9 results for "alpha-1D Adrenergic R/ADRA1D Small Molecules and Peptides" in Products

alpha-1D Adrenergic R/ADRA1D Small Molecules and Peptides

Adrenergic receptors (ARs), including ADRA1D, are key regulators of cardiovascular system function that increase blood pressure and promote vascular remodeling. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the...

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α1 and α2B antagonist; also MT3 antagonist

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride
Purity: ≥98%
α1 and α2B antagonist; also MT3 antagonist
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α1 agonist

Chemical Name: (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
Purity: ≥98%
phenylephrine affects cardiomyocyte contraction rates
(2)
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Potent and non-selective β antagonist; also potent α1 antagonist

Alternate Names: BM 14190
Chemical Name: 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
Purity: ≥98%
Potent and non-selective β antagonist; also potent α1 antagonist
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Selective α1 agonist

Chemical Name: 2-(2-Cyclopropylphenoxymethyl)imidazoline hydrochloride
Purity: ≥98%
Selective α1 agonist
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α1 antagonist; PGK1 activator

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride
Purity: ≥98%
α1 and α2B antagonist (α1 > α2B). Orally active
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Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98%
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
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Highly selective α1 antagonist

Alternate Names: BE 2254
Chemical Name: 2-{[β-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone hydrochloride
Purity: ≥98%
Highly selective α1 antagonist
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α1 antagonist

Alternate Names: UK 33274
Chemical Name: 4-Amino-2-[4-(1,4-benzodioxan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazoline methanesulfonate
Purity: ≥98%
Reduced viability of differentiated cardiomyocytes exposed to cardiotoxic small molecules
(2)
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CCR2b chemokine receptor antagonist

Chemical Name: 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride
Purity: ≥98%
CCR2b chemokine receptor antagonist
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