7 results for "5-HT1B" in Products

5-HT1B Products

5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.

5-HT1B antagonist

Chemical Name: 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride
Purity: ≥98%
5-HT1B antagonist
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Selective h5-HT1B antagonist

Chemical Name: N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride
Purity: ≥98%
Selective h5-HT1B antagonist
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5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist

Chemical Name: 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate
Purity: ≥98%
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
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Selective 5-HT1B antagonist

Chemical Name: 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride
Purity: ≥95%
Selective 5-HT1B antagonist
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Potent and selective 5-HT1B and 5-HT1D antagonist

Chemical Name: N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride
Purity: ≥98%
Potent and selective 5-HT1B and 5-HT1D antagonist
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Selective 5-ht5a antagonist

Chemical Name: N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride
Purity: ≥98%
Selective 5-ht5a antagonist
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Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98%
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
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