SREBP2 Antibody (1D2) [Biotin]

Novus Biologicals | Catalog # NBP1-54446B

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Chicken

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Gel Super Shift Assays

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1D2
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Product Specifications

Immunogen

Human SREBP2 protein (amino acids 48-403). [UniProt# Q12772]

Reactivity Notes

Chicken was reported in PMIDs 15333705 and 11907029.

Localization

Endoplasmic reticulum and Golgi apparatus membranes,cytoplasmic vesicle. Mature/processed form localized to nucleus.

Specificity

Recognizes the precursor and mature forms of human SREBP2.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for SREBP2 Antibody (1D2) [Biotin]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Gel Super Shift Assays

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SREBP2

SREBP2 encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Long Name

Sterol Regulatory Element Binding Transcription Factor 2

Alternate Names

bHLhd2, SREBF2

Gene Symbol

SREBF2

Additional SREBP2 Products

Product Documents for SREBP2 Antibody (1D2) [Biotin]

Certificate of Analysis

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Product Specific Notices for SREBP2 Antibody (1D2) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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Associated Pathways

mTOR Signaling Pathway mTOR Signaling Pathway Thumbnail