authors: T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. The Small Rho GTPase TC10 Modulates B Cell Immune Responses
    Authors: M Burbage, SJ Keppler, B Montaner, PK Mattila, FD Batista
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells
    Authors: KA Read, MD Powell, CE Baker, BK Sreekumar, VM Ringel-Sca, H Bachus, RE Martin, ID Cooley, IC Allen, A Ballestero, KJ Oestreich
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB
    Authors: SN Willis, J Tellier, Y Liao, S Trezise, A Light, K O'Donnell, LA Garrett-Si, W Shi, DM Tarlinton, SL Nutt
    Nat Commun, 2017;8(1):1426.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Utilization of host polyamines in alternatively activated macrophages promotes chronic infection by Brucella abortus
    Authors: T Kerrinnes, MG Winter, BM Young, VE Diaz-Ochoa, SE Winter, RM Tsolis
    Infect. Immun., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill,, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017;2(17):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  184. mTORC2 controls Th9 polarization and allergic airway inflammation
    Authors: H Chen, L Zhang, P Wang, H Su, W Wang, Z Chu, L Zhang, X Zhang, Y Zhao
    Allergy, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs
    Authors: CH Son, J Bae, HR Lee, K Yang, YS Park
    Oncol Lett, 2017;13(5):3781-3786.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease
    Authors: T Minamitani, Y Ma, H Zhou, H Kida, CY Tsai, M Obana, D Okuzaki, Y Fujio, A Kumanogoh, B Zhao, H Kikutani, E Kieff, BE Gewurz, T Yasui
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  187. The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells
    Authors: J Geng, S Yu, H Zhao, X Sun, X Li, P Wang, X Xiong, L Hong, C Xie, J Gao, Y Shi, J Peng, RL Johnson, N Xiao, L Lu, J Han, D Zhou, L Chen
    Nat. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma
    Authors: S Mroczek, J Chlebowska, TM Kuli?ski, O Gewartowsk, J Gruchota, D Cysewski, V Liudkovska, E Borsuk, D Nowis, A Dziembowsk
    Nat Commun, 2017;8(1):619.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Crosstalk between glucocorticoids and IL-4 modulates Ym1 expression in alternatively activated myeloid cells
    Authors: N Ng Kuet Le, F Brombacher, AH Dalpke, M Weitnauer
    Immunobiology, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Interleukin 4 receptor-targeted pro-apoptotic peptide blocks tumor growth and metastasis by enhancing anti-tumor immunity
    Authors: SMP Vadevoo, JE Kim, GR Gunassekar, HK Jung, L Chi, DE Kim, SH Lee, SH Im, B Lee
    Mol. Cancer Ther., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs
    Authors: J Wang, H Ye, D Zhang, K Cheng, Y Hu, X Yu, L Lu, J Hu, C Zuo, B Qian, Y Yu, S Liu, G Liu, C Mao, S Liu
    Theranostics, 2017;7(6):1407-1421.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Pro-inflammatory M1 macrophages promote osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway
    Authors: LY Lu, F Loi, K Nathan, TH Lin, J Pajarinen, E Gibon, A Nabeshima, L Cordova, E Jämsen, Z Yao, SB Goodman
    J. Orthop. Res, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Soluble TNF Regulates TACE via AP-2? Transcription Factor in Mouse Dendritic Cells
    Authors: L Ge, NL Vujanovic
    J. Immunol., 2017;198(1):417-427.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
    Authors: S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen
    Sci Rep, 2017;7(0):42846.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1
    Authors: G Fu, Q Xu, Y Qiu, X Jin, T Xu, S Dong, J Wang, Y Ke, H Hu, X Cao, D Wang, H Cantor, X Gao, L Lu
    J. Exp. Med., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis
    Authors: L Mokada-Gop, A Boeser, CH Lehmann, F Drepper, D Dudziak, B Warscheid, D Voehringer
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination
    Authors: H Zan, C Tat, Z Qiu, JR Taylor, JA Guerrero, T Shen, P Casali
    Nat Commun, 2017;8(0):14244.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Bone-induced expression of integrin ?3 enables targeted nanotherapy of breast cancer metastases
    Authors: MH Ross, AK Esser, GC Fox, AH Schmieder, X Yang, G Hu, D Pan, X Su, Y Xu, DV Novack, T Walsh, GA Colditz, GH Lukaszewic, E Cordell, JS Novack, JAJ Fitzpatric, DL Waning, KS Mohammad, TA Guise, GM Lanza, KN Weilbaeche
    Cancer Res., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. IL-4 upregulates cyclooxygenase-1 expression in macrophages
    Authors: AE Shay, BT Diwakar, BJ Guan, V Narayan, JF Urban, KS Prabhu
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages
    Authors: DC Cockrell, CM Long, SJ Robertson, JG Shannon, HE Miller, L Myers, CL Larson, T Starr, PA Beare, RA Heinzen
    PLoS ONE, 2017;12(3):e0173528.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  201. The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis
    Authors: X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang
    Sci Rep, 2017;7(1):5107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells
    Authors: W Dawicki, C Li, J Town, X Zhang, JR Gordon
    J. Allergy Clin. Immunol., 2017;139(5):1608-1620.e3.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA (Standard)
  203. Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats
    Authors: H Huang, J Liu, H Hao, D Chen, L Zhizhong, M Li, H Song, R Xiang, C Jiang, X Fu, W Han
