7 results for "Dopamine D3 R/DRD3" in Products
Dopamine D3 R/DRD3 Products
DRD3 is the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. It is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variations may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing results in transcript variants encoding different isoforms. This variant represents the predominant transcript and encodes the longer isoform (a).
Potent and selective D2 and D3 antagonist
| Chemical Name: | 3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide |
| Purity: | ≥98% |
D2 and D3 antagonist (D3 > D2)
| Alternate Names: | (-)-Eticlopride |
| Chemical Name: | 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride |
| Purity: | ≥98% |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% |
Potent and selective D3 antagonist
| Chemical Name: | N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% |
Selective D3 antagonist
| Chemical Name: | N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamide dihydrochloride |
| Purity: | ≥98% |
Selective D3 antagonist
| Chemical Name: | N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride |
| Purity: | ≥98% |
