STAT5b Antibody (1032E) [Janelia Fluor® 525]

Name: STAT5b Antibody (1032E) [Janelia Fluor® 525]
Brand: Novus Biologicals
SKU: FAB15841JF525
Price: 539 USD
Availability: InStock

Novus Biologicals | Catalog # FAB15841JF525

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Product Documents

Recombinant Monoclonal Antibody.

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Knockout Validated, Western Blot, Immunocytochemistry, Immunoprecipitation

Label

Janelia Fluor 525

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1032E

View all STAT5b Primary Antibodies »

Product Specifications

Immunogen

Human STAT5b synthetic peptide aa 777-787
Accession # P51692

Specificity

Detects human, mouse, and rat STAT5b in Western blots.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for STAT5b Antibody (1032E) [Janelia Fluor® 525]

Application

Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: STAT5b

STAT5B is encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Long Name

Signal Transducer and Activator of Transcription 5b

Alternate Names

signal transducer and activator of transcription 5B, STAT5, transcription factor STAT5B

Gene Symbol

STAT5B

Additional STAT5b Products

Product Documents for STAT5b Antibody (1032E) [Janelia Fluor® 525]

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Product Specific Notices for STAT5b Antibody (1032E) [Janelia Fluor® 525]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.