    Stem Cells Int, 2017;2017(0):2896874.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection
    Authors: RM Valanparam, M Tam, PP Gros, JP Auger, M Segura, P Gros, A Jardim, TG Geary, K Ozato, MM Stevenson
    PLoS Pathog., 2017;13(10):e1006647.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  205. Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency
    Authors: YY Sin, PR Price, LL Ballantyne, CD Funk
    Sci Rep, 2017;7(1):2585.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  206. IL-4-secreting eosinophils promote endometrial stromal cell proliferation and prevent Chlamydia-induced upper genital tract damage
    Authors: RD Vicetti Mi, NE Quispe Cal, D Dixon, RA Foster, A Gambotto, SD Pavelko, L Hall-Stood, TL Cherpes
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Detection of immune responses after immunotherapy in glioblastoma using PET and MRI
    Authors: JP Antonios, H Soto, RG Everson, DL Moughon, AC Wang, J Orpilla, C Radu, BM Ellingson, JT Lee, T Cloughesy, ME Phelps, J Czernin, LM Liau, RM Prins
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk
    Authors: V Piccolo, A Curina, M Genua, S Ghisletti, M Simonatto, A Sabò, B Amati, R Ostuni, G Natoli
    Nat. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. TIRR regulates 53BP1 by masking its histone methyl-lysine binding function
    Authors: P Drané, ME Brault, G Cui, K Meghani, S Chaubey, A Detappe, N Parnandi, Y He, XF Zheng, MV Botuyan, A Kalousi, WT Yewdell, C Münch, JW Harper, J Chaudhuri, E Soutoglou, G Mer, D Chowdhury
    Nature, 2017;543(7644):211-216.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  210. TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy
    Authors: J Ye, Y Wang, X Liu, L Li, A Opejin, EC Hsueh, H Luo, T Wang, D Hawiger, G Peng
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. The Crebbp Acetyltransferase is a Haploinsufficient Tumor Suppressor in B Cell Lymphoma
    Authors: J Zhang, S Vlasevska, VA Wells, S Nataraj, AB Holmes, R Duval, SN Meyer, T Mo, K Basso, PK Brindle, S Hussein, R Dalla-Fave, L Pasqualucc
    Cancer Discov, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway
    Authors: J Zhu, K Yao, J Guo, H Shi, L Ma, Q Wang, H Liu, W Gao, A Sun, Y Zou, J Ge
    J. Cell. Mol. Med., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
    Authors: DK Chiu, AP Tse, IM Xu, J Di Cui, RK Lai, LL Li, HY Koh, FH Tsang, LL Wei, CM Wong, IO Ng, CC Wong
    Nat Commun, 2017;8(1):517.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
    Authors: DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh
    Nat Commun, 2017;8(0):14919.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Balanced Bcl-3 expression in murine CD4(+) T cells is required for generation of encephalitogenic Th17 cells
    Authors: IA Mufazalov, J Kuschmann, D Andruszews, J Masri, LA Gabriel, P Adams, S Reissig, N Hövelmeyer, A Waisman
    Eur. J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells
    Authors: T Rivera Var, Z Cai, Y Shen, M Dosset, I Benoit-Liz, T Martin, A Roussey, RA Flavell, F Ghiringhel, L Apetoh
    Nat Commun, 2017;8(1):559.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry
    Authors: J Lim, PK Giri, D Kazadi, B Laffleur, W Zhang, V Grinstein, E Pefanis, LM Brown, E Ladewig, O Martin, Y Chen, R Rabadan, F Boyer, G Rothschild, M Cogné, E Pinaud, H Deng, U Basu
    Cell, 2017;169(3):523-537.e15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
    Authors: R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton
    Cardiovasc Diabetol, 2017;16(1):143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity
    Authors: A Rialdi, J Hultquist, D Jimenez-Mo, Z Peralta, L Campisi, R Fenouil, N Moshkina, ZZ Wang, B Laffleur, RM Kaake, MJ McGregor, K Haas, E Pefanis, RA Albrecht, L Pache, S Chanda, J Jen, J Ochando, M Byun, U Basu, A García-Sas, N Krogan, H van Bakel, I Marazzi
    Cell, 2017;169(4):679-692.e14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus
    Authors: Ahmed S Elshikha
    PLoS ONE, 2016;11(5):e0156583.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
    Sci Rep, 2016;6(0):37211.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization
    J Immunol, 2016;196(11):4536-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
    Nat Commun, 2016;7(0):11624.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Cutting Edge: Marginal Zone Macrophages Regulate Antigen Transport by B Cells to the Follicle in the Spleen via CD21
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. IL-12p40/IL-10 Producing preCD8?/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection
    Authors: D Torres, A Köhler, S Delbauve, I Caminschi, MH Lahoud, K Shortman, V Flamand
    PLoS Pathog, 2016;12(4):e1005561.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. M2-polarized macrophages contribute to neovasculogenesis, leading to relapse of oral cancer following radiation
    Authors: Makiko Okubo
    Sci Rep, 2016;6(0):27548.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
    Circ Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  228. p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
    Authors: Sasaki C, Chen G, Munk R, Eitan E, Martindale J, Longo D, Ghosh P
    Eur J Immunol, 2016;46(1):212-22.
  229. M1/M2-macrophage phenotypes regulate renal calcium oxalate crystal development.
    Authors: Kazumi Taguchi, Atsushi Okada, Shuzo Hamamoto, Rei Unno, Yoshinobu Moritoki, Ryosuke Ando, Kentaro Mizuno, Keiichi Tozawa, Kenjiro Kohri, Takahiro Yasui
    Scientific Reports, 2016;0(0):2045-2322.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching
    Sci Rep, 2016;6(0):37215.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE
    Authors: Yee Ling Wu
    J. Exp. Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
    Sci Rep, 2016;6(0):37977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
    Authors: Shweta Pasi
    J Biol Chem, 2016;291(23):12358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKC? Kinase Activity
    Authors: E Naik, VM Dixit
    J Immunol, 2016;196(8):3438-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  235. The aryl hydrocarbon receptor controls cell-fate decisions in B cells
    Authors: Bharat Vaidyanath
    J. Exp. Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy
    J. Immunol., 2016;197(12):4750-4761.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  237. A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells
    Authors: Mithun Maji
    Sci Rep, 2016;6(0):27206.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)
    PLoS ONE, 2016;11(5):e0155953.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis
    Authors: C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  241. VISTA deficiency accelerates the development of fatal murine lupus nephritis
    Authors: Sabrina Ceeraz
    Arthritis & rheumatology (Hoboken, N.J.), 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain
    Mol Immunol, 2016;77(0):184-192.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  243. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific ?? T Cell Compartments
    Authors: R Di Marco B, NA Roberts, RJ Dart, P Vantourout, A Jandke, O Nussbaumer, L Deban, S Cipolat, R Hart, ML Iannitto, A Laing, B Spencer-De, P East, D Gibbons, PM Irving, P Pereira, U Steinhoff, A Hayday
    Cell, 2016;167(1):203-218.e17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-?3 production
    Proc. Natl. Acad. Sci. U.S.A., 2016;113(50):E8131-E8140.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function
    J Leukoc Biol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer.
    Authors: Gao F, Liu C, Guo J, Sun W, Xian L, Bai D, Liu H, Cheng Y, Li B, Cui J, Zhang C, Cai J
    Sci Rep, 2015;5(0):9613.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination.
    Authors: Masani S, Han L, Meek K, Yu K
    Proc Natl Acad Sci U S A, 2015;113(5):1261-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  248. The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
    Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
    J Leukoc Biol, 2015;98(3):395-407.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  249. IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism.
    Authors: Zhao Y, Zhao H, Sun Y, Hao J, Qi X, Zhou X, Wu Z, Wang P, Kaech S, Weaver C, Flavell R, Zhao L, Yao Z, Yin Z
    J Leukoc Biol, 2015;94(6):1103-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining.
    Authors: Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, Zhang Y
    Proc Natl Acad Sci U S A, 2015;113(5):1256-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Sca-1+Lin-CD117- mesenchymal stem/stromal cells induce the generation of novel IRF8-controlled regulatory dendritic cells through Notch-RBP-J signaling.
    Authors: Liu X, Ren S, Ge C, Cheng K, Zenke M, Keating A, Zhao R
    J Immunol, 2015;194(9):4298-308.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus.
    Authors: Kim J, Kang M, Kim W, Han S, Kim H, Kim H, Kwon K, Kim S, Cha S, Eum S, Koh W, Cho S, Park J, Shin S
    Infect Immun, 2015;83(4):1556-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development.
    Authors: Wang J, Cao Z, Zhang X, Nakamura M, Sun M, Hartman J, Harris R, Sun Y, Cao Y
    Cancer Res, 2015;75(2):306-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Inhibition of Ca2+-independent phospholipase A2beta (iPLA2beta) ameliorates islet infiltration and incidence of diabetes in NOD mice.
    Authors: Bone R, Gai Y, Magrioti V, Kokotou M, Ali T, Lei X, Tse H, Kokotos G, Ramanadham S
    Diabetes, 2015;64(2):541-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.
    Authors: Freeman S, Jaumouille V, Choi K, Hsu B, Wong H, Abraham L, Graves M, Coombs D, Roskelley C, Das R, Grinstein S, Gold M
    Nat Commun, 2015;6(0):6168.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
    Authors: Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang O, Cochran A, Vasser M, Fauber B, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick D, Lill J, Ouyang W, Dixit V
    Nature, 2015;518(7539):417-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  257. CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.
    Authors: Khairnar V, Duhan V, Maney S, Honke N, Shaabani N, Pandyra A, Seifert M, Pozdeev V, Xu H, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf A, Haussinger D, Lang F, Dittmer U, Kuppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Gothert J, Singer B, Lang P, Lang K
    Nat Commun, 2015;6(0):6217.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
    Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
    J Biol Chem, 2015;290(19):12394-402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response.
    Authors: Shan, Chan-Cha, Shi, Liang-Ro, Ding, Mei-Qian, Zhu, Yi-Bei, Li, Xiao-Don, Xu, Bin, Jiang, Jing-Tin, Wu, Chang-Pi
    Oncol Lett, 2015;9(4):1549-1556.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease.
    Authors: Olsan E, Matsushita T, Rezaei M, Weimbs T
    J Biol Chem, 2015;290(25):15679-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.
    Authors: Raich-Regue D, Rosborough B, Watson A, McGeachy M, Turnquist H, Thomson A
    J Immunol, 2015;194(10):4767-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  262. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
    Authors: Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, Deng L, Zanvit P, Tu E, Jin W, Abbatiello B, Goldberg N, Chen Q, Sun L, Zhao K, Chen W
    Nat Immunol, 2015;16(10):1077-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L.
    Authors: Agrawal K, Kale S, Arora N
    Eur J Immunol, 2015;45(12):3375-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  264. Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.
    Authors: Chen, Yan, Zhang, Jin, Lu, Yong, Wang, Libo
    PLoS ONE, 2015;10(4):e0122990.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Lymphocytes from chronically stressed mice confer antidepressant-like effects to naive mice.
    Authors: Brachman R, Lehmann M, Maric D, Herkenham M
    J Neurosci, 2015;35(4):1530-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  266. IRAK-M promotes alternative macrophage activation and fibroproliferation in bleomycin-induced lung injury.
    Authors: Ballinger M, Newstead M, Zeng X, Bhan U, Mo X, Kunkel S, Moore B, Flavell R, Christman J, Standiford T
    J Immunol, 2015;194(4):1894-904.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  267. LKB1 inhibition of NF-kappaB in B cells prevents T follicular helper cell differentiation and germinal center formation.
    Authors: Walsh N, Waters L, Fowler J, Lin M, Cunningham C, Brooks D, Rehg J, Morse H, Teitell M
    EMBO Rep, 2015;16(6):753-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  268. DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4(+) T-cell function without causing severe combined immunodeficiency.
    Authors: Ghonim M, Pyakurel K, Ju J, Rodriguez P, Lammi M, Davis C, Abughazleh M, Mansy M, Naura A, Boulares A
    J Allergy Clin Immunol, 2015;135(2):425-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths.
    Authors: Oeser K, Schwartz C, Voehringer D
    Mucosal Immunol, 2015;8(3):672-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Concentrated protein body product derived from rice endosperm as an oral tolerogen for allergen-specific immunotherapy--a new mucosal vaccine formulation against Japanese cedar pollen allergy.
    Authors: Wakasa Y, Takagi H, Watanabe N, Kitamura N, Fujiwara Y, Ogo Y, Hayashi S, Yang L, Ohta M, Thet Tin W, Sekikawa K, Takano M, Ozawa K, Hiroi T, Takaiwa F
    PLoS ONE, 2015;10(3):e0120209.
    Species: Mouse
    Sample Types: In Vivo
  271. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
    Authors: Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M
    Autophagy, 2015;11(2):271-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  272. An essential role for RGS protein/Galphai2 interactions in B lymphocyte-directed cell migration and trafficking.
    Authors: Hwang I, Park C, Harrison K, Boularan C, Gales C, Kehrl J
    J Immunol, 2015;194(5):2128-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-beta using BV2 microglial cells and APP/PS1 transgenic mice.
    Authors: Latta C, Sudduth T, Weekman E, Brothers H, Abner E, Popa G, Mendenhall M, Gonzalez-Oregon F, Braun K, Wilcock D
    J Neuroinflammation, 2015;12(0):41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  274. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
    Authors: Sag D, Cekic C, Wu R, Linden J, Hedrick C
    Nat Commun, 2015;6(0):6354.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  275. B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.
    Authors: DeMicco A, Naradikian M, Sindhava V, Yoon J, Gorospe M, Wertheim G, Cancro M, Bassing C
    J Immunol, 2015;195(7):3449-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Constraints contributed by chromatin looping limit recombination targeting during Ig class switch recombination.
    Authors: Feldman S, Achour I, Wuerffel R, Kumar S, Gerasimova T, Sen R, Kenter A
    J Immunol, 2015;194(5):2380-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Noncoding RNA transcription targets AID to divergently transcribed loci in B cells.
    Authors: Pefanis, Evangelo, Wang, Jiguang, Rothschild, Gerson, Lim, Junghyun, Chao, Jaime, Rabadan, Raul, Economides, Aris N, Basu, Uttiya
    Nature, 2014;514(7522):389-93.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
    Authors: Colegio O, Chu N, Szabo A, Chu T, Rhebergen A, Jairam V, Cyrus N, Brokowski C, Eisenbarth S, Phillips G, Cline G, Phillips A, Medzhitov R
    Nature, 2014;513(7519):559-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
    Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
    J Immunol, 2014;192(8):3569-81.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Luminex (Standard)
  280. MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
    Authors: Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari N, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S
    J Bone Miner Res, 2014;29(2):290-303.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  281. A role for the ITAM signaling module in specifying cytokine-receptor functions.
    Authors: Bezbradica J, Rosenstein R, DeMarco R, Brodsky I, Medzhitov R
    Nat Immunol, 2014;15(4):333-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  282. Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation.
    Authors: Dufort, Fay J, Gumina, Maria R, Ta, Nathan L, Tao, Yongzhen, Heyse, Shannon, Scott, David A, Richardson, Adam D, Seyfried, Thomas N, Chiles, Thomas C
    J Biol Chem, 2014;289(10):7011-24.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.
    Authors: Dingler F, Kemmerich K, Neuberger M, Rada C
    Eur J Immunol, 2014;44(7):1925-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Binding of AID to DNA does not correlate with mutator activity.
    Authors: Matthews A, Husain S, Chaudhuri J
    J Immunol, 2014;193(1):252-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.
    Authors: Sahin E, Haubenwallner S, Kuttke M, Kollmann I, Halfmann A, Dohnal A, Chen L, Cheng P, Hoesel B, Einwallner E, Brunner J, Kral J, Schrottmaier W, Thell K, Saferding V, Bluml S, Schabbauer G
    J Immunol, 2014;193(4):1717-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo.
    Authors: Cao Q, Wang Y, Zheng D, Sun Y, Wang C, Wang X, Lee V, Wang Y, Zheng G, Tan T, Wang Y, Alexander S, Harris D
    Kidney Int, 2014;85(4):794-806.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia.
    Authors: Rebhandl S, Huemer M, Zaborsky N, Gassner F, Catakovic K, Felder T, Greil R, Geisberger R
    Eur J Immunol, 2014;44(7):2175-87.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  288. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014;4(0):4146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  289. TRAF5 negatively regulates TLR signaling in B lymphocytes.
    Authors: Buchta C, Bishop G
    J Immunol, 2014;192(1):145-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI.
    Authors: Al Faraj, Achraf, Sultana Shaik, Asma, Pureza, Mary Ang, Alnafea, Mohammad, Halwani, Rabih
    PLoS ONE, 2014;9(3):e90829.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide.
    Authors: Han, Ji Eun, Wui, Seo Ri, Kim, Kwang Su, Cho, Yang Je, Cho, Wan Je, Lee, Na Gyong
    PLoS ONE, 2014;9(1):e85838.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  292. IL-17A as an inducer for Th2 immune responses in murine atopic dermatitis models.
    Authors: Nakajima S, Kitoh A, Egawa G, Natsuaki Y, Nakamizo S, Moniaga C, Otsuka A, Honda T, Hanakawa S, Amano W, Iwakura Y, Nakae S, Kubo M, Miyachi Y, Kabashima K
    J Invest Dermatol, 2014;134(8):2122-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.
