Recombinant Porcine Serpin A6/Cortisol Binding Globulin Protein

Novus Biologicals | Catalog # NBP3-57457

Novus Biologicals
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Key Product Details

Applications

Western Blot, ELISA, Cell Culture
View all Serpin A6 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein corresponding to 163 aa of Porcine Serpin A6/Cortisol Binding Globulin.

Source: Yeast

Amino Acid Sequence: EENFYVNETA TVKVPMMFQS RAMKYLNDSL LPCQLVQLEY TGNETAFFIL PVKGEMDTVI AGLSRDTIQR WSKSLIPSQV DLYVPKVSIS GAYDLGSILG DMGIVDLLSH PTHFSGITQN ALPKMSKVVH KAVLQFDEKG MEAAAPTTRG RSLHAAPKPV TVH (163)

Stable for up to 12 months from date of receipt at -20C. Stable for 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles.

Purity

>98%, by SDS-PAGE

Endotoxin Level

No affinity tags & naturally endotoxin-free

Predicted Molecular Mass

17.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Enzyme-linked Immunosorbent Spot (ELISPOT)
ELISA Standard (Matched Pair) (ELISA(Sta))

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation, and Storage

NBP3-57457
Formulation Lyophilized in 1-5X PBS containing 10% Trehalose
Preservative 10% Trehalose
Concentration Lyoph
Reconstitution Reconstitute in sterile PBS with at least 0.1% carrier protein
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Serpin A6

Corticol binding globulin (CBG or transcotin) binds with high affinity to cortisol in plasma. Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

Alternate Names

CBG

Gene Symbol

SERPINA6

Additional Serpin A6 Products

Product Documents for Recombinant Porcine Serpin A6/Cortisol Binding Globulin Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Porcine Serpin A6/Cortisol Binding Globulin Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Serine Proteases and Regulators

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Protocols

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FAQs

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