8 results for "5-HT1A Small Molecules and Peptides" in Products
5-HT1A Small Molecules and Peptides
5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.
Potent 5-HT1A antagonist; also D4 agonist
| Chemical Name: | N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate |
| Purity: | ≥98% |
Potent and selective 5-HT2B and 5-HT2C antagonist; orally active
| Chemical Name: | 3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride |
| Purity: | ≥98% |
CCR2b chemokine receptor antagonist
| Chemical Name: | 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride |
| Purity: | ≥98% |
5-HT1A antagonist
| Chemical Name: | 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide |
| Purity: | ≥98% |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% |
Potent and selective 5-HT1A antagonist
| Chemical Name: | (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide dihydrochloride |
| Purity: | ≥98% |
Highly potent D2-like antagonist; also 5-HT1A agonist
| Alternate Names: | YM 09151,YM 09151-2 |
| Chemical Name: | cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% |