    Authors: Reynolds C, Chong D, Raynsford E, Quigley K, Kelly D, Llewellyn-Hughes J, Altmann D, Boyton R
    BMC Biol, 2014;12(0):32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1.
    Authors: Asai H, Ikezu S, Woodbury M, Yonemoto G, Cui L, Ikezu T
    Am J Pathol, 2014;184(3):808-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction.
    Authors: Gabriel T, Tol M, Ottenhof R, van Roomen C, Aten J, Claessen N, Hooibrink B, de Weijer B, Serlie M, Argmann C, van Elsenburg L, Aerts J, van Eijk M
    Diabetes, 2014;63(10):3310-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Colony-stimulating factor-1 signaling suppresses renal crystal formation.
    Authors: Taguchi K, Okada A, Kitamura H, Yasui T, Naiki T, Hamamoto S, Ando R, Mizuno K, Kawai N, Tozawa K, Asano K, Tanaka M, Miyoshi I, Kohri K
    J Am Soc Nephrol, 2014;25(8):1680-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Germinal center B cell maintenance and differentiation are controlled by distinct NF-kappaB transcription factor subunits.
    Authors: Heise N, De Silva N, Silva K, Carette A, Simonetti G, Pasparakis M, Klein U
    J Exp Med, 2014;211(10):2103-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2.
    Authors: Park, Mi Kyung, Cho, Min Kyou, Kang, Shin Ae, Park, Hye-Kyun, Kim, Dong-Hee, Yu, Hak Sun
    PLoS ONE, 2014;9(3):e92726.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization.
    Authors: Date D, Das R, Narla G, Simon D, Jain M, Mahabeleshwar G
    J Biol Chem, 2014;289(15):10318-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  300. S100A8 induces IL-10 and protects against acute lung injury.
    Authors: Hiroshima Y, Hsu K, Tedla N, Chung Y, Chow S, Herbert C, Geczy C
    J Immunol, 2014;192(6):2800-11.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. IkappaB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm.
    Authors: Stouch A, Zaynagetdinov R, Barham W, Stinnett A, Slaughter J, Yull F, Hoffman H, Blackwell T, Prince L
    J Immunol, 2014;193(3):1184-93.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Improved repair of dermal wounds in mice lacking microRNA-155.
    Authors: van Solingen C, Araldi E, Chamorro-Jorganes A, Fernandez-Hernando C, Suarez Y
    J Cell Mol Med, 2014;18(6):1104-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
    Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
    Nat Med, 2014;20(4):377-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Role of Blimp-1 in programing Th effector cells into IL-10 producers.
    Authors: Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kuhl A, Heimesaat M, Esser C, Im S, Radbruch A, Rutz S, Scheffold A
    J Exp Med, 2014;211(9):1807-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.
    Authors: Jung I, Shin S, Lee M, Kang T, Han H, Lee S, Kim W, Kim H, Park W, Kim H, Yun C, Lee E, Wu T, Park Y
    J Immunol, 2014;193(3):1233-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  306. DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization.
    Authors: Downey C, Aghaei M, Schwendener R, Jirik F
    PLoS ONE, 2014;9(6):e99988.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Aging is associated with increased regulatory T-cell function.
    Authors: Garg S, Delaney C, Toubai T, Ghosh A, Reddy P, Banerjee R, Yung R
    Aging Cell, 2014;13(3):441-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  308. Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.
    Authors: Hu, Jiazhi, Tepsuporn, Suprawee, Meyers, Robin M, Gostissa, Monica, Alt, Frederic
    Proc Natl Acad Sci U S A, 2014;111(28):10269-74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages.
    Authors: Rajaiah R, Perkins D, Polumuri S, Zhao A, Keegan A, Vogel S
    J Immunol, 2013;190(9):4763-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells.
    Authors: Kim J, Kim W, Choi H, Jang B, Lee K, Park J, Kim H, Cho S, Shin S
    J Leukoc Biol, 2013;94(4):733-49.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  311. The exonuclease Trex1 restrains macrophage proinflammatory activation.
    Authors: Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst A, Lloberas J, Celada A
    J Immunol, 2013;191(12):6128-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  312. TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses.
    Authors: Wang X, Hu Y, Charpentier T, Lamarre A, Qi S, Wu J, Luo H
    J Immunol, 2013;191(11):5420-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation.
    Authors: Leslie K, Song G, Barrick S, Wehbi V, Vilardaga J, Bauer P, Bisello A
    J Biol Chem, 2013;288(51):36426-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency.
    Authors: Umeshappa C, Nanjundappa R, Xie Y, Freywald A, Xu Q, Xiang J
    Immunology, 2013;138(4):298-306.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Rgs13 constrains early B cell responses and limits germinal center sizes.
    Authors: Hwang I, Hwang K, Park C, Harrison K, Kehrl J
    PLoS ONE, 2013;8(3):e60139.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Age- and light-dependent development of localised retinal atrophy in CCL2(-/-)CX3CR1(GFP/GFP) mice.
    Authors: Chen M, Hombrebueno J, Luo C, Penalva R, Zhao J, Colhoun L, Pandi S, Forrester J, Xu H
    PLoS ONE, 2013;8(4):e61381.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis.
    Authors: Dowdle J, Mehta M, Kass E, Vuong B, Inagaki A, Egli D, Jasin M, Keeney S
    PLoS Genet, 2013;9(11):e1003945.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  318. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.
    Authors: Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, Byun J, Kim E, Hwang S, Ju J, Kwok S, Kim H
    Arthritis Rheum, 2013;65(4):949-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity.
    Authors: Palm N, Rosenstein R, Yu S, Schenten D, Florsheim E, Medzhitov R
    Immunity, 2013;39(5):976-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
    Authors: Lam T, Thomas L, White C, Li G, Pone E, Xu Z, Casali P
    PLoS ONE, 2013;8(11):e80414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Functional education of invariant NKT cells by dendritic cell tuning of SHP-1.
