TrkB [p Tyr817] Antibody (SR1158) - BSA Free

Novus Biologicals | Catalog # NBP3-21536

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1158 expressed in HEK293

Format

BSA Free
View all TrkB Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human phospho-TrkB [Tyr817] (Uniprot #: Q16620)

Modification

p Tyr817

Specificity

Detects endogenous levels of phospho-TrkB [Tyr817]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

140 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TrkB [p Tyr817] Antibody (SR1158) - BSA Free

Immunohistochemistry: TrkB [p Tyr 817] Antibody (SR1158) [NBP3-21536] -

Immunohistochemistry: TrkB [p Tyr 817] Antibody (SR1158) [NBP3-21536] - Immunohistochemical analysis of paraffin-embedded mouse brain cancer, using NBP3-21536.

Western Blot: TrkB [p Tyr 817] Antibody (SR1158) [NBP3-21536] -

Western Blot: TrkB [p Tyr 817] Antibody (SR1158) [NBP3-21536] - Western blot analysis using NBP3-21536 in SH-SY5Y cell lysate treated with BDNF.

Applications for TrkB [p Tyr817] Antibody (SR1158) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:100

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:30

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TrkB

TrkB is a tyrosine-protein kinase receptor involved in the development and/or maintenance of the nervous system. TrkB is a receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5, but not nerve growth factor (NGF). The major substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Long Name

Neurotrophic Tyrosine Kinase Receptor B

Alternate Names

NTRK2

Gene Symbol

NTRK2

Additional TrkB Products

Product Documents for TrkB [p Tyr817] Antibody (SR1158) - BSA Free

Certificate of Analysis

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Product Specific Notices for TrkB [p Tyr817] Antibody (SR1158) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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