    Authors: Napolitano, Anna, Pittoni, Paola, Beaudoin, Lucie, Lehuen, Agnes, Voehringer, David, MacDonald, H Robson, Dellabona, Paolo, Casorati, Giulia
    J Immunol, 2013;190(7):3299-308.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Activated macrophages release microvesicles containing polarized M1 or M2 mRNAs.
    Authors: Garzetti, Livia, Menon, Ramesh, Finardi, Annamari, Bergami, Alessand, Sica, Antonio, Martino, Gianvito, Comi, Giancarl, Verderio, Claudia, Farina, Cinthia, Furlan, Roberto
    J Leukoc Biol, 2013;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses.
    Authors: Jachetti, Elena, Mazzoleni, Stefania, Grioni, Matteo, Ricupito, Alessia, Brambillasca, Chiara, Generoso, Luca, Calcinotto, Arianna, Freschi, Massimo, Mondino, Anna, Galli, Rossella, Bellone, Matteo
    Oncoimmunology, 2013;2(5):e24520.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism.
    Authors: Chattopadhyay, Gouri, Shevach, Ethan M
    J Immunol, 2013;191(12):5875-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  325. Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells.
    Authors: Gao Y, Nish S, Jiang R, Hou L, Licona-Limon P, Weinstein J, Zhao H, Medzhitov R
    Immunity, 2013;39(4):722-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  326. Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.
    Authors: Jacome-Galarza C, Lee S, Lorenzo J, Aguila H
    J Bone Miner Res, 2013;28(5):1203-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  327. IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation.
    Authors: Veremeyko, Tatyana, Siddiqui, Shafiudd, Sotnikov, Ilya, Yung, Amanda, Ponomarev, Eugene D
    PLoS ONE, 2013;8(12):e81774.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.
    Authors: Knosp C, Schiering C, Spence S, Carroll H, Nel H, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald D, Powrie F, Fallon P, Johnston J, Kissenpfennig A
    J Immunol, 2013;190(7):3235-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis.
    Authors: Kumar M, Roe K, Orillo B, Muruve D, Nerurkar V, Gale M, Verma S
    J Virol, 2013;87(7):3655-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration.
    Authors: Gartlan K, Wee J, Demaria M, Nastovska R, Chang T, Jones E, Apostolopoulos V, Pietersz G, Hickey M, van Spriel A, Wright M
    Eur J Immunol, 2013;43(5):1208-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells.
    Authors: Nundel K, Busto P, Debatis M, Marshak-Rothstein A
    J Leukoc Biol, 2013;94(5):865-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  332. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.
    Authors: Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem G, Singh S, Dinda A, Biswal S, Agrawal A, Ghosh B
    Sci Rep, 2013;3(0):1540.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination.
    Authors: Masani, Shahnaz, Han, Li, Yu, Kefei
    Mol Cell Biol, 2013;33(7):1468-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  334. TNFR-Associated Factor 2 Deficiency in B Lymphocytes Predisposes to Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in Mice.
    Authors: Perez-Chacon G, Llobet D, Pardo C, Pindado J, Choi Y, Reed JC, Zapata JM
    J. Immunol., 2012;189(2):1053-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma.
    Authors: Xu Q, Chai S, Qian Y, Zhang M, Wang K
    Acta Pharmacol Sin, 2012;33(12):1525-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  336. Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.
    Authors: Noh KT, Son KH, Jung ID, Kang HK, Hwang SA, Lee WS, You JC, Park YM
    J. Biol. Chem., 2012;287(17):14226-33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  338. Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands.
    Authors: Munich S, Sobo-Vujanovic A, Buchser W, Beer-Stolz D, Vujanovic N
    Oncoimmunology, 2012;1(7):1074-1083.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  339. The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity.
    Authors: Hou J, Liu Y, Liu Y, Shao Y
    PLoS ONE, 2012;7(10):e47724.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  340. CCL25 induces alpha 4 beta 7 integrin-dependent migration of IL-17+ gamma/delta T lymphocytes during an allergic reaction.
    Authors: Costa MF, Bornstein VU, Candea AL, Henriques-Pons A, Henriques MG, Penido C
    Eur. J. Immunol., 2012;42(5):1250-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.
    Nat. Med., 2012;1248(0):18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  342. An epigenetic silencing pathway controlling T helper 2 cell lineage commitment.
    Authors: Allan RS, Zueva E, Cammas F, Schreiber HA, Masson V, Belz GT, Roche D, Maison C, Quivy JP, Almouzni G, Amigorena S
    Nature, 2012;487(7406):249-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  343. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
    Authors: Jin W, Qi S, Luo H
    BMC Immunol., 2011;12(0):68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Oncostatin M induces dendritic cell maturation and Th1 polarization.
    Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
    Biochem. Biophys. Res. Commun., 2010;394(2):272-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  345. Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node.
    Authors: Perona-Wright G, Mohrs K, Mohrs M
    Nat. Immunol., 2010;11(6):520-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  346. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2010;3(1):40-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  347. PEGylation of interleukin-10 for the mitigation of enhanced pain states.
    Authors: Soderquist RG, Milligan ED, Harrison JA, Chavez RA, Johnson KW, Watkins LR, Mahoney MJ
    J Biomed Mater Res A, 2010;93(3):1169-79.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  348. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
    Authors: Chang HC, Sehra S, Goswami R, Yao W, Yu Q, Stritesky GL, Jabeen R, McKinley C, Ahyi AN, Han L, Nguyen ET, Robertson MJ, Perumal NB, Tepper RS, Nutt SL, Kaplan MH
    Nat. Immunol., 2010;11(6):527-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  349. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010;185(4):2502-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
    Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
    J. Immunol., 2010;185(4):2044-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
    Authors: Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S
    J. Virol., 2010;84(24):12703-12.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  352. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
    Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
    J. Exp. Med., 2009;206(1):69-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  353. TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming.
    Authors: Richez C, Yasuda K, Watkins AA
    J. Immunol., 2009;182(2):820-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  354. The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.
    Authors: Claudio E, Sonder SU, Saret S, Carvalho G, Ramalingam TR, Wynn TA, Chariot A, Garcia-Perganeda A, Leonardi A, Paun A, Chen A, Ren NY, Wang H, Siebenlist U
    J. Immunol., 2009;182(3):1617-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  355. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009;11(4):524-30.
  356. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice.
    Authors: McKinley L, Alcorn JF, Peterson A, Dupont RB, Kapadia S, Logar A, Henry A, Irvin CG, Piganelli JD, Ray A, Kolls JK
    J. Immunol., 2008;181(6):4089-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
    Authors: Norman MU, Zbytnuik L, Kubes P
    Eur. J. Immunol., 2008;38(5):1368-80.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  358. Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model.
    Authors: Nakamura M, Jo J, Tabata Y, Ishikawa O
    Am. J. Pathol., 2008;172(3):650-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  359. Direct B cell stimulation by dendritic cells in a mouse model of lupus.
    Authors: Wan S, Zhou Z, Duan B, Morel L
    Arthritis Rheum., 2008;8(0):1741-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  360. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008;125(2):272-9.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  361. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008;112(5):1822-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  362. A mechanism for the initiation of allergen-induced T helper type 2 responses.
    Authors: Sokol CL, Barton GM, Farr AG, Medzhitov R
    Nat. Immunol., 2008;9(3):310-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  363. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance.
    Authors: Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, Belladonna ML, Vacca C, Conte C, Mosci P, Bistoni F, Puccetti P, Kastelein RA, Kopf M, Romani L
    Eur. J. Immunol., 2007;37(10):2695-706.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  364. Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation.
    Authors: Kitamura K, Takeda K, Koya T, Miyahara N, Kodama T, Dakhama A, Takai T, Hirano A, Tanimoto M, Harada M, Gelfand EW
    J. Immunol., 2007;178(1):480-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  365. The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.
    Authors: Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic NL, Li LY
    J. Immunol., 2007;179(6):3742-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Liposomal retinoic acids modulate asthma manifestations in mice.
    Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M
    J. Nutr., 2007;137(12):2730-6.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  367. The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo.
    Authors: Alcaide P, King SL, Dimitroff CJ, Lim YC, Fuhlbrigge RC, Luscinskas FW
    J. Invest. Dermatol., 2007;127(8):1964-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  368. T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways.
    Authors: Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H
    J. Allergy Clin. Immunol., 2007;119(3):662-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  369. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
    Authors: Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F
    J. Clin. Invest., 2007;117(12):3868-3878.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007;26(4):445-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice.
    Authors: King VL, Cassis LA, Daugherty A
    Am. J. Pathol., 2007;171(6):2040-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  372. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
    Authors: Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R
    Mol. Ther., 2007;15(5):971-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.
    Authors: Chiang YM, Chang CL, Chang SL, Yang WC, Shyur LF
    J Ethnopharmacol, 2007;110(3):532-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  374. The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia.
    Authors: Kudlacz E, Conklyn M, Andresen C, Whitney-Pickett C, Changelian P
    Eur. J. Pharmacol., 2007;582(1):154-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  375. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
    Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
    J. Immunol., 2007;178(4):2018-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  376. The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development.
    Authors: Khaled WT, Read EK, Nicholson SE, Baxter FO, Brennan AJ, Came PJ, Sprigg N, McKenzie AN, Watson CJ
    Development, 2007;134(15):2739-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Dendritic cells loaded with apoptotic antibody-coated tumor cells provide protective immunity against B-cell lymphoma in vivo.
    Authors: Franki SN, Steward KK, Betting DJ, Kafi K, Yamada RE, Timmerman JM
    Blood, 2007;111(3):1504-11.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
    Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
    Mol. Cell. Neurosci., 2006;31(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
    Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
    Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis.
    Authors: Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M
    J. Clin. Invest., 2006;116(4):905-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  381. Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile.
    Authors: Wen H, Hogaboam CM, Gauldie J, Kunkel SL
    Am. J. Pathol., 2006;168(6):1940-50.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  382. Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages.
    Authors: Ogawa K, Funaba M, Chen Y, Tsujimoto M
    J. Immunol., 2006;177(10):6787-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  383. 3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation.
    Authors: de la Fuente MA, Kumar L, Lu B, Geha RS
    Mol. Cell. Biol., 2006;26(14):5214-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus.
    Authors: Howell MD, Gallo RL, Boguniewicz M, Jones JF, Wong C, Streib JE, Leung DY
    Immunity, 2006;24(3):341-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  385. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
    Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
    J. Immunol., 2005;174(1):215-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.
    Authors: Harrington, Laurie E, Hatton, Robin D, Mangan, Paul R, Turner, Henriett, Murphy, Theresa, Murphy, Kenneth, Weaver, Casey T
    Nat Immunol, 2005;6(11):1123-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  387. Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
    Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
    Anticancer Res., 2005;25(1):299-303.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  388. IL-1 mediates TNF-induced osteoclastogenesis.
    Authors: Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL
    J. Clin. Invest., 2005;115(2):282-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.
    Authors: Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, Ryffel B, Cambi A, Figdor C, Vainchenker W, Galy A, Caignard A, Zitvogel L
    Blood, 2004;104(10):3267-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004;172(12):7408-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Control of Leishmania major in the absence of Tyk2 kinase.
    Authors: Schleicher U, Mattner J, Blos M, Schindler H, Rollinghoff M, Karaghiosoff M, Muller M, Werner-Felmayer G, Bogdan C
    Eur. J. Immunol., 2004;34(2):519-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  392. Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
    Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
    J. Immunol., 2003;171(10):5107-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  393. P-selectin mediates IL-13-induced eosinophil transmigration but not eotaxin generation in vivo: a comparative study with IL-4-elicited responses.
    Authors: Larbi KY, Dangerfield JP, Culley FJ, Marshall D, Haskard DO, Jose PJ, Williams TJ, Nourshargh S
    J. Leukoc. Biol., 2003;73(1):65-73.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  394. Dual roles of IL-4 in lung injury and fibrosis.
    Authors: Huaux F, Liu T, McGarry B, Ullenbruch M, Phan SH
    J. Immunol., 2003;170(4):2083-92.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  395. AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity.
    Authors: Lukacs NW, Berlin A, Schols D, Skerlj RT, Bridger GJ
    Am. J. Pathol., 2002;160(4):1353-60.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  396. Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation.
    Authors: Morelli AE, Zahorchak AF, Larregina AT
    Blood, 2001;98(5):1512-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  397. The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice.
    Authors: Gyotoku E, Morita E, Kameyoshi Y, Hiragun T, Yamamoto S, Hide M
    Arch. Dermatol. Res., 2001;293(10):508-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  398. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
    Authors: Gabrilovich DI, 2018, Ishida T, Nadaf S, Ohm JE, Carbone DP
    1537, 1999;5(10):2963-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  399. Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-beta.
    Authors: Schmidt A, Zhang X, Joshi R, Iqbal S, Wahlund C, Gabrielsson S, Harris R, Tegner J
    Immunol Cell Biol, 0;94(8):747-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Has recombinant mouse IL-4, Catalog # 404-ML, been tested for activity on human cells?

    • We have not evaluated the bioactivity of Recombinant Mouse IL-4 Protein (Catalog # 404-ML) with human cells. However, we recommend reviewing our list of publications under the Citations tab on the product web page to find reported use of this product with human cells. We do offer a Recombinant Human IL-4 Protein (Catalog # 204-IL), which is suitable for use with human cells.

  2. What concentration of recombinant mouse IL-4, Catalog # 404-ML, should I use for my cell culture experiment?

    • We evaluate the bioactivity of Recombinant Mouse IL-4 Protein (Catalog # 404-ML) in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.5-1.5 ng/mL.  This ED50 range can provide a starting point for your experiment, but we would recommend end-users perform a dose-response to determine the best concentration for their assay system.  We also recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.

       

       

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Reviews for Recombinant Mouse IL-4 Protein

Average Rating: 4.9 (Based on 16 Reviews)

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Recombinant Mouse IL-4 Protein
By Katie Myers on 11/14/2022
Application: Immunoassay Standard

Used as a standard in our mouse ELISA.

Immunoassay Standard Recombinant Mouse IL-4 Protein 404-ML
Recombinant Mouse IL-4 Protein
By Anonymous on 09/29/2021
Application: Enzymatic activity in vitro
Recombinant Mouse IL-4 Protein
By Marina Theodorou on 05/20/2021
Application: CellProlif
Recombinant Mouse IL-4 Protein
By Anonymous on 04/13/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse IL-4 Protein
By Anonymous on 01/27/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse IL-4 Protein
By Anonymous on 01/05/2021
Application: CellProlif
Recombinant Mouse IL-4 Protein
By Anonymous on 01/05/2021
Application: CellProlif
Recombinant Mouse IL-4 Protein
By Gagandeep Kaur on 11/09/2020
Application: CellProlif
Recombinant Mouse IL-4 Protein
By Yu Dang on 10/23/2020
Application: In vitro bioactivity in cell culture
Reason for Rating: IL-4 was used to differentiate THP-1 into M2 phenotype macrophages. We used immunofluorescence staining to show that after treatment the cells are CD206 positive, which means the treatment is successful in the phenotype change of THP-1 into M2 macrophage.

concentration :5ng/ml
Time: 24 h

In vitro bioactivity in cell culture Recombinant Mouse IL-4 Protein 404-ML
Recombinant Mouse IL-4 Protein
By Supriya Sen on 10/06/2020
Application: Immune-cell polarization.
Other Recombinant Mouse IL-4 Protein 404-ML
Recombinant Mouse IL-4 Protein
By Yuqing Feng on 10/16/2019
Application: In vitro bioactivity in cell culture
Recombinant Mouse IL-4 Protein
By Anonymous on 07/13/2018
Application: CellProlif
Recombinant Mouse IL-4 Protein
By Danlee Enzler on 04/02/2018
Application: In vitro bioactivity in cell culture
Recombinant Mouse IL-4 Protein
By Anonymous on 02/07/2018
Application: Binding assay/Protein-protein interaction
Reason for Rating: MAB404 binds rhuIL-13Ra2
Binding assay/Protein-protein interaction Recombinant Mouse IL-4 Protein 404-ML
Recombinant Mouse IL-4 Protein
By Andrew Lechner on 07/21/2016
Application: In vitro bioactivity in cell culture

We used recombinant mouse IL-4 to polarize bonemarrow-derived macrophages to an "M2" phenotype in vitro. We first generated macrophages from whole bone marrow using MCSF-rich media for 7 days. Then we added IL-4 at 20 ng/ml for 48 hours. Using IL-4R wild-type or knock-out bone marrow, we demonstrated using flow cytometry for an M2 reporter (Arginase1-YFP) that the IL-4 acts through the IL-4 receptor to polarize bone marrow derived macrophages towards the M2 phenotype.

In vitro bioactivity in cell culture Recombinant Mouse IL-4 Protein 404-ML
Recombinant Mouse IL-4 Protein
By Tima Thomas on 01/21/2016
Application: In vitro bioactivity in cell